STRINGSTRING
SNRPG-2 SNRPG-2 RNF113A RNF113A YJU2 YJU2 LOC104657389 LOC104657389 SNRPD1 SNRPD1 SNRNP40 SNRNP40 CDC40 CDC40 ENSRROP00000010290 ENSRROP00000010290 ENSRROP00000010844 ENSRROP00000010844 IK IK LOC104672089 LOC104672089 SRRM2 SRRM2 ENSRROP00000013502 ENSRROP00000013502 SNRPF SNRPF U2AF2 U2AF2 SNRPD3 SNRPD3 LOC104669438 LOC104669438 SNRPB2 SNRPB2 EFL1 EFL1 DHX16 DHX16 ENSRROP00000015661 ENSRROP00000015661 ENSRROP00000016405 ENSRROP00000016405 ZMAT2 ZMAT2 PRPF38A PRPF38A UHRF1BP1 UHRF1BP1 PRPF40A PRPF40A SNRNP70 SNRNP70 SF3A3 SF3A3 SNW1 SNW1 LSM7 LSM7 ENSRROP00000020651 ENSRROP00000020651 SF3A2 SF3A2 ENSRROP00000021355 ENSRROP00000021355 SNRPD2 SNRPD2 TFIP11 TFIP11 SRRM3 SRRM3 SNRPN SNRPN DHX8 DHX8 SNRPB SNRPB BUD31 BUD31 SF3B5 SF3B5 ENSRROP00000026765 ENSRROP00000026765 CWC15 CWC15 CWC22 CWC22 PRPF39 PRPF39 SNRNP200 SNRNP200 PRPF40B PRPF40B MFAP1 MFAP1 PHF5A PHF5A SNIP1 SNIP1 LUC7L3 LUC7L3 CWC25 CWC25 ENSRROP00000032718 ENSRROP00000032718 CWC27 CWC27 CRNKL1 CRNKL1 PRPF18 PRPF18 ENSRROP00000034505 ENSRROP00000034505 XAB2 XAB2 PRPF6 PRPF6 SNRPC SNRPC LUC7L LUC7L EIF4A3 EIF4A3 GCFC2 GCFC2 EFTUD2 EFTUD2 AQR AQR WBP4 WBP4 FMC1-LUC7L2 FMC1-LUC7L2 SF3A1 SF3A1 PPIE PPIE SART1 SART1 PPIL1 PPIL1 ENSRROP00000044639 ENSRROP00000044639 SNRPG SNRPG RNF113B RNF113B
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splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
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empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
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textmining
co-expression
protein homology
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SNRPG-2Small nuclear ribonucleoprotein G; Plays role in pre-mRNA splicing as core component of the SMN- Sm complex that mediates spliceosomal snRNP assembly and as component of the spliceosomal U1, U2, U4 and U5 small nuclear ribonucleoproteins (snRNPs), the building blocks of the spliceosome. Component of both the pre-catalytic spliceosome B complex and activated spliceosome C complexes. Is also a component of the minor U12 spliceosome. As part of the U7 snRNP it is involved in histone 3'-end processing. (74 aa)
RNF113ARing finger protein 113A. (343 aa)
YJU2YJU2 splicing factor homolog. (323 aa)
LOC104657389Sm domain-containing protein. (86 aa)
SNRPD1Small nuclear ribonucleoprotein Sm D1; Plays role in pre-mRNA splicing as core component of the SMN- Sm complex that mediates spliceosomal snRNP assembly and as component of the spliceosomal U1, U2, U4 and U5 small nuclear ribonucleoproteins (snRNPs), the building blocks of the spliceosome. Component of both the pre-catalytic spliceosome B complex and activated spliceosome C complexes. Is also a component of the minor U12 spliceosome. May act as a charged protein scaffold to promote snRNP assembly or strengthen snRNP-snRNP interactions through non-specific electrostatic contacts with RNA. (130 aa)
SNRNP40Small nuclear ribonucleoprotein U5 subunit 40. (357 aa)
CDC40Cell division cycle 40. (579 aa)
ENSRROP00000010290Small nuclear ribonucleoprotein G; Plays role in pre-mRNA splicing as core component of the SMN- Sm complex that mediates spliceosomal snRNP assembly and as component of the spliceosomal U1, U2, U4 and U5 small nuclear ribonucleoproteins (snRNPs), the building blocks of the spliceosome. Component of both the pre-catalytic spliceosome B complex and activated spliceosome C complexes. Is also a component of the minor U12 spliceosome. As part of the U7 snRNP it is involved in histone 3'-end processing. (66 aa)
ENSRROP00000010844SEC63 domain-containing protein. (325 aa)
IKIK cytokine. (585 aa)
LOC104672089Small nuclear ribonucleoprotein Sm D2; Plays role in pre-mRNA splicing as core component of the SMN- Sm complex that mediates spliceosomal snRNP assembly and as component of the spliceosomal U1, U2, U4 and U5 small nuclear ribonucleoproteins (snRNPs), the building blocks of the spliceosome. Component of both the pre-catalytic spliceosome B complex and activated spliceosome C complexes. Is also a component of the minor U12 spliceosome. (109 aa)
SRRM2Serine/arginine repetitive matrix 2. (2752 aa)
ENSRROP00000013502WD_REPEATS_REGION domain-containing protein. (354 aa)
SNRPFSm domain-containing protein. (127 aa)
U2AF2U2 snRNP auxiliary factor large subunit; Necessary for the splicing of pre-mRNA. Belongs to the splicing factor SR family. (414 aa)
SNRPD3Small nuclear ribonucleoprotein Sm D3; Plays role in pre-mRNA splicing as core component of the SMN- Sm complex that mediates spliceosomal snRNP assembly and as component of the spliceosomal U1, U2, U4 and U5 small nuclear ribonucleoproteins (snRNPs), the building blocks of the spliceosome. Component of both the pre-catalytic spliceosome B complex and activated spliceosome C complexes. Is also a component of the minor U12 spliceosome. As part of the U7 snRNP it is involved in histone pre-mRNA 3'-end processing. (126 aa)
LOC104669438U2 snRNP auxiliary factor large subunit; Necessary for the splicing of pre-mRNA. Belongs to the splicing factor SR family. (461 aa)
SNRPB2Small nuclear ribonucleoprotein polypeptide B2. (225 aa)
EFL1Elongation factor like GTPase 1. (1093 aa)
DHX16DEAH-box helicase 16. (1044 aa)
ENSRROP00000015661Tr-type G domain-containing protein. (92 aa)
ENSRROP00000016405Uncharacterized protein. (413 aa)
ZMAT2Zinc finger matrin-type 2. (199 aa)
PRPF38APRP38_assoc domain-containing protein. (312 aa)
UHRF1BP1UHRF1 binding protein 1. (1441 aa)
PRPF40APre-mRNA processing factor 40 homolog A. (930 aa)
SNRNP70Small nuclear ribonucleoprotein U1 subunit 70. (437 aa)
SF3A3Splicing factor 3a subunit 3. (504 aa)
SNW1SNW domain containing 1. (536 aa)
LSM7LSM7 homolog, U6 small nuclear RNA and mRNA degradation associated. (103 aa)
ENSRROP00000020651Small nuclear ribonucleoprotein G; Plays role in pre-mRNA splicing as core component of the SMN- Sm complex that mediates spliceosomal snRNP assembly and as component of the spliceosomal U1, U2, U4 and U5 small nuclear ribonucleoproteins (snRNPs), the building blocks of the spliceosome. Component of both the pre-catalytic spliceosome B complex and activated spliceosome C complexes. Is also a component of the minor U12 spliceosome. As part of the U7 snRNP it is involved in histone 3'-end processing. (67 aa)
SF3A2Splicing factor 3a subunit 2. (470 aa)
ENSRROP00000021355Uncharacterized protein. (254 aa)
SNRPD2Small nuclear ribonucleoprotein Sm D2; Plays role in pre-mRNA splicing as core component of the SMN- Sm complex that mediates spliceosomal snRNP assembly and as component of the spliceosomal U1, U2, U4 and U5 small nuclear ribonucleoproteins (snRNPs), the building blocks of the spliceosome. Component of both the pre-catalytic spliceosome B complex and activated spliceosome C complexes. Is also a component of the minor U12 spliceosome. (118 aa)
TFIP11Tuftelin-interacting protein 11; Involved in pre-mRNA splicing, specifically in spliceosome disassembly during late-stage splicing events. Intron turnover seems to proceed through reactions in two lariat-intron associated complexes termed Intron Large (IL) and Intron Small (IS). In cooperation with DHX15 seems to mediate the transition of the U2, U5 and U6 snRNP- containing IL complex to the snRNP-free IS complex leading to efficient debranching and turnover of excised introns. May play a role in the differentiation of ameloblasts and odontoblasts or in the forming of the enamel extrac [...] (837 aa)
SRRM3Serine/arginine repetitive matrix 3. (545 aa)
SNRPNSmall nuclear ribonucleoprotein-associated protein. (244 aa)
DHX8DEAH-box helicase 8. (1220 aa)
SNRPBSmall nuclear ribonucleoprotein-associated protein. (240 aa)
BUD31BUD31 homolog. (144 aa)
SF3B5Splicing factor 3B subunit 5; Belongs to the SF3B5 family. (86 aa)
ENSRROP00000026765Small nuclear ribonucleoprotein G; Plays role in pre-mRNA splicing as core component of the SMN- Sm complex that mediates spliceosomal snRNP assembly and as component of the spliceosomal U1, U2, U4 and U5 small nuclear ribonucleoproteins (snRNPs), the building blocks of the spliceosome. Component of both the pre-catalytic spliceosome B complex and activated spliceosome C complexes. Is also a component of the minor U12 spliceosome. As part of the U7 snRNP it is involved in histone 3'-end processing. (74 aa)
CWC15CWC15 spliceosome associated protein homolog. (229 aa)
CWC22CWC22 spliceosome associated protein homolog. (907 aa)
PRPF39Pre-mRNA processing factor 39. (669 aa)
SNRNP200Small nuclear ribonucleoprotein U5 subunit 200. (2146 aa)
PRPF40BPre-mRNA processing factor 40 homolog B. (892 aa)
MFAP1Microfibril associated protein 1. (439 aa)
PHF5APHD finger protein 5A. (110 aa)
SNIP1Smad nuclear interacting protein 1. (396 aa)
LUC7L3LUC7 like 3 pre-mRNA splicing factor. (480 aa)
CWC25CWC25 spliceosome associated protein homolog. (425 aa)
ENSRROP00000032718Uncharacterized protein. (286 aa)
CWC27CWC27 spliceosome associated cyclophilin. (473 aa)
CRNKL1Crooked neck pre-mRNA splicing factor 1. (687 aa)
PRPF18Pre-mRNA processing factor 18. (351 aa)
ENSRROP00000034505RRM domain-containing protein. (194 aa)
XAB2XPA binding protein 2. (860 aa)
PRPF6Pre-mRNA processing factor 6. (940 aa)
SNRPCU1 small nuclear ribonucleoprotein C; Component of the spliceosomal U1 snRNP, which is essential for recognition of the pre-mRNA 5' splice-site and the subsequent assembly of the spliceosome. SNRPC/U1-C is directly involved in initial 5' splice-site recognition for both constitutive and regulated alternative splicing. The interaction with the 5' splice-site seems to precede base-pairing between the pre-mRNA and the U1 snRNA. Stimulates commitment or early (E) complex formation by stabilizing the base pairing of the 5' end of the U1 snRNA and the 5' splice-site region. Belongs to the U1 [...] (180 aa)
LUC7LLUC7 like. (361 aa)
EIF4A3Eukaryotic translation initiation factor 4A3; Belongs to the DEAD box helicase family. (411 aa)
GCFC2GC-rich sequence DNA-binding factor 2. (788 aa)
EFTUD2Elongation factor Tu GTP binding domain containing 2. (972 aa)
AQRRNA helicase aquarius; Intron-binding spliceosomal protein required to link pre-mRNA splicing and snoRNP (small nucleolar ribonucleoprotein) biogenesis. Plays a key role in position-dependent assembly of intron-encoded box C/D small snoRNP, splicing being required for snoRNP assembly. May act by helping the folding of the snoRNA sequence. Binds to intron of pre- mRNAs in a sequence-independent manner, contacting the region between snoRNA and the branchpoint of introns (40 nucleotides upstream of the branchpoint) during the late stages of splicing. (1492 aa)
WBP4WW domain binding protein 4. (375 aa)
FMC1-LUC7L2FMC1-LUC7L2 readthrough. (448 aa)
SF3A1Splicing factor 3a subunit 1. (793 aa)
PPIEPeptidyl-prolyl cis-trans isomerase E; Catalyzes the cis-trans isomerization of proline imidic peptide bonds in proteins; Belongs to the cyclophilin-type PPIase family. PPIase E subfamily. (320 aa)
SART1Spliceosome associated factor 1, recruiter of U4/U6.U5 tri-snRNP. (800 aa)
PPIL1Peptidyl-prolyl cis-trans isomerase; PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides; Belongs to the cyclophilin-type PPIase family. (166 aa)
ENSRROP00000044639Small nuclear ribonucleoprotein G; Plays role in pre-mRNA splicing as core component of the SMN- Sm complex that mediates spliceosomal snRNP assembly and as component of the spliceosomal U1, U2, U4 and U5 small nuclear ribonucleoproteins (snRNPs), the building blocks of the spliceosome. Component of both the pre-catalytic spliceosome B complex and activated spliceosome C complexes. Is also a component of the minor U12 spliceosome. As part of the U7 snRNP it is involved in histone 3'-end processing. (72 aa)
SNRPGSmall nuclear ribonucleoprotein G; Plays role in pre-mRNA splicing as core component of the SMN- Sm complex that mediates spliceosomal snRNP assembly and as component of the spliceosomal U1, U2, U4 and U5 small nuclear ribonucleoproteins (snRNPs), the building blocks of the spliceosome. Component of both the pre-catalytic spliceosome B complex and activated spliceosome C complexes. Is also a component of the minor U12 spliceosome. As part of the U7 snRNP it is involved in histone 3'-end processing. (76 aa)
RNF113BRing finger protein 113B. (322 aa)
Your Current Organism:
Rhinopithecus roxellana
NCBI taxonomy Id: 61622
Other names: Pygathrix roxellana, R. roxellana, golden snub-nosed monkey
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