65 items (Rhinopithecus roxellana) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	ADCY6	Adenylate cyclase 6; Belongs to the adenylyl cyclase class-4/guanylyl cyclase family. (603 aa)
	GNAZ	G protein subunit alpha z. (355 aa)
	HTR1F	5-hydroxytryptamine receptor 1F. (366 aa)
	HTR3E	5-hydroxytryptamine receptor 3E; Belongs to the ligand-gated ion channel (TC 1.A.9) family. (463 aa)
	HRH1	Histamine receptor H1; Belongs to the G-protein coupled receptor 1 family. (489 aa)
	GNG2	Guanine nucleotide-binding protein subunit gamma; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction. (110 aa)
	ADCY5	Adenylate cyclase 5; Belongs to the adenylyl cyclase class-4/guanylyl cyclase family. (864 aa)
	HTR1B	5-hydroxytryptamine receptor 1B. (390 aa)
	GSK3A	Glycogen synthase kinase 3 alpha; Belongs to the protein kinase superfamily. (428 aa)
	HTR1E	5-hydroxytryptamine receptor 1E. (365 aa)
	HTR3D	5-hydroxytryptamine receptor 3D. (377 aa)
	CHRM3	Muscarinic acetylcholine receptor; The muscarinic acetylcholine receptor mediates various cellular responses, including inhibition of adenylate cyclase, breakdown of phosphoinositides and modulation of potassium channels through the action of G proteins. (590 aa)
	CHRM4	Muscarinic acetylcholine receptor; The muscarinic acetylcholine receptor mediates various cellular responses, including inhibition of adenylate cyclase, breakdown of phosphoinositides and modulation of potassium channels through the action of G proteins. (479 aa)
	NSG1	Neuronal vesicle trafficking associated 1. (185 aa)
	CHRM5	Muscarinic acetylcholine receptor; The muscarinic acetylcholine receptor mediates various cellular responses, including inhibition of adenylate cyclase, breakdown of phosphoinositides and modulation of potassium channels through the action of G proteins. (532 aa)
	ATF4	Activating transcription factor 4. (351 aa)
	HRH3	Histamine receptor H3; Belongs to the G-protein coupled receptor 1 family. (439 aa)
	GNAS	GNAS complex locus. (1041 aa)
	LOC104663799	Uncharacterized protein. (246 aa)
	HTR2C	5-hydroxytryptamine receptor 2C. (295 aa)
	LRRK2	Leucine rich repeat kinase 2. (2527 aa)
	FLNA	Filamin A. (2647 aa)
	HTR4	5-hydroxytryptamine receptor 4; Belongs to the G-protein coupled receptor 1 family. (428 aa)
	DNM2	Dynamin 2; Belongs to the TRAFAC class dynamin-like GTPase superfamily. Dynamin/Fzo/YdjA family. (875 aa)
	HCN3	Hyperpolarization activated cyclic nucleotide gated potassium channel 3. (774 aa)
	HTR3C	5-hydroxytryptamine receptor 3C; Belongs to the ligand-gated ion channel (TC 1.A.9) family. (438 aa)
	MAPK3	Mitogen-activated protein kinase; Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. MAP kinase subfamily. (379 aa)
	GNB5	G protein subunit beta 5. (403 aa)
	HTR2B	5-hydroxytryptamine receptor 2B. (481 aa)
	HTR1A	5-hydroxytryptamine receptor 1A. (422 aa)
	CHRM2	Muscarinic acetylcholine receptor; The muscarinic acetylcholine receptor mediates various cellular responses, including inhibition of adenylate cyclase, breakdown of phosphoinositides and modulation of potassium channels through the action of G proteins. (466 aa)
	DRD4	Dopamine receptor D4; Belongs to the G-protein coupled receptor 1 family. (326 aa)
	GNA14	G protein subunit alpha 14. (355 aa)
	DRD1	Dopamine receptor D1; Belongs to the G-protein coupled receptor 1 family. (446 aa)
	CALY	Calcyon neuron specific vesicular protein. (217 aa)
	MAPK1	Mitogen-activated protein kinase. (330 aa)
	HTR3A	5-hydroxytryptamine receptor 3A; Belongs to the ligand-gated ion channel (TC 1.A.9) family. (520 aa)
	GNA15	G protein subunit alpha 15. (374 aa)
	PTGER1	Prostaglandin E receptor 1. (402 aa)
	TGM2	Transglutaminase 2. (731 aa)
	OR10J5	Olfactory receptor family 10 subfamily J member 5. (226 aa)
	DRD3	Dopamine receptor D3; Belongs to the G-protein coupled receptor 1 family. (400 aa)
	GABPA	GA binding protein transcription factor subunit alpha. (454 aa)
	LOC104664017	G protein subunit alpha o1. (317 aa)
	GNAL	G protein subunit alpha L. (448 aa)
	ID1	Inhibitor of DNA binding 1, HLH protein. (154 aa)
	HDAC2	Histone deacetylase 2; Responsible for the deacetylation of lysine residues on the N-terminal part of the core histones (H2A, H2B, H3 and H4). Histone deacetylation gives a tag for epigenetic repression and plays an important role in transcriptional regulation, cell cycle progression and developmental events. Histone deacetylases act via the formation of large multiprotein complexes. (488 aa)
	NCSTN	Nicastrin. (709 aa)
	HRH2	Histamine receptor H2; Belongs to the G-protein coupled receptor 1 family. (422 aa)
	GNA11	G protein subunit alpha 11. (359 aa)
	SLC1A1	Amino acid transporter. (524 aa)
	NSG2	Neuronal vesicle trafficking associated 2. (171 aa)
	HTR6	5-hydroxytryptamine receptor 6; Belongs to the G-protein coupled receptor 1 family. (440 aa)
	HTR7	5-hydroxytryptamine receptor 7; Belongs to the G-protein coupled receptor 1 family. (479 aa)
	PRKN	E3 ubiquitin-protein ligase parkin; Functions within a multiprotein E3 ubiquitin ligase complex, catalyzing the covalent attachment of ubiquitin moieties onto substrate proteins; Belongs to the RBR family. Parkin subfamily. (465 aa)
	ENSRROP00000009633	G_PROTEIN_RECEP_F1_2 domain-containing protein. (146 aa)
	HTR5A	5-hydroxytryptamine receptor 5A. (357 aa)
	HTR2A	5-hydroxytryptamine receptor 2A. (472 aa)
	HTR1D	5-hydroxytryptamine receptor 1D. (377 aa)
	ABL1	Tyrosine-protein kinase. (1149 aa)
	HTR3B	5-hydroxytryptamine receptor 3B; Belongs to the ligand-gated ion channel (TC 1.A.9) family. (441 aa)
	HRH4	Histamine receptor H4; Belongs to the G-protein coupled receptor 1 family. (390 aa)
	SIN3A	SIN3 transcription regulator family member A. (1273 aa)
	DRD2	Dopamine receptor D2; Belongs to the G-protein coupled receptor 1 family. (443 aa)
	ENSRROP00000041922	Uncharacterized protein. (115 aa)

Your Current Organism:

Rhinopithecus roxellana

NCBI taxonomy Id: 61622
Other names: Pygathrix roxellana, R. roxellana, golden snub-nosed monkey

Send network to Cytoscape

Export your current network:

... as a bitmap image:

download

file format is 'PNG': portable network graphic

... as a high-resolution bitmap:

download

same PNG format, but at higher resolution

... as a vector graphic:

download

SVG: scalable vector graphic - can be opened and edited in Illustrator, CorelDraw, Dia, etc

... as short tabular text output:

download

TSV: tab separated values - can be opened in Excel and Cytoscape (lists only one-way edges: A-B)

... as tabular text output:

download

TSV: tab separated values - can be opened in Excel (lists reciprocal edges: A-B,B-A)

... as an XML summary:

download

structured XML interaction data, according to the 'PSI-MI' data standard

... protein node degrees:

download

node degree of proteins in your network (given the current score cut-off)

... network coordinates:

download

a flat-file format describing the coordinates and colors of nodes in the network

... protein sequences:

download

MFA: multi-fasta format - containing the aminoacid sequences in the network

... protein annotations:

download

a tab-delimited file describing the names, domains and descriptions of proteins in your network

... functional annotations:

download

a tab-delimited file containing all known functional terms of protiens in your network

Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
ABL1	LOC104663799	ENSRROP00000016398	ENSRROP00000037956	Tyrosine-protein kinase.	Uncharacterized protein.	0.527
ABL1	MAPK1	ENSRROP00000016398	ENSRROP00000024767	Tyrosine-protein kinase.	Mitogen-activated protein kinase.	0.570
ABL1	MAPK3	ENSRROP00000016398	ENSRROP00000032094	Tyrosine-protein kinase.	Mitogen-activated protein kinase; Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. MAP kinase subfamily.	0.485
ADCY5	ADCY6	ENSRROP00000003576	ENSRROP00000040839	Adenylate cyclase 5; Belongs to the adenylyl cyclase class-4/guanylyl cyclase family.	Adenylate cyclase 6; Belongs to the adenylyl cyclase class-4/guanylyl cyclase family.	0.941
ADCY5	GNAL	ENSRROP00000003576	ENSRROP00000018429	Adenylate cyclase 5; Belongs to the adenylyl cyclase class-4/guanylyl cyclase family.	G protein subunit alpha L.	0.976
ADCY5	GNAS	ENSRROP00000003576	ENSRROP00000038847	Adenylate cyclase 5; Belongs to the adenylyl cyclase class-4/guanylyl cyclase family.	GNAS complex locus.	0.976
ADCY5	GNAZ	ENSRROP00000003576	ENSRROP00000008482	Adenylate cyclase 5; Belongs to the adenylyl cyclase class-4/guanylyl cyclase family.	G protein subunit alpha z.	0.550
ADCY5	GNB5	ENSRROP00000003576	ENSRROP00000031461	Adenylate cyclase 5; Belongs to the adenylyl cyclase class-4/guanylyl cyclase family.	G protein subunit beta 5.	0.948
ADCY5	GNG2	ENSRROP00000003576	ENSRROP00000003513	Adenylate cyclase 5; Belongs to the adenylyl cyclase class-4/guanylyl cyclase family.	Guanine nucleotide-binding protein subunit gamma; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction.	0.485
ADCY5	LOC104663799	ENSRROP00000003576	ENSRROP00000037956	Adenylate cyclase 5; Belongs to the adenylyl cyclase class-4/guanylyl cyclase family.	Uncharacterized protein.	0.903
ADCY5	LOC104664017	ENSRROP00000003576	ENSRROP00000018942	Adenylate cyclase 5; Belongs to the adenylyl cyclase class-4/guanylyl cyclase family.	G protein subunit alpha o1.	0.559
ADCY6	ADCY5	ENSRROP00000040839	ENSRROP00000003576	Adenylate cyclase 6; Belongs to the adenylyl cyclase class-4/guanylyl cyclase family.	Adenylate cyclase 5; Belongs to the adenylyl cyclase class-4/guanylyl cyclase family.	0.941
ADCY6	GNAL	ENSRROP00000040839	ENSRROP00000018429	Adenylate cyclase 6; Belongs to the adenylyl cyclase class-4/guanylyl cyclase family.	G protein subunit alpha L.	0.743
ADCY6	GNAS	ENSRROP00000040839	ENSRROP00000038847	Adenylate cyclase 6; Belongs to the adenylyl cyclase class-4/guanylyl cyclase family.	GNAS complex locus.	0.980
ADCY6	GNAZ	ENSRROP00000040839	ENSRROP00000008482	Adenylate cyclase 6; Belongs to the adenylyl cyclase class-4/guanylyl cyclase family.	G protein subunit alpha z.	0.550
ADCY6	GNB5	ENSRROP00000040839	ENSRROP00000031461	Adenylate cyclase 6; Belongs to the adenylyl cyclase class-4/guanylyl cyclase family.	G protein subunit beta 5.	0.820
ADCY6	GNG2	ENSRROP00000040839	ENSRROP00000003513	Adenylate cyclase 6; Belongs to the adenylyl cyclase class-4/guanylyl cyclase family.	Guanine nucleotide-binding protein subunit gamma; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction.	0.412
ADCY6	LOC104663799	ENSRROP00000040839	ENSRROP00000037956	Adenylate cyclase 6; Belongs to the adenylyl cyclase class-4/guanylyl cyclase family.	Uncharacterized protein.	0.903
ADCY6	LOC104664017	ENSRROP00000040839	ENSRROP00000018942	Adenylate cyclase 6; Belongs to the adenylyl cyclase class-4/guanylyl cyclase family.	G protein subunit alpha o1.	0.470
ATF4	MAPK1	ENSRROP00000007388	ENSRROP00000024767	Activating transcription factor 4.	Mitogen-activated protein kinase.	0.902