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| | ACLY | ATP-citrate synthase; Catalyzes the cleavage of citrate into oxaloacetate and acetyl-CoA, the latter serving as common substrate for de novo cholesterol and fatty acid synthesis; In the N-terminal section; belongs to the succinate/malate CoA ligase beta subunit family. (1148 aa) |
| | ADCY8 | Adenylate cyclase type 8; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling. (1043 aa) |
| | ADCY4 | Adenylate cyclase type 4; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling. (1077 aa) |
| | KCNS3 | Potassium voltage-gated channel modifier subfamily S member 3; Belongs to the potassium channel family. (491 aa) |
| | GNGT1 | Guanine nucleotide-binding protein subunit gamma; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction. (89 aa) |
| | ACSL3 | Acyl-CoA synthetase long chain family member 3. (720 aa) |
| | TKTL2 | Transketolase like 2. (722 aa) |
| | STXBP1 | Syntaxin binding protein 1; Belongs to the STXBP/unc-18/SEC1 family. (603 aa) |
| | GNG2 | Guanine nucleotide-binding protein subunit gamma; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction. (110 aa) |
| | ADCY5 | Adenylate cyclase 5; Belongs to the adenylyl cyclase class-4/guanylyl cyclase family. (864 aa) |
| | PLCB2 | 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase; The production of the second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3) is mediated by activated phosphatidylinositol-specific phospholipase C enzymes. (1162 aa) |
| | PRKAB2 | Protein kinase AMP-activated non-catalytic subunit beta 2. (272 aa) |
| | ADIPOR2 | Adiponectin receptor 2. (386 aa) |
| | AKAP5 | A-kinase anchoring protein 5. (427 aa) |
| | FFAR1 | Free fatty acid receptor 1. (300 aa) |
| | GNGT2 | Guanine nucleotide-binding protein subunit gamma; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction. (101 aa) |
| | PRKACB | Protein kinase cAMP-activated catalytic subunit beta; Belongs to the protein kinase superfamily. (398 aa) |
| | STK11 | Serine/threonine kinase 11; Belongs to the protein kinase superfamily. (433 aa) |
| | RAPGEF4 | Rap guanine nucleotide exchange factor 4. (1011 aa) |
| | CD36 | CD36 molecule; Belongs to the CD36 family. (472 aa) |
| | GNB3 | G protein subunit beta 3. (340 aa) |
| | ENSRROP00000006154 | Uncharacterized protein. (163 aa) |
| | KCNJ11 | Potassium voltage-gated channel subfamily J member 11. (390 aa) |
| | ENSRROP00000007762 | Guanine nucleotide-binding protein subunit gamma; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction. (69 aa) |
| | STX1A | Syntaxin 1A; Belongs to the syntaxin family. (289 aa) |
| | KCNC2 | Potassium voltage-gated channel subfamily C member 2; Belongs to the potassium channel family. (638 aa) |
| | GNG7 | Guanine nucleotide-binding protein subunit gamma; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction. (68 aa) |
| | KCNB1 | Potassium voltage-gated channel subfamily B member 1; Belongs to the potassium channel family. (858 aa) |
| | ADCY1 | Adenylate cyclase type 1; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling. (1075 aa) |
| | GNAI2 | G protein subunit alpha i2. (355 aa) |
| | PRKAG2 | Protein kinase AMP-activated non-catalytic subunit gamma 2. (568 aa) |
| | GNG13 | G protein subunit gamma 13. (67 aa) |
| | PRKACA | Protein kinase cAMP-activated catalytic subunit alpha; Belongs to the protein kinase superfamily. (351 aa) |
| | VAMP2 | V-SNARE coiled-coil homology domain-containing protein. (193 aa) |
| | ADCY2 | Adenylate cyclase type 2; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling. (1052 aa) |
| | CACNA1E | Voltage-dependent R-type calcium channel subunit alpha; Voltage-sensitive calcium channels (VSCC) mediate the entry of calcium ions into excitable cells and are also involved in a variety of calcium-dependent processes, including muscle contraction, hormone or neurotransmitter release, gene expression, cell motility, cell division and cell death. The isoform alpha-1E gives rise to R-type calcium currents. (2313 aa) |
| | RAPGEFL1 | Rap guanine nucleotide exchange factor like 1. (669 aa) |
| | CACNA2D2 | Calcium voltage-gated channel auxiliary subunit alpha2delta 2. (1124 aa) |
| | ENSRROP00000013107 | Uncharacterized protein. (128 aa) |
| | ADIPOQ | Adiponectin, C1Q and collagen domain containing. (244 aa) |
| | CACNB2 | Calcium voltage-gated channel auxiliary subunit beta 2. (660 aa) |
| | RAPGEF3 | Rap guanine nucleotide exchange factor 3. (923 aa) |
| | PPP2CB | Serine/threonine-protein phosphatase. (312 aa) |
| | CNBD2 | Cyclic nucleotide binding domain containing 2. (581 aa) |
| | GNB1 | G protein subunit beta 1. (340 aa) |
| | GNA11 | G protein subunit alpha 11. (359 aa) |
| | ADIPOR1 | Adiponectin receptor 1. (375 aa) |
| | AGPAT1 | 1-acyl-sn-glycerol-3-phosphate acyltransferase; Belongs to the 1-acyl-sn-glycerol-3-phosphate acyltransferase family. (283 aa) |
| | PRKAR1B | Protein kinase cAMP-dependent type I regulatory subunit beta. (381 aa) |
| | PPP2R1B | Protein phosphatase 2 scaffold subunit Abeta. (667 aa) |
| | ENSRROP00000019238 | Voltage-dependent L-type calcium channel subunit alpha; Voltage-sensitive calcium channels (VSCC) mediate the entry of calcium ions into excitable cells and are also involved in a variety of calcium-dependent processes, including muscle contraction, hormone or neurotransmitter release, gene expression, cell motility, cell division and cell death; Belongs to the calcium channel alpha-1 subunit (TC 1.A.1.11) family. (785 aa) |
| | ACACA | Acetyl-CoA carboxylase alpha. (2383 aa) |
| | PLCB3 | 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase; The production of the second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3) is mediated by activated phosphatidylinositol-specific phospholipase C enzymes. (1234 aa) |
| | MLX | MAX dimerization protein MLX. (298 aa) |
| | THAP6 | THAP domain containing 6. (222 aa) |
| | MARCKS | Myristoylated alanine rich protein kinase C substrate. (285 aa) |
| | ENSRROP00000022234 | Guanine nucleotide-binding protein subunit gamma; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction. (59 aa) |
| | PLCB1 | 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase; The production of the second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3) is mediated by activated phosphatidylinositol-specific phospholipase C enzymes. (1114 aa) |
| | GNG8 | Guanine nucleotide-binding protein subunit gamma; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction. (73 aa) |
| | KCNG2 | Potassium voltage-gated channel modifier subfamily G member 2; Belongs to the potassium channel family. (378 aa) |
| | ITPR2 | Inositol 1,4,5-trisphosphate receptor type 2. (2700 aa) |
| | CACNA1D | Voltage-dependent L-type calcium channel subunit alpha; Voltage-sensitive calcium channels (VSCC) mediate the entry of calcium ions into excitable cells and are also involved in a variety of calcium-dependent processes, including muscle contraction, hormone or neurotransmitter release, gene expression, cell motility, cell division and cell death; Belongs to the calcium channel alpha-1 subunit (TC 1.A.1.11) family. (2181 aa) |
| | GNA15 | G protein subunit alpha 15. (374 aa) |
| | PPP2CA | Serine/threonine-protein phosphatase. (309 aa) |
| | IQGAP1 | IQ motif containing GTPase activating protein 1. (1696 aa) |
| | GLP1R | Glucagon like peptide 1 receptor; Belongs to the G-protein coupled receptor 2 family. (463 aa) |
| | ACSL4 | Acyl-CoA synthetase long chain family member 4. (711 aa) |
| | PRKAR1A | Protein kinase cAMP-dependent type I regulatory subunit alpha. (381 aa) |
| | AHCYL1 | Adenosylhomocysteinase like 1; Belongs to the adenosylhomocysteinase family. (530 aa) |
| | SLC2A2 | Solute carrier family 2 member 2; Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family. (524 aa) |
| | ADCY9 | Adenylate cyclase 9; Belongs to the adenylyl cyclase class-4/guanylyl cyclase family. (1353 aa) |
| | GNA14 | G protein subunit alpha 14. (355 aa) |
| | FAP | Fibroblast activation protein alpha; Belongs to the peptidase S9B family. (760 aa) |
| | GNG3 | Guanine nucleotide-binding protein subunit gamma; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction. (75 aa) |
| | PKLR | Pyruvate kinase; Belongs to the pyruvate kinase family. (574 aa) |
| | SLC2A1 | Solute carrier family 2 member 1; Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family. (506 aa) |
| | CACNA1A | Voltage-dependent P/Q-type calcium channel subunit alpha; Voltage-sensitive calcium channels (VSCC) mediate the entry of calcium ions into excitable cells and are also involved in a variety of calcium-dependent processes, including muscle contraction, hormone or neurotransmitter release, gene expression, cell motility, cell division and cell death. The isoform alpha-1A gives rise to P and/or Q- type calcium currents. (2426 aa) |
| | RAPGEF5 | Rap guanine nucleotide exchange factor 5. (730 aa) |
| | PFKFB1 | 6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 1. (366 aa) |
| | SYT5 | Synaptotagmin 5. (386 aa) |
| | CACNA1C | Ca_chan_IQ domain-containing protein. (829 aa) |
| | CACNA2D1 | Calcium voltage-gated channel auxiliary subunit alpha2delta 1. (1103 aa) |
| | TKT | Transketolase. (631 aa) |
| | ABCC8 | ATP binding cassette subfamily C member 8. (1585 aa) |
| | PPP2R1A | Protein phosphatase 2 scaffold subunit Aalpha. (589 aa) |
| | GNB5 | G protein subunit beta 5. (403 aa) |
| | GNG4 | Guanine nucleotide-binding protein subunit gamma; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction. (75 aa) |
| | THAP7 | THAP domain containing 7. (309 aa) |
| | TKTL1 | Transketolase like 1. (540 aa) |
| | PRKAA2 | Non-specific serine/threonine protein kinase. (560 aa) |
| | ACACB | Acetyl-CoA carboxylase beta. (2442 aa) |
| | GCG | Glucagon. (180 aa) |
| | ENSRROP00000034142 | annotation not available (59 aa) |
| | MLXIP | MLX interacting protein. (919 aa) |
| | ENSRROP00000045475 | G protein gamma domain-containing protein. (58 aa) |
| | INS | Insulin; Insulin decreases blood glucose concentration. It increases cell permeability to monosaccharides, amino acids and fatty acids. It accelerates glycolysis, the pentose phosphate cycle, and glycogen synthesis in liver. (110 aa) |
| | CACNA1F | Voltage-dependent L-type calcium channel subunit alpha; Voltage-sensitive calcium channels (VSCC) mediate the entry of calcium ions into excitable cells and are also involved in a variety of calcium-dependent processes, including muscle contraction, hormone or neurotransmitter release, gene expression, cell motility, cell division and cell death; Belongs to the calcium channel alpha-1 subunit (TC 1.A.1.11) family. (1971 aa) |
| | GCGR | Glucagon receptor; Belongs to the G-protein coupled receptor 2 family. (484 aa) |
| | CACNB3 | Calcium voltage-gated channel auxiliary subunit beta 3. (485 aa) |
| | GNG5 | Guanine nucleotide-binding protein subunit gamma; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction. (68 aa) |
| | GNAQ | G protein subunit alpha q. (359 aa) |
| | ITPR3 | Inositol 1,4,5-trisphosphate receptor type 3. (2703 aa) |
| | ENSRROP00000035890 | G protein gamma domain-containing protein. (68 aa) |
| | PRKAR2B | Protein kinase cAMP-dependent type II regulatory subunit beta. (429 aa) |
| | GNB4 | G protein subunit beta 4. (340 aa) |
| | TALDO1 | Transaldolase; Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway. (337 aa) |
| | PPP2R5D | Serine/threonine-protein phosphatase 2A 56 kDa regulatory subunit; The B regulatory subunit might modulate substrate selectivity and catalytic activity, and also might direct the localization of the catalytic enzyme to a particular subcellular compartment. (605 aa) |
| | ADCY7 | Adenylate cyclase type 7; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling. (1095 aa) |
| | SNAP25 | Synaptosomal-associated protein; Belongs to the SNAP-25 family. (206 aa) |
| | PRKAR2A | Protein kinase cAMP-dependent type II regulatory subunit alpha. (404 aa) |
| | GNG11 | Guanine nucleotide-binding protein subunit gamma; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction. (74 aa) |
| | GNAS | GNAS complex locus. (1041 aa) |
| | MLXIPL | MLX interacting protein like. (793 aa) |
| | RAP1A | RAP1A, member of RAS oncogene family. (184 aa) |
| | FASN | Fatty acid synthase. (2504 aa) |
| | GNB2 | G protein subunit beta 2. (340 aa) |
| | ADCY6 | Adenylate cyclase 6; Belongs to the adenylyl cyclase class-4/guanylyl cyclase family. (603 aa) |
| | ADCY3 | Adenylate cyclase type 3; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling. (1147 aa) |
| | GNG12 | Guanine nucleotide-binding protein subunit gamma; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction. (72 aa) |
| | PRKCA | Protein kinase C; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. PKC subfamily. (672 aa) |
| | ITPR1 | Inositol 1,4,5-trisphosphate receptor type 1. (2714 aa) |
