(52 nodes) SCF ubiquitin ligase complex network (Rhinopithecus roxellana)

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	FBXL15	F-box and leucine rich repeat protein 15. (300 aa)
	FLI1	Fli-1 proto-oncogene, ETS transcription factor. (453 aa)
	FBXL17	F-box and leucine rich repeat protein 17. (471 aa)
	FBXL21P	F-box domain-containing protein. (434 aa)
	FBXW11	F-box and WD repeat domain containing 11. (542 aa)
	FBXL5	F-box and leucine rich repeat protein 5. (691 aa)
	NCBP3	Nuclear cap binding subunit 3. (630 aa)
	SKP1	S-phase kinase associated protein 1; Belongs to the SKP1 family. (163 aa)
	CCNF	Cyclin F; Belongs to the cyclin family. (786 aa)
	FBXO4	F-box protein 4. (387 aa)
	FBXW7	F-box and WD repeat domain containing 7. (707 aa)
	FBXO33	F-box protein 33. (557 aa)
	LRRC29	Leucine rich repeat containing 29. (214 aa)
	FBXL22	F-box and leucine rich repeat protein 22. (231 aa)
	FBXO45	F-box protein 45. (359 aa)
	LOC104677263	Uncharacterized protein; Belongs to the SKP1 family. (155 aa)
	ENSRROP00000000820	Cyclin-dependent kinases regulatory subunit; Binds to the catalytic subunit of the cyclin dependent kinases and is essential for their biological function. (77 aa)
	CKS1B	Cyclin-dependent kinases regulatory subunit; Binds to the catalytic subunit of the cyclin dependent kinases and is essential for their biological function. (79 aa)
	FBXL19	F-box and leucine rich repeat protein 19. (694 aa)
	FBXL14	F-box and leucine rich repeat protein 14. (418 aa)
	FBXO25	F-box protein 25. (367 aa)
	FBXL7	F-box and leucine rich repeat protein 7. (488 aa)
	ENSRROP00000004412	Uncharacterized protein. (427 aa)
	LOC104660852	Cyclin-dependent kinases regulatory subunit 1. (79 aa)
	FBXO17	F-box protein 17. (278 aa)
	FBXO42	F-box protein 42. (716 aa)
	FBXO31	F-box protein 31. (464 aa)
	FBXO27	F-box protein 27. (283 aa)
	FBXO38	F-box protein 38. (1188 aa)
	RBX1	Ring-box 1. (108 aa)
	FBH1	F-box DNA helicase 1. (1079 aa)
	FBXO9	F-box protein 9. (437 aa)
	FBXW5	F-box and WD repeat domain containing 5. (566 aa)
	ENSRROP00000010804	Uncharacterized protein. (331 aa)
	USP47	Ubiquitin specific peptidase 47; Belongs to the peptidase C19 family. (1375 aa)
	CUL1	Cullin 1; Belongs to the cullin family. (776 aa)
	FBXL12	F-box and leucine rich repeat protein 12. (326 aa)
	BTRC	Beta-transducin repeat containing E3 ubiquitin protein ligase. (605 aa)
	ENSRROP00000022934	Uncharacterized protein. (336 aa)
	ENSRROP00000021577	Uncharacterized protein; Belongs to the SKP1 family. (129 aa)
	FBXO44	Uncharacterized protein. (255 aa)
	ZC3HC1	Zinc finger C3HC-type containing 1. (502 aa)
	FBXL2	F-box and leucine rich repeat protein 2. (425 aa)
	ENSRROP00000034976	Cyclin-dependent kinases regulatory subunit; Binds to the catalytic subunit of the cyclin dependent kinases and is essential for their biological function. (121 aa)
	FBXO32	F-box protein 32. (360 aa)
	SKP2	S-phase kinase associated protein 2. (424 aa)
	TMEM183A	Uncharacterized protein. (376 aa)
	FBXO41	F-box protein 41. (796 aa)
	CKS2	Cyclin-dependent kinases regulatory subunit; Binds to the catalytic subunit of the cyclin dependent kinases and is essential for their biological function. (79 aa)
	FBXL3	F-box and leucine rich repeat protein 3. (428 aa)
	ENSRROP00000029707	Cyclin-dependent kinases regulatory subunit; Binds to the catalytic subunit of the cyclin dependent kinases and is essential for their biological function. (64 aa)
	FBXO2	F-box protein 2. (423 aa)

Your Current Organism:

Rhinopithecus roxellana

NCBI taxonomy Id: 61622
Other names: Pygathrix roxellana, R. roxellana, golden snub-nosed monkey

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
BTRC	CCNF	ENSRROP00000012019	ENSRROP00000043538	Beta-transducin repeat containing E3 ubiquitin protein ligase.	Cyclin F; Belongs to the cyclin family.	0.593
BTRC	CUL1	ENSRROP00000012019	ENSRROP00000011177	Beta-transducin repeat containing E3 ubiquitin protein ligase.	Cullin 1; Belongs to the cullin family.	0.999
BTRC	ENSRROP00000004412	ENSRROP00000012019	ENSRROP00000004412	Beta-transducin repeat containing E3 ubiquitin protein ligase.	Uncharacterized protein.	0.666
BTRC	ENSRROP00000021577	ENSRROP00000012019	ENSRROP00000021577	Beta-transducin repeat containing E3 ubiquitin protein ligase.	Uncharacterized protein; Belongs to the SKP1 family.	0.911
BTRC	FBXO2	ENSRROP00000012019	ENSRROP00000029421	Beta-transducin repeat containing E3 ubiquitin protein ligase.	F-box protein 2.	0.944
BTRC	FBXO4	ENSRROP00000012019	ENSRROP00000043894	Beta-transducin repeat containing E3 ubiquitin protein ligase.	F-box protein 4.	0.916
BTRC	FBXW11	ENSRROP00000012019	ENSRROP00000038539	Beta-transducin repeat containing E3 ubiquitin protein ligase.	F-box and WD repeat domain containing 11.	0.663
BTRC	FBXW7	ENSRROP00000012019	ENSRROP00000045098	Beta-transducin repeat containing E3 ubiquitin protein ligase.	F-box and WD repeat domain containing 7.	0.953
BTRC	LOC104677263	ENSRROP00000012019	ENSRROP00000000226	Beta-transducin repeat containing E3 ubiquitin protein ligase.	Uncharacterized protein; Belongs to the SKP1 family.	0.994
BTRC	RBX1	ENSRROP00000012019	ENSRROP00000009431	Beta-transducin repeat containing E3 ubiquitin protein ligase.	Ring-box 1.	0.997
BTRC	SKP1	ENSRROP00000012019	ENSRROP00000042381	Beta-transducin repeat containing E3 ubiquitin protein ligase.	S-phase kinase associated protein 1; Belongs to the SKP1 family.	0.994
BTRC	SKP2	ENSRROP00000012019	ENSRROP00000033413	Beta-transducin repeat containing E3 ubiquitin protein ligase.	S-phase kinase associated protein 2.	0.967
BTRC	USP47	ENSRROP00000012019	ENSRROP00000011012	Beta-transducin repeat containing E3 ubiquitin protein ligase.	Ubiquitin specific peptidase 47; Belongs to the peptidase C19 family.	0.594
CCNF	BTRC	ENSRROP00000043538	ENSRROP00000012019	Cyclin F; Belongs to the cyclin family.	Beta-transducin repeat containing E3 ubiquitin protein ligase.	0.593
CCNF	CKS1B	ENSRROP00000043538	ENSRROP00000000931	Cyclin F; Belongs to the cyclin family.	Cyclin-dependent kinases regulatory subunit; Binds to the catalytic subunit of the cyclin dependent kinases and is essential for their biological function.	0.568
CCNF	CKS2	ENSRROP00000043538	ENSRROP00000032556	Cyclin F; Belongs to the cyclin family.	Cyclin-dependent kinases regulatory subunit; Binds to the catalytic subunit of the cyclin dependent kinases and is essential for their biological function.	0.568
CCNF	CUL1	ENSRROP00000043538	ENSRROP00000011177	Cyclin F; Belongs to the cyclin family.	Cullin 1; Belongs to the cullin family.	0.931
CCNF	ENSRROP00000000820	ENSRROP00000043538	ENSRROP00000000820	Cyclin F; Belongs to the cyclin family.	Cyclin-dependent kinases regulatory subunit; Binds to the catalytic subunit of the cyclin dependent kinases and is essential for their biological function.	0.568
CCNF	ENSRROP00000021577	ENSRROP00000043538	ENSRROP00000021577	Cyclin F; Belongs to the cyclin family.	Uncharacterized protein; Belongs to the SKP1 family.	0.806
CCNF	ENSRROP00000029707	ENSRROP00000043538	ENSRROP00000029707	Cyclin F; Belongs to the cyclin family.	Cyclin-dependent kinases regulatory subunit; Binds to the catalytic subunit of the cyclin dependent kinases and is essential for their biological function.	0.568