STRINGSTRING
KCNB1 KCNB1 GNB5 GNB5 GNG4 GNG4 THAP7 THAP7 GCG GCG ENSRROP00000034142 ENSRROP00000034142 INS INS CACNA1F CACNA1F CACNB3 CACNB3 GNG5 GNG5 GNAQ GNAQ ITPR3 ITPR3 ENSRROP00000035890 ENSRROP00000035890 PRKAR2B PRKAR2B GNB4 GNB4 SNAP25 SNAP25 PRKAR2A PRKAR2A GNG11 GNG11 GNAS GNAS RAP1A RAP1A GNB2 GNB2 PLCB3 PLCB3 ENSRROP00000019238 ENSRROP00000019238 PRKAR1B PRKAR1B GNA11 GNA11 GNB1 GNB1 RAPGEF3 RAPGEF3 CACNB2 CACNB2 CACNA2D2 CACNA2D2 RAPGEFL1 RAPGEFL1 CACNA1E CACNA1E VAMP2 VAMP2 PRKACA PRKACA GNG13 GNG13 GNAI2 GNAI2 ABCC8 ABCC8 GNG7 GNG7 KCNC2 KCNC2 STX1A STX1A ENSRROP00000007762 ENSRROP00000007762 KCNJ11 KCNJ11 GNB3 GNB3 CD36 CD36 RAPGEF4 RAPGEF4 PRKACB PRKACB GNGT2 GNGT2 FFAR1 FFAR1 AKAP5 AKAP5 PLCB2 PLCB2 ADCY5 ADCY5 GNG2 GNG2 STXBP1 STXBP1 ACSL3 ACSL3 GNGT1 GNGT1 ADCY6 ADCY6 GNG12 GNG12 PRKCA PRKCA ITPR1 ITPR1 GNG8 GNG8 ENSRROP00000045475 ENSRROP00000045475 ADCY8 ADCY8 KCNS3 KCNS3 SLC2A2 SLC2A2 AHCYL1 AHCYL1 PRKAR1A PRKAR1A ACSL4 ACSL4 GNA14 GNA14 FAP FAP GNG3 GNG3 SLC2A1 SLC2A1 CACNA1A CACNA1A RAPGEF5 RAPGEF5 GLP1R GLP1R IQGAP1 IQGAP1 GNA15 GNA15 CACNA1D CACNA1D ITPR2 ITPR2 KCNG2 KCNG2 PLCB1 PLCB1 ENSRROP00000022234 ENSRROP00000022234 MARCKS MARCKS THAP6 THAP6 SYT5 SYT5 CACNA1C CACNA1C CACNA2D1 CACNA2D1
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
KCNB1Potassium voltage-gated channel subfamily B member 1; Belongs to the potassium channel family. (858 aa)
GNB5G protein subunit beta 5. (403 aa)
GNG4Guanine nucleotide-binding protein subunit gamma; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction. (75 aa)
THAP7THAP domain containing 7. (309 aa)
GCGGlucagon. (180 aa)
ENSRROP00000034142annotation not available (59 aa)
INSInsulin; Insulin decreases blood glucose concentration. It increases cell permeability to monosaccharides, amino acids and fatty acids. It accelerates glycolysis, the pentose phosphate cycle, and glycogen synthesis in liver. (110 aa)
CACNA1FVoltage-dependent L-type calcium channel subunit alpha; Voltage-sensitive calcium channels (VSCC) mediate the entry of calcium ions into excitable cells and are also involved in a variety of calcium-dependent processes, including muscle contraction, hormone or neurotransmitter release, gene expression, cell motility, cell division and cell death; Belongs to the calcium channel alpha-1 subunit (TC 1.A.1.11) family. (1971 aa)
CACNB3Calcium voltage-gated channel auxiliary subunit beta 3. (485 aa)
GNG5Guanine nucleotide-binding protein subunit gamma; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction. (68 aa)
GNAQG protein subunit alpha q. (359 aa)
ITPR3Inositol 1,4,5-trisphosphate receptor type 3. (2703 aa)
ENSRROP00000035890G protein gamma domain-containing protein. (68 aa)
PRKAR2BProtein kinase cAMP-dependent type II regulatory subunit beta. (429 aa)
GNB4G protein subunit beta 4. (340 aa)
SNAP25Synaptosomal-associated protein; Belongs to the SNAP-25 family. (206 aa)
PRKAR2AProtein kinase cAMP-dependent type II regulatory subunit alpha. (404 aa)
GNG11Guanine nucleotide-binding protein subunit gamma; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction. (74 aa)
GNASGNAS complex locus. (1041 aa)
RAP1ARAP1A, member of RAS oncogene family. (184 aa)
GNB2G protein subunit beta 2. (340 aa)
PLCB31-phosphatidylinositol 4,5-bisphosphate phosphodiesterase; The production of the second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3) is mediated by activated phosphatidylinositol-specific phospholipase C enzymes. (1234 aa)
ENSRROP00000019238Voltage-dependent L-type calcium channel subunit alpha; Voltage-sensitive calcium channels (VSCC) mediate the entry of calcium ions into excitable cells and are also involved in a variety of calcium-dependent processes, including muscle contraction, hormone or neurotransmitter release, gene expression, cell motility, cell division and cell death; Belongs to the calcium channel alpha-1 subunit (TC 1.A.1.11) family. (785 aa)
PRKAR1BProtein kinase cAMP-dependent type I regulatory subunit beta. (381 aa)
GNA11G protein subunit alpha 11. (359 aa)
GNB1G protein subunit beta 1. (340 aa)
RAPGEF3Rap guanine nucleotide exchange factor 3. (923 aa)
CACNB2Calcium voltage-gated channel auxiliary subunit beta 2. (660 aa)
CACNA2D2Calcium voltage-gated channel auxiliary subunit alpha2delta 2. (1124 aa)
RAPGEFL1Rap guanine nucleotide exchange factor like 1. (669 aa)
CACNA1EVoltage-dependent R-type calcium channel subunit alpha; Voltage-sensitive calcium channels (VSCC) mediate the entry of calcium ions into excitable cells and are also involved in a variety of calcium-dependent processes, including muscle contraction, hormone or neurotransmitter release, gene expression, cell motility, cell division and cell death. The isoform alpha-1E gives rise to R-type calcium currents. (2313 aa)
VAMP2V-SNARE coiled-coil homology domain-containing protein. (193 aa)
PRKACAProtein kinase cAMP-activated catalytic subunit alpha; Belongs to the protein kinase superfamily. (351 aa)
GNG13G protein subunit gamma 13. (67 aa)
GNAI2G protein subunit alpha i2. (355 aa)
ABCC8ATP binding cassette subfamily C member 8. (1585 aa)
GNG7Guanine nucleotide-binding protein subunit gamma; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction. (68 aa)
KCNC2Potassium voltage-gated channel subfamily C member 2; Belongs to the potassium channel family. (638 aa)
STX1ASyntaxin 1A; Belongs to the syntaxin family. (289 aa)
ENSRROP00000007762Guanine nucleotide-binding protein subunit gamma; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction. (69 aa)
KCNJ11Potassium voltage-gated channel subfamily J member 11. (390 aa)
GNB3G protein subunit beta 3. (340 aa)
CD36CD36 molecule; Belongs to the CD36 family. (472 aa)
RAPGEF4Rap guanine nucleotide exchange factor 4. (1011 aa)
PRKACBProtein kinase cAMP-activated catalytic subunit beta; Belongs to the protein kinase superfamily. (398 aa)
GNGT2Guanine nucleotide-binding protein subunit gamma; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction. (101 aa)
FFAR1Free fatty acid receptor 1. (300 aa)
AKAP5A-kinase anchoring protein 5. (427 aa)
PLCB21-phosphatidylinositol 4,5-bisphosphate phosphodiesterase; The production of the second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3) is mediated by activated phosphatidylinositol-specific phospholipase C enzymes. (1162 aa)
ADCY5Adenylate cyclase 5; Belongs to the adenylyl cyclase class-4/guanylyl cyclase family. (864 aa)
GNG2Guanine nucleotide-binding protein subunit gamma; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction. (110 aa)
STXBP1Syntaxin binding protein 1; Belongs to the STXBP/unc-18/SEC1 family. (603 aa)
ACSL3Acyl-CoA synthetase long chain family member 3. (720 aa)
GNGT1Guanine nucleotide-binding protein subunit gamma; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction. (89 aa)
ADCY6Adenylate cyclase 6; Belongs to the adenylyl cyclase class-4/guanylyl cyclase family. (603 aa)
GNG12Guanine nucleotide-binding protein subunit gamma; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction. (72 aa)
PRKCAProtein kinase C; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. PKC subfamily. (672 aa)
ITPR1Inositol 1,4,5-trisphosphate receptor type 1. (2714 aa)
GNG8Guanine nucleotide-binding protein subunit gamma; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction. (73 aa)
ENSRROP00000045475G protein gamma domain-containing protein. (58 aa)
ADCY8Adenylate cyclase type 8; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling. (1043 aa)
KCNS3Potassium voltage-gated channel modifier subfamily S member 3; Belongs to the potassium channel family. (491 aa)
SLC2A2Solute carrier family 2 member 2; Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family. (524 aa)
AHCYL1Adenosylhomocysteinase like 1; Belongs to the adenosylhomocysteinase family. (530 aa)
PRKAR1AProtein kinase cAMP-dependent type I regulatory subunit alpha. (381 aa)
ACSL4Acyl-CoA synthetase long chain family member 4. (711 aa)
GNA14G protein subunit alpha 14. (355 aa)
FAPFibroblast activation protein alpha; Belongs to the peptidase S9B family. (760 aa)
GNG3Guanine nucleotide-binding protein subunit gamma; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction. (75 aa)
SLC2A1Solute carrier family 2 member 1; Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family. (506 aa)
CACNA1AVoltage-dependent P/Q-type calcium channel subunit alpha; Voltage-sensitive calcium channels (VSCC) mediate the entry of calcium ions into excitable cells and are also involved in a variety of calcium-dependent processes, including muscle contraction, hormone or neurotransmitter release, gene expression, cell motility, cell division and cell death. The isoform alpha-1A gives rise to P and/or Q- type calcium currents. (2426 aa)
RAPGEF5Rap guanine nucleotide exchange factor 5. (730 aa)
GLP1RGlucagon like peptide 1 receptor; Belongs to the G-protein coupled receptor 2 family. (463 aa)
IQGAP1IQ motif containing GTPase activating protein 1. (1696 aa)
GNA15G protein subunit alpha 15. (374 aa)
CACNA1DVoltage-dependent L-type calcium channel subunit alpha; Voltage-sensitive calcium channels (VSCC) mediate the entry of calcium ions into excitable cells and are also involved in a variety of calcium-dependent processes, including muscle contraction, hormone or neurotransmitter release, gene expression, cell motility, cell division and cell death; Belongs to the calcium channel alpha-1 subunit (TC 1.A.1.11) family. (2181 aa)
ITPR2Inositol 1,4,5-trisphosphate receptor type 2. (2700 aa)
KCNG2Potassium voltage-gated channel modifier subfamily G member 2; Belongs to the potassium channel family. (378 aa)
PLCB11-phosphatidylinositol 4,5-bisphosphate phosphodiesterase; The production of the second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3) is mediated by activated phosphatidylinositol-specific phospholipase C enzymes. (1114 aa)
ENSRROP00000022234Guanine nucleotide-binding protein subunit gamma; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction. (59 aa)
MARCKSMyristoylated alanine rich protein kinase C substrate. (285 aa)
THAP6THAP domain containing 6. (222 aa)
SYT5Synaptotagmin 5. (386 aa)
CACNA1CCa_chan_IQ domain-containing protein. (829 aa)
CACNA2D1Calcium voltage-gated channel auxiliary subunit alpha2delta 1. (1103 aa)
Your Current Organism:
Rhinopithecus roxellana
NCBI taxonomy Id: 61622
Other names: Pygathrix roxellana, R. roxellana, golden snub-nosed monkey
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