STRINGSTRING
YPEL3 YPEL3 PAWR PAWR CGAS CGAS KIR2DL4 KIR2DL4 ABI3 ABI3 TP53 TP53 YPEL4 YPEL4 EEF1E1 EEF1E1 ARG2 ARG2 SIRT1 SIRT1 ENSRROP00000014834 ENSRROP00000014834 B2M B2M MORC3 MORC3 KIR3DL3 KIR3DL3
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
YPEL3Protein yippee-like; Belongs to the yippee family. (157 aa)
PAWRPro-apoptotic WT1 regulator. (340 aa)
CGASCyclic GMP-AMP synthase. (523 aa)
KIR2DL4Uncharacterized protein. (237 aa)
ABI3ABI family member 3. (366 aa)
TP53Cellular tumor antigen p53; Acts as a tumor suppressor in many tumor types; induces growth arrest or apoptosis depending on the physiological circumstances and cell type. Involved in cell cycle regulation as a trans-activator that acts to negatively regulate cell division by controlling a set of genes required for this process. One of the activated genes is an inhibitor of cyclin-dependent kinases. Apoptosis induction seems to be mediated either by stimulation of BAX and FAS antigen expression, or by repression of Bcl-2 expression; Belongs to the p53 family. (393 aa)
YPEL4Protein yippee-like; Belongs to the yippee family. (127 aa)
EEF1E1GST C-terminal domain-containing protein. (174 aa)
ARG2Arginase. (354 aa)
SIRT1Sirtuin 1. (746 aa)
ENSRROP00000014834GST C-terminal domain-containing protein. (168 aa)
B2MBeta-2-microglobulin; Component of the class I major histocompatibility complex (MHC). Involved in the presentation of peptide antigens to the immune system. (119 aa)
MORC3MORC family CW-type zinc finger 3. (939 aa)
KIR3DL3Killer cell immunoglobulin like receptor, three Ig domains and long cytoplasmic tail 3. (428 aa)
Your Current Organism:
Rhinopithecus roxellana
NCBI taxonomy Id: 61622
Other names: Pygathrix roxellana, R. roxellana, golden snub-nosed monkey
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