STRINGSTRING
CREB1 CREB1 PLCB1 PLCB1 ENSRROP00000022234 ENSRROP00000022234 PDE1A PDE1A KPNA2 KPNA2 THAP6 THAP6 ENSRROP00000019711 ENSRROP00000019711 CDK5 CDK5 PLCB3 PLCB3 GNAI1 GNAI1 NBEA NBEA PPP2R1B PPP2R1B GNAT3 GNAT3 PRKAR1B PRKAR1B GNAL GNAL CAMK2A CAMK2A GNAI3 GNAI3 GRK2 GRK2 PRKCG PRKCG GNA11 GNA11 PPP3CB PPP3CB GNB1 GNB1 CNBD2 CNBD2 PPP2CB PPP2CB PPP1R1B PPP1R1B PPP3R1 PPP3R1 ENSRROP00000013107 ENSRROP00000013107 PLA2G4A PLA2G4A ADCY2 ADCY2 ENSRROP00000011975 ENSRROP00000011975 PRKCD PRKCD PRKACA PRKACA GNG13 GNG13 PRKX PRKX PDE4A PDE4A PTRHD1 PTRHD1 GNAI2 GNAI2 ADCY1 ADCY1 GNG7 GNG7 ENSRROP00000007762 ENSRROP00000007762 ENSRROP00000007422 ENSRROP00000007422 PDE4D PDE4D ENSRROP00000006428 ENSRROP00000006428 ENSRROP00000006154 ENSRROP00000006154 GNB3 GNB3 PDE4B PDE4B PRKACB PRKACB ENSRROP00000005502 ENSRROP00000005502 GNGT2 GNGT2 DCLK1 DCLK1 PLCB2 PLCB2 ADCY5 ADCY5 GNG2 GNG2 CAMK4 CAMK4 ENSRROP00000003001 ENSRROP00000003001 ENSRROP00000002323 ENSRROP00000002323 GNGT1 GNGT1 ADCY4 ADCY4 ADCY8 ADCY8 CAMK2D CAMK2D ENSRROP00000045475 ENSRROP00000045475 PPP3CA PPP3CA POMC POMC GNG8 GNG8 CAMKK2 CAMKK2 ITPR1 ITPR1 PDE1C PDE1C LOC104677425 LOC104677425 PRKCA PRKCA GNG12 GNG12 ADCY3 ADCY3 ADCY6 ADCY6 GNB2 GNB2 PDYN PDYN ENSRROP00000038862 ENSRROP00000038862 GNG11 GNG11 CAMK2G CAMK2G PRKAR2A PRKAR2A OPRM1 OPRM1 ADCY7 ADCY7 PPP2R5D PPP2R5D GNB4 GNB4 PRKAR2B PRKAR2B ENSRROP00000035890 ENSRROP00000035890 ITPR3 ITPR3 GNAQ GNAQ GNG5 GNG5 PDE1B PDE1B CAMK2B CAMK2B NBEA-2 NBEA-2 ENSRROP00000034142 ENSRROP00000034142 THAP7 THAP7 GNG4 GNG4 PPP1CA PPP1CA LRBA LRBA GNB5 GNB5 PPP2R1A PPP2R1A ENSRROP00000029359 ENSRROP00000029359 CAMKK1 CAMKK1 GNG3 GNG3 PPP3CC PPP3CC GNA14 GNA14 ADCY9 ADCY9 PLCB4 PLCB4 AHCYL1 AHCYL1 PRKAR1A PRKAR1A PPP2CA PPP2CA MAPK1 MAPK1 PDE4C PDE4C GNA15 GNA15 ITPR2 ITPR2
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
CREB1cAMP responsive element binding protein 1. (341 aa)
PLCB11-phosphatidylinositol 4,5-bisphosphate phosphodiesterase; The production of the second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3) is mediated by activated phosphatidylinositol-specific phospholipase C enzymes. (1114 aa)
ENSRROP00000022234Guanine nucleotide-binding protein subunit gamma; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction. (59 aa)
PDE1APhosphodiesterase. (544 aa)
KPNA2IBB domain-containing protein. (114 aa)
THAP6THAP domain containing 6. (222 aa)
ENSRROP00000019711PDE4_UCR domain-containing protein. (158 aa)
CDK5Cyclin dependent kinase 5; Belongs to the protein kinase superfamily. (292 aa)
PLCB31-phosphatidylinositol 4,5-bisphosphate phosphodiesterase; The production of the second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3) is mediated by activated phosphatidylinositol-specific phospholipase C enzymes. (1234 aa)
GNAI1G protein subunit alpha i1. (253 aa)
NBEAUncharacterized protein. (630 aa)
PPP2R1BProtein phosphatase 2 scaffold subunit Abeta. (667 aa)
GNAT3Uncharacterized protein. (196 aa)
PRKAR1BProtein kinase cAMP-dependent type I regulatory subunit beta. (381 aa)
GNALG protein subunit alpha L. (448 aa)
CAMK2ACalcium/calmodulin dependent protein kinase II alpha; Belongs to the protein kinase superfamily. (489 aa)
GNAI3G protein subunit alpha i3. (354 aa)
GRK2G protein-coupled receptor kinase; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. GPRK subfamily. (726 aa)
PRKCGProtein kinase C; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. PKC subfamily. (697 aa)
GNA11G protein subunit alpha 11. (359 aa)
PPP3CBSerine/threonine-protein phosphatase. (521 aa)
GNB1G protein subunit beta 1. (340 aa)
CNBD2Cyclic nucleotide binding domain containing 2. (581 aa)
PPP2CBSerine/threonine-protein phosphatase. (312 aa)
PPP1R1BProtein phosphatase 1 regulatory inhibitor subunit 1B. (204 aa)
PPP3R1Uncharacterized protein. (189 aa)
ENSRROP00000013107Uncharacterized protein. (128 aa)
PLA2G4APhospholipase A2. (749 aa)
ADCY2Adenylate cyclase type 2; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling. (1052 aa)
ENSRROP00000011975Uncharacterized protein. (379 aa)
PRKCDProtein kinase C delta type; Calcium-independent, phospholipid- and diacylglycerol (DAG)- dependent serine/threonine-protein kinase that plays contrasting roles in cell death and cell survival by functioning as a pro-apoptotic protein during DNA damage-induced apoptosis, but acting as an anti- apoptotic protein during cytokine receptor-initiated cell death, is involved in tumor suppression; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. PKC subfamily. (676 aa)
PRKACAProtein kinase cAMP-activated catalytic subunit alpha; Belongs to the protein kinase superfamily. (351 aa)
GNG13G protein subunit gamma 13. (67 aa)
PRKXUncharacterized protein; Belongs to the protein kinase superfamily. (321 aa)
PDE4APhosphodiesterase. (886 aa)
PTRHD1Peptidyl-tRNA hydrolase domain containing 1. (140 aa)
GNAI2G protein subunit alpha i2. (355 aa)
ADCY1Adenylate cyclase type 1; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling. (1075 aa)
GNG7Guanine nucleotide-binding protein subunit gamma; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction. (68 aa)
ENSRROP00000007762Guanine nucleotide-binding protein subunit gamma; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction. (69 aa)
ENSRROP00000007422Uncharacterized protein. (187 aa)
PDE4DPhosphodiesterase. (585 aa)
ENSRROP00000006428Uncharacterized protein. (70 aa)
ENSRROP00000006154Uncharacterized protein. (163 aa)
GNB3G protein subunit beta 3. (340 aa)
PDE4BPhosphodiesterase. (564 aa)
PRKACBProtein kinase cAMP-activated catalytic subunit beta; Belongs to the protein kinase superfamily. (398 aa)
ENSRROP00000005502Protein kinase domain-containing protein. (325 aa)
GNGT2Guanine nucleotide-binding protein subunit gamma; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction. (101 aa)
DCLK1Doublecortin like kinase 1. (740 aa)
PLCB21-phosphatidylinositol 4,5-bisphosphate phosphodiesterase; The production of the second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3) is mediated by activated phosphatidylinositol-specific phospholipase C enzymes. (1162 aa)
ADCY5Adenylate cyclase 5; Belongs to the adenylyl cyclase class-4/guanylyl cyclase family. (864 aa)
GNG2Guanine nucleotide-binding protein subunit gamma; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction. (110 aa)
CAMK4Calcium/calmodulin dependent protein kinase IV. (274 aa)
ENSRROP00000003001Uncharacterized protein. (93 aa)
ENSRROP00000002323IBB domain-containing protein. (436 aa)
GNGT1Guanine nucleotide-binding protein subunit gamma; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction. (89 aa)
ADCY4Adenylate cyclase type 4; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling. (1077 aa)
ADCY8Adenylate cyclase type 8; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling. (1043 aa)
CAMK2DCalcium/calmodulin dependent protein kinase II delta. (533 aa)
ENSRROP00000045475G protein gamma domain-containing protein. (58 aa)
PPP3CASerine/threonine-protein phosphatase. (417 aa)
POMCProopiomelanocortin. (251 aa)
GNG8Guanine nucleotide-binding protein subunit gamma; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction. (73 aa)
CAMKK2Calcium/calmodulin dependent protein kinase kinase 2. (588 aa)
ITPR1Inositol 1,4,5-trisphosphate receptor type 1. (2714 aa)
PDE1CPhosphodiesterase. (768 aa)
LOC104677425Uncharacterized protein. (157 aa)
PRKCAProtein kinase C; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. PKC subfamily. (672 aa)
GNG12Guanine nucleotide-binding protein subunit gamma; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction. (72 aa)
ADCY3Adenylate cyclase type 3; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling. (1147 aa)
ADCY6Adenylate cyclase 6; Belongs to the adenylyl cyclase class-4/guanylyl cyclase family. (603 aa)
GNB2G protein subunit beta 2. (340 aa)
PDYNProdynorphin. (254 aa)
ENSRROP00000038862Protein kinase domain-containing protein. (265 aa)
GNG11Guanine nucleotide-binding protein subunit gamma; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction. (74 aa)
CAMK2GCalcium/calmodulin dependent protein kinase II gamma. (559 aa)
PRKAR2AProtein kinase cAMP-dependent type II regulatory subunit alpha. (404 aa)
OPRM1Opioid receptor mu 1; Belongs to the G-protein coupled receptor 1 family. (446 aa)
ADCY7Adenylate cyclase type 7; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling. (1095 aa)
PPP2R5DSerine/threonine-protein phosphatase 2A 56 kDa regulatory subunit; The B regulatory subunit might modulate substrate selectivity and catalytic activity, and also might direct the localization of the catalytic enzyme to a particular subcellular compartment. (605 aa)
GNB4G protein subunit beta 4. (340 aa)
PRKAR2BProtein kinase cAMP-dependent type II regulatory subunit beta. (429 aa)
ENSRROP00000035890G protein gamma domain-containing protein. (68 aa)
ITPR3Inositol 1,4,5-trisphosphate receptor type 3. (2703 aa)
GNAQG protein subunit alpha q. (359 aa)
GNG5Guanine nucleotide-binding protein subunit gamma; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction. (68 aa)
PDE1BPhosphodiesterase. (564 aa)
CAMK2BCalcium/calmodulin dependent protein kinase II beta. (653 aa)
NBEA-2Uncharacterized protein. (334 aa)
ENSRROP00000034142annotation not available (59 aa)
THAP7THAP domain containing 7. (309 aa)
GNG4Guanine nucleotide-binding protein subunit gamma; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction. (75 aa)
PPP1CASerine/threonine-protein phosphatase; Belongs to the PPP phosphatase family. (367 aa)
LRBALPS responsive beige-like anchor protein. (2853 aa)
GNB5G protein subunit beta 5. (403 aa)
PPP2R1AProtein phosphatase 2 scaffold subunit Aalpha. (589 aa)
ENSRROP00000029359Uncharacterized protein. (71 aa)
CAMKK1Calcium/calmodulin dependent protein kinase kinase 1. (532 aa)
GNG3Guanine nucleotide-binding protein subunit gamma; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction. (75 aa)
PPP3CCSerine/threonine-protein phosphatase. (520 aa)
GNA14G protein subunit alpha 14. (355 aa)
ADCY9Adenylate cyclase 9; Belongs to the adenylyl cyclase class-4/guanylyl cyclase family. (1353 aa)
PLCB41-phosphatidylinositol 4,5-bisphosphate phosphodiesterase; The production of the second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3) is mediated by activated phosphatidylinositol-specific phospholipase C enzymes. (1225 aa)
AHCYL1Adenosylhomocysteinase like 1; Belongs to the adenosylhomocysteinase family. (530 aa)
PRKAR1AProtein kinase cAMP-dependent type I regulatory subunit alpha. (381 aa)
PPP2CASerine/threonine-protein phosphatase. (309 aa)
MAPK1Mitogen-activated protein kinase. (330 aa)
PDE4CPhosphodiesterase. (676 aa)
GNA15G protein subunit alpha 15. (374 aa)
ITPR2Inositol 1,4,5-trisphosphate receptor type 2. (2700 aa)
Your Current Organism:
Rhinopithecus roxellana
NCBI taxonomy Id: 61622
Other names: Pygathrix roxellana, R. roxellana, golden snub-nosed monkey
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