(24 nodes) Intestinal epithelial cell differentiation network (Rhinopithecus roxellana)

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

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proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	HIF1A	Hypoxia inducible factor 1 subunit alpha. (826 aa)
	GATA6	GATA binding protein 6. (548 aa)
	PTK6	Tyrosine-protein kinase. (451 aa)
	FZD5	Frizzled class receptor 5; Belongs to the G-protein coupled receptor Fz/Smo family. (585 aa)
	HOXA5	Homeobox A5. (270 aa)
	C1GALT1	Glycoprotein-N-acetylgalactosamine 3-beta-galactosyltransferase 1; Glycosyltransferase that generates the core 1 O-glycan Gal- beta1-3GalNAc-alpha1-Ser/Thr (T antigen), which is a precursor for many extended O-glycans in glycoproteins; Belongs to the glycosyltransferase 31 family. Beta3-Gal-T subfamily. (371 aa)
	SPDEF	SAM pointed domain containing ETS transcription factor. (335 aa)
	PYY	Peptide YY. (97 aa)
	GATA5	GATA binding protein 5. (395 aa)
	NKX3-2	NK3 homeobox 2. (333 aa)
	PRDM1	PR/SET domain 1. (825 aa)
	TYMS	Thymidylate synthetase. (313 aa)
	YAP1	Yes associated protein 1. (508 aa)
	SRC	Tyrosine-protein kinase. (540 aa)
	ENSRROP00000022699	Uncharacterized protein. (356 aa)
	CBFA2T2	CBFA2/RUNX1 partner transcriptional co-repressor 2. (614 aa)
	CDX2	Caudal type homeobox 2. (313 aa)
	YIPF6	Protein YIPF. (236 aa)
	ENSRROP00000029224	Glycoprotein-N-acetylgalactosamine 3-beta-galactosyltransferase 1; Glycosyltransferase that generates the core 1 O-glycan Gal- beta1-3GalNAc-alpha1-Ser/Thr (T antigen), which is a precursor for many extended O-glycans in glycoproteins; Belongs to the glycosyltransferase 31 family. Beta3-Gal-T subfamily. (359 aa)
	SAV1	Salvador family WW domain containing protein 1. (351 aa)
	IL6ST	Interleukin 6 signal transducer. (943 aa)
	TIGAR	TP53 induced glycolysis regulatory phosphatase. (270 aa)
	KLF5	Kruppel like factor 5. (457 aa)
	GATA4	GATA binding protein 4. (417 aa)

Your Current Organism:

Rhinopithecus roxellana

NCBI taxonomy Id: 61622
Other names: Pygathrix roxellana, R. roxellana, golden snub-nosed monkey

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
CDX2	GATA6	ENSRROP00000025324	ENSRROP00000001281	Caudal type homeobox 2.	GATA binding protein 6.	0.571
CDX2	HIF1A	ENSRROP00000025324	ENSRROP00000000494	Caudal type homeobox 2.	Hypoxia inducible factor 1 subunit alpha.	0.564
ENSRROP00000022699	SAV1	ENSRROP00000022699	ENSRROP00000032145	Uncharacterized protein.	Salvador family WW domain containing protein 1.	0.715
ENSRROP00000022699	SRC	ENSRROP00000022699	ENSRROP00000019991	Uncharacterized protein.	Tyrosine-protein kinase.	0.538
GATA6	CDX2	ENSRROP00000001281	ENSRROP00000025324	GATA binding protein 6.	Caudal type homeobox 2.	0.571
HIF1A	CDX2	ENSRROP00000000494	ENSRROP00000025324	Hypoxia inducible factor 1 subunit alpha.	Caudal type homeobox 2.	0.564
HIF1A	PTK6	ENSRROP00000000494	ENSRROP00000001415	Hypoxia inducible factor 1 subunit alpha.	Tyrosine-protein kinase.	0.528
HIF1A	SRC	ENSRROP00000000494	ENSRROP00000019991	Hypoxia inducible factor 1 subunit alpha.	Tyrosine-protein kinase.	0.552
PTK6	HIF1A	ENSRROP00000001415	ENSRROP00000000494	Tyrosine-protein kinase.	Hypoxia inducible factor 1 subunit alpha.	0.528
PTK6	SRC	ENSRROP00000001415	ENSRROP00000019991	Tyrosine-protein kinase.	Tyrosine-protein kinase.	0.544
SAV1	ENSRROP00000022699	ENSRROP00000032145	ENSRROP00000022699	Salvador family WW domain containing protein 1.	Uncharacterized protein.	0.715
SAV1	YAP1	ENSRROP00000032145	ENSRROP00000019863	Salvador family WW domain containing protein 1.	Yes associated protein 1.	0.715
SRC	ENSRROP00000022699	ENSRROP00000019991	ENSRROP00000022699	Tyrosine-protein kinase.	Uncharacterized protein.	0.538
SRC	HIF1A	ENSRROP00000019991	ENSRROP00000000494	Tyrosine-protein kinase.	Hypoxia inducible factor 1 subunit alpha.	0.552
SRC	PTK6	ENSRROP00000019991	ENSRROP00000001415	Tyrosine-protein kinase.	Tyrosine-protein kinase.	0.544
SRC	YAP1	ENSRROP00000019991	ENSRROP00000019863	Tyrosine-protein kinase.	Yes associated protein 1.	0.538
YAP1	SAV1	ENSRROP00000019863	ENSRROP00000032145	Yes associated protein 1.	Salvador family WW domain containing protein 1.	0.715
YAP1	SRC	ENSRROP00000019863	ENSRROP00000019991	Yes associated protein 1.	Tyrosine-protein kinase.	0.538