STRINGSTRING
XPO1 XPO1 CBL CBL PPP1CA PPP1CA TGFB2 TGFB2 ENSRROP00000035203 ENSRROP00000035203 ENSRROP00000036234 ENSRROP00000036234 LTBP1 LTBP1 LDLRAD4 LDLRAD4 ENSRROP00000037750 ENSRROP00000037750 TGFB1 TGFB1 LTBP3 LTBP3 SMAD7 SMAD7 PPP1CC PPP1CC ITGA8 ITGA8 ITGB6 ITGB6 SMAD4 SMAD4 ITGB1 ITGB1 BAMBI BAMBI NEDD4L NEDD4L LOC104659307 LOC104659307 LOC104657153 LOC104657153 ENSRROP00000003296 ENSRROP00000003296 TGFBR2 TGFBR2 ENSRROP00000003686 ENSRROP00000003686 UBA52 UBA52 SMURF1 SMURF1 UBC UBC PMEPA1 PMEPA1 STRAP STRAP ENSRROP00000015444 ENSRROP00000015444 LTBP4 LTBP4 SMAD3 SMAD3 ENSRROP00000005750 ENSRROP00000005750 ENSRROP00000005625 ENSRROP00000005625 MTMR4 MTMR4 UBE2M UBE2M SMURF2 SMURF2 ITGB8 ITGB8 FKBP1A FKBP1A LOC104657230 LOC104657230 TGFB3 TGFB3 ITGAV ITGAV LOC104659073 LOC104659073 ITGB5 ITGB5 ENSRROP00000021770 ENSRROP00000021770 ZFYVE9 ZFYVE9 PCSK4 PCSK4 ITGB3 ITGB3 SMAD2 SMAD2 NEDD8 NEDD8 TGFBR1 TGFBR1 LTBP2 LTBP2 FURIN FURIN ENSRROP00000026126 ENSRROP00000026126 ENSRROP00000027060 ENSRROP00000027060 PPP1CB PPP1CB USP15 USP15 RPS27A RPS27A FBN1 FBN1 STUB1 STUB1
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
XPO1Exportin 1. (1071 aa)
CBLCbl proto-oncogene. (906 aa)
PPP1CASerine/threonine-protein phosphatase; Belongs to the PPP phosphatase family. (367 aa)
TGFB2Transforming growth factor beta; Belongs to the TGF-beta family. (442 aa)
ENSRROP00000035203Ubiquitin-like domain-containing protein. (141 aa)
ENSRROP00000036234Peptidylprolyl isomerase. (117 aa)
LTBP1Latent transforming growth factor beta binding protein 1. (1691 aa)
LDLRAD4Low density lipoprotein receptor class A domain containing 4. (306 aa)
ENSRROP00000037750Ubiquitin-like domain-containing protein. (121 aa)
TGFB1Transforming growth factor beta; Belongs to the TGF-beta family. (391 aa)
LTBP3Latent transforming growth factor beta binding protein 3. (1069 aa)
SMAD7MH2 domain-containing protein. (211 aa)
PPP1CCSerine/threonine-protein phosphatase; Belongs to the PPP phosphatase family. (337 aa)
ITGA8Integrin subunit alpha 8; Belongs to the integrin alpha chain family. (1063 aa)
ITGB6Integrin beta; Belongs to the integrin beta chain family. (788 aa)
SMAD4Mothers against decapentaplegic homolog. (552 aa)
ITGB1Integrin beta; Belongs to the integrin beta chain family. (801 aa)
BAMBIBMP and activin membrane-bound inhibitor homolog; Negatively regulates TGF-beta signaling. Belongs to the BAMBI family. (260 aa)
NEDD4LNEDD4 like E3 ubiquitin protein ligase. (1255 aa)
LOC104659307TB domain-containing protein. (166 aa)
LOC104657153Ubiquitin-like domain-containing protein. (128 aa)
ENSRROP00000003296Ubiquitin-like domain-containing protein. (96 aa)
TGFBR2TGF-beta receptor type-2; Transmembrane serine/threonine kinase forming with the TGF- beta type I serine/threonine kinase receptor, TGFBR1, the non- promiscuous receptor for the TGF-beta cytokines TGFB1, TGFB2 and TGFB3. Transduces the TGFB1, TGFB2 and TGFB3 signal from the cell surface to the cytoplasm and is thus regulating a plethora of physiological and pathological processes including cell cycle arrest in epithelial and hematopoietic cells, control of mesenchymal cell proliferation and differentiation, wound healing, extracellular matrix production, immunosuppression and carcinoge [...] (592 aa)
ENSRROP00000003686Ubiquitin-like domain-containing protein. (81 aa)
UBA52Ubiquitin A-52 residue ribosomal protein fusion product 1. (232 aa)
SMURF1E3 ubiquitin-protein ligase. (764 aa)
UBCUncharacterized protein. (351 aa)
PMEPA1Prostate transmembrane protein, androgen induced 1. (257 aa)
STRAPSerine/threonine kinase receptor associated protein. (363 aa)
ENSRROP00000015444Peptidylprolyl isomerase. (107 aa)
LTBP4Latent transforming growth factor beta binding protein 4. (1583 aa)
SMAD3Mothers against decapentaplegic homolog. (480 aa)
ENSRROP00000005750Ubiquitin-like domain-containing protein. (77 aa)
ENSRROP00000005625Ubiquitin-like domain-containing protein. (84 aa)
MTMR4Myotubularin related protein 4. (1195 aa)
UBE2MUbiquitin conjugating enzyme E2 M; Belongs to the ubiquitin-conjugating enzyme family. (183 aa)
SMURF2E3 ubiquitin-protein ligase. (741 aa)
ITGB8Integrin beta; Belongs to the integrin beta chain family. (769 aa)
FKBP1APeptidylprolyl isomerase. (127 aa)
LOC104657230Ubiquitin-like domain-containing protein. (156 aa)
TGFB3Transforming growth factor beta; Belongs to the TGF-beta family. (412 aa)
ITGAVIntegrin subunit alpha V; Belongs to the integrin alpha chain family. (1048 aa)
LOC104659073Ubiquitin-like domain-containing protein. (76 aa)
ITGB5Integrin beta; Belongs to the integrin beta chain family. (799 aa)
ENSRROP00000021770Ubiquitin-like domain-containing protein. (166 aa)
ZFYVE9Zinc finger FYVE domain-containing protein. (1425 aa)
PCSK4Proprotein convertase subtilisin/kexin type 4; Belongs to the peptidase S8 family. (754 aa)
ITGB3Integrin beta; Belongs to the integrin beta chain family. (788 aa)
SMAD2Mothers against decapentaplegic homolog. (392 aa)
NEDD8Ubiquitin-like domain-containing protein. (82 aa)
TGFBR1Receptor protein serine/threonine kinase; Belongs to the protein kinase superfamily. (498 aa)
LTBP2Latent transforming growth factor beta binding protein 2. (1821 aa)
FURINFurin, paired basic amino acid cleaving enzyme; Belongs to the peptidase S8 family. (830 aa)
ENSRROP00000026126Ubiquitin-like domain-containing protein. (77 aa)
ENSRROP00000027060Uncharacterized protein. (600 aa)
PPP1CBSerine/threonine-protein phosphatase; Belongs to the PPP phosphatase family. (373 aa)
USP15Ubiquitin carboxyl-terminal hydrolase; Deubiquitinating enzyme that removes conjugated ubiquitin from specific proteins to regulate different cellular processes. Belongs to the peptidase C19 family. (981 aa)
RPS27AUbiquitin-like domain-containing protein. (156 aa)
FBN1Fibrillin 1. (2871 aa)
STUB1STIP1 homology and U-box containing protein 1. (303 aa)
Your Current Organism:
Rhinopithecus roxellana
NCBI taxonomy Id: 61622
Other names: Pygathrix roxellana, R. roxellana, golden snub-nosed monkey
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