45 items (Rhinopithecus roxellana) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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query proteins and first shell of interactors

white nodes:
second shell of interactors

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proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

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experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	SPNS1	Sphingolipid transporter 1 (putative). (528 aa)
	SYK	Tyrosine-protein kinase. (635 aa)
	SIGLEC14	Sialic acid binding Ig like lectin 14. (396 aa)
	BTK	Tyrosine-protein kinase. (690 aa)
	PIK3R2	Uncharacterized protein. (647 aa)
	PIK3R1	Phosphoinositide-3-kinase regulatory subunit 1. (724 aa)
	CD300E	CD300e molecule. (205 aa)
	HLA-E	Major histocompatibility complex, class I, E; Belongs to the MHC class I family. (364 aa)
	FYN	Tyrosine-protein kinase. (537 aa)
	NRAS	NRAS proto-oncogene, GTPase. (189 aa)
	LOC104676775	Ig-like domain-containing protein; Belongs to the MHC class I family. (391 aa)
	TREM2	Triggering receptor expressed on myeloid cells 2. (230 aa)
	SHC1	SHC adaptor protein 1. (574 aa)
	ENSRROP00000015460	Ig-like domain-containing protein; Belongs to the MHC class I family. (391 aa)
	ENSRROP00000015288	DH domain-containing protein. (263 aa)
	KLRD1	Killer cell lectin like receptor D1. (179 aa)
	VAV2	Vav guanine nucleotide exchange factor 2. (810 aa)
	SOS1	SOS Ras/Rac guanine nucleotide exchange factor 1. (1333 aa)
	LCK	Tyrosine-protein kinase. (561 aa)
	TYROBP	TYRO protein tyrosine kinase binding protein. (123 aa)
	CSDE1	Cold shock domain containing E1. (844 aa)
	PIK3CA	Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit. (1068 aa)
	B2M	Beta-2-microglobulin; Component of the class I major histocompatibility complex (MHC). Involved in the presentation of peptide antigens to the immune system. (119 aa)
	SIGLEC15	Sialic acid binding Ig like lectin 15. (329 aa)
	ENSRROP00000009442	Uncharacterized protein. (179 aa)
	CD300LB	CD300 molecule like family member b. (209 aa)
	NCR2	Natural cytotoxicity triggering receptor 2. (278 aa)
	LAT	Linker for activation of T cells. (270 aa)
	GRAP2	GRB2 related adaptor protein 2. (330 aa)
	PIK3CB	Phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit beta; Belongs to the PI3/PI4-kinase family. (1073 aa)
	PLCG2	1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma; Mediates the production of the second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3). Plays an important role in the regulation of intracellular signaling cascades. (1265 aa)
	LOC104668622	C-type lectin domain-containing protein. (236 aa)
	PLCG1	1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma; Mediates the production of the second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3). Plays an important role in the regulation of intracellular signaling cascades. (1303 aa)
	LCP2	Lymphocyte cytosolic protein 2. (533 aa)
	ERAS	ES cell expressed Ras. (233 aa)
	CLEC5A	C-type lectin domain containing 5A. (188 aa)
	SPNS3	Sphingolipid transporter 3 (putative). (512 aa)
	KRAS	KRAS proto-oncogene, GTPase. (189 aa)
	GRB2	Growth factor receptor bound protein 2. (217 aa)
	HRAS	HRas proto-oncogene, GTPase. (189 aa)
	VAV3	Uncharacterized protein. (287 aa)
	KLRK1	Killer cell lectin like receptor K1. (216 aa)
	KLRC1	Killer cell lectin like receptor C1. (233 aa)
	TREM1	Triggering receptor expressed on myeloid cells 1. (248 aa)
	SIRPB1	Uncharacterized protein. (397 aa)

Your Current Organism:

Rhinopithecus roxellana

NCBI taxonomy Id: 61622
Other names: Pygathrix roxellana, R. roxellana, golden snub-nosed monkey

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
B2M	ENSRROP00000015460	ENSRROP00000010970	ENSRROP00000015460	Beta-2-microglobulin; Component of the class I major histocompatibility complex (MHC). Involved in the presentation of peptide antigens to the immune system.	Ig-like domain-containing protein; Belongs to the MHC class I family.	0.942
B2M	HLA-E	ENSRROP00000010970	ENSRROP00000039422	Beta-2-microglobulin; Component of the class I major histocompatibility complex (MHC). Involved in the presentation of peptide antigens to the immune system.	Major histocompatibility complex, class I, E; Belongs to the MHC class I family.	0.987
B2M	KLRC1	ENSRROP00000010970	ENSRROP00000037187	Beta-2-microglobulin; Component of the class I major histocompatibility complex (MHC). Involved in the presentation of peptide antigens to the immune system.	Killer cell lectin like receptor C1.	0.488
B2M	KLRD1	ENSRROP00000010970	ENSRROP00000015248	Beta-2-microglobulin; Component of the class I major histocompatibility complex (MHC). Involved in the presentation of peptide antigens to the immune system.	Killer cell lectin like receptor D1.	0.683
B2M	LOC104668622	ENSRROP00000010970	ENSRROP00000023979	Beta-2-microglobulin; Component of the class I major histocompatibility complex (MHC). Involved in the presentation of peptide antigens to the immune system.	C-type lectin domain-containing protein.	0.412
B2M	LOC104676775	ENSRROP00000010970	ENSRROP00000016350	Beta-2-microglobulin; Component of the class I major histocompatibility complex (MHC). Involved in the presentation of peptide antigens to the immune system.	Ig-like domain-containing protein; Belongs to the MHC class I family.	0.987
B2M	TYROBP	ENSRROP00000010970	ENSRROP00000012374	Beta-2-microglobulin; Component of the class I major histocompatibility complex (MHC). Involved in the presentation of peptide antigens to the immune system.	TYRO protein tyrosine kinase binding protein.	0.414
BTK	ENSRROP00000015288	ENSRROP00000019847	ENSRROP00000015288	Tyrosine-protein kinase.	DH domain-containing protein.	0.542
BTK	FYN	ENSRROP00000019847	ENSRROP00000018822	Tyrosine-protein kinase.	Tyrosine-protein kinase.	0.519
BTK	GRAP2	ENSRROP00000019847	ENSRROP00000042423	Tyrosine-protein kinase.	GRB2 related adaptor protein 2.	0.740
BTK	GRB2	ENSRROP00000019847	ENSRROP00000034137	Tyrosine-protein kinase.	Growth factor receptor bound protein 2.	0.828
BTK	LAT	ENSRROP00000019847	ENSRROP00000008043	Tyrosine-protein kinase.	Linker for activation of T cells.	0.505
BTK	LCK	ENSRROP00000019847	ENSRROP00000013457	Tyrosine-protein kinase.	Tyrosine-protein kinase.	0.456
BTK	LCP2	ENSRROP00000019847	ENSRROP00000026588	Tyrosine-protein kinase.	Lymphocyte cytosolic protein 2.	0.988
BTK	PIK3CA	ENSRROP00000019847	ENSRROP00000011898	Tyrosine-protein kinase.	Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit.	0.944
BTK	PIK3CB	ENSRROP00000019847	ENSRROP00000043600	Tyrosine-protein kinase.	Phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit beta; Belongs to the PI3/PI4-kinase family.	0.942
BTK	PIK3R1	ENSRROP00000019847	ENSRROP00000021473	Tyrosine-protein kinase.	Phosphoinositide-3-kinase regulatory subunit 1.	0.943
BTK	PLCG1	ENSRROP00000019847	ENSRROP00000024889	Tyrosine-protein kinase.	1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma; Mediates the production of the second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3). Plays an important role in the regulation of intracellular signaling cascades.	0.961
BTK	PLCG2	ENSRROP00000019847	ENSRROP00000044220	Tyrosine-protein kinase.	1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma; Mediates the production of the second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3). Plays an important role in the regulation of intracellular signaling cascades.	0.987
BTK	SHC1	ENSRROP00000019847	ENSRROP00000015849	Tyrosine-protein kinase.	SHC adaptor protein 1.	0.485