STRINGSTRING
NFE2L1 NFE2L1 ABCA2 ABCA2 CCR5 CCR5 TGFBR2 TGFBR2 OSBPL7 OSBPL7 MLC1 MLC1 CYP8B1 CYP8B1 SMO SMO GRAMD1A GRAMD1A INHBB INHBB CYP7A1 CYP7A1 LRP8 LRP8 INHBA INHBA GPLD1 GPLD1 SMAD2 SMAD2 TGFBR1 TGFBR1 PTCH1 PTCH1 PMVK PMVK GRAMD1C GRAMD1C DAG1 DAG1 LRP6 LRP6 TGFB1 TGFB1 GRAMD1B GRAMD1B
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
NFE2L1Nuclear factor, erythroid 2 like 1. (772 aa)
ABCA2ATP binding cassette subfamily A member 2. (2310 aa)
CCR5C-C motif chemokine receptor 5 (gene/pseudogene); Belongs to the G-protein coupled receptor 1 family. (352 aa)
TGFBR2TGF-beta receptor type-2; Transmembrane serine/threonine kinase forming with the TGF- beta type I serine/threonine kinase receptor, TGFBR1, the non- promiscuous receptor for the TGF-beta cytokines TGFB1, TGFB2 and TGFB3. Transduces the TGFB1, TGFB2 and TGFB3 signal from the cell surface to the cytoplasm and is thus regulating a plethora of physiological and pathological processes including cell cycle arrest in epithelial and hematopoietic cells, control of mesenchymal cell proliferation and differentiation, wound healing, extracellular matrix production, immunosuppression and carcinoge [...] (592 aa)
OSBPL7Oxysterol-binding protein; Belongs to the OSBP family. (842 aa)
MLC1Modulator of VRAC current 1. (377 aa)
CYP8B1Cytochrome P450 family 8 subfamily B member 1; Belongs to the cytochrome P450 family. (496 aa)
SMOSmoothened, frizzled class receptor; Belongs to the G-protein coupled receptor Fz/Smo family. (786 aa)
GRAMD1AGRAM domain containing 1A. (834 aa)
INHBBInhibin subunit beta B. (396 aa)
CYP7A1Cholesterol 7-alpha-monooxygenase; Belongs to the cytochrome P450 family. (504 aa)
LRP8LDL receptor related protein 8. (959 aa)
INHBAInhibin subunit beta A. (492 aa)
GPLD1Glycosylphosphatidylinositol specific phospholipase D1. (841 aa)
SMAD2Mothers against decapentaplegic homolog. (392 aa)
TGFBR1Receptor protein serine/threonine kinase; Belongs to the protein kinase superfamily. (498 aa)
PTCH1Patched 1. (1448 aa)
PMVKPhosphomevalonate kinase. (192 aa)
GRAMD1CGRAM domain containing 1C. (662 aa)
DAG1Dystroglycan 1. (894 aa)
LRP6Low-density lipoprotein receptor-related protein; Component of the Wnt-Fzd-LRP5-LRP6 complex that triggers beta-catenin signaling through inducing aggregation of receptor-ligand complexes into ribosome-sized signalsomes. Belongs to the LDLR family. (1613 aa)
TGFB1Transforming growth factor beta; Belongs to the TGF-beta family. (391 aa)
GRAMD1BGRAM domain containing 1B. (877 aa)
Your Current Organism:
Rhinopithecus roxellana
NCBI taxonomy Id: 61622
Other names: Pygathrix roxellana, R. roxellana, golden snub-nosed monkey
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