STRINGSTRING
ELL ELL POLR2H POLR2H CDK7 CDK7 ERCC3 ERCC3 CDK9 CDK9 NELFE NELFE MLLT1 MLLT1 AFF1 AFF1 POLR2C POLR2C NCBP1 NCBP1 POLR2A POLR2A GTF2H3 GTF2H3 IWS1 IWS1 EAF1 EAF1 LOC104657870 LOC104657870 ENSRROP00000007615 ENSRROP00000007615 POLR2B POLR2B LOC104674456 LOC104674456 PAF1 PAF1 POLR2D POLR2D SUPT5H SUPT5H GTF2F1 GTF2F1 POLR2F POLR2F ENSRROP00000004459 ENSRROP00000004459 CDC73 CDC73 TCEA1 TCEA1 ENSRROP00000000351 ENSRROP00000000351 ENSRROP00000045588 ENSRROP00000045588 EAF2 EAF2 CCNK CCNK ENSRROP00000012907 ENSRROP00000012907 ELOC ELOC GTF2F2 GTF2F2 NCBP2 NCBP2 NELFCD NELFCD ENSRROP00000017569 ENSRROP00000017569 ENSRROP00000018014 ENSRROP00000018014 POLR2G POLR2G AFF4 AFF4 CTR9 CTR9 CTDP1 CTDP1 CCNH CCNH SSRP1 SSRP1 SUPT6H SUPT6H POLR2J POLR2J MNAT1 MNAT1 LEO1 LEO1 ENSRROP00000026238 ENSRROP00000026238 ENSRROP00000029240 ENSRROP00000029240 CCNT2 CCNT2 MLLT3 MLLT3 GTF2H5 GTF2H5 GTF2H2 GTF2H2 ELOA ELOA ELOA2 ELOA2 NELFA NELFA ERCC2 ERCC2 SUPT4H1 SUPT4H1 SUPT16H SUPT16H POLR2L POLR2L GTF2H4 GTF2H4 CCNT1 CCNT1 GTF2H1 GTF2H1 NELFB NELFB POLR2K POLR2K POLR2E POLR2E WDR61 WDR61 RTF1 RTF1 ENSRROP00000039400 ENSRROP00000039400 POLR2I POLR2I
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
ELLElongation factor for RNA polymerase II. (621 aa)
POLR2HRNA polymerase II subunit H. (174 aa)
CDK7Cyclin dependent kinase 7; Belongs to the protein kinase superfamily. (346 aa)
ERCC3ERCC excision repair 3, TFIIH core complex helicase subunit. (782 aa)
CDK9Cyclin dependent kinase 9; Belongs to the protein kinase superfamily. (372 aa)
NELFENegative elongation factor complex member E. (390 aa)
MLLT1MLLT1 super elongation complex subunit. (391 aa)
AFF1AF4/FMR2 family member 1. (1221 aa)
POLR2CRNA polymerase II subunit C. (275 aa)
NCBP1Nuclear cap binding protein subunit 1. (790 aa)
POLR2ADNA-directed RNA polymerase subunit; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. (1992 aa)
GTF2H3General transcription factor IIH subunit 3. (308 aa)
IWS1Interacts with SUPT6H, CTD assembly factor 1. (823 aa)
EAF1ELL associated factor 1. (268 aa)
LOC104657870Skp1_POZ domain-containing protein; Belongs to the SKP1 family. (115 aa)
ENSRROP00000007615Uncharacterized protein. (466 aa)
POLR2BDNA-directed RNA polymerase subunit beta; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. (1174 aa)
LOC104674456Ubiquitin-like domain-containing protein. (118 aa)
PAF1PAF1 homolog, Paf1/RNA polymerase II complex component. (557 aa)
POLR2DRNA polymerase II subunit D. (142 aa)
SUPT5HTranscription elongation factor SPT5. (1087 aa)
GTF2F1Transcription initiation factor IIF subunit alpha; TFIIF is a general transcription initiation factor that binds to RNA polymerase II and helps to recruit it to the initiation complex in collaboration with TFIIB. It promotes transcription elongation. Belongs to the TFIIF alpha subunit family. (545 aa)
POLR2FRNA polymerase II subunit F. (150 aa)
ENSRROP00000004459Skp1_POZ domain-containing protein. (93 aa)
CDC73Cell division cycle 73. (531 aa)
TCEA1Transcription elongation factor A1. (301 aa)
ENSRROP00000000351Uncharacterized protein. (67 aa)
ENSRROP00000045588Ubiquitin-like domain-containing protein. (137 aa)
EAF2ELL associated factor 2. (263 aa)
CCNKCyclin K; Belongs to the cyclin family. (493 aa)
ENSRROP00000012907Uncharacterized protein. (116 aa)
ELOCSkp1_POZ domain-containing protein; Belongs to the SKP1 family. (112 aa)
GTF2F2General transcription factor IIF subunit 2; TFIIF is a general transcription initiation factor that binds to RNA polymerase II and helps to recruit it to the initiation complex in collaboration with TFIIB. It promotes transcription elongation. This subunit shows ATP-dependent DNA-helicase activity. (249 aa)
NCBP2Nuclear cap-binding protein subunit 2; Component of the cap-binding complex (CBC), which binds co- transcriptionally to the 5' cap of pre-mRNAs and is involved in various processes such as pre-mRNA splicing, translation regulation, nonsense- mediated mRNA decay, RNA-mediated gene silencing (RNAi) by microRNAs (miRNAs) and mRNA export. The CBC complex is involved in mRNA export from the nucleus, leading to the recruitment of the mRNA export machinery to the 5' end of mRNA and to mRNA export in a 5' to 3' direction through the nuclear pore. The CBC complex is also involved in mediating U [...] (166 aa)
NELFCDNegative elongation factor complex member C/D. (588 aa)
ENSRROP00000017569Transcription initiation factor IIF subunit alpha; TFIIF is a general transcription initiation factor that binds to RNA polymerase II and helps to recruit it to the initiation complex in collaboration with TFIIB. It promotes transcription elongation. Belongs to the TFIIF alpha subunit family. (442 aa)
ENSRROP00000018014Protein kinase domain-containing protein. (315 aa)
POLR2GRNA polymerase II subunit G. (255 aa)
AFF4AF4/FMR2 family member 4. (1163 aa)
CTR9CTR9 homolog, Paf1/RNA polymerase II complex component. (1173 aa)
CTDP1CTD phosphatase subunit 1. (947 aa)
CCNHCyclin H; Belongs to the cyclin family. (325 aa)
SSRP1FACT complex subunit SSRP1; Component of the FACT complex, a general chromatin factor that acts to reorganize nucleosomes. The FACT complex is involved in multiple processes that require DNA as a template such as mRNA elongation, DNA replication and DNA repair. During transcription elongation the FACT complex acts as a histone chaperone that both destabilizes and restores nucleosomal structure. It facilitates the passage of RNA polymerase II and transcription by promoting the dissociation of one histone H2A-H2B dimer from the nucleosome, then subsequently promotes the reestablishment o [...] (709 aa)
SUPT6HTranscription elongation factor spt6; Transcription elongation factor that enhances transcription elongation by RNA polymerase II (RNAPII). Belongs to the SPT6 family. (1726 aa)
POLR2JRNA_pol_L_2 domain-containing protein. (158 aa)
MNAT1CDK-activating kinase assembly factor MAT1; Stabilizes the cyclin H-CDK7 complex to form a functional CDK-activating kinase (CAK) enzymatic complex. (309 aa)
LEO1LEO1 homolog, Paf1/RNA polymerase II complex component. (666 aa)
ENSRROP00000026238Uncharacterized protein. (71 aa)
ENSRROP00000029240Nuclear cap-binding protein subunit 2; Component of the cap-binding complex (CBC), which binds co- transcriptionally to the 5' cap of pre-mRNAs and is involved in various processes such as pre-mRNA splicing, translation regulation, nonsense- mediated mRNA decay, RNA-mediated gene silencing (RNAi) by microRNAs (miRNAs) and mRNA export. The CBC complex is involved in mRNA export from the nucleus, leading to the recruitment of the mRNA export machinery to the 5' end of mRNA and to mRNA export in a 5' to 3' direction through the nuclear pore. The CBC complex is also involved in mediating U [...] (103 aa)
CCNT2Cyclin T2; Belongs to the cyclin family. (730 aa)
MLLT3MLLT3 super elongation complex subunit. (554 aa)
GTF2H5General transcription factor IIH subunit 5. (71 aa)
GTF2H2General transcription factor IIH subunit. (395 aa)
ELOAElongin A. (839 aa)
ELOA2TFIIS N-terminal domain-containing protein. (550 aa)
NELFANegative elongation factor complex member A. (539 aa)
ERCC2ERCC excision repair 2, TFIIH core complex helicase subunit. (760 aa)
SUPT4H1Transcription elongation factor SPT4; Component of the DRB sensitivity-inducing factor complex (DSIF complex), which regulates transcription elongation by RNA polymerase II; Belongs to the SPT4 family. (117 aa)
SUPT16HSPT16 homolog, facilitates chromatin remodeling subunit. (1047 aa)
POLR2LRNA polymerase II subunit L. (67 aa)
GTF2H4General transcription factor IIH subunit 4; Component of the general transcription and DNA repair factor IIH (TFIIH) core complex which is involved in general and transcription-coupled nucleotide excision repair (NER) of damaged DNA. Belongs to the TFB2 family. (462 aa)
CCNT1Cyclin T1; Belongs to the cyclin family. (728 aa)
GTF2H1General transcription factor IIH subunit 1. (557 aa)
NELFBNegative elongation factor complex member B. (629 aa)
POLR2KRNA polymerase II subunit K. (58 aa)
POLR2ERNA polymerase II subunit E. (210 aa)
WDR61WD repeat domain 61. (305 aa)
RTF1RTF1 homolog, Paf1/RNA polymerase II complex component. (710 aa)
ENSRROP00000039400Uncharacterized protein; Belongs to the SKP1 family. (100 aa)
POLR2IDNA-directed RNA polymerase subunit; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. Belongs to the archaeal rpoM/eukaryotic RPA12/RPB9/RPC11 RNA polymerase family. (125 aa)
Your Current Organism:
Rhinopithecus roxellana
NCBI taxonomy Id: 61622
Other names: Pygathrix roxellana, R. roxellana, golden snub-nosed monkey
Server load: low (32%) [HD]