(4 nodes) JAK, FERM F2 lobe domain network (Rhinopithecus roxellana)

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	JAK1	Tyrosine-protein kinase. (1154 aa)
	TYK2	Tyrosine-protein kinase. (1187 aa)
	JAK2	Tyrosine-protein kinase. (1094 aa)
	JAK3	Tyrosine-protein kinase. (1124 aa)

Your Current Organism:

Rhinopithecus roxellana

NCBI taxonomy Id: 61622
Other names: Pygathrix roxellana, R. roxellana, golden snub-nosed monkey

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
JAK1	JAK2	ENSRROP00000040577	ENSRROP00000011033	Tyrosine-protein kinase.	Tyrosine-protein kinase.	0.990
JAK1	JAK3	ENSRROP00000040577	ENSRROP00000004608	Tyrosine-protein kinase.	Tyrosine-protein kinase.	0.990
JAK1	TYK2	ENSRROP00000040577	ENSRROP00000013030	Tyrosine-protein kinase.	Tyrosine-protein kinase.	0.979
JAK2	JAK1	ENSRROP00000011033	ENSRROP00000040577	Tyrosine-protein kinase.	Tyrosine-protein kinase.	0.990
JAK2	JAK3	ENSRROP00000011033	ENSRROP00000004608	Tyrosine-protein kinase.	Tyrosine-protein kinase.	0.952
JAK2	TYK2	ENSRROP00000011033	ENSRROP00000013030	Tyrosine-protein kinase.	Tyrosine-protein kinase.	0.980
JAK3	JAK1	ENSRROP00000004608	ENSRROP00000040577	Tyrosine-protein kinase.	Tyrosine-protein kinase.	0.990
JAK3	JAK2	ENSRROP00000004608	ENSRROP00000011033	Tyrosine-protein kinase.	Tyrosine-protein kinase.	0.952
JAK3	TYK2	ENSRROP00000004608	ENSRROP00000013030	Tyrosine-protein kinase.	Tyrosine-protein kinase.	0.790
TYK2	JAK1	ENSRROP00000013030	ENSRROP00000040577	Tyrosine-protein kinase.	Tyrosine-protein kinase.	0.979
TYK2	JAK2	ENSRROP00000013030	ENSRROP00000011033	Tyrosine-protein kinase.	Tyrosine-protein kinase.	0.980
TYK2	JAK3	ENSRROP00000013030	ENSRROP00000004608	Tyrosine-protein kinase.	Tyrosine-protein kinase.	0.790