STRINGSTRING
TGFBR3 TGFBR3 PDGFRB PDGFRB ARID2 ARID2 TBX5 TBX5 SPRED1 SPRED1 SGCD SGCD NRP1 NRP1 TGFBR1 TGFBR1 LRP2 LRP2 SEC24B SEC24B ENSRROP00000037464 ENSRROP00000037464 HAND2 HAND2 SETD2 SETD2 HEY2 HEY2 NOTCH1 NOTCH1
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
TGFBR3Transforming growth factor beta receptor 3. (860 aa)
PDGFRBPlatelet-derived growth factor receptor beta; Tyrosine-protein kinase that acts as cell-surface receptor for homodimeric PDGFB and PDGFD and for heterodimers formed by PDGFA and PDGFB, and plays an essential role in the regulation of embryonic development, cell proliferation, survival, differentiation, chemotaxis and migration. Plays an essential role in blood vessel development by promoting proliferation, migration and recruitment of pericytes and smooth muscle cells to endothelial cells. (1106 aa)
ARID2AT-rich interaction domain 2. (1816 aa)
TBX5T-box transcription factor 5. (518 aa)
SPRED1Sprouty related EVH1 domain containing 1. (444 aa)
SGCDUncharacterized protein. (102 aa)
NRP1Neuropilin; Belongs to the neuropilin family. (923 aa)
TGFBR1Receptor protein serine/threonine kinase; Belongs to the protein kinase superfamily. (498 aa)
LRP2LDL receptor related protein 2. (4655 aa)
SEC24BSEC24 homolog B, COPII coat complex component. (690 aa)
ENSRROP00000037464Uncharacterized protein. (301 aa)
HAND2Heart and neural crest derivatives expressed 2. (287 aa)
SETD2SET domain containing 2, histone lysine methyltransferase. (2563 aa)
HEY2Hes related family bHLH transcription factor with YRPW motif 2. (309 aa)
NOTCH1Notch receptor 1. (2560 aa)
Your Current Organism:
Rhinopithecus roxellana
NCBI taxonomy Id: 61622
Other names: Pygathrix roxellana, R. roxellana, golden snub-nosed monkey
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