STRINGSTRING
RARB RARB NR2E1 NR2E1 NF1 NF1 CD109 CD109 CDKN2C CDKN2C KDF1 KDF1 FBLN1 FBLN1 FERMT1 FERMT1 NFIB NFIB OVOL2 OVOL2 TP53 TP53 GLI3 GLI3 RARG RARG IRF6 IRF6 SNAI2 SNAI2 WNT11 WNT11 OVOL1 OVOL1 FGF10 FGF10 SFN SFN PTCH1 PTCH1
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
RARBRetinoic acid receptor beta. (448 aa)
NR2E1Nuclear receptor subfamily 2 group E member 1. (421 aa)
NF1Neurofibromin 1. (2821 aa)
CD109CD109 molecule. (1449 aa)
CDKN2CCyclin dependent kinase inhibitor 2C. (168 aa)
KDF1Keratinocyte differentiation factor 1. (398 aa)
FBLN1Fibulin-1; Incorporated into fibronectin-containing matrix fibers. May play a role in cell adhesion and migration along protein fibers within the extracellular matrix (ECM). Could be important for certain developmental processes and contribute to the supramolecular organization of ECM architecture, in particular to those of basement membranes. (710 aa)
FERMT1Fermitin family member 1. (626 aa)
NFIBNuclear factor 1; Recognizes and binds the palindromic sequence 5'- TTGGCNNNNNGCCAA-3' present in viral and cellular promoters and in the origin of replication of adenovirus type 2. These proteins are individually capable of activating transcription and replication. (561 aa)
OVOL2Ovo like zinc finger 2. (275 aa)
TP53Cellular tumor antigen p53; Acts as a tumor suppressor in many tumor types; induces growth arrest or apoptosis depending on the physiological circumstances and cell type. Involved in cell cycle regulation as a trans-activator that acts to negatively regulate cell division by controlling a set of genes required for this process. One of the activated genes is an inhibitor of cyclin-dependent kinases. Apoptosis induction seems to be mediated either by stimulation of BAX and FAS antigen expression, or by repression of Bcl-2 expression; Belongs to the p53 family. (393 aa)
GLI3GLI family zinc finger 3. (1580 aa)
RARGRetinoic acid receptor gamma. (456 aa)
IRF6Interferon regulatory factor 6. (467 aa)
SNAI2Snail family transcriptional repressor 2. (268 aa)
WNT11Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (354 aa)
OVOL1Ovo like transcriptional repressor 1. (275 aa)
FGF10Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (208 aa)
SFNStratifin; Belongs to the 14-3-3 family. (248 aa)
PTCH1Patched 1. (1448 aa)
Your Current Organism:
Rhinopithecus roxellana
NCBI taxonomy Id: 61622
Other names: Pygathrix roxellana, R. roxellana, golden snub-nosed monkey
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