STRINGSTRING
PCSK1 PCSK1 DPP9 DPP9 SPCS2 SPCS2 DPP10 DPP10 GPR119 GPR119 FFAR1 FFAR1 GNB3 GNB3 CDX1 CDX1 TCF7L2 TCF7L2 GNG13 GNG13 CDX4 CDX4 ENSRROP00000016496 ENSRROP00000016496 LEP LEP DPP8 DPP8 GNAT3 GNAT3 DPP6 DPP6 PAX6 PAX6 CDX2 CDX2 FAP FAP CTNNB1 CTNNB1 SEC11A SEC11A GRP GRP SPCS3 SPCS3 GCG GCG SEC11C SEC11C LOC104677425 LOC104677425 DPP4 DPP4 SPCS1 SPCS1 FFAR4 FFAR4
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
PCSK1Proprotein convertase subtilisin/kexin type 1; Belongs to the peptidase S8 family. (749 aa)
DPP9Dipeptidyl peptidase 9; Belongs to the peptidase S9B family. (892 aa)
SPCS2Signal peptidase complex subunit 2. (257 aa)
DPP10Dipeptidyl peptidase like 10; Belongs to the peptidase S9B family. (734 aa)
GPR119G protein-coupled receptor 119; Belongs to the G-protein coupled receptor 1 family. (335 aa)
FFAR1Free fatty acid receptor 1. (300 aa)
GNB3G protein subunit beta 3. (340 aa)
CDX1Caudal type homeobox 1. (154 aa)
TCF7L2Transcription factor 7 like 2. (555 aa)
GNG13G protein subunit gamma 13. (67 aa)
CDX4Caudal type homeobox 4. (280 aa)
ENSRROP00000016496Uncharacterized protein. (188 aa)
LEPLeptin; Key player in the regulation of energy balance and body weight control. Once released into the circulation, has central and peripheral effects by binding LEPR, found in many tissues, which results in the activation of several major signaling pathways. In the hypothalamus, acts as an appetite-regulating factor that induces a decrease in food intake and an increase in energy consumption by inducing anorexinogenic factors and suppressing orexigenic neuropeptides, also regulates bone mass and secretion of hypothalamo- pituitary-adrenal hormones. In the periphery, increases basal me [...] (167 aa)
DPP8Dipeptidyl peptidase 8; Belongs to the peptidase S9B family. (891 aa)
GNAT3Uncharacterized protein. (196 aa)
DPP6Dipeptidyl peptidase like 6; Belongs to the peptidase S9B family. (864 aa)
PAX6Paired box 6. (458 aa)
CDX2Caudal type homeobox 2. (313 aa)
FAPFibroblast activation protein alpha; Belongs to the peptidase S9B family. (760 aa)
CTNNB1Catenin beta 1. (781 aa)
SEC11ASignal peptidase complex catalytic subunit SEC11. (187 aa)
GRPGastrin releasing peptide. (162 aa)
SPCS3Signal peptidase complex subunit 3. (180 aa)
GCGGlucagon. (180 aa)
SEC11CSignal peptidase complex catalytic subunit SEC11. (192 aa)
LOC104677425Uncharacterized protein. (157 aa)
DPP4Dipeptidyl peptidase 4; Belongs to the peptidase S9B family. (766 aa)
SPCS1Signal peptidase complex subunit 1. (169 aa)
FFAR4Free fatty acid receptor 4. (377 aa)
Your Current Organism:
Rhinopithecus roxellana
NCBI taxonomy Id: 61622
Other names: Pygathrix roxellana, R. roxellana, golden snub-nosed monkey
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