STRINGSTRING
NUP188 NUP188 SP4 SP4 RANBP3 RANBP3 NCOA5 NCOA5 PIAS4 PIAS4 MBD1 MBD1 ENSRROP00000016708 ENSRROP00000016708 FOXL2 FOXL2 ING2 ING2 CBX2 CBX2 MAGEB4 MAGEB4 JRK JRK UBA2 UBA2 LOC104668178 LOC104668178 HDAC1 HDAC1 PPARA PPARA SP100 SP100 ENSRROP00000015381 ENSRROP00000015381 NUP98 NUP98 HIC1 HIC1 ENSRROP00000012616 ENSRROP00000012616 INCENP INCENP MITF MITF LOC104653904 LOC104653904 NUP62 NUP62 XRCC4 XRCC4 ZNF618 ZNF618 RAD52 RAD52 ENSRROP00000011286 ENSRROP00000011286 TOP2B TOP2B SP140L SP140L NUP62CL NUP62CL NUP153 NUP153 ENSRROP00000011040 ENSRROP00000011040 NUP42 NUP42 PCNA PCNA CHD3 CHD3 HIPK2 HIPK2 LOC104657669 LOC104657669 SP140 SP140 SAE1 SAE1 HNRNPK HNRNPK LOC104676547 LOC104676547 TDG TDG ENSRROP00000014234 ENSRROP00000014234 TFE3 TFE3 NSMCE1 NSMCE1 TP53BP1 TP53BP1 NUP160 NUP160 IKBKG IKBKG ENSRROP00000005396 ENSRROP00000005396 TRIM7 TRIM7 MEIOB MEIOB RAD21 RAD21 TIGD3 TIGD3 ENSRROP00000006359 ENSRROP00000006359 JRKL JRKL ENSRROP00000006684 ENSRROP00000006684 E4F1 E4F1 RANBP2 RANBP2 NUP35 NUP35 NUP205 NUP205 ENSRROP00000045760 ENSRROP00000045760 RANGAP1 RANGAP1 NR2C1 NR2C1 NR1H3 NR1H3 SP5 SP5 CTBP1 CTBP1 DDX17 DDX17 WRN WRN ENSRROP00000044797 ENSRROP00000044797 ENSRROP00000044793 ENSRROP00000044793 NUP93 NUP93 NPM1 NPM1 LOC104678360 LOC104678360 POM121C POM121C NUP155 NUP155 PPARG PPARG SATB2 SATB2 SIN3A SIN3A ENSRROP00000043193 ENSRROP00000043193 ENSRROP00000043101 ENSRROP00000043101 RAE1 RAE1 NR5A1 NR5A1 RORA RORA ENSRROP00000042387 ENSRROP00000042387 PARK7 PARK7 LOC104664457 LOC104664457 ENSRROP00000041906 ENSRROP00000041906 KCTD2 KCTD2 UBE2I UBE2I RNF168 RNF168 ENSRROP00000041057 ENSRROP00000041057 SCMH1 SCMH1 NUP88 NUP88 TOP1 TOP1 RPA1 RPA1 PCGF2 PCGF2 SCML2 SCML2 PHC2 PHC2 RXRA RXRA FAM111A FAM111A SP110 SP110 NCOR2 NCOR2 PIAS2 PIAS2 ENSRROP00000038566 ENSRROP00000038566 ENSRROP00000038550 ENSRROP00000038550 MRTFA MRTFA LOC104672515 LOC104672515 SHLD1 SHLD1 NUP210 NUP210 ENSRROP00000036868 ENSRROP00000036868 TFEB TFEB SENP1 SENP1 PHC3 PHC3 LOC104661278 LOC104661278 LOC104675025 LOC104675025 NCOA1 NCOA1 RWDD3 RWDD3 LOC104659393 LOC104659393 LOC104669076 LOC104669076 TFAP2C TFAP2C RECQL4 RECQL4 SEC13 SEC13 TRIM28 TRIM28 ENSRROP00000034135 ENSRROP00000034135 CBX5 CBX5 ENSRROP00000033818 ENSRROP00000033818 SATB1 SATB1 NR1H4 NR1H4 BRCA1 BRCA1 NR1H2 NR1H2 NCOA2 NCOA2 ENSRROP00000033278 ENSRROP00000033278 AAAS AAAS NUP107 NUP107 MAGEE1 MAGEE1 AURKA AURKA HMGN5 HMGN5 ENSRROP00000032123 ENSRROP00000032123 AURKB AURKB DNMT1 DNMT1 XPC XPC LOC104658081 LOC104658081 LOC104677352 LOC104677352 PHC1 PHC1 VDR VDR SEH1L SEH1L RANBP3L RANBP3L SMC1A SMC1A NOP58 NOP58 BLM BLM EP300 EP300 SENP5 SENP5 NUP43 NUP43 NSMCE2 NSMCE2 TIGD2 TIGD2 ZBED4 ZBED4 LOC104673770 LOC104673770 TP53 TP53 AURKC AURKC SUZ12 SUZ12 NFKBIA NFKBIA NR5A2 NR5A2 TOP1MT TOP1MT ENSRROP00000026299 ENSRROP00000026299 ENSRROP00000007022 ENSRROP00000007022 NR1I2 NR1I2 ENSRROP00000007233 ENSRROP00000007233 NRIP1 NRIP1 LOC104663449 LOC104663449 SENP2 SENP2 ENSRROP00000007609 ENSRROP00000007609 CBX4 CBX4 SMC5 SMC5 NR3C1 NR3C1 LOC104663422 LOC104663422 RWDD2A RWDD2A THRB THRB ENSRROP00000008956 ENSRROP00000008956 CDCA8 CDCA8 LOC104661434 LOC104661434 RNF2 RNF2 SCML1 SCML1 CETN2 CETN2 PIAS1 PIAS1 PARP1 PARP1 ZNF131 ZNF131 SAFB SAFB CBX8 CBX8 ENSRROP00000026203 ENSRROP00000026203 ENSRROP00000026172 ENSRROP00000026172 LOC104659226 LOC104659226 NUP210L NUP210L AR AR CETN3 CETN3 NFATC2IP NFATC2IP TFAP2B TFAP2B L3MBTL2 L3MBTL2 PIAS3 PIAS3 STAG2 STAG2 HDAC4 HDAC4 LOC104679892 LOC104679892 SP3 SP3 IKBKE IKBKE ENSRROP00000023864 ENSRROP00000023864 CENPB CENPB ENSRROP00000023500 ENSRROP00000023500 TRIM27 TRIM27 TIGD7 TIGD7 LOC104660381 LOC104660381 TOPORS TOPORS ENSRROP00000002380 ENSRROP00000002380 THRA THRA ZBTB38 ZBTB38 PPARGC1A PPARGC1A ENSRROP00000002615 ENSRROP00000002615 RWDD2B RWDD2B ENSRROP00000002977 ENSRROP00000002977 ENSRROP00000003282 ENSRROP00000003282 NUP37 NUP37 LOC104659175 LOC104659175 SMC3 SMC3 PML PML NUP58 NUP58 TPR TPR RELA RELA MTA1 MTA1 LOC104665118 LOC104665118 ENSRROP00000004783 ENSRROP00000004783 TIGD6 TIGD6 TIGD4 TIGD4 FAM111B FAM111B TIGD1 TIGD1 SMC6 SMC6 LOC104655509 LOC104655509 SUMO1 SUMO1 ING1 ING1 NUP50 NUP50 PGR PGR HIC2 HIC2 ENSRROP00000022479 ENSRROP00000022479 NSMCE4A NSMCE4A BMI1 BMI1 POGK POGK NDC1 NDC1 TOP2A TOP2A NUP214 NUP214 DDX5 DDX5 CREBBP CREBBP DNMT3B DNMT3B LOC104666382 LOC104666382 VHL VHL MAGEB6 MAGEB6 CTXN2 CTXN2 SUMO2-2 SUMO2-2 LOC104666383 LOC104666383 ENSRROP00000001218 ENSRROP00000001218 NUP133 NUP133 MAGEE2 MAGEE2 ENSRROP00000001510 ENSRROP00000001510 MAGEF1 MAGEF1 MDC1 MDC1 LOC104663570 LOC104663570 HDAC7 HDAC7 SAFB2 SAFB2 LOC104663484 LOC104663484 ENSRROP00000001958 ENSRROP00000001958 NUP54 NUP54 NR4A2 NR4A2 ENSRROP00000021317 ENSRROP00000021317 UHRF2 UHRF2 NR3C2 NR3C2 STAG1 STAG1 RNF169 RNF169 NFKB2 NFKB2 VTCN1 VTCN1 LOC104653593 LOC104653593 NUP85 NUP85 CFAP53 CFAP53 ZNF350 ZNF350 TFAP2A TFAP2A CASP8AP2 CASP8AP2 ENSRROP00000019405 ENSRROP00000019405 SUMO2 SUMO2 SKOR2 SKOR2 RING1 RING1 ZMIZ1 ZMIZ1 ZMIZ2 ZMIZ2 DNMT3A DNMT3A ENSRROP00000018074 ENSRROP00000018074 RARA RARA HDAC2 HDAC2 DAXX DAXX CENPBD1 CENPBD1 POGZ POGZ
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
NUP188Nucleoporin 188. (1760 aa)
SP4Sp4 transcription factor. (784 aa)
RANBP3RAN binding protein 3. (576 aa)
NCOA5Nuclear receptor coactivator 5. (579 aa)
PIAS4Protein inhibitor of activated STAT 4. (529 aa)
MBD1Methyl-CpG binding domain protein 1. (630 aa)
ENSRROP00000016708WD_REPEATS_REGION domain-containing protein. (376 aa)
FOXL2Forkhead box L2. (374 aa)
ING2Inhibitor of growth protein. (280 aa)
CBX2Chromobox 2. (521 aa)
MAGEB4MAGE family member B4. (268 aa)
JRKJrk helix-turn-helix protein. (556 aa)
UBA2SUMO-activating enzyme subunit 2; The heterodimer acts as an E1 ligase for SUMO1, SUMO2, SUMO3, and probably SUMO4. It mediates ATP-dependent activation of SUMO proteins followed by formation of a thioester bond between a SUMO protein and a conserved active site cysteine residue on UBA2/SAE2. Belongs to the ubiquitin-activating E1 family. (640 aa)
LOC104668178Uncharacterized protein. (392 aa)
HDAC1Histone deacetylase 1; Responsible for the deacetylation of lysine residues on the N-terminal part of the core histones (H2A, H2B, H3 and H4). Histone deacetylation gives a tag for epigenetic repression and plays an important role in transcriptional regulation, cell cycle progression and developmental events. Histone deacetylases act via the formation of large multiprotein complexes. (477 aa)
PPARAPeroxisome proliferator activated receptor alpha. (398 aa)
SP100SP100 nuclear antigen. (797 aa)
ENSRROP00000015381Uncharacterized protein. (406 aa)
NUP98Nucleoporin 98. (1799 aa)
HIC1HIC ZBTB transcriptional repressor 1. (733 aa)
ENSRROP00000012616Uncharacterized protein. (280 aa)
INCENPInner centromere protein. (897 aa)
MITFMelanocyte inducing transcription factor. (526 aa)
LOC104653904Uncharacterized protein. (307 aa)
NUP62Nucleoporin 62. (442 aa)
XRCC4X-ray repair cross complementing 4. (334 aa)
ZNF618Zinc finger protein 618. (954 aa)
RAD52RAD52 homolog, DNA repair protein. (419 aa)
ENSRROP00000011286RRM domain-containing protein. (274 aa)
TOP2BDNA topoisomerase 2; Control of topological states of DNA by transient breakage and subsequent rejoining of DNA strands. Topoisomerase II makes double- strand breaks. (1622 aa)
SP140LSP140 nuclear body protein like. (380 aa)
NUP62CLNucleoporin 62 C-terminal like. (184 aa)
NUP153Nucleoporin 153. (1468 aa)
ENSRROP00000011040Uncharacterized protein. (409 aa)
NUP42Nucleoporin 42. (435 aa)
PCNAProliferating cell nuclear antigen; This protein is an auxiliary protein of DNA polymerase delta and is involved in the control of eukaryotic DNA replication by increasing the polymerase's processibility during elongation of the leading strand; Belongs to the PCNA family. (261 aa)
CHD3Chromodomain helicase DNA binding protein 3. (2014 aa)
HIPK2Homeodomain interacting protein kinase 2. (1197 aa)
LOC104657669RING-type domain-containing protein. (321 aa)
SP140SP140 nuclear body protein. (791 aa)
SAE1SUMO1 activating enzyme subunit 1. (346 aa)
HNRNPKUncharacterized protein. (464 aa)
LOC104676547RRM domain-containing protein. (243 aa)
TDGThymine DNA glycosylase. (410 aa)
ENSRROP00000014234Uncharacterized protein. (63 aa)
TFE3Transcription factor binding to IGHM enhancer 3. (575 aa)
NSMCE1NSE1 homolog, SMC5-SMC6 complex component. (266 aa)
TP53BP1Tumor protein p53 binding protein 1. (1976 aa)
NUP160Nucleoporin 160. (1436 aa)
IKBKGInhibitor of nuclear factor kappa B kinase regulatory subunit gamma. (487 aa)
ENSRROP00000005396annotation not available (103 aa)
TRIM7Tripartite motif containing 7. (511 aa)
MEIOBMeiosis specific with OB-fold. (471 aa)
RAD21RAD21 cohesin complex component. (631 aa)
TIGD3Tigger transposable element derived 3. (471 aa)
ENSRROP00000006359annotation not available (103 aa)
JRKLJRK like. (524 aa)
ENSRROP00000006684annotation not available (103 aa)
E4F1E4F transcription factor 1. (784 aa)
RANBP2RAN binding protein 2. (3191 aa)
NUP35Nucleoporin NUP53; Functions as a component of the nuclear pore complex (NPC). Belongs to the Nup35 family. (326 aa)
NUP205Nucleoporin 205. (2013 aa)
ENSRROP00000045760Uncharacterized protein. (264 aa)
RANGAP1Ran GTPase activating protein 1. (621 aa)
NR2C1Nuclear receptor subfamily 2 group C member 1. (604 aa)
NR1H3Nuclear receptor subfamily 1 group H member 3. (511 aa)
SP5Sp5 transcription factor. (376 aa)
CTBP1C-terminal binding protein 1; Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family. (448 aa)
DDX17DEAD-box helicase 17; Belongs to the DEAD box helicase family. (735 aa)
WRNWRN RecQ like helicase. (1431 aa)
ENSRROP00000044797Ubiquitin-like domain-containing protein. (136 aa)
ENSRROP00000044793BTB domain-containing protein. (145 aa)
NUP93Nuclear pore complex protein Nup93; Plays a role in the nuclear pore complex (NPC) assembly and/or maintenance; Belongs to the nucleoporin interacting component (NIC) family. (880 aa)
NPM1Nucleophosmin 1. (294 aa)
LOC104678360Nuclear receptor domain-containing protein. (231 aa)
POM121CUncharacterized protein. (1107 aa)
NUP155Nucleoporin 155. (1391 aa)
PPARGPeroxisome proliferator-activated receptor gamma; Nuclear receptor that binds peroxisome proliferators such as hypolipidemic drugs and fatty acids. Once activated by a ligand, the nuclear receptor binds to DNA specific PPAR response elements (PPRE) and modulates the transcription of its target genes, such as acyl-CoA oxidase. It therefore controls the peroxisomal beta-oxidation pathway of fatty acids. Key regulator of adipocyte differentiation and glucose homeostasis. ARF6 acts as a key regulator of the tissue-specific adipocyte P2 (aP2) enhancer. Acts as a critical regulator of gut ho [...] (505 aa)
SATB2DNA-binding protein SATB. (733 aa)
SIN3ASIN3 transcription regulator family member A. (1273 aa)
ENSRROP00000043193Protein kinase domain-containing protein. (377 aa)
ENSRROP00000043101Ig-like domain-containing protein. (244 aa)
RAE1Ribonucleic acid export 1. (368 aa)
NR5A1Nuclear receptor subfamily 5 group A member 1. (461 aa)
RORARAR related orphan receptor A. (555 aa)
ENSRROP00000042387BAH domain-containing protein; Belongs to the class I-like SAM-binding methyltransferase superfamily. C5-methyltransferase family. (691 aa)
PARK7Parkinsonism associated deglycase. (189 aa)
LOC104664457Uncharacterized protein. (72 aa)
ENSRROP00000041906YDG domain-containing protein. (711 aa)
KCTD2Potassium channel tetramerization domain containing 2. (263 aa)
UBE2IUbiquitin conjugating enzyme E2 I; Belongs to the ubiquitin-conjugating enzyme family. (231 aa)
RNF168E3 ubiquitin-protein ligase RNF168; E3 ubiquitin-protein ligase required for accumulation of repair proteins to sites of DNA damage. Acts with UBE2N/UBC13 to amplify the RNF8-dependent histone ubiquitination. Recruited to sites of DNA damage at double-strand breaks (DSBs) by binding to ubiquitinated histone H2A and H2AX and amplifies the RNF8-dependent H2A ubiquitination, promoting the formation of 'Lys-63'-linked ubiquitin conjugates. This leads to concentrate ubiquitinated histones H2A and H2AX at DNA lesions to the threshold required for recruitment of TP53BP1 and BRCA1. Also recrui [...] (571 aa)
ENSRROP00000041057Small ubiquitin-related modifier. (122 aa)
SCMH1Scm polycomb group protein homolog 1. (660 aa)
NUP88Nucleoporin 88. (741 aa)
TOP1DNA topoisomerase I; Releases the supercoiling and torsional tension of DNA introduced during the DNA replication and transcription by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at the specific target site 5'-[CT]CCTTp site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(3'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 5'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand thus r [...] (767 aa)
RPA1Replication protein A subunit; As part of the heterotrimeric replication protein A complex (RPA/RP-A), binds and stabilizes single-stranded DNA intermediates, that form during DNA replication or upon DNA stress. It prevents their reannealing and in parallel, recruits and activates different proteins and complexes involved in DNA metabolism. Thereby, it plays an essential role both in DNA replication and the cellular response to DNA damage. (580 aa)
PCGF2Polycomb group ring finger 2. (344 aa)
SCML2SAM domain-containing protein. (139 aa)
PHC2Polyhomeotic homolog 2. (859 aa)
RXRARetinoid X receptor alpha. (481 aa)
FAM111AFamily with sequence similarity 111 member A. (611 aa)
SP110SP110 nuclear body protein. (520 aa)
NCOR2Nuclear receptor corepressor 2. (2522 aa)
PIAS2Protein inhibitor of activated STAT 2. (620 aa)
ENSRROP00000038566Rad60-SLD domain-containing protein. (81 aa)
ENSRROP00000038550Protein kinase domain-containing protein; Belongs to the protein kinase superfamily. (326 aa)
MRTFAMyocardin related transcription factor A. (970 aa)
LOC104672515Uncharacterized protein. (360 aa)
SHLD1Shieldin complex subunit 1. (228 aa)
NUP210Nucleoporin 210. (1856 aa)
ENSRROP00000036868Protein kinase domain-containing protein; Belongs to the protein kinase superfamily. (406 aa)
TFEBTranscription factor EB. (490 aa)
SENP1SUMO specific peptidase 1. (645 aa)
PHC3Polyhomeotic homolog 3. (983 aa)
LOC104661278Uncharacterized protein. (307 aa)
LOC104675025Protein kinase domain-containing protein; Belongs to the protein kinase superfamily. (373 aa)
NCOA1Nuclear receptor coactivator. (1441 aa)
RWDD3RWD domain containing 3. (267 aa)
LOC104659393Uncharacterized protein. (107 aa)
LOC104669076Uncharacterized protein. (107 aa)
TFAP2CTranscription factor AP-2 gamma. (450 aa)
RECQL4RecQ like helicase 4. (1150 aa)
SEC13SEC13 homolog, nuclear pore and COPII coat complex component; Belongs to the WD repeat SEC13 family. (331 aa)
TRIM28Tripartite motif containing 28. (806 aa)
ENSRROP00000034135Poly [ADP-ribose] polymerase. (856 aa)
CBX5Uncharacterized protein. (191 aa)
ENSRROP00000033818E3 ubiquitin-protein ligase Mdm2; Belongs to the MDM2/MDM4 family. (446 aa)
SATB1DNA-binding protein SATB. (795 aa)
NR1H4Nuclear receptor subfamily 1 group H member 4. (486 aa)
BRCA1Breast cancer type 1 susceptibility protein homolog; E3 ubiquitin-protein ligase that specifically mediates the formation of 'Lys-6'-linked polyubiquitin chains and plays a central role in DNA repair by facilitating cellular responses to DNA damage. It is unclear whether it also mediates the formation of other types of polyubiquitin chains. The E3 ubiquitin-protein ligase activity is required for its tumor suppressor function. The BRCA1-BARD1 heterodimer coordinates a diverse range of cellular pathways such as DNA damage repair, ubiquitination and transcriptional regulation to maintain [...] (1836 aa)
NR1H2Nuclear receptor subfamily 1 group H member 2. (461 aa)
NCOA2Nuclear receptor coactivator. (1475 aa)
ENSRROP00000033278Uncharacterized protein. (72 aa)
AAASAladin WD repeat nucleoporin. (546 aa)
NUP107Nuclear pore complex protein; Functions as a component of the nuclear pore complex (NPC). (925 aa)
MAGEE1MAGE family member E1. (891 aa)
AURKAProtein kinase domain-containing protein; Belongs to the protein kinase superfamily. (403 aa)
HMGN5High mobility group nucleosome binding domain 5. (287 aa)
ENSRROP00000032123Uncharacterized protein. (305 aa)
AURKBAurora kinase B; Belongs to the protein kinase superfamily. (344 aa)
DNMT1DNA (cytosine-5)-methyltransferase; Belongs to the class I-like SAM-binding methyltransferase superfamily. C5-methyltransferase family. (1665 aa)
XPCXPC complex subunit, DNA damage recognition and repair factor. (939 aa)
LOC104658081RING-type domain-containing protein. (290 aa)
LOC104677352Histone deacetylase 1; Responsible for the deacetylation of lysine residues on the N-terminal part of the core histones (H2A, H2B, H3 and H4). Histone deacetylation gives a tag for epigenetic repression and plays an important role in transcriptional regulation, cell cycle progression and developmental events. Histone deacetylases act via the formation of large multiprotein complexes. (484 aa)
PHC1Polyhomeotic homolog 1. (1005 aa)
VDRVitamin D receptor. (477 aa)
SEH1LSEH1 like nucleoporin; Belongs to the WD repeat SEC13 family. (431 aa)
RANBP3LRAN binding protein 3 like. (490 aa)
SMC1AStructural maintenance of chromosomes protein. (1251 aa)
NOP58NOP58 ribonucleoprotein. (540 aa)
BLMBLM RecQ like helicase. (1416 aa)
EP300E1A binding protein p300. (2413 aa)
SENP5SUMO specific peptidase 5. (755 aa)
NUP43WD_REPEATS_REGION domain-containing protein. (380 aa)
NSMCE2SP-RING-type domain-containing protein. (246 aa)
TIGD2Tigger transposable element derived 2. (525 aa)
ZBED4Zinc finger BED-type containing 4. (1171 aa)
LOC104673770Proliferating cell nuclear antigen; This protein is an auxiliary protein of DNA polymerase delta and is involved in the control of eukaryotic DNA replication by increasing the polymerase's processibility during elongation of the leading strand; Belongs to the PCNA family. (237 aa)
TP53Cellular tumor antigen p53; Acts as a tumor suppressor in many tumor types; induces growth arrest or apoptosis depending on the physiological circumstances and cell type. Involved in cell cycle regulation as a trans-activator that acts to negatively regulate cell division by controlling a set of genes required for this process. One of the activated genes is an inhibitor of cyclin-dependent kinases. Apoptosis induction seems to be mediated either by stimulation of BAX and FAS antigen expression, or by repression of Bcl-2 expression; Belongs to the p53 family. (393 aa)
AURKCAurora kinase C; Belongs to the protein kinase superfamily. (309 aa)
SUZ12SUZ12 polycomb repressive complex 2 subunit. (739 aa)
NFKBIAANK_REP_REGION domain-containing protein. (343 aa)
NR5A2Nuclear receptor subfamily 5 group A member 2. (538 aa)
TOP1MTDNA topoisomerase I; Releases the supercoiling and torsional tension of DNA introduced during the DNA replication and transcription by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at the specific target site 5'-[CT]CCTTp site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(3'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 5'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand thus r [...] (601 aa)
ENSRROP00000026299ThiF domain-containing protein. (309 aa)
ENSRROP00000007022Uncharacterized protein. (110 aa)
NR1I2Nuclear receptor subfamily 1 group I member 2. (473 aa)
ENSRROP00000007233Uncharacterized protein. (329 aa)
NRIP1Nuclear receptor interacting protein 1. (1155 aa)
LOC104663449Histone H4. (103 aa)
SENP2ULP_PROTEASE domain-containing protein. (588 aa)
ENSRROP00000007609DJ-1_PfpI domain-containing protein. (153 aa)
CBX4Chromobox 4. (546 aa)
SMC5SMC_N domain-containing protein. (1102 aa)
NR3C1Nuclear receptor subfamily 3 group C member 1. (778 aa)
LOC104663422Uncharacterized protein. (297 aa)
RWDD2ARWD domain-containing protein. (292 aa)
THRBThyroid hormone receptor beta. (476 aa)
ENSRROP00000008956Uncharacterized protein. (277 aa)
CDCA8Cell division cycle associated 8. (279 aa)
LOC104661434Uncharacterized protein. (271 aa)
RNF2RING-type domain-containing protein. (336 aa)
SCML1Scm polycomb group protein like 1. (328 aa)
CETN2Centrin 2. (172 aa)
PIAS1Protein inhibitor of activated STAT 1. (653 aa)
PARP1Poly [ADP-ribose] polymerase; Poly-ADP-ribosyltransferase that mediates poly-ADP- ribosylation of proteins and plays a key role in DNA repair. (1014 aa)
ZNF131Zinc finger protein 131. (623 aa)
SAFBScaffold attachment factor B. (917 aa)
CBX8Chromobox 8. (387 aa)
ENSRROP00000026203RRM domain-containing protein. (269 aa)
ENSRROP00000026172Uncharacterized protein. (87 aa)
LOC104659226Histone H4. (103 aa)
NUP210LNucleoporin 210 like. (1888 aa)
ARUncharacterized protein. (523 aa)
CETN3Centrin 3. (191 aa)
NFATC2IPNuclear factor of activated T cells 2 interacting protein. (419 aa)
TFAP2BTranscription factor AP-2 beta. (460 aa)
L3MBTL2L3MBTL histone methyl-lysine binding protein 2. (714 aa)
PIAS3Protein inhibitor of activated STAT 3. (634 aa)
STAG2Stromal antigen 2. (1268 aa)
HDAC4Histone deacetylase; Responsible for the deacetylation of lysine residues on the N-terminal part of the core histones (H2A, H2B, H3 and H4). Histone deacetylation gives a tag for epigenetic repression and plays an important role in transcriptional regulation, cell cycle progression and developmental events. (1085 aa)
LOC104679892BRCT domain-containing protein. (96 aa)
SP3Sp3 transcription factor. (735 aa)
IKBKEInhibitor of nuclear factor kappa B kinase subunit epsilon. (716 aa)
ENSRROP00000023864Uncharacterized protein. (115 aa)
CENPBCentromere protein B. (580 aa)
ENSRROP00000023500Nucleoplasmin domain-containing protein. (214 aa)
TRIM27Tripartite motif containing 27. (513 aa)
TIGD7Tigger transposable element derived 7. (549 aa)
LOC104660381Uncharacterized protein. (702 aa)
TOPORSTOP1 binding arginine/serine rich protein. (1047 aa)
ENSRROP00000002380RRM domain-containing protein. (295 aa)
THRAThyroid hormone receptor alpha. (590 aa)
ZBTB38Zinc finger and BTB domain containing 38. (1195 aa)
PPARGC1APPARG coactivator 1 alpha. (798 aa)
ENSRROP00000002615annotation not available (103 aa)
RWDD2BRWD domain-containing protein. (319 aa)
ENSRROP00000002977Uncharacterized protein. (245 aa)
ENSRROP00000003282Uncharacterized protein. (148 aa)
NUP37Nucleoporin 37. (326 aa)
LOC104659175Histone H4-like. (101 aa)
SMC3Structural maintenance of chromosomes protein. (1217 aa)
PMLPromyelocytic leukemia. (882 aa)
NUP58Nucleoporin 58. (599 aa)
TPRTranslocated promoter region, nuclear basket protein. (2438 aa)
RELARELA proto-oncogene, NF-kB subunit. (551 aa)
MTA1Metastasis associated 1. (697 aa)
LOC104665118HTH CENPB-type domain-containing protein. (352 aa)
ENSRROP00000004783annotation not available (103 aa)
TIGD6Tigger transposable element derived 6. (521 aa)
TIGD4Tigger transposable element derived 4. (512 aa)
FAM111BFamily with sequence similarity 111 member B. (731 aa)
TIGD1Tigger transposable element derived 1. (591 aa)
SMC6Structural maintenance of chromosomes 6. (1092 aa)
LOC104655509Histone H4. (103 aa)
SUMO1Ubiquitin-like domain-containing protein. (145 aa)
ING1Inhibitor of growth protein. (406 aa)
NUP50Nucleoporin 50. (468 aa)
PGRProgesterone receptor. (917 aa)
HIC2HIC ZBTB transcriptional repressor 2. (615 aa)
ENSRROP00000022479SP-RING-type domain-containing protein. (210 aa)
NSMCE4ANon-structural maintenance of chromosomes element 4; Component of the SMC5-SMC6 complex, that promotes sister chromatid alignment after DNA damage and facilitates double-stranded DNA breaks (DSBs) repair via homologous recombination between sister chromatids. (385 aa)
BMI1RING-type domain-containing protein. (339 aa)
POGKPogo transposable element derived with KRAB domain. (609 aa)
NDC1NDC1 transmembrane nucleoporin. (674 aa)
TOP2ADNA topoisomerase 2; Control of topological states of DNA by transient breakage and subsequent rejoining of DNA strands. Topoisomerase II makes double- strand breaks. (1531 aa)
NUP214Nucleoporin 214. (2090 aa)
DDX5DEAD-box helicase 5; Belongs to the DEAD box helicase family. (614 aa)
CREBBPCREB binding protein. (2442 aa)
DNMT3BUncharacterized protein; Belongs to the class I-like SAM-binding methyltransferase superfamily. C5-methyltransferase family. (853 aa)
LOC104666382Uncharacterized protein. (427 aa)
VHLVon Hippel-Lindau tumor suppressor. (213 aa)
MAGEB6MAGE family member B6. (407 aa)
CTXN2Cortexin 2. (81 aa)
SUMO2-2Small ubiquitin-related modifier. (95 aa)
LOC104666383Histone H4; Core component of nucleosome. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling. (103 aa)
ENSRROP00000001218annotation not available (103 aa)
NUP133Nucleoporin 133. (1156 aa)
MAGEE2MAGE family member E2. (523 aa)
ENSRROP00000001510Uncharacterized protein. (425 aa)
MAGEF1MAGE family member F1. (307 aa)
MDC1Mediator of DNA damage checkpoint 1. (2029 aa)
LOC104663570Histone H4. (103 aa)
HDAC7Histone deacetylase; Responsible for the deacetylation of lysine residues on the N-terminal part of the core histones (H2A, H2B, H3 and H4). Histone deacetylation gives a tag for epigenetic repression and plays an important role in transcriptional regulation, cell cycle progression and developmental events. (1021 aa)
SAFB2Scaffold attachment factor B2. (994 aa)
LOC104663484Histone H4. (103 aa)
ENSRROP00000001958annotation not available (103 aa)
NUP54Nucleoporin 54. (508 aa)
NR4A2Nuclear receptor subfamily 4 group A member 2. (609 aa)
ENSRROP00000021317Protein kinase domain-containing protein; Belongs to the protein kinase superfamily. (374 aa)
UHRF2Ubiquitin like with PHD and ring finger domains 2. (802 aa)
NR3C2Nuclear receptor subfamily 3 group C member 2. (984 aa)
STAG1Stromal antigen 1. (1291 aa)
RNF169Ring finger protein 169. (675 aa)
NFKB2Nuclear factor kappa B subunit 2. (899 aa)
VTCN1V-set domain containing T cell activation inhibitor 1. (285 aa)
LOC104653593Uncharacterized protein. (277 aa)
NUP85Nuclear pore complex protein Nup85; Functions as a component of the nuclear pore complex (NPC). (628 aa)
CFAP53Cilia and flagella associated protein 53. (514 aa)
ZNF350Zinc finger protein 350. (533 aa)
TFAP2ATranscription factor AP-2 alpha. (439 aa)
CASP8AP2Caspase 8 associated protein 2. (1983 aa)
ENSRROP00000019405Hist_deacetyl domain-containing protein. (352 aa)
SUMO2Small ubiquitin-related modifier. (94 aa)
SKOR2c-SKI_SMAD_bind domain-containing protein. (295 aa)
RING1Ring finger protein 1. (406 aa)
ZMIZ1Zinc finger MIZ-type containing 1. (1067 aa)
ZMIZ2Zinc finger MIZ-type containing 2. (886 aa)
DNMT3ADNA methyltransferase 3 alpha; Belongs to the class I-like SAM-binding methyltransferase superfamily. C5-methyltransferase family. (912 aa)
ENSRROP00000018074ULP_PROTEASE domain-containing protein. (566 aa)
RARARetinoic acid receptor alpha. (478 aa)
HDAC2Histone deacetylase 2; Responsible for the deacetylation of lysine residues on the N-terminal part of the core histones (H2A, H2B, H3 and H4). Histone deacetylation gives a tag for epigenetic repression and plays an important role in transcriptional regulation, cell cycle progression and developmental events. Histone deacetylases act via the formation of large multiprotein complexes. (488 aa)
DAXXDaxx domain-containing protein. (744 aa)
CENPBD1CENPB DNA-binding domain containing 1. (170 aa)
POGZPogo transposable element derived with ZNF domain. (1418 aa)
Your Current Organism:
Rhinopithecus roxellana
NCBI taxonomy Id: 61622
Other names: Pygathrix roxellana, R. roxellana, golden snub-nosed monkey
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