(20 nodes) TGF-beta, propeptide network (Rhinopithecus roxellana)

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	INHBA	Inhibin subunit beta A. (492 aa)
	BMP4	Bone morphogenetic protein 4. (408 aa)
	GDF11	Growth differentiation factor 11. (344 aa)
	TGFB2	Transforming growth factor beta; Belongs to the TGF-beta family. (442 aa)
	INHBB	Inhibin subunit beta B. (396 aa)
	BMP10	Bone morphogenetic protein 10. (424 aa)
	LEFTY1	Left-right determination factor. (366 aa)
	BMP3	Bone morphogenetic protein 3; Belongs to the TGF-beta family. (472 aa)
	BMP8B	TGF_BETA_2 domain-containing protein. (402 aa)
	GDF7	Growth differentiation factor 7. (450 aa)
	BMP5	Bone morphogenetic protein 5. (454 aa)
	MSTN	Myostatin. (376 aa)
	TGFB3	Transforming growth factor beta; Belongs to the TGF-beta family. (412 aa)
	BMP7	Bone morphogenetic protein 7. (431 aa)
	GDF2	Growth differentiation factor 2. (429 aa)
	GDF5	Growth differentiation factor 5. (499 aa)
	GDF6	Growth differentiation factor 6. (405 aa)
	BMP2	Bone morphogenetic protein 2. (470 aa)
	BMP6	Bone morphogenetic protein 6. (439 aa)
	TGFB1	Transforming growth factor beta; Belongs to the TGF-beta family. (391 aa)

Your Current Organism:

Rhinopithecus roxellana

NCBI taxonomy Id: 61622
Other names: Pygathrix roxellana, R. roxellana, golden snub-nosed monkey

Send network to Cytoscape

Export your current network:

... as a bitmap image:

download

file format is 'PNG': portable network graphic

... as a high-resolution bitmap:

download

same PNG format, but at higher resolution

... as a vector graphic:

download

SVG: scalable vector graphic - can be opened and edited in Illustrator, CorelDraw, Dia, etc

... as short tabular text output:

download

TSV: tab separated values - can be opened in Excel and Cytoscape (lists only one-way edges: A-B)

... as tabular text output:

download

TSV: tab separated values - can be opened in Excel (lists reciprocal edges: A-B,B-A)

... as an XML summary:

download

structured XML interaction data, according to the 'PSI-MI' data standard

... protein node degrees:

download

node degree of proteins in your network (given the current score cut-off)

... network coordinates:

download

a flat-file format describing the coordinates and colors of nodes in the network

... protein sequences:

download

MFA: multi-fasta format - containing the aminoacid sequences in the network

... protein annotations:

download

a tab-delimited file describing the names, domains and descriptions of proteins in your network

... functional annotations:

download

a tab-delimited file containing all known functional terms of proteins in your network

Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
BMP10	GDF2	ENSRROP00000032265	ENSRROP00000004023	Bone morphogenetic protein 10.	Growth differentiation factor 2.	0.716
BMP2	BMP4	ENSRROP00000011353	ENSRROP00000036929	Bone morphogenetic protein 2.	Bone morphogenetic protein 4.	0.940
BMP2	BMP5	ENSRROP00000011353	ENSRROP00000045029	Bone morphogenetic protein 2.	Bone morphogenetic protein 5.	0.606
BMP2	BMP6	ENSRROP00000011353	ENSRROP00000016342	Bone morphogenetic protein 2.	Bone morphogenetic protein 6.	0.960
BMP2	BMP7	ENSRROP00000011353	ENSRROP00000002092	Bone morphogenetic protein 2.	Bone morphogenetic protein 7.	0.826
BMP2	GDF5	ENSRROP00000011353	ENSRROP00000004188	Bone morphogenetic protein 2.	Growth differentiation factor 5.	0.613
BMP4	BMP2	ENSRROP00000036929	ENSRROP00000011353	Bone morphogenetic protein 4.	Bone morphogenetic protein 2.	0.940
BMP4	BMP5	ENSRROP00000036929	ENSRROP00000045029	Bone morphogenetic protein 4.	Bone morphogenetic protein 5.	0.606
BMP4	BMP6	ENSRROP00000036929	ENSRROP00000016342	Bone morphogenetic protein 4.	Bone morphogenetic protein 6.	0.960
BMP4	BMP7	ENSRROP00000036929	ENSRROP00000002092	Bone morphogenetic protein 4.	Bone morphogenetic protein 7.	0.790
BMP4	GDF5	ENSRROP00000036929	ENSRROP00000004188	Bone morphogenetic protein 4.	Growth differentiation factor 5.	0.465
BMP5	BMP2	ENSRROP00000045029	ENSRROP00000011353	Bone morphogenetic protein 5.	Bone morphogenetic protein 2.	0.606
BMP5	BMP4	ENSRROP00000045029	ENSRROP00000036929	Bone morphogenetic protein 5.	Bone morphogenetic protein 4.	0.606
BMP5	GDF7	ENSRROP00000045029	ENSRROP00000016093	Bone morphogenetic protein 5.	Growth differentiation factor 7.	0.562
BMP6	BMP2	ENSRROP00000016342	ENSRROP00000011353	Bone morphogenetic protein 6.	Bone morphogenetic protein 2.	0.960
BMP6	BMP4	ENSRROP00000016342	ENSRROP00000036929	Bone morphogenetic protein 6.	Bone morphogenetic protein 4.	0.960
BMP6	GDF7	ENSRROP00000016342	ENSRROP00000016093	Bone morphogenetic protein 6.	Growth differentiation factor 7.	0.562
BMP7	BMP2	ENSRROP00000002092	ENSRROP00000011353	Bone morphogenetic protein 7.	Bone morphogenetic protein 2.	0.826
BMP7	BMP4	ENSRROP00000002092	ENSRROP00000036929	Bone morphogenetic protein 7.	Bone morphogenetic protein 4.	0.790
BMP7	GDF5	ENSRROP00000002092	ENSRROP00000004188	Bone morphogenetic protein 7.	Growth differentiation factor 5.	0.415