STRINGSTRING
PPP2R5A PPP2R5A REEP3 REEP3 ORAI3 ORAI3 LOC104655958 LOC104655958 KCNMB4 KCNMB4 ITPR2 ITPR2 PTGIR PTGIR PPP2CA PPP2CA TRPC6 TRPC6 MAPK14 MAPK14 GNG3 GNG3 GUCY1B1 GUCY1B1 ENSRROP00000028974 ENSRROP00000028974 PTPN6 PTPN6 PDE5A PDE5A ATP2B1 ATP2B1 SLC8A3 SLC8A3 ENSRROP00000007762 ENSRROP00000007762 SLC8A1 SLC8A1 PDE11A PDE11A GNG7 GNG7 ENSRROP00000010437 ENSRROP00000010437 GNG13 GNG13 NOS1 NOS1 ENSRROP00000011759 ENSRROP00000011759 ORAI2 ORAI2 PLA2G4A PLA2G4A ENSRROP00000013107 ENSRROP00000013107 PPP2CB PPP2CB GNB1 GNB1 PTPN11 PTPN11 REEP2 REEP2 TRPC7 TRPC7 KCNMB2 KCNMB2 PRKG2 PRKG2 KCNMA1 KCNMA1 REEP4 REEP4 ENSRROP00000016415 ENSRROP00000016415 ENSRROP00000017001 ENSRROP00000017001 PPP2R1B PPP2R1B ATP2B2 ATP2B2 LRP8 LRP8 STIM1 STIM1 NOS3 NOS3 ENSRROP00000021422 ENSRROP00000021422 PDE10A PDE10A APOB APOB PDE1A PDE1A ENSRROP00000022234 ENSRROP00000022234 ENSRROP00000022655 ENSRROP00000022655 ENSRROP00000045475 ENSRROP00000045475 SLC8A2 SLC8A2 GNG8 GNG8 ENSRROP00000044392 ENSRROP00000044392 ITPR1 ITPR1 ATP2A2 ATP2A2 GNG12 GNG12 ENSRROP00000042123 ENSRROP00000042123 ENSRROP00000042109 ENSRROP00000042109 PAFAH2 PAFAH2 P2RX6 P2RX6 PRKG1 PRKG1 ATP2B3 ATP2B3 GNB2 GNB2 ENSRROP00000039493 ENSRROP00000039493 MRVI1 MRVI1 GNAS GNAS GNG11 GNG11 PPP2R5C PPP2R5C PPP2R5B PPP2R5B PDE2A PDE2A P2RX4 P2RX4 PPP2R5D PPP2R5D ENSRROP00000036200 ENSRROP00000036200 GNB4 GNB4 ITPR3 ITPR3 P2RX2 P2RX2 GNG5 GNG5 PDE1B PDE1B PDE9A PDE9A ENSRROP00000034722 ENSRROP00000034722 ENSRROP00000034142 ENSRROP00000034142 FGR FGR GNG4 GNG4 MED4-2 MED4-2 GNB5 GNB5 TRPC3 TRPC3 PPP2R1A PPP2R1A P2RX3 P2RX3 ATP2A3 ATP2A3 P2RX1 P2RX1 SRI SRI GNB3 GNB3 ENSRROP00000006154 ENSRROP00000006154 PECAM1 PECAM1 GNGT2 GNGT2 GUCY1A1 GUCY1A1 PPP2R5E PPP2R5E ATP2A1 ATP2A1 GNG2 GNG2 NOS2 NOS2 ATP2B4 ATP2B4 ORAI1 ORAI1 GNGT1 GNGT1 P2RX7 P2RX7
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
PPP2R5ASerine/threonine-protein phosphatase 2A 56 kDa regulatory subunit; The B regulatory subunit might modulate substrate selectivity and catalytic activity, and also might direct the localization of the catalytic enzyme to a particular subcellular compartment. (486 aa)
REEP3Receptor expression-enhancing protein. (249 aa)
ORAI3ORAI calcium release-activated calcium modulator 3. (295 aa)
LOC104655958Uncharacterized protein. (423 aa)
KCNMB4Potassium calcium-activated channel subfamily M regulatory beta subunit 4. (210 aa)
ITPR2Inositol 1,4,5-trisphosphate receptor type 2. (2700 aa)
PTGIRProstaglandin I2 receptor. (386 aa)
PPP2CASerine/threonine-protein phosphatase. (309 aa)
TRPC6Uncharacterized protein; Belongs to the transient receptor (TC 1.A.4) family. (931 aa)
MAPK14Mitogen-activated protein kinase. (360 aa)
GNG3Guanine nucleotide-binding protein subunit gamma; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction. (75 aa)
GUCY1B1Guanylate cyclase 1 soluble subunit beta 1; Belongs to the adenylyl cyclase class-4/guanylyl cyclase family. (642 aa)
ENSRROP00000028974Uncharacterized protein. (71 aa)
PTPN6Tyrosine-protein phosphatase non-receptor type; Belongs to the protein-tyrosine phosphatase family. Non- receptor class 2 subfamily. (623 aa)
PDE5APhosphodiesterase. (875 aa)
ATP2B1Calcium-transporting ATPase; This magnesium-dependent enzyme catalyzes the hydrolysis of ATP coupled with the transport of calcium. (1249 aa)
SLC8A3Solute carrier family 8 member A3; Belongs to the Ca(2+):cation antiporter (CaCA) (TC 2.A.19) family. (928 aa)
ENSRROP00000007762Guanine nucleotide-binding protein subunit gamma; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction. (69 aa)
SLC8A1Solute carrier family 8 member A1; Belongs to the Ca(2+):cation antiporter (CaCA) (TC 2.A.19) family. (973 aa)
PDE11APhosphodiesterase. (933 aa)
GNG7Guanine nucleotide-binding protein subunit gamma; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction. (68 aa)
ENSRROP00000010437Uncharacterized protein. (235 aa)
GNG13G protein subunit gamma 13. (67 aa)
NOS1Nitric oxide synthase; Produces nitric oxide (NO). (1184 aa)
ENSRROP00000011759Uncharacterized protein. (274 aa)
ORAI2ORAI calcium release-activated calcium modulator 2. (262 aa)
PLA2G4APhospholipase A2. (749 aa)
ENSRROP00000013107Uncharacterized protein. (128 aa)
PPP2CBSerine/threonine-protein phosphatase. (312 aa)
GNB1G protein subunit beta 1. (340 aa)
PTPN11Tyrosine-protein phosphatase non-receptor type; Belongs to the protein-tyrosine phosphatase family. Non- receptor class 2 subfamily. (593 aa)
REEP2Receptor expression-enhancing protein. (254 aa)
TRPC7Transient receptor potential cation channel subfamily C member 7; Belongs to the transient receptor (TC 1.A.4) family. (862 aa)
KCNMB2Uncharacterized protein. (216 aa)
PRKG2cGMP-dependent protein kinase. (762 aa)
KCNMA1Potassium calcium-activated channel subfamily M alpha 1. (1285 aa)
REEP4Receptor expression-enhancing protein. (257 aa)
ENSRROP00000016415XRCC1_N domain-containing protein. (142 aa)
ENSRROP00000017001Uncharacterized protein. (369 aa)
PPP2R1BProtein phosphatase 2 scaffold subunit Abeta. (667 aa)
ATP2B2Calcium-transporting ATPase; This magnesium-dependent enzyme catalyzes the hydrolysis of ATP coupled with the transport of calcium. (1270 aa)
LRP8LDL receptor related protein 8. (959 aa)
STIM1Stromal interaction molecule 1. (785 aa)
NOS3Nitric oxide synthase; Produces nitric oxide (NO). (1205 aa)
ENSRROP00000021422Uncharacterized protein. (534 aa)
PDE10APhosphodiesterase. (715 aa)
APOBApolipoprotein B. (4555 aa)
PDE1APhosphodiesterase. (544 aa)
ENSRROP00000022234Guanine nucleotide-binding protein subunit gamma; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction. (59 aa)
ENSRROP00000022655P2X purinoceptor; Receptor for ATP that acts as a ligand-gated ion channel. Belongs to the P2X receptor family. (357 aa)
ENSRROP00000045475G protein gamma domain-containing protein. (58 aa)
SLC8A2Solute carrier family 8 member A2; Belongs to the Ca(2+):cation antiporter (CaCA) (TC 2.A.19) family. (921 aa)
GNG8Guanine nucleotide-binding protein subunit gamma; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction. (73 aa)
ENSRROP00000044392Uncharacterized protein. (440 aa)
ITPR1Inositol 1,4,5-trisphosphate receptor type 1. (2714 aa)
ATP2A2Calcium-transporting ATPase; This magnesium-dependent enzyme catalyzes the hydrolysis of ATP coupled with the transport of calcium. (1042 aa)
GNG12Guanine nucleotide-binding protein subunit gamma; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction. (72 aa)
ENSRROP00000042123Uncharacterized protein. (251 aa)
ENSRROP00000042109Uncharacterized protein. (3227 aa)
PAFAH2Platelet-activating factor acetylhydrolase. (413 aa)
P2RX6P2X purinoceptor; Receptor for ATP that acts as a ligand-gated ion channel. (407 aa)
PRKG1Protein kinase cGMP-dependent 1; Belongs to the protein kinase superfamily. (463 aa)
ATP2B3Calcium-transporting ATPase; This magnesium-dependent enzyme catalyzes the hydrolysis of ATP coupled with the transport of calcium. (1220 aa)
GNB2G protein subunit beta 2. (340 aa)
ENSRROP00000039493Uncharacterized protein; Belongs to the transient receptor (TC 1.A.4) family. (814 aa)
MRVI1Murine retrovirus integration site 1 homolog. (911 aa)
GNASGNAS complex locus. (1041 aa)
GNG11Guanine nucleotide-binding protein subunit gamma; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction. (74 aa)
PPP2R5CSerine/threonine-protein phosphatase 2A 56 kDa regulatory subunit; The B regulatory subunit might modulate substrate selectivity and catalytic activity, and also might direct the localization of the catalytic enzyme to a particular subcellular compartment. (579 aa)
PPP2R5BSerine/threonine-protein phosphatase 2A 56 kDa regulatory subunit; The B regulatory subunit might modulate substrate selectivity and catalytic activity, and also might direct the localization of the catalytic enzyme to a particular subcellular compartment. (596 aa)
PDE2APhosphodiesterase. (941 aa)
P2RX4P2X purinoceptor; Receptor for ATP that acts as a ligand-gated ion channel. (404 aa)
PPP2R5DSerine/threonine-protein phosphatase 2A 56 kDa regulatory subunit; The B regulatory subunit might modulate substrate selectivity and catalytic activity, and also might direct the localization of the catalytic enzyme to a particular subcellular compartment. (605 aa)
ENSRROP00000036200Uncharacterized protein. (491 aa)
GNB4G protein subunit beta 4. (340 aa)
ITPR3Inositol 1,4,5-trisphosphate receptor type 3. (2703 aa)
P2RX2P2X purinoceptor; Receptor for ATP that acts as a ligand-gated ion channel. (395 aa)
GNG5Guanine nucleotide-binding protein subunit gamma; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction. (68 aa)
PDE1BPhosphodiesterase. (564 aa)
PDE9APhosphodiesterase. (593 aa)
ENSRROP00000034722Uncharacterized protein. (107 aa)
ENSRROP00000034142annotation not available (59 aa)
FGRTyrosine-protein kinase. (529 aa)
GNG4Guanine nucleotide-binding protein subunit gamma; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction. (75 aa)
MED4-2Mediator of RNA polymerase II transcription subunit 4; Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene- specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors. (178 aa)
GNB5G protein subunit beta 5. (403 aa)
TRPC3Transient receptor potential cation channel subfamily C member 3; Belongs to the transient receptor (TC 1.A.4) family. (921 aa)
PPP2R1AProtein phosphatase 2 scaffold subunit Aalpha. (589 aa)
P2RX3P2X purinoceptor; Receptor for ATP that acts as a ligand-gated ion channel. (398 aa)
ATP2A3Calcium-transporting ATPase; This magnesium-dependent enzyme catalyzes the hydrolysis of ATP coupled with the transport of calcium. (1027 aa)
P2RX1P2X purinoceptor; Receptor for ATP that acts as a ligand-gated ion channel. (399 aa)
SRISorcin. (198 aa)
GNB3G protein subunit beta 3. (340 aa)
ENSRROP00000006154Uncharacterized protein. (163 aa)
PECAM1Platelet and endothelial cell adhesion molecule 1. (756 aa)
GNGT2Guanine nucleotide-binding protein subunit gamma; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction. (101 aa)
GUCY1A1Guanylate cyclase 1 soluble subunit alpha 1; Belongs to the adenylyl cyclase class-4/guanylyl cyclase family. (690 aa)
PPP2R5ESerine/threonine-protein phosphatase 2A 56 kDa regulatory subunit; The B regulatory subunit might modulate substrate selectivity and catalytic activity, and also might direct the localization of the catalytic enzyme to a particular subcellular compartment. (467 aa)
ATP2A1Calcium-transporting ATPase; This magnesium-dependent enzyme catalyzes the hydrolysis of ATP coupled with the transport of calcium. (1027 aa)
GNG2Guanine nucleotide-binding protein subunit gamma; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction. (110 aa)
NOS2Nitric oxide synthase; Produces nitric oxide (NO). (1153 aa)
ATP2B4Calcium-transporting ATPase; This magnesium-dependent enzyme catalyzes the hydrolysis of ATP coupled with the transport of calcium. (1205 aa)
ORAI1ORAI calcium release-activated calcium modulator 1. (300 aa)
GNGT1Guanine nucleotide-binding protein subunit gamma; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction. (89 aa)
P2RX7P2X purinoceptor; Receptor for ATP that acts as a ligand-gated ion channel. Belongs to the P2X receptor family. (595 aa)
Your Current Organism:
Rhinopithecus roxellana
NCBI taxonomy Id: 61622
Other names: Pygathrix roxellana, R. roxellana, golden snub-nosed monkey
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