STRINGSTRING
GNG12 GNG12 XRN2 XRN2 CSNK2B CSNK2B FBXO4 FBXO4 TUBA4A TUBA4A ENSRROP00000044486 ENSRROP00000044486 GNG8 GNG8 PFDN2 PFDN2 FBXW7 FBXW7 TCP1 TCP1 ENSRROP00000045475 ENSRROP00000045475 VBP1 VBP1 FBXL5 FBXL5 RGS7 RGS7 GNB2 GNB2 PFDN6 PFDN6 ARFGEF2 ARFGEF2 TUBA1B TUBA1B ARFGEF1 ARFGEF1 GNG11 GNG11 FBXW2 FBXW2 CSNK2A1 CSNK2A1 ERMARD ERMARD PFDN5 PFDN5 FBXO6 FBXO6 DCAF7 DCAF7 ENSRROP00000036732 ENSRROP00000036732 TUBA1C TUBA1C TUBAL3 TUBAL3 LOC104665543 LOC104665543 GNB4 GNB4 ENSRROP00000036051 ENSRROP00000036051 FBXW9 FBXW9 ENSRROP00000035890 ENSRROP00000035890 GNAQ GNAQ GNG5 GNG5 RGS6 RGS6 ENSRROP00000034142 ENSRROP00000034142 TUBB6 TUBB6 TBCA TBCA PFDN1 PFDN1 GNG4 GNG4 CCT5 CCT5 FBXL3 FBXL3 PDCL PDCL ENSRROP00000031519 ENSRROP00000031519 GNB5 GNB5 LOC104656714 LOC104656714 ENSRROP00000031129 ENSRROP00000031129 GBA GBA KIF13A KIF13A ENSRROP00000029454 ENSRROP00000029454 FBXW4 FBXW4 CCT6A CCT6A CCT3 CCT3 TP53 TP53 GNG3 GNG3 GNA14 GNA14 FBXW10 FBXW10 SKIV2L SKIV2L USP11 USP11 TBCB TBCB GNA15 GNA15 LOC104676693 LOC104676693 ENSRROP00000022234 ENSRROP00000022234 RGS9 RGS9 CCT4 CCT4 FBXO44 FBXO44 LOC104658704 LOC104658704 STAT3 STAT3 LOC104673637 LOC104673637 FKBP9 FKBP9 TBCD TBCD CCNE2 CCNE2 ENSRROP00000017642 ENSRROP00000017642 WRAP53 WRAP53 AP3M2 AP3M2 GNA11 GNA11 TUBA3D TUBA3D CCNE1 CCNE1 PDC PDC CSNK2A2 CSNK2A2 GNB1 GNB1 SPHK1 SPHK1 CCT7 CCT7 CCT6B CCT6B PFDN4 PFDN4 CCT8 CCT8 KIFC3 KIFC3 RGS11 RGS11 AP3M1 AP3M1 GNG13 GNG13 TUBB1 TUBB1 FBXW5 FBXW5 GNG7 GNG7 GAPDHS GAPDHS CCT2 CCT2 ACTB ACTB ENSRROP00000007762 ENSRROP00000007762 LOC104661226 LOC104661226 ENSRROP00000007230 ENSRROP00000007230 TBCC TBCC LONP2 LONP2 HDAC3 HDAC3 TUBA8 TUBA8 LOC104660088 LOC104660088 GNB3 GNB3 ENSRROP00000005474 ENSRROP00000005474 ENSRROP00000005469 ENSRROP00000005469 GNGT2 GNGT2 NOP56 NOP56 ARL2 ARL2 ENSRROP00000003774 ENSRROP00000003774 GNG2 GNG2 TBCE TBCE GNGT1 GNGT1 ENSRROP00000002176 ENSRROP00000002176 ENSRROP00000000970 ENSRROP00000000970 TUBA1A TUBA1A FKBP10 FKBP10 ENSRROP00000041636 ENSRROP00000041636
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
GNG12Guanine nucleotide-binding protein subunit gamma; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction. (72 aa)
XRN25'-3' exoribonuclease; Possesses 5'->3' exoribonuclease activity. May promote termination of transcription by RNA polymerase II. (1063 aa)
CSNK2BUncharacterized protein. (298 aa)
FBXO4F-box protein 4. (387 aa)
TUBA4ATubulin alpha chain; Tubulin is the major constituent of microtubules. It binds two moles of GTP, one at an exchangeable site on the beta chain and one at a non-exchangeable site on the alpha chain. (448 aa)
ENSRROP00000044486Uncharacterized protein. (108 aa)
GNG8Guanine nucleotide-binding protein subunit gamma; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction. (73 aa)
PFDN2Prefoldin subunit 2. (154 aa)
FBXW7F-box and WD repeat domain containing 7. (707 aa)
TCP1Uncharacterized protein. (555 aa)
ENSRROP00000045475G protein gamma domain-containing protein. (58 aa)
VBP1Prefoldin subunit 3; Binds specifically to cytosolic chaperonin (c-CPN) and transfers target proteins to it. Binds to nascent polypeptide chain and promotes folding in an environment in which there are many competing pathways for nonnative proteins; Belongs to the prefoldin subunit alpha family. (197 aa)
FBXL5F-box and leucine rich repeat protein 5. (691 aa)
RGS7Regulator of G protein signaling 7. (487 aa)
GNB2G protein subunit beta 2. (340 aa)
PFDN6Prefoldin subunit 6. (129 aa)
ARFGEF2ADP ribosylation factor guanine nucleotide exchange factor 2. (1785 aa)
TUBA1BTubulin alpha chain; Tubulin is the major constituent of microtubules. It binds two moles of GTP, one at an exchangeable site on the beta chain and one at a non-exchangeable site on the alpha chain. (453 aa)
ARFGEF1ADP ribosylation factor guanine nucleotide exchange factor 1. (1817 aa)
GNG11Guanine nucleotide-binding protein subunit gamma; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction. (74 aa)
FBXW2Uncharacterized protein. (454 aa)
CSNK2A1Protein kinase domain-containing protein; Belongs to the protein kinase superfamily. (391 aa)
ERMARDER membrane associated RNA degradation. (688 aa)
PFDN5Uncharacterized protein. (160 aa)
FBXO6F-box protein 6. (293 aa)
DCAF7DDB1 and CUL4 associated factor 7. (342 aa)
ENSRROP00000036732Tubulin domain-containing protein. (96 aa)
TUBA1CTubulin alpha chain; Tubulin is the major constituent of microtubules. It binds two moles of GTP, one at an exchangeable site on the beta chain and one at a non-exchangeable site on the alpha chain. (489 aa)
TUBAL3Tubulin alpha chain; Tubulin is the major constituent of microtubules. It binds two moles of GTP, one at an exchangeable site on the beta chain and one at a non-exchangeable site on the alpha chain. (446 aa)
LOC104665543Uncharacterized protein. (507 aa)
GNB4G protein subunit beta 4. (340 aa)
ENSRROP00000036051Tubulin-specific chaperone A; Belongs to the TBCA family. (92 aa)
FBXW9F-box and WD repeat domain containing 9. (485 aa)
ENSRROP00000035890G protein gamma domain-containing protein. (68 aa)
GNAQG protein subunit alpha q. (359 aa)
GNG5Guanine nucleotide-binding protein subunit gamma; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction. (68 aa)
RGS6Regulator of G protein signaling 6. (538 aa)
ENSRROP00000034142annotation not available (59 aa)
TUBB6Tubulin beta chain; Tubulin is the major constituent of microtubules. It binds two moles of GTP, one at an exchangeable site on the beta chain and one at a non-exchangeable site on the alpha chain. Belongs to the tubulin family. (374 aa)
TBCATubulin-specific chaperone A; Belongs to the TBCA family. (131 aa)
PFDN1Prefoldin subunit 1. (127 aa)
GNG4Guanine nucleotide-binding protein subunit gamma; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction. (75 aa)
CCT5Chaperonin containing TCP1 subunit 5. (541 aa)
FBXL3F-box and leucine rich repeat protein 3. (428 aa)
PDCLPhosducin like. (301 aa)
ENSRROP00000031519Tubulin alpha chain; Tubulin is the major constituent of microtubules. It binds two moles of GTP, one at an exchangeable site on the beta chain and one at a non-exchangeable site on the alpha chain. (351 aa)
GNB5G protein subunit beta 5. (403 aa)
LOC104656714Uncharacterized protein. (172 aa)
ENSRROP00000031129Tubulin domain-containing protein. (114 aa)
GBAGlucosylceramidase. (533 aa)
KIF13AKinesin family member 13A; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family. (1839 aa)
ENSRROP00000029454Uncharacterized protein. (444 aa)
FBXW4F-box and WD repeat domain containing 4. (411 aa)
CCT6AUncharacterized protein. (531 aa)
CCT3T-complex protein 1 subunit gamma. (545 aa)
TP53Cellular tumor antigen p53; Acts as a tumor suppressor in many tumor types; induces growth arrest or apoptosis depending on the physiological circumstances and cell type. Involved in cell cycle regulation as a trans-activator that acts to negatively regulate cell division by controlling a set of genes required for this process. One of the activated genes is an inhibitor of cyclin-dependent kinases. Apoptosis induction seems to be mediated either by stimulation of BAX and FAS antigen expression, or by repression of Bcl-2 expression; Belongs to the p53 family. (393 aa)
GNG3Guanine nucleotide-binding protein subunit gamma; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction. (75 aa)
GNA14G protein subunit alpha 14. (355 aa)
FBXW10WD_REPEATS_REGION domain-containing protein. (1048 aa)
SKIV2LSki2 like RNA helicase. (1250 aa)
USP11Ubiquitin carboxyl-terminal hydrolase; Deubiquitinating enzyme that removes conjugated ubiquitin from specific proteins to regulate different cellular processes. Belongs to the peptidase C19 family. (976 aa)
TBCBTubulin folding cofactor B. (244 aa)
GNA15G protein subunit alpha 15. (374 aa)
LOC104676693Uncharacterized protein. (538 aa)
ENSRROP00000022234Guanine nucleotide-binding protein subunit gamma; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction. (59 aa)
RGS9Regulator of G protein signaling 9. (674 aa)
CCT4T-complex protein 1 subunit delta. (597 aa)
FBXO44Uncharacterized protein. (255 aa)
LOC104658704Uncharacterized protein. (519 aa)
STAT3Signal transducer and activator of transcription. (802 aa)
LOC104673637Uncharacterized protein. (113 aa)
FKBP9Peptidylprolyl isomerase. (623 aa)
TBCDTubulin folding cofactor D. (1230 aa)
CCNE2Cyclin E2; Belongs to the cyclin family. (404 aa)
ENSRROP00000017642Glucosylceramidase. (376 aa)
WRAP53WD repeat containing antisense to TP53. (549 aa)
AP3M2AP-3 complex subunit mu-2. (418 aa)
GNA11G protein subunit alpha 11. (359 aa)
TUBA3DTubulin alpha chain; Tubulin is the major constituent of microtubules. It binds two moles of GTP, one at an exchangeable site on the beta chain and one at a non-exchangeable site on the alpha chain. (459 aa)
CCNE1Cyclin E1; Belongs to the cyclin family. (410 aa)
PDCPhosducin. (194 aa)
CSNK2A2Casein kinase 2 alpha 2; Belongs to the protein kinase superfamily. (350 aa)
GNB1G protein subunit beta 1. (340 aa)
SPHK1Sphingosine kinase 1. (472 aa)
CCT7T-complex protein 1 subunit eta; Molecular chaperone; assists the folding of proteins upon ATP hydrolysis. Known to play a role, in vitro, in the folding of actin and tubulin. (543 aa)
CCT6BChaperonin containing TCP1 subunit 6B. (531 aa)
PFDN4Prefoldin subunit 4; Binds specifically to cytosolic chaperonin (c-CPN) and transfers target proteins to it. Binds to nascent polypeptide chain and promotes folding in an environment in which there are many competing pathways for nonnative proteins; Belongs to the prefoldin subunit beta family. (134 aa)
CCT8Chaperonin containing TCP1 subunit 8. (553 aa)
KIFC3Kinesin-like protein; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family. (858 aa)
RGS11Regulator of G protein signaling 11. (467 aa)
AP3M1AP-3 complex subunit mu-1; Part of the AP-3 complex, an adaptor-related complex which is not clathrin-associated. The complex is associated with the Golgi region as well as more peripheral structures. It facilitates the budding of vesicles from the Golgi membrane and may be directly involved in trafficking to lysosomes; Belongs to the adaptor complexes medium subunit family. (468 aa)
GNG13G protein subunit gamma 13. (67 aa)
TUBB1Tubulin beta chain; Tubulin is the major constituent of microtubules. It binds two moles of GTP, one at an exchangeable site on the beta chain and one at a non-exchangeable site on the alpha chain. (451 aa)
FBXW5F-box and WD repeat domain containing 5. (566 aa)
GNG7Guanine nucleotide-binding protein subunit gamma; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction. (68 aa)
GAPDHSGlyceraldehyde-3-phosphate dehydrogenase. (392 aa)
CCT2Chaperonin containing TCP1 subunit 2. (535 aa)
ACTBActin beta. (375 aa)
ENSRROP00000007762Guanine nucleotide-binding protein subunit gamma; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction. (69 aa)
LOC104661226Tubulin beta chain; Tubulin is the major constituent of microtubules. It binds two moles of GTP, one at an exchangeable site on the beta chain and one at a non-exchangeable site on the alpha chain. Belongs to the tubulin family. (441 aa)
ENSRROP00000007230Uncharacterized protein. (193 aa)
TBCCTubulin folding cofactor C. (377 aa)
LONP2Lon protease homolog 2, peroxisomal; ATP-dependent serine protease that mediates the selective degradation of misfolded and unassembled polypeptides in the peroxisomal matrix. Necessary for type 2 peroxisome targeting signal (PTS2)-containing protein processing and facilitates peroxisome matrix protein import. May indirectly regulate peroxisomal fatty acid beta- oxidation through degradation of the self-processed forms of TYSND1. (852 aa)
HDAC3Histone deacetylase 3; Responsible for the deacetylation of lysine residues on the N-terminal part of the core histones (H2A, H2B, H3 and H4), and some other non-histone substrates. Histone deacetylation gives a tag for epigenetic repression and plays an important role in transcriptional regulation, cell cycle progression and developmental events. Histone deacetylases act via the formation of large multiprotein complexes. (428 aa)
TUBA8Tubulin alpha chain; Tubulin is the major constituent of microtubules. It binds two moles of GTP, one at an exchangeable site on the beta chain and one at a non-exchangeable site on the alpha chain. (454 aa)
LOC104660088T-complex protein 1 subunit eta; Molecular chaperone; assists the folding of proteins upon ATP hydrolysis. Known to play a role, in vitro, in the folding of actin and tubulin. (491 aa)
GNB3G protein subunit beta 3. (340 aa)
ENSRROP00000005474Uncharacterized protein. (495 aa)
ENSRROP00000005469Uncharacterized protein. (53 aa)
GNGT2Guanine nucleotide-binding protein subunit gamma; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction. (101 aa)
NOP56NOP56 ribonucleoprotein. (594 aa)
ARL2Uncharacterized protein; Belongs to the small GTPase superfamily. Arf family. (184 aa)
ENSRROP00000003774Uncharacterized protein. (423 aa)
GNG2Guanine nucleotide-binding protein subunit gamma; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction. (110 aa)
TBCECAP-Gly domain-containing protein. (578 aa)
GNGT1Guanine nucleotide-binding protein subunit gamma; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction. (89 aa)
ENSRROP00000002176Uncharacterized protein; Belongs to the small GTPase superfamily. Arf family. (179 aa)
ENSRROP00000000970Uncharacterized protein; Belongs to the TCP-1 chaperonin family. (114 aa)
TUBA1ATubulin alpha chain; Tubulin is the major constituent of microtubules. It binds two moles of GTP, one at an exchangeable site on the beta chain and one at a non-exchangeable site on the alpha chain. (451 aa)
FKBP10Peptidylprolyl isomerase. (582 aa)
ENSRROP00000041636T-complex protein 1 subunit delta. (456 aa)
Your Current Organism:
Rhinopithecus roxellana
NCBI taxonomy Id: 61622
Other names: Pygathrix roxellana, R. roxellana, golden snub-nosed monkey
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