STRINGSTRING
PTCH1 PTCH1 ENSRROP00000001260 ENSRROP00000001260 PTCH2 PTCH2 WNT1 WNT1 GNGT1 GNGT1 FZD4 FZD4 FZD8 FZD8 CALCB CALCB FZD5 FZD5 GNG2 GNG2 WNT6 WNT6 WNT2 WNT2 GNGT2 GNGT2 GNB3 GNB3 CRH CRH ENSRROP00000007762 ENSRROP00000007762 VIPR1 VIPR1 CD55 CD55 CRHBP CRHBP GNG7 GNG7 GIP GIP GNG13 GNG13 SMO SMO WNT8A WNT8A CRHR2 CRHR2 GHRHR GHRHR WNT11 WNT11 VIPR2 VIPR2 WNT9A WNT9A GIPR GIPR ADGRE3 ADGRE3 CRHR1 CRHR1 WNT10A WNT10A GNB1 GNB1 WNT5A WNT5A PALMD PALMD SHH SHH WNT16 WNT16 WNT9B WNT9B WNT2B WNT2B SCT SCT FZD6 FZD6 WNT8B WNT8B ADGRE2 ADGRE2 DHH DHH FZD9 FZD9 ENSRROP00000022234 ENSRROP00000022234 VIP VIP PTHLH PTHLH FZD7 FZD7 WNT4 WNT4 FZD2 FZD2 ADGRE5 ADGRE5 ADGRL2 ADGRL2 GLP2R GLP2R GLP1R GLP1R FAP FAP GNG3 GNG3 PTH1R PTH1R PTH2 PTH2 WNT3A WNT3A CALCA CALCA WNT3 WNT3 PTH2R PTH2R ADCYAP1R1 ADCYAP1R1 RAMP1 RAMP1 GNB5 GNB5 GNG4 GNG4 ADM ADM GCG GCG LOC104658087 LOC104658087 ENSRROP00000034142 ENSRROP00000034142 FZD10 FZD10 IAPP IAPP ADGRL1 ADGRL1 GCGR GCGR GNG5 GNG5 GNB4 GNB4 GHRH GHRH ADM2 ADM2 FZD3 FZD3 GNG11 GNG11 GNAS GNAS SCTR SCTR ADCYAP1 ADCYAP1 IHH IHH GNB2 GNB2 RAMP2 RAMP2 GNG12 GNG12 CALCR CALCR WNT7A WNT7A WNT7B WNT7B RAMP3 RAMP3 WNT10B WNT10B PTH PTH GNG8 GNG8 CALCRL CALCRL ADGRL3 ADGRL3 ENSRROP00000045475 ENSRROP00000045475
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
PTCH1Patched 1. (1448 aa)
ENSRROP00000001260Latrophilin domain-containing protein. (184 aa)
PTCH2Patched 2. (1203 aa)
WNT1Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (370 aa)
GNGT1Guanine nucleotide-binding protein subunit gamma; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction. (89 aa)
FZD4Frizzled class receptor 4; Belongs to the G-protein coupled receptor Fz/Smo family. (537 aa)
FZD8Frizzled class receptor 8; Belongs to the G-protein coupled receptor Fz/Smo family. (444 aa)
CALCBCalcitonin related polypeptide beta. (127 aa)
FZD5Frizzled class receptor 5; Belongs to the G-protein coupled receptor Fz/Smo family. (585 aa)
GNG2Guanine nucleotide-binding protein subunit gamma; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction. (110 aa)
WNT6Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (369 aa)
WNT2Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (360 aa)
GNGT2Guanine nucleotide-binding protein subunit gamma; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction. (101 aa)
GNB3G protein subunit beta 3. (340 aa)
CRHCorticotropin releasing hormone. (196 aa)
ENSRROP00000007762Guanine nucleotide-binding protein subunit gamma; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction. (69 aa)
VIPR1Vasoactive intestinal peptide receptor 1; Belongs to the G-protein coupled receptor 2 family. (460 aa)
CD55CD55 molecule (Cromer blood group). (540 aa)
CRHBPCorticotropin-releasing factor-binding protein; Binds CRF and inactivates it. May prevent inappropriate pituitary-adrenal stimulation in pregnancy. Belongs to the CRF-binding protein family. (323 aa)
GNG7Guanine nucleotide-binding protein subunit gamma; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction. (68 aa)
GIPGastric inhibitory polypeptide. (153 aa)
GNG13G protein subunit gamma 13. (67 aa)
SMOSmoothened, frizzled class receptor; Belongs to the G-protein coupled receptor Fz/Smo family. (786 aa)
WNT8AProtein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (351 aa)
CRHR2Corticotropin releasing hormone receptor 2; Belongs to the G-protein coupled receptor 2 family. (431 aa)
GHRHRGrowth hormone releasing hormone receptor; Belongs to the G-protein coupled receptor 2 family. (423 aa)
WNT11Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (354 aa)
VIPR2Vasoactive intestinal peptide receptor 2; Belongs to the G-protein coupled receptor 2 family. (553 aa)
WNT9AProtein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (365 aa)
GIPRGastric inhibitory polypeptide receptor; Belongs to the G-protein coupled receptor 2 family. (466 aa)
ADGRE3Adhesion G protein-coupled receptor E3; Belongs to the G-protein coupled receptor 2 family. (652 aa)
CRHR1Corticotropin releasing hormone receptor 1; Belongs to the G-protein coupled receptor 2 family. (444 aa)
WNT10AProtein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (417 aa)
GNB1G protein subunit beta 1. (340 aa)
WNT5AProtein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (380 aa)
PALMDPalmdelphin. (553 aa)
SHHHH_signal domain-containing protein. (141 aa)
WNT16Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (365 aa)
WNT9BProtein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (357 aa)
WNT2BProtein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (391 aa)
SCTSecretin. (138 aa)
FZD6Frizzled class receptor 6; Belongs to the G-protein coupled receptor Fz/Smo family. (706 aa)
WNT8BProtein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (353 aa)
ADGRE2Adhesion G protein-coupled receptor E2; Belongs to the G-protein coupled receptor 2 family. (816 aa)
DHHHedgehog protein; Intercellular signal essential for a variety of patterning events during development. (396 aa)
FZD9Frizzled class receptor 9; Belongs to the G-protein coupled receptor Fz/Smo family. (510 aa)
ENSRROP00000022234Guanine nucleotide-binding protein subunit gamma; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction. (59 aa)
VIPVasoactive intestinal peptide. (170 aa)
PTHLHParathyroid hormone like hormone. (209 aa)
FZD7Frizzled class receptor 7; Belongs to the G-protein coupled receptor Fz/Smo family. (575 aa)
WNT4Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (345 aa)
FZD2Frizzled class receptor 2; Belongs to the G-protein coupled receptor Fz/Smo family. (571 aa)
ADGRE5Adhesion G protein-coupled receptor E5; Belongs to the G-protein coupled receptor 2 family. (835 aa)
ADGRL2Adhesion G protein-coupled receptor L2; Belongs to the G-protein coupled receptor 2 family. (1482 aa)
GLP2RGlucagon like peptide 2 receptor; Belongs to the G-protein coupled receptor 2 family. (553 aa)
GLP1RGlucagon like peptide 1 receptor; Belongs to the G-protein coupled receptor 2 family. (463 aa)
FAPFibroblast activation protein alpha; Belongs to the peptidase S9B family. (760 aa)
GNG3Guanine nucleotide-binding protein subunit gamma; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction. (75 aa)
PTH1RParathyroid hormone 1 receptor; Belongs to the G-protein coupled receptor 2 family. (593 aa)
PTH2Parathyroid hormone 2. (99 aa)
WNT3AProtein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (352 aa)
CALCACalcitonin related polypeptide alpha. (140 aa)
WNT3Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (355 aa)
PTH2RParathyroid hormone 2 receptor; Belongs to the G-protein coupled receptor 2 family. (550 aa)
ADCYAP1R1ADCYAP receptor type I; Belongs to the G-protein coupled receptor 2 family. (524 aa)
RAMP1Receptor activity modifying protein 1. (148 aa)
GNB5G protein subunit beta 5. (403 aa)
GNG4Guanine nucleotide-binding protein subunit gamma; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction. (75 aa)
ADMAdrenomedullin. (184 aa)
GCGGlucagon. (180 aa)
LOC104658087Uncharacterized protein. (629 aa)
ENSRROP00000034142annotation not available (59 aa)
FZD10Frizzled class receptor 10; Belongs to the G-protein coupled receptor Fz/Smo family. (583 aa)
IAPPIslet amyloid polypeptide. (86 aa)
ADGRL1Adhesion G protein-coupled receptor L1; Belongs to the G-protein coupled receptor 2 family. (1505 aa)
GCGRGlucagon receptor; Belongs to the G-protein coupled receptor 2 family. (484 aa)
GNG5Guanine nucleotide-binding protein subunit gamma; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction. (68 aa)
GNB4G protein subunit beta 4. (340 aa)
GHRHGrowth hormone releasing hormone. (107 aa)
ADM2Adrenomedullin 2. (148 aa)
FZD3Frizzled class receptor 3; Belongs to the G-protein coupled receptor Fz/Smo family. (666 aa)
GNG11Guanine nucleotide-binding protein subunit gamma; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction. (74 aa)
GNASGNAS complex locus. (1041 aa)
SCTRSecretin receptor; Belongs to the G-protein coupled receptor 2 family. (448 aa)
ADCYAP1Adenylate cyclase activating polypeptide 1. (176 aa)
IHHHedgehog protein; Intercellular signal essential for a variety of patterning events during development. (411 aa)
GNB2G protein subunit beta 2. (340 aa)
RAMP2Receptor activity modifying protein 2. (175 aa)
GNG12Guanine nucleotide-binding protein subunit gamma; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction. (72 aa)
CALCRCalcitonin receptor; Belongs to the G-protein coupled receptor 2 family. (489 aa)
WNT7AProtein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (349 aa)
WNT7BProtein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (348 aa)
RAMP3Receptor activity modifying protein 3. (151 aa)
WNT10BProtein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (389 aa)
PTHParathyroid hormone; PTH elevates calcium level by dissolving the salts in bone and preventing their renal excretion; Belongs to the parathyroid hormone family. (115 aa)
GNG8Guanine nucleotide-binding protein subunit gamma; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction. (73 aa)
CALCRLCalcitonin receptor like receptor; Belongs to the G-protein coupled receptor 2 family. (458 aa)
ADGRL3Uncharacterized protein; Belongs to the G-protein coupled receptor 2 family. (647 aa)
ENSRROP00000045475G protein gamma domain-containing protein. (58 aa)
Your Current Organism:
Rhinopithecus roxellana
NCBI taxonomy Id: 61622
Other names: Pygathrix roxellana, R. roxellana, golden snub-nosed monkey
Server load: medium (44%) [HD]