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AMHR2 | Anti-Muellerian hormone type-2 receptor; On ligand binding, forms a receptor complex consisting of two type II and two type I transmembrane serine/threonine kinases. Type II receptors phosphorylate and activate type I receptors which autophosphorylate, then bind and activate SMAD transcriptional regulators. Receptor for anti-Muellerian hormone. (573 aa) | ||||
CDK4 | Cyclin dependent kinase 4; Belongs to the protein kinase superfamily. (303 aa) | ||||
PIK3R6 | Phosphoinositide-3-kinase regulatory subunit 6. (464 aa) | ||||
SETD5 | SET domain containing 5. (1462 aa) | ||||
PARD3 | Par-3 family cell polarity regulator. (1325 aa) | ||||
ENSRROP00000010745 | PI3K/PI4K domain-containing protein; Belongs to the PI3/PI4-kinase family. (225 aa) | ||||
PCNA | Proliferating cell nuclear antigen; This protein is an auxiliary protein of DNA polymerase delta and is involved in the control of eukaryotic DNA replication by increasing the polymerase's processibility during elongation of the leading strand; Belongs to the PCNA family. (261 aa) | ||||
POLR2A | DNA-directed RNA polymerase subunit; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. (1992 aa) | ||||
GTF2H3 | General transcription factor IIH subunit 3. (308 aa) | ||||
ZNFX1 | Zinc finger NFX1-type containing 1. (1918 aa) | ||||
TRIM40 | Tripartite motif containing 40. (258 aa) | ||||
POLE | DNA polymerase epsilon catalytic subunit; DNA polymerase II participates in chromosomal DNA replication; Belongs to the DNA polymerase type-B family. (2288 aa) | ||||
POLG2 | DNA polymerase gamma 2, accessory subunit. (485 aa) | ||||
ENSRROP00000007983 | Uncharacterized protein. (380 aa) | ||||
ENSRROP00000007615 | Uncharacterized protein. (466 aa) | ||||
POLR2B | DNA-directed RNA polymerase subunit beta; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. (1174 aa) | ||||
CDK5R1 | Cyclin-dependent kinase 5 activator. (307 aa) | ||||
PIK3R2 | Uncharacterized protein. (647 aa) | ||||
TAF12 | TATA-box binding protein associated factor 12. (213 aa) | ||||
ZBTB7A | Zinc finger and BTB domain containing 7A. (584 aa) | ||||
LOC104681600 | RNA_pol_L_2 domain-containing protein. (133 aa) | ||||
PHKA1 | Phosphorylase b kinase regulatory subunit; Phosphorylase b kinase catalyzes the phosphorylation of serine in certain substrates, including troponin I. Belongs to the phosphorylase b kinase regulatory chain family. (1090 aa) | ||||
POLR3A | DNA-directed RNA polymerase subunit; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. (1397 aa) | ||||
ACVR1 | Serine/threonine-protein kinase receptor; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily. (509 aa) | ||||
CCNG2 | Cyclin G2; Belongs to the cyclin family. (344 aa) | ||||
LOC104660852 | Cyclin-dependent kinases regulatory subunit 1. (79 aa) | ||||
PAF1 | PAF1 homolog, Paf1/RNA polymerase II complex component. (557 aa) | ||||
TAF3 | TATA-box binding protein associated factor 3. (931 aa) | ||||
SOCS3 | Suppressor of cytokine signaling 3. (225 aa) | ||||
CDK14 | Cyclin dependent kinase 14; Belongs to the protein kinase superfamily. (469 aa) | ||||
GTF2E1 | General transcription factor IIE subunit 1. (439 aa) | ||||
POLR2D | RNA polymerase II subunit D. (142 aa) | ||||
STK11 | Serine/threonine kinase 11; Belongs to the protein kinase superfamily. (433 aa) | ||||
ENSRROP00000005618 | Transcription initiation factor IIA subunit 2; TFIIA is a component of the transcription machinery of RNA polymerase II and plays an important role in transcriptional activation; Belongs to the TFIIA subunit 2 family. (105 aa) | ||||
POLR1C | RNA polymerase I and III subunit C. (350 aa) | ||||
TAF6 | TATA-box binding protein associated factor 6. (738 aa) | ||||
TAF6L | TATA-box binding protein associated factor 6 like. (622 aa) | ||||
CCNJ | Cyclin J; Belongs to the cyclin family. (383 aa) | ||||
POLE4 | DNA polymerase epsilon 4, accessory subunit. (129 aa) | ||||
ENSRROP00000000342 | TFIID_NTD2 domain-containing protein. (305 aa) | ||||
ENSRROP00000000351 | Uncharacterized protein. (67 aa) | ||||
TCEA1 | Transcription elongation factor A1. (301 aa) | ||||
ENSRROP00000000820 | Cyclin-dependent kinases regulatory subunit; Binds to the catalytic subunit of the cyclin dependent kinases and is essential for their biological function. (77 aa) | ||||
CKS1B | Cyclin-dependent kinases regulatory subunit; Binds to the catalytic subunit of the cyclin dependent kinases and is essential for their biological function. (79 aa) | ||||
ENSRROP00000000955 | CBFD_NFYB_HMF domain-containing protein. (54 aa) | ||||
TGFB3 | Transforming growth factor beta; Belongs to the TGF-beta family. (412 aa) | ||||
SOCS1 | Suppressor of cytokine signaling 1. (215 aa) | ||||
SUPT3H | SPT3 homolog, SAGA and STAGA complex component. (328 aa) | ||||
IKBKG | Inhibitor of nuclear factor kappa B kinase regulatory subunit gamma. (487 aa) | ||||
TAF11 | TATA-box binding protein associated factor 11. (211 aa) | ||||
ENSRROP00000002311 | Ku domain-containing protein. (539 aa) | ||||
CDC73 | Cell division cycle 73. (531 aa) | ||||
SOCS5 | Suppressor of cytokine signaling 5. (536 aa) | ||||
SOCS6 | Suppressor of cytokine signaling 6. (535 aa) | ||||
TGFBR2 | TGF-beta receptor type-2; Transmembrane serine/threonine kinase forming with the TGF- beta type I serine/threonine kinase receptor, TGFBR1, the non- promiscuous receptor for the TGF-beta cytokines TGFB1, TGFB2 and TGFB3. Transduces the TGFB1, TGFB2 and TGFB3 signal from the cell surface to the cytoplasm and is thus regulating a plethora of physiological and pathological processes including cell cycle arrest in epithelial and hematopoietic cells, control of mesenchymal cell proliferation and differentiation, wound healing, extracellular matrix production, immunosuppression and carcinoge [...] (592 aa) | ||||
TENT2 | Terminal nucleotidyltransferase 2. (484 aa) | ||||
POLA2 | DNA polymerase alpha subunit B; Accessory subunit of the DNA polymerase alpha complex (also known as the alpha DNA polymerase-primase complex) which plays an essential role in the initiation of DNA synthesis. (598 aa) | ||||
SOCS4 | Suppressor of cytokine signaling 4. (439 aa) | ||||
PEX2 | Peroxisomal biogenesis factor 2. (305 aa) | ||||
ACVR2A | Serine/threonine-protein kinase receptor; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily. (513 aa) | ||||
PARD6A | Par-6 family cell polarity regulator alpha. (344 aa) | ||||
ERN1 | Endoplasmic reticulum to nucleus signaling 1. (980 aa) | ||||
NEK10 | NIMA related kinase 10. (1173 aa) | ||||
PRKAB2 | Protein kinase AMP-activated non-catalytic subunit beta 2. (272 aa) | ||||
ENSRROP00000004714 | SOCS box domain-containing protein. (476 aa) | ||||
POLR2F | RNA polymerase II subunit F. (150 aa) | ||||
LOC104674542 | Uncharacterized protein. (264 aa) | ||||
PRPSAP2 | Phosphoribosyl pyrophosphate synthetase associated protein 2. (369 aa) | ||||
GTF2F1 | Transcription initiation factor IIF subunit alpha; TFIIF is a general transcription initiation factor that binds to RNA polymerase II and helps to recruit it to the initiation complex in collaboration with TFIIB. It promotes transcription elongation. Belongs to the TFIIF alpha subunit family. (545 aa) | ||||
CDK13 | Cyclin dependent kinase 13. (1451 aa) | ||||
POLR1E | RNA polymerase I subunit E. (419 aa) | ||||
GTF2F2 | General transcription factor IIF subunit 2; TFIIF is a general transcription initiation factor that binds to RNA polymerase II and helps to recruit it to the initiation complex in collaboration with TFIIB. It promotes transcription elongation. This subunit shows ATP-dependent DNA-helicase activity. (249 aa) | ||||
PIK3CG | Phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit gamma; Belongs to the PI3/PI4-kinase family. (1102 aa) | ||||
NRBF2 | Nuclear receptor binding factor 2. (289 aa) | ||||
MAP3K6 | Mitogen-activated protein kinase kinase kinase 6. (1265 aa) | ||||
ENSRROP00000015144 | Uncharacterized protein. (230 aa) | ||||
CISH | Cytokine inducible SH2 containing protein. (275 aa) | ||||
PRKAG3 | Protein kinase AMP-activated non-catalytic subunit gamma 3. (489 aa) | ||||
POLR1A | DNA-directed RNA polymerase subunit; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. (1754 aa) | ||||
LOC104665405 | Uncharacterized protein; Belongs to the PI3/PI4-kinase family. (583 aa) | ||||
TAF1 | TATA-box binding protein associated factor 1. (1196 aa) | ||||
TAF9B | TATA-box binding protein associated factor 9b. (277 aa) | ||||
XRCC5 | X-ray repair cross-complementing protein 5; Single-stranded DNA-dependent ATP-dependent helicase. Belongs to the ku80 family. (732 aa) | ||||
CCNE1 | Cyclin E1; Belongs to the cyclin family. (410 aa) | ||||
RPRD1B | Regulation of nuclear pre-mRNA domain containing 1B. (326 aa) | ||||
ENSRROP00000016530 | Pribosyltran_N domain-containing protein. (284 aa) | ||||
TERT | Telomerase reverse transcriptase; Telomerase is a ribonucleoprotein enzyme essential for the replication of chromosome termini in most eukaryotes. Active in progenitor and cancer cells. Inactive, or very low activity, in normal somatic cells. Catalytic component of the teleromerase holoenzyme complex whose main activity is the elongation of telomeres by acting as a reverse transcriptase that adds simple sequence repeats to chromosome ends by copying a template sequence within the RNA component of the enzyme. Catalyzes the RNA-dependent extension of 3'-chromosomal termini with the 6-nuc [...] (1132 aa) | ||||
PRPSAP1 | Phosphoribosyl pyrophosphate synthetase associated protein 1. (385 aa) | ||||
CCND1 | Cyclin D1; Belongs to the cyclin family. (253 aa) | ||||
PRPS1 | Pribosyltran_N domain-containing protein. (318 aa) | ||||
CCNY | Cyclin Y; Belongs to the cyclin family. (341 aa) | ||||
ENSRROP00000017569 | Transcription initiation factor IIF subunit alpha; TFIIF is a general transcription initiation factor that binds to RNA polymerase II and helps to recruit it to the initiation complex in collaboration with TFIIB. It promotes transcription elongation. Belongs to the TFIIF alpha subunit family. (442 aa) | ||||
CCNC | Cyclin C; Belongs to the cyclin family. (283 aa) | ||||
CCNE2 | Cyclin E2; Belongs to the cyclin family. (404 aa) | ||||
RPAP2 | RNA polymerase II associated protein 2. (612 aa) | ||||
ENSRROP00000018014 | Protein kinase domain-containing protein. (315 aa) | ||||
PHKB | Phosphorylase b kinase regulatory subunit; Phosphorylase b kinase catalyzes the phosphorylation of serine in certain substrates, including troponin I. Belongs to the phosphorylase b kinase regulatory chain family. (1093 aa) | ||||
LOC104669754 | Uncharacterized protein. (124 aa) | ||||
POLR2G | RNA polymerase II subunit G. (255 aa) | ||||
ATG14 | Autophagy related 14. (492 aa) | ||||
IGF1R | Tyrosine-protein kinase receptor. (1367 aa) | ||||
CCNB3 | Uncharacterized protein; Belongs to the cyclin family. (223 aa) | ||||
SLA2 | Src like adaptor 2. (261 aa) | ||||
POLR3H | RNA polymerase III subunit H. (204 aa) | ||||
CDK5 | Cyclin dependent kinase 5; Belongs to the protein kinase superfamily. (292 aa) | ||||
ENSRROP00000019766 | Uncharacterized protein. (235 aa) | ||||
ACVR1B | Receptor protein serine/threonine kinase; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily. (506 aa) | ||||
ATG101 | Autophagy related 101. (218 aa) | ||||
PHKG2 | Phosphorylase kinase catalytic subunit gamma 2; Belongs to the protein kinase superfamily. (406 aa) | ||||
PHKG1 | Phosphorylase kinase catalytic subunit gamma 1; Belongs to the protein kinase superfamily. (420 aa) | ||||
CTR9 | CTR9 homolog, Paf1/RNA polymerase II complex component. (1173 aa) | ||||
CDKN2D | Cyclin dependent kinase inhibitor 2D. (166 aa) | ||||
RPAP1 | RNA polymerase II associated protein 1. (1393 aa) | ||||
CCNL1 | Cyclin L1; Belongs to the cyclin family. (526 aa) | ||||
PIK3R1 | Phosphoinositide-3-kinase regulatory subunit 1. (724 aa) | ||||
CCNH | Cyclin H; Belongs to the cyclin family. (325 aa) | ||||
ENY2 | Transcription and mRNA export factor ENY2; Involved in mRNA export coupled transcription activation by association with both the TREX-2 and the SAGA complexes. The transcription regulatory histone acetylation (HAT) complex SAGA is a multiprotein complex that activates transcription by remodeling chromatin and mediating histone acetylation and deubiquitination. Within the SAGA complex, participates to a subcomplex that specifically deubiquitinates both histones H2A and H2B. The SAGA complex is recruited to specific gene promoters by activators such as MYC, where it is required for trans [...] (101 aa) | ||||
TAF7L | TATA-box binding protein associated factor 7 like. (463 aa) | ||||
PYDC1 | Pyrin domain containing 1. (89 aa) | ||||
STRADB | STE20 related adaptor beta. (418 aa) | ||||
GNPTG | N-acetylglucosamine-1-phosphate transferase subunit gamma. (305 aa) | ||||
CCND2 | Cyclin N-terminal domain-containing protein; Belongs to the cyclin family. (289 aa) | ||||
PIK3C2B | Phosphatidylinositol-4-phosphate 3-kinase catalytic subunit type 2 beta; Belongs to the PI3/PI4-kinase family. (1634 aa) | ||||
CCNA1 | Cyclin A1; Belongs to the cyclin family. (465 aa) | ||||
POLR1B | Uncharacterized protein. (76 aa) | ||||
PFKM | ATP-dependent 6-phosphofructokinase; Catalyzes the phosphorylation of D-fructose 6-phosphate to fructose 1,6-bisphosphate by ATP, the first committing step of glycolysis; Belongs to the phosphofructokinase type A (PFKA) family. ATP-dependent PFK group I subfamily. Eukaryotic two domain clade 'E' sub-subfamily. (851 aa) | ||||
POLR2J | RNA_pol_L_2 domain-containing protein. (158 aa) | ||||
MNAT1 | CDK-activating kinase assembly factor MAT1; Stabilizes the cyclin H-CDK7 complex to form a functional CDK-activating kinase (CAK) enzymatic complex. (309 aa) | ||||
IKBKE | Inhibitor of nuclear factor kappa B kinase subunit epsilon. (716 aa) | ||||
GTF2A1 | General transcription factor IIA subunit 1. (370 aa) | ||||
CCNA2 | Cyclin A2; Belongs to the cyclin family. (432 aa) | ||||
TGFBR1 | Receptor protein serine/threonine kinase; Belongs to the protein kinase superfamily. (498 aa) | ||||
ENSRROP00000024732 | Uncharacterized protein. (252 aa) | ||||
IKBKB | Inhibitor of nuclear factor kappa B kinase subunit beta. (789 aa) | ||||
LEO1 | LEO1 homolog, Paf1/RNA polymerase II complex component. (666 aa) | ||||
CCNL2 | Cyclin L2; Belongs to the cyclin family. (481 aa) | ||||
POLE3 | DNA polymerase epsilon 3, accessory subunit. (147 aa) | ||||
SOCS7 | Suppressor of cytokine signaling 7. (584 aa) | ||||
PFKL | ATP-dependent 6-phosphofructokinase; Catalyzes the phosphorylation of D-fructose 6-phosphate to fructose 1,6-bisphosphate by ATP, the first committing step of glycolysis; Belongs to the phosphofructokinase type A (PFKA) family. ATP-dependent PFK group I subfamily. Eukaryotic two domain clade 'E' sub-subfamily. (839 aa) | ||||
ENSRROP00000026238 | Uncharacterized protein. (71 aa) | ||||
POLG | DNA polymerase gamma, catalytic subunit. (1230 aa) | ||||
ENSRROP00000026527 | CYCLIN domain-containing protein; Belongs to the cyclin family. (264 aa) | ||||
ACVR2B | Serine/threonine-protein kinase receptor; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily. (525 aa) | ||||
CCNI2 | Cyclin I family member 2; Belongs to the cyclin family. (384 aa) | ||||
CNTD2 | Cyclin N-terminal domain containing 2; Belongs to the cyclin family. (281 aa) | ||||
TBP | TATA-box binding protein. (333 aa) | ||||
POLR3D | RNA polymerase III subunit D. (417 aa) | ||||
LOC104673770 | Proliferating cell nuclear antigen; This protein is an auxiliary protein of DNA polymerase delta and is involved in the control of eukaryotic DNA replication by increasing the polymerase's processibility during elongation of the leading strand; Belongs to the PCNA family. (237 aa) | ||||
RB1CC1 | RB1 inducible coiled-coil 1. (1576 aa) | ||||
ENSRROP00000027148 | Cyclin N-terminal domain-containing protein. (74 aa) | ||||
CDKN1A | Cyclin dependent kinase inhibitor 1A. (164 aa) | ||||
ENSRROP00000027580 | Uncharacterized protein. (220 aa) | ||||
BECN1 | Beclin 1. (450 aa) | ||||
CDK3 | Cyclin dependent kinase 3; Belongs to the protein kinase superfamily. (305 aa) | ||||
PRKAG1 | Protein kinase AMP-activated non-catalytic subunit gamma 1. (331 aa) | ||||
POLR3E | RNA polymerase III subunit E. (709 aa) | ||||
KAT2A | Histone acetyltransferase; Belongs to the acetyltransferase family. GCN5 subfamily. (806 aa) | ||||
POLD4 | Uncharacterized protein. (107 aa) | ||||
ERC1 | ELKS/RAB6-interacting/CAST family member 1. (1120 aa) | ||||
CRCP | CGRP receptor component. (148 aa) | ||||
PFKFB1 | 6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 1. (366 aa) | ||||
ZNRD1 | DNA-directed RNA polymerase subunit; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. Belongs to the archaeal rpoM/eukaryotic RPA12/RPB9/RPC11 RNA polymerase family. (126 aa) | ||||
CCNQ | Cyclin Q; Belongs to the cyclin family. (248 aa) | ||||
GNPTAB | N-acetylglucosamine-1-phosphate transferase subunits alpha and beta. (1256 aa) | ||||
PRKAA1 | Non-specific serine/threonine protein kinase. (697 aa) | ||||
PIK3R4 | Phosphoinositide-3-kinase regulatory subunit 4. (1358 aa) | ||||
CCNT2 | Cyclin T2; Belongs to the cyclin family. (730 aa) | ||||
ENSRROP00000029707 | Cyclin-dependent kinases regulatory subunit; Binds to the catalytic subunit of the cyclin dependent kinases and is essential for their biological function. (64 aa) | ||||
STRADA | STE20 related adaptor alpha. (456 aa) | ||||
TRRAP | Transformation/transcription domain associated protein; Belongs to the PI3/PI4-kinase family. (3860 aa) | ||||
P3R3URF | PIK3R3 upstream reading frame. (95 aa) | ||||
GTF2H5 | General transcription factor IIH subunit 5. (71 aa) | ||||
UVRAG | UV radiation resistance associated. (698 aa) | ||||
CCNI | Cyclin I; Belongs to the cyclin family. (377 aa) | ||||
PRKCI | Protein kinase C; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. PKC subfamily. (596 aa) | ||||
POLD1 | DNA polymerase. (1143 aa) | ||||
SMCR8 | SMCR8-C9orf72 complex subunit. (936 aa) | ||||
CDK10 | Cyclin dependent kinase 10. (198 aa) | ||||
GTF2H2 | General transcription factor IIH subunit. (395 aa) | ||||
PIK3R3 | Phosphoinositide-3-kinase regulatory subunit 3. (461 aa) | ||||
INSR | Tyrosine-protein kinase receptor. (1370 aa) | ||||
CCNO | Cyclin O; Belongs to the cyclin family. (350 aa) | ||||
LOC104655794 | Transcription initiation factor TFIID subunit 13. (124 aa) | ||||
PIK3C3 | Phosphatidylinositol 3-kinase catalytic subunit type 3. (911 aa) | ||||
TAF8 | TATA-box binding protein associated factor 8. (311 aa) | ||||
ENSRROP00000032053 | SCA7 domain-containing protein. (289 aa) | ||||
POLR3K | DNA-directed RNA polymerase subunit; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. Belongs to the archaeal rpoM/eukaryotic RPA12/RPB9/RPC11 RNA polymerase family. (108 aa) | ||||
LOC104681965 | Uncharacterized protein. (222 aa) | ||||
POLR2C | RNA polymerase II subunit C. (275 aa) | ||||
POLA1 | DNA polymerase. (1474 aa) | ||||
POLR2L | RNA polymerase II subunit L. (67 aa) | ||||
SESN2 | Sestrin 2. (518 aa) | ||||
ENSRROP00000044960 | Uncharacterized protein. (257 aa) | ||||
GTF2H4 | General transcription factor IIH subunit 4; Component of the general transcription and DNA repair factor IIH (TFIIH) core complex which is involved in general and transcription-coupled nucleotide excision repair (NER) of damaged DNA. Belongs to the TFB2 family. (462 aa) | ||||
STING1 | Transmembrane protein 173. (379 aa) | ||||
PRKDC | Protein kinase, DNA-activated, catalytic subunit; Belongs to the PI3/PI4-kinase family. (4159 aa) | ||||
TRAF3 | TNF receptor-associated factor; Belongs to the TNF receptor-associated factor family. (568 aa) | ||||
SOCS2 | Suppressor of cytokine signaling 2. (198 aa) | ||||
TADA3 | Transcriptional adaptor 3. (432 aa) | ||||
PIK3CB | Phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit beta; Belongs to the PI3/PI4-kinase family. (1073 aa) | ||||
CCNF | Cyclin F; Belongs to the cyclin family. (786 aa) | ||||
CCNB1 | Cyclin B1; Belongs to the cyclin family. (429 aa) | ||||
ENSRROP00000043070 | BRCA2 and CDKN1A-interacting protein; May promote cell cycle arrest by enhancing the inhibition of CDK2 activity by CDKN1A. May be required for repair of DNA damage by homologous recombination in conjunction with BRCA2. May not be involved in non-homologous end joining (NHEJ); Belongs to the BCP1 family. (299 aa) | ||||
ENY2-2 | Transcription and mRNA export factor ENY2; Involved in mRNA export coupled transcription activation by association with both the TREX-2 and the SAGA complexes. The transcription regulatory histone acetylation (HAT) complex SAGA is a multiprotein complex that activates transcription by remodeling chromatin and mediating histone acetylation and deubiquitination. Within the SAGA complex, participates to a subcomplex that specifically deubiquitinates both histones H2A and H2B. The SAGA complex is recruited to specific gene promoters by activators such as MYC, where it is required for trans [...] (92 aa) | ||||
CCNT1 | Cyclin T1; Belongs to the cyclin family. (728 aa) | ||||
RPRD2 | Regulation of nuclear pre-mRNA domain containing 2. (1518 aa) | ||||
PIK3R5 | Phosphoinositide-3-kinase regulatory subunit 5. (879 aa) | ||||
POLD2 | DNA polymerase delta 2, accessory subunit. (536 aa) | ||||
GTF2H1 | General transcription factor IIH subunit 1. (557 aa) | ||||
TAF5L | TATA-box binding protein associated factor 5 like. (589 aa) | ||||
TAF10 | Transcription initiation factor TFIID subunit 10; TFIID is a multimeric protein complex that plays a central role in mediating promoter responses to various activators and repressors; Belongs to the TAF10 family. (218 aa) | ||||
POLR2K | RNA polymerase II subunit K. (58 aa) | ||||
POLR2E | RNA polymerase II subunit E. (210 aa) | ||||
MYO6 | Myosin VI; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Myosin family. (1294 aa) | ||||
VAC14 | VAC14 component of PIKFYVE complex. (782 aa) | ||||
CDK1 | Cyclin dependent kinase 1; Belongs to the protein kinase superfamily. (297 aa) | ||||
CD3EAP | CD3e molecule associated protein. (512 aa) | ||||
RECQL5 | ATP-dependent DNA helicase; Belongs to the helicase family. RecQ subfamily. (991 aa) | ||||
WDR61 | WD repeat domain 61. (305 aa) | ||||
PRIMPOL | Primase and DNA directed polymerase. (560 aa) | ||||
TBK1 | TANK binding kinase 1. (729 aa) | ||||
TGFB1 | Transforming growth factor beta; Belongs to the TGF-beta family. (391 aa) | ||||
PYCARD | PYD and CARD domain containing. (195 aa) | ||||
TAF4 | TATA-box binding protein associated factor 4. (635 aa) | ||||
DAPK1 | Death associated protein kinase 1. (1430 aa) | ||||
PRIM1 | DNA primase; Belongs to the eukaryotic-type primase small subunit family. (420 aa) | ||||
RTF1 | RTF1 homolog, Paf1/RNA polymerase II complex component. (710 aa) | ||||
POLR3GL | DNA-directed RNA polymerase III subunit; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. Specific peripheric component of RNA polymerase III which synthesizes small RNAs, such as 5S rRNA and tRNAs. (218 aa) | ||||
POLR2I | DNA-directed RNA polymerase subunit; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. Belongs to the archaeal rpoM/eukaryotic RPA12/RPB9/RPC11 RNA polymerase family. (125 aa) | ||||
ENSRROP00000038862 | Protein kinase domain-containing protein. (265 aa) | ||||
GTF2E2 | Transcription initiation factor IIE subunit beta; Recruits TFIIH to the initiation complex and stimulates the RNA polymerase II C-terminal domain kinase and DNA-dependent ATPase activities of TFIIH. Both TFIIH and TFIIE are required for promoter clearance by RNA polymerase. (289 aa) | ||||
PRIM2 | Uncharacterized protein. (158 aa) | ||||
TAF2 | TATA-box binding protein associated factor 2. (1251 aa) | ||||
CHUK | Component of inhibitor of nuclear factor kappa B kinase complex. (745 aa) | ||||
PRKAR2A | Protein kinase cAMP-dependent type II regulatory subunit alpha. (404 aa) | ||||
LOC104671571 | RNA_pol_L_2 domain-containing protein. (133 aa) | ||||
GTF2A2 | Transcription initiation factor IIA subunit 2; TFIIA is a component of the transcription machinery of RNA polymerase II and plays an important role in transcriptional activation; Belongs to the TFIIA subunit 2 family. (109 aa) | ||||
STON1 | Stonin-1; May be involved in the endocytic machinery. (1182 aa) | ||||
POLR3F | DNA-directed RNA polymerase III subunit RPC6; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. Specific peripheric component of RNA polymerase III which synthesizes small RNAs, such as 5S rRNA and tRNAs; Belongs to the eukaryotic RPC34/RPC39 RNA polymerase subunit family. (316 aa) | ||||
CKS2 | Cyclin-dependent kinases regulatory subunit; Binds to the catalytic subunit of the cyclin dependent kinases and is essential for their biological function. (79 aa) | ||||
MMS19 | MMS19 homolog, cytosolic iron-sulfur assembly component. (1030 aa) | ||||
POLR3C | RNA polymerase III subunit C3; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. (534 aa) | ||||
CDK12 | Cyclin dependent kinase 12. (1420 aa) | ||||
TWISTNB | TWIST neighbor. (338 aa) | ||||
TBPL1 | TATA-box binding protein like 1. (186 aa) | ||||
PRKAA2 | Non-specific serine/threonine protein kinase. (560 aa) | ||||
RPRD1A | Regulation of nuclear pre-mRNA domain containing 1A. (337 aa) | ||||
ERCC2 | ERCC excision repair 2, TFIIH core complex helicase subunit. (760 aa) | ||||
ATXN7L3 | Ataxin-7-like protein 3; Component of the transcription regulatory histone acetylation (HAT) complex SAGA, a multiprotein complex that activates transcription by remodeling chromatin and mediating histone acetylation and deubiquitination. Within the SAGA complex, participates in a subcomplex that specifically deubiquitinates both histones H2A and H2B. The SAGA complex is recruited to specific gene promoters by activators such as MYC, where it is required for transcription. Required for nuclear receptor-mediated transactivation. Within the complex, it is required to recruit USP22 and EN [...] (400 aa) | ||||
POLR2H | RNA polymerase II subunit H. (174 aa) | ||||
TAF5 | TATA-box binding protein associated factor 5. (800 aa) | ||||
INSRR | Tyrosine-protein kinase receptor. (1301 aa) | ||||
CDK7 | Cyclin dependent kinase 7; Belongs to the protein kinase superfamily. (346 aa) | ||||
ULK1 | Unc-51 like autophagy activating kinase 1. (1013 aa) | ||||
POLR3B | DNA-directed RNA polymerase subunit beta; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. (1133 aa) | ||||
POLRMT | DNA-directed RNA polymerase; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. Belongs to the phage and mitochondrial RNA polymerase family. (1249 aa) | ||||
CDK9 | Cyclin dependent kinase 9; Belongs to the protein kinase superfamily. (372 aa) | ||||
MAP3K15 | Mitogen-activated protein kinase kinase kinase 15. (1311 aa) | ||||
ENSRROP00000034976 | Cyclin-dependent kinases regulatory subunit; Binds to the catalytic subunit of the cyclin dependent kinases and is essential for their biological function. (121 aa) | ||||
POLD3 | Uncharacterized protein. (466 aa) | ||||
CCND3 | Cyclin D3; Belongs to the cyclin family. (292 aa) | ||||
POLR3G | DNA-directed RNA polymerase III subunit; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. Specific peripheric component of RNA polymerase III which synthesizes small RNAs, such as 5S rRNA and tRNAs. (223 aa) | ||||
CDK16 | Cyclin dependent kinase 16. (570 aa) | ||||
PRKAB1 | Protein kinase AMP-activated non-catalytic subunit beta 1. (270 aa) | ||||
ENSRROP00000036712 | TFIIA_gamma_C domain-containing protein. (74 aa) | ||||
TANK | TRAF family member associated NFKB activator. (457 aa) | ||||
ENSRROP00000037280 | Transcription initiation factor IIA subunit 2; TFIIA is a component of the transcription machinery of RNA polymerase II and plays an important role in transcriptional activation; Belongs to the TFIIA subunit 2 family. (104 aa) | ||||
ATXN7 | SCA7 domain-containing protein. (945 aa) | ||||
CAB39 | Calcium binding protein 39. (341 aa) | ||||
MAP3K5 | Mitogen-activated protein kinase kinase kinase 5. (1374 aa) | ||||
BCCIP | BRCA2 and CDKN1A interacting protein. (323 aa) | ||||
ATG13 | Autophagy-related protein 13; Belongs to the ATG13 family. Metazoan subfamily. (550 aa) | ||||
ENSRROP00000013523 | TAFII28 domain-containing protein. (210 aa) | ||||
REV3L | REV3 like, DNA directed polymerase zeta catalytic subunit. (3128 aa) | ||||
CDK2 | Cyclin dependent kinase 2; Belongs to the protein kinase superfamily. (362 aa) | ||||
MAD2L2 | Mitotic arrest deficient 2 like 2. (224 aa) | ||||
LAS1L | LAS1 like, ribosome biogenesis factor. (738 aa) | ||||
CHRAC1 | Chromatin accessibility complex subunit 1. (131 aa) | ||||
PIK3CD | Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit. (1044 aa) | ||||
PHKA2 | Phosphorylase b kinase regulatory subunit; Phosphorylase b kinase catalyzes the phosphorylation of serine in certain substrates, including troponin I. (1272 aa) | ||||
ACVR1C | Receptor protein serine/threonine kinase; Belongs to the protein kinase superfamily. (396 aa) | ||||
ENSRROP00000012041 | Uncharacterized protein. (204 aa) | ||||
CCNJL | Cyclin J like; Belongs to the cyclin family. (387 aa) | ||||
XRCC6 | X-ray repair cross complementing 6. (617 aa) | ||||
CCNK | Cyclin K; Belongs to the cyclin family. (493 aa) | ||||
PIK3CA | Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit. (1068 aa) | ||||
ENSRROP00000011885 | Uncharacterized protein. (260 aa) | ||||
TAF4B | TATA-box binding protein associated factor 4b. (862 aa) | ||||
POLE2 | DNA polymerase epsilon subunit; Participates in DNA repair and in chromosomal DNA replication; Belongs to the DNA polymerase epsilon subunit B family. (527 aa) | ||||
CDK6 | Cyclin dependent kinase 6; Belongs to the protein kinase superfamily. (326 aa) | ||||
PRKAG2 | Protein kinase AMP-activated non-catalytic subunit gamma 2. (568 aa) |