(54 nodes) Mitotic spindle assembly network (Rhinopithecus roxellana)

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

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proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	INCENP	Inner centromere protein. (897 aa)
	ENSRROP00000023864	Uncharacterized protein. (115 aa)
	ARHGEF10	Rho guanine nucleotide exchange factor 10. (1361 aa)
	STAG2	Stromal antigen 2. (1268 aa)
	WRAP73	WD repeat containing, antisense to TP73. (460 aa)
	AURKC	Aurora kinase C; Belongs to the protein kinase superfamily. (309 aa)
	LSM14A	Uncharacterized protein. (468 aa)
	ZNF207	Zinc finger protein 207. (497 aa)
	SMC1A	Structural maintenance of chromosomes protein. (1251 aa)
	ENSRROP00000029157	Uncharacterized protein. (457 aa)
	KIFC1	Kinesin-like protein; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family. (727 aa)
	ENSRROP00000000534	TOG domain-containing protein. (441 aa)
	ZCWPW2	Zinc finger CW-type and PWWP domain containing 2. (356 aa)
	RACGAP1	Rac GTPase activating protein 1. (632 aa)
	TASOR	Transcription activation suppressor. (1519 aa)
	KIF23	Kinesin-like protein; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family. (960 aa)
	CEP192	Centrosomal protein 192. (2539 aa)
	SMC3	Structural maintenance of chromosomes protein. (1217 aa)
	MAP9	Microtubule associated protein 9. (647 aa)
	ENSRROP00000043070	BRCA2 and CDKN1A-interacting protein; May promote cell cycle arrest by enhancing the inhibition of CDK2 activity by CDKN1A. May be required for repair of DNA damage by homologous recombination in conjunction with BRCA2. May not be involved in non-homologous end joining (NHEJ); Belongs to the BCP1 family. (299 aa)
	TOGARAM1	TOG domain-containing protein. (624 aa)
	CLASP1	Cytoplasmic linker associated protein 1. (1552 aa)
	KIFC2	Kinesin-like protein; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family. (821 aa)
	FLNA	Filamin A. (2647 aa)
	ABRAXAS2	Abraxas 2, BRISC complex subunit. (415 aa)
	TOGARAM2	TOG array regulator of axonemal microtubules 2. (1019 aa)
	KIF11	Kinesin family member 11; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family. (1056 aa)
	AAAS	Aladin WD repeat nucleoporin. (546 aa)
	PIBF1	Progesterone immunomodulatory binding factor 1. (757 aa)
	GOLGA2	Golgin A2. (1090 aa)
	AURKB	Aurora kinase B; Belongs to the protein kinase superfamily. (344 aa)
	MISP	Mitotic spindle positioning. (679 aa)
	MZT1	Mitotic spindle organizing protein 1. (82 aa)
	ENSRROP00000020971	Uncharacterized protein. (376 aa)
	STAG1	Stromal antigen 1. (1291 aa)
	ENSRROP00000020473	FFD domain-containing protein. (348 aa)
	PRC1	Protein regulator of cytokinesis 1. (717 aa)
	ENSRROP00000018712	Uncharacterized protein. (300 aa)
	SPICE1	Uncharacterized protein. (856 aa)
	ENSRROP00000017997	Uncharacterized protein. (654 aa)
	CCDC61	Coiled-coil domain containing 61. (512 aa)
	TPX2	TPX2 microtubule nucleation factor. (727 aa)
	RHOA	Ras homolog family member A. (193 aa)
	MYBL2	Uncharacterized protein. (868 aa)
	BCCIP	BRCA2 and CDKN1A interacting protein. (323 aa)
	CLASP2	Uncharacterized protein. (1517 aa)
	NEK2	NIMA related kinase 2. (445 aa)
	KPNB1	Karyopherin subunit beta 1. (870 aa)
	CDC20	Cell division cycle 20. (499 aa)
	POLDIP2	DNA polymerase delta interacting protein 2. (375 aa)
	KIF3B	Kinesin-like protein; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family. (747 aa)
	KIF4A	Kinesin family member 4A; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family. (1234 aa)
	CHEK2	Checkpoint kinase 2. (589 aa)
	ABRAXAS1	Abraxas 1, BRCA1 A complex subunit. (409 aa)

Your Current Organism:

Rhinopithecus roxellana

NCBI taxonomy Id: 61622
Other names: Pygathrix roxellana, R. roxellana, golden snub-nosed monkey

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
AAAS	INCENP	ENSRROP00000033267	ENSRROP00000012324	Aladin WD repeat nucleoporin.	Inner centromere protein.	0.539
AAAS	RHOA	ENSRROP00000033267	ENSRROP00000015417	Aladin WD repeat nucleoporin.	Ras homolog family member A.	0.424
ABRAXAS1	CHEK2	ENSRROP00000010058	ENSRROP00000022798	Abraxas 1, BRCA1 A complex subunit.	Checkpoint kinase 2.	0.596
AURKB	AURKC	ENSRROP00000030540	ENSRROP00000026757	Aurora kinase B; Belongs to the protein kinase superfamily.	Aurora kinase C; Belongs to the protein kinase superfamily.	0.581
AURKB	CDC20	ENSRROP00000030540	ENSRROP00000011097	Aurora kinase B; Belongs to the protein kinase superfamily.	Cell division cycle 20.	0.848
AURKB	CEP192	ENSRROP00000030540	ENSRROP00000003370	Aurora kinase B; Belongs to the protein kinase superfamily.	Centrosomal protein 192.	0.456
AURKB	INCENP	ENSRROP00000030540	ENSRROP00000012324	Aurora kinase B; Belongs to the protein kinase superfamily.	Inner centromere protein.	0.981
AURKB	KIF11	ENSRROP00000030540	ENSRROP00000033286	Aurora kinase B; Belongs to the protein kinase superfamily.	Kinesin family member 11; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family.	0.762
AURKB	KIF23	ENSRROP00000030540	ENSRROP00000003153	Aurora kinase B; Belongs to the protein kinase superfamily.	Kinesin-like protein; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family.	0.644
AURKB	KIF4A	ENSRROP00000030540	ENSRROP00000021048	Aurora kinase B; Belongs to the protein kinase superfamily.	Kinesin family member 4A; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family.	0.563
AURKB	KIFC1	ENSRROP00000030540	ENSRROP00000045242	Aurora kinase B; Belongs to the protein kinase superfamily.	Kinesin-like protein; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family.	0.655
AURKB	NEK2	ENSRROP00000030540	ENSRROP00000012483	Aurora kinase B; Belongs to the protein kinase superfamily.	NIMA related kinase 2.	0.668
AURKB	PRC1	ENSRROP00000030540	ENSRROP00000019144	Aurora kinase B; Belongs to the protein kinase superfamily.	Protein regulator of cytokinesis 1.	0.581
AURKB	RACGAP1	ENSRROP00000030540	ENSRROP00000001867	Aurora kinase B; Belongs to the protein kinase superfamily.	Rac GTPase activating protein 1.	0.639
AURKB	TPX2	ENSRROP00000030540	ENSRROP00000016980	Aurora kinase B; Belongs to the protein kinase superfamily.	TPX2 microtubule nucleation factor.	0.565
AURKB	ZCWPW2	ENSRROP00000030540	ENSRROP00000000787	Aurora kinase B; Belongs to the protein kinase superfamily.	Zinc finger CW-type and PWWP domain containing 2.	0.550
AURKC	AURKB	ENSRROP00000026757	ENSRROP00000030540	Aurora kinase C; Belongs to the protein kinase superfamily.	Aurora kinase B; Belongs to the protein kinase superfamily.	0.581
AURKC	CDC20	ENSRROP00000026757	ENSRROP00000011097	Aurora kinase C; Belongs to the protein kinase superfamily.	Cell division cycle 20.	0.765
AURKC	CEP192	ENSRROP00000026757	ENSRROP00000003370	Aurora kinase C; Belongs to the protein kinase superfamily.	Centrosomal protein 192.	0.456
AURKC	ENSRROP00000023864	ENSRROP00000026757	ENSRROP00000023864	Aurora kinase C; Belongs to the protein kinase superfamily.	Uncharacterized protein.	0.576