STRINGSTRING
SH2D4A SH2D4A SH2D5 SH2D5 BMX BMX PTPN6 PTPN6 LCP2 LCP2 ITK ITK SOCS7 SOCS7 PLCG1 PLCG1 DAPP1 DAPP1 SH2D1A SH2D1A SUPT6H SUPT6H CRK CRK VAV3 VAV3 RASA1 RASA1 PIK3R1 PIK3R1 ENSRROP00000021422 ENSRROP00000021422 TEC TEC SYK SYK SRC SRC BTK BTK SLA2 SLA2 SH2D2A SH2D2A GRAP GRAP FYN FYN STAT3 STAT3 YES1 YES1 STAT6 STAT6 ABL1 ABL1 SHC1 SHC1 PTPN11 PTPN11 SH2D7 SH2D7 CISH CISH STAP2 STAP2 VAV2 VAV2 STAT2 STAT2 LCK LCK VAV1 VAV1 RIN3 RIN3 TYK2 TYK2 INPPL1 INPPL1 STAT5B STAT5B INPP5D INPP5D BLNK BLNK JAK2 JAK2 ENSRROP00000010437 ENSRROP00000010437 GRB7 GRB7 SH2B3 SH2B3 SH2B1 SH2B1 SH2D6 SH2D6 TNS1 TNS1 SHC4 SHC4 SHF SHF SH2D1B SH2D1B RIN2 RIN2 NCK2 NCK2 FRK FRK STAT5A STAT5A SOCS1 SOCS1 PTK6 PTK6 SHC3 SHC3 HSH2D HSH2D PIK3R2 PIK3R2 LYN LYN SOCS3 SOCS3 SH3BP2 SH3BP2 FER FER ENSRROP00000004714 ENSRROP00000004714 ABL2 ABL2 SLA SLA PLCG2 PLCG2 STAT4 STAT4 CBLC CBLC SOCS2 SOCS2 CLNK CLNK TNS3 TNS3 NCK1 NCK1 RIN1 RIN1 GRAP2 GRAP2 TXK TXK SH2D3C SH2D3C HCK HCK CBLB CBLB JAK1 JAK1 CRKL CRKL STAP1 STAP1 TNS4 TNS4 CSK CSK RINL RINL GRB14 GRB14 ENSRROP00000036200 ENSRROP00000036200 FES FES SHB SHB ZAP70 ZAP70 ENSRROP00000034614 ENSRROP00000034614 SH2D3A SH2D3A TNS2 TNS2 GRB2 GRB2 BLK BLK SHE SHE STAT1 STAT1 CHN2 CHN2 FGR FGR GRB10 GRB10 BCAR3 BCAR3 CBL CBL PIK3R3 PIK3R3 JAK3 JAK3 SRMS SRMS SHD SHD SOCS4 SOCS4 SOCS6 SOCS6 SOCS5 SOCS5 SH2B2 SH2B2 MATK MATK
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
SH2D4ASH2 domain containing 4A. (454 aa)
SH2D5SH2 domain containing 5. (427 aa)
BMXTyrosine-protein kinase. (675 aa)
PTPN6Tyrosine-protein phosphatase non-receptor type; Belongs to the protein-tyrosine phosphatase family. Non- receptor class 2 subfamily. (623 aa)
LCP2Lymphocyte cytosolic protein 2. (533 aa)
ITKTyrosine-protein kinase. (620 aa)
SOCS7Suppressor of cytokine signaling 7. (584 aa)
PLCG11-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma; Mediates the production of the second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3). Plays an important role in the regulation of intracellular signaling cascades. (1303 aa)
DAPP1Dual adaptor of phosphotyrosine and 3-phosphoinositides 1. (280 aa)
SH2D1ASH2 domain-containing protein 1A; Cytoplasmic adapter regulating receptors of the signaling lymphocytic activation molecule (SLAM) family such as SLAMF1, CD244, LY9, CD84, SLAMF6 and SLAMF7. In SLAM signaling seems to cooperate with SH2D1B/EAT-2. (128 aa)
SUPT6HTranscription elongation factor spt6; Transcription elongation factor that enhances transcription elongation by RNA polymerase II (RNAPII). Belongs to the SPT6 family. (1726 aa)
CRKCRK proto-oncogene, adaptor protein. (304 aa)
VAV3Uncharacterized protein. (287 aa)
RASA1RAS p21 protein activator 1. (1047 aa)
PIK3R1Phosphoinositide-3-kinase regulatory subunit 1. (724 aa)
ENSRROP00000021422Uncharacterized protein. (534 aa)
TECTyrosine-protein kinase. (630 aa)
SYKTyrosine-protein kinase. (635 aa)
SRCTyrosine-protein kinase. (540 aa)
BTKTyrosine-protein kinase. (690 aa)
SLA2Src like adaptor 2. (261 aa)
SH2D2ASH2 domain containing 2A. (389 aa)
GRAPGRB2 related adaptor protein. (217 aa)
FYNTyrosine-protein kinase. (537 aa)
STAT3Signal transducer and activator of transcription. (802 aa)
YES1Tyrosine-protein kinase. (543 aa)
STAT6Signal transducer and activator of transcription. (847 aa)
ABL1Tyrosine-protein kinase. (1149 aa)
SHC1SHC adaptor protein 1. (574 aa)
PTPN11Tyrosine-protein phosphatase non-receptor type; Belongs to the protein-tyrosine phosphatase family. Non- receptor class 2 subfamily. (593 aa)
SH2D7SH2 domain containing 7. (456 aa)
CISHCytokine inducible SH2 containing protein. (275 aa)
STAP2Signal transducing adaptor family member 2. (514 aa)
VAV2Vav guanine nucleotide exchange factor 2. (810 aa)
STAT2Signal transducer and activator of transcription. (859 aa)
LCKTyrosine-protein kinase. (561 aa)
VAV1Vav guanine nucleotide exchange factor 1. (845 aa)
RIN3Ras and Rab interactor 3. (1001 aa)
TYK2Tyrosine-protein kinase. (1187 aa)
INPPL1Inositol polyphosphate phosphatase like 1. (1302 aa)
STAT5BSignal transducer and activator of transcription. (787 aa)
INPP5DInositol polyphosphate-5-phosphatase D. (1188 aa)
BLNKB cell linker. (456 aa)
JAK2Tyrosine-protein kinase. (1094 aa)
ENSRROP00000010437Uncharacterized protein. (235 aa)
GRB7Growth factor receptor bound protein 7. (558 aa)
SH2B3SH2B adaptor protein 3. (596 aa)
SH2B1SH2B adaptor protein 1. (756 aa)
SH2D6SH2 domain-containing protein. (168 aa)
TNS1Tensin 1. (1878 aa)
SHC4SHC adaptor protein 4. (630 aa)
SHFSrc homology 2 domain containing F. (421 aa)
SH2D1BSH2 domain containing 1B. (132 aa)
RIN2Ras and Rab interactor 2. (862 aa)
NCK2Cytoplasmic protein. (382 aa)
FRKTyrosine-protein kinase. (505 aa)
STAT5ASignal transducer and activator of transcription. (905 aa)
SOCS1Suppressor of cytokine signaling 1. (215 aa)
PTK6Tyrosine-protein kinase. (451 aa)
SHC3SHC adaptor protein 3. (546 aa)
HSH2DHematopoietic SH2 domain containing. (352 aa)
PIK3R2Uncharacterized protein. (647 aa)
LYNTyrosine-protein kinase. (491 aa)
SOCS3Suppressor of cytokine signaling 3. (225 aa)
SH3BP2SH3 domain binding protein 2. (589 aa)
FERTyrosine-protein kinase; Belongs to the protein kinase superfamily. Tyr protein kinase family. Fes/fps subfamily. (822 aa)
ENSRROP00000004714SOCS box domain-containing protein. (476 aa)
ABL2Tyrosine-protein kinase. (1164 aa)
SLASrc like adaptor. (293 aa)
PLCG21-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma; Mediates the production of the second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3). Plays an important role in the regulation of intracellular signaling cascades. (1265 aa)
STAT4Signal transducer and activator of transcription. (748 aa)
CBLCCbl proto-oncogene C. (527 aa)
SOCS2Suppressor of cytokine signaling 2. (198 aa)
CLNKCytokine dependent hematopoietic cell linker. (428 aa)
TNS3Tensin 3. (1559 aa)
NCK1Cytoplasmic protein. (377 aa)
RIN1Ras and Rab interactor 1. (783 aa)
GRAP2GRB2 related adaptor protein 2. (330 aa)
TXKTyrosine-protein kinase. (527 aa)
SH2D3CSH2 domain containing 3C. (860 aa)
HCKTyrosine-protein kinase. (591 aa)
CBLBCbl proto-oncogene B. (982 aa)
JAK1Tyrosine-protein kinase. (1154 aa)
CRKLCRK like proto-oncogene, adaptor protein. (303 aa)
STAP1Signal transducing adaptor family member 1. (295 aa)
TNS4Tensin 4. (754 aa)
CSKTyrosine-protein kinase. (450 aa)
RINLRas and Rab interactor like. (562 aa)
GRB14Growth factor receptor bound protein 14. (540 aa)
ENSRROP00000036200Uncharacterized protein. (491 aa)
FESTyrosine-protein kinase; Belongs to the protein kinase superfamily. Tyr protein kinase family. Fes/fps subfamily. (822 aa)
SHBSH2 domain containing adaptor protein B. (509 aa)
ZAP70Tyrosine-protein kinase. (619 aa)
ENSRROP00000034614Tyrosine-protein kinase. (465 aa)
SH2D3ASH2 domain containing 3A. (582 aa)
TNS2Tensin 2. (1361 aa)
GRB2Growth factor receptor bound protein 2. (217 aa)
BLKTyrosine-protein kinase. (505 aa)
SHESrc homology 2 domain containing E. (520 aa)
STAT1Signal transducer and activator of transcription. (787 aa)
CHN2Chimaerin; GTPase-activating protein for p21-rac. (468 aa)
FGRTyrosine-protein kinase. (529 aa)
GRB10Growth factor receptor bound protein 10. (593 aa)
BCAR3BCAR3 adaptor protein, NSP family member. (825 aa)
CBLCbl proto-oncogene. (906 aa)
PIK3R3Phosphoinositide-3-kinase regulatory subunit 3. (461 aa)
JAK3Tyrosine-protein kinase. (1124 aa)
SRMSTyrosine-protein kinase. (492 aa)
SHDSrc homology 2 domain containing transforming protein D. (340 aa)
SOCS4Suppressor of cytokine signaling 4. (439 aa)
SOCS6Suppressor of cytokine signaling 6. (535 aa)
SOCS5Suppressor of cytokine signaling 5. (536 aa)
SH2B2SH2B adaptor protein 2. (645 aa)
MATKTyrosine-protein kinase. (554 aa)
Your Current Organism:
Rhinopithecus roxellana
NCBI taxonomy Id: 61622
Other names: Pygathrix roxellana, R. roxellana, golden snub-nosed monkey
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