STRINGSTRING
HSP90AA1 HSP90AA1 CTNNA1 CTNNA1 LOC104655302 LOC104655302 ITGAV ITGAV AKT1 AKT1 ACTL7B ACTL7B PXN PXN PDPK1 PDPK1 DOCK1 DOCK1 PRR5 PRR5 WASF2 WASF2 SHD SHD ENSRROP00000004479 ENSRROP00000004479 ENSRROP00000004872 ENSRROP00000004872 ACTRT1 ACTRT1 RNF222 RNF222 PRKACB PRKACB NCKAP1L NCKAP1L MAPKAP1 MAPKAP1 ACTL7A ACTL7A PAK2 PAK2 PIK3R2 PIK3R2 HSH2D HSH2D NCK2 NCK2 WASF1 WASF1 SHF SHF ACTB ACTB THEM4 THEM4 ENSRROP00000009442 ENSRROP00000009442 ABI1 ABI1 STX7 STX7 ACTG1 ACTG1 PRKACA PRKACA PIK3CA PIK3CA PRKCD PRKCD LOC104682584 LOC104682584 VAV1 VAV1 STX12 STX12 ENSRROP00000013905 ENSRROP00000013905 VAV2 VAV2 CYBB CYBB SPHK1 SPHK1 ENSRROP00000015288 ENSRROP00000015288 RHOA RHOA BCAR1 BCAR1 ENSRROP00000015769 ENSRROP00000015769 MLST8 MLST8 CYFIP1 CYFIP1 NRAS NRAS MAPKAPK3 MAPKAPK3 FYN FYN SH2D2A SH2D2A ENSRROP00000019483 ENSRROP00000019483 LOC104658196 LOC104658196 SRC SRC PRKCB PRKCB NOS3 NOS3 AKT3 AKT3 LOC104681622 LOC104681622 PIK3R1 PIK3R1 RASA1 RASA1 ROCK2 ROCK2 VAV3 VAV3 ENSRROP00000022705 ENSRROP00000022705 ENSRROP00000022735 ENSRROP00000022735 FNDC3A FNDC3A ITGB3 ITGB3 ITPR2 ITPR2 CRK CRK LOC104675682 LOC104675682 JUP JUP ENSRROP00000024190 ENSRROP00000024190 CAV1 CAV1 KDR KDR PLCG1 PLCG1 LPXN LPXN MTOR MTOR MAPK14 MAPK14 BRK1 BRK1 ENSRROP00000026135 ENSRROP00000026135 AHCYL1 AHCYL1 NCF1 NCF1 FNDC3B FNDC3B TGFB1I1 TGFB1I1 RICTOR RICTOR ACTL8 ACTL8 AXL AXL ERAS ERAS NEDD9 NEDD9 MAPKAPK2 MAPKAPK2 MAPK12 MAPK12 CTNNB1 CTNNB1 CYFIP2 CYFIP2 HSPB1 HSPB1 WASF3 WASF3 PTK2 PTK2 KRAS KRAS NCF4 NCF4 SHE SHE ABI2 ABI2 SHB SHB CDC42 CDC42 HRAS HRAS ITPR3 ITPR3 CYBA CYBA ELMO1 ELMO1 ENSRROP00000036642 ENSRROP00000036642 CASS4 CASS4 ARVCF ARVCF MAPK13 MAPK13 PRKCZ PRKCZ PTK2B PTK2B CSDE1 CSDE1 ELMO2 ELMO2 AKT2 AKT2 BAIAP2 BAIAP2 ROCK1 ROCK1 VEGFA VEGFA NCF2 NCF2 PRKCA PRKCA NCK1 NCK1 NCKAP1 NCKAP1 MAPK11 MAPK11 PIK3CB PIK3CB CDH5 CDH5 ELMO3 ELMO3 ITPR1 ITPR1 CTNND1 CTNND1 ENSRROP00000044328 ENSRROP00000044328 PAK1 PAK1 TRIB3 TRIB3 EFS EFS ENSRROP00000045019 ENSRROP00000045019 ENSRROP00000045515 ENSRROP00000045515
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
HSP90AA1HATPase_c domain-containing protein. (657 aa)
CTNNA1Catenin alpha 1. (906 aa)
LOC104655302SHSP domain-containing protein; Belongs to the small heat shock protein (HSP20) family. (205 aa)
ITGAVIntegrin subunit alpha V; Belongs to the integrin alpha chain family. (1048 aa)
AKT1Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily. (480 aa)
ACTL7BActin like 7B; Belongs to the actin family. (415 aa)
PXNPaxillin. (1082 aa)
PDPK13-phosphoinositide dependent protein kinase 1. (356 aa)
DOCK1Dedicator of cytokinesis 1; Belongs to the DOCK family. (1870 aa)
PRR5Proline rich 5. (410 aa)
WASF2WASP family member 2. (498 aa)
SHDSrc homology 2 domain containing transforming protein D. (340 aa)
ENSRROP00000004479Uncharacterized protein. (191 aa)
ENSRROP00000004872Protein kinase domain-containing protein; Belongs to the protein kinase superfamily. (275 aa)
ACTRT1Actin related protein T1; Belongs to the actin family. (375 aa)
RNF222Ring finger protein 222. (220 aa)
PRKACBProtein kinase cAMP-activated catalytic subunit beta; Belongs to the protein kinase superfamily. (398 aa)
NCKAP1LNCK associated protein 1 like. (1134 aa)
MAPKAP1MAPK associated protein 1. (522 aa)
ACTL7AActin like 7A; Belongs to the actin family. (435 aa)
PAK2Non-specific serine/threonine protein kinase. (524 aa)
PIK3R2Uncharacterized protein. (647 aa)
HSH2DHematopoietic SH2 domain containing. (352 aa)
NCK2Cytoplasmic protein. (382 aa)
WASF1WASP family member 1. (559 aa)
SHFSrc homology 2 domain containing F. (421 aa)
ACTBActin beta. (375 aa)
THEM4Thioesterase superfamily member 4. (265 aa)
ENSRROP00000009442Uncharacterized protein. (179 aa)
ABI1Abl interactor 1. (508 aa)
STX7Syntaxin 7; Belongs to the syntaxin family. (261 aa)
ACTG1Actin gamma 1. (375 aa)
PRKACAProtein kinase cAMP-activated catalytic subunit alpha; Belongs to the protein kinase superfamily. (351 aa)
PIK3CAPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit. (1068 aa)
PRKCDProtein kinase C delta type; Calcium-independent, phospholipid- and diacylglycerol (DAG)- dependent serine/threonine-protein kinase that plays contrasting roles in cell death and cell survival by functioning as a pro-apoptotic protein during DNA damage-induced apoptosis, but acting as an anti- apoptotic protein during cytokine receptor-initiated cell death, is involved in tumor suppression; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. PKC subfamily. (676 aa)
LOC104682584HATPase_c domain-containing protein. (674 aa)
VAV1Vav guanine nucleotide exchange factor 1. (845 aa)
STX12Syntaxin 12; Belongs to the syntaxin family. (276 aa)
ENSRROP00000013905Uncharacterized protein. (135 aa)
VAV2Vav guanine nucleotide exchange factor 2. (810 aa)
CYBBCytochrome b-245 beta chain. (570 aa)
SPHK1Sphingosine kinase 1. (472 aa)
ENSRROP00000015288DH domain-containing protein. (263 aa)
RHOARas homolog family member A. (193 aa)
BCAR1BCAR1 scaffold protein, Cas family member. (916 aa)
ENSRROP00000015769Uncharacterized protein. (279 aa)
MLST8MTOR associated protein, LST8 homolog. (335 aa)
CYFIP1Cytoplasmic FMR1-interacting protein; Belongs to the CYFIP family. (1253 aa)
NRASNRAS proto-oncogene, GTPase. (189 aa)
MAPKAPK3MAPK activated protein kinase 3; Belongs to the protein kinase superfamily. (434 aa)
FYNTyrosine-protein kinase. (537 aa)
SH2D2ASH2 domain containing 2A. (389 aa)
ENSRROP00000019483Uncharacterized protein; Belongs to the actin family. (316 aa)
LOC104658196CRIB domain-containing protein. (176 aa)
SRCTyrosine-protein kinase. (540 aa)
PRKCBNon-specific serine/threonine protein kinase. (590 aa)
NOS3Nitric oxide synthase; Produces nitric oxide (NO). (1205 aa)
AKT3Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily. (479 aa)
LOC104681622Uncharacterized protein; Belongs to the actin family. (244 aa)
PIK3R1Phosphoinositide-3-kinase regulatory subunit 1. (724 aa)
RASA1RAS p21 protein activator 1. (1047 aa)
ROCK2Rho-associated protein kinase; Protein kinase which is a key regulator of actin cytoskeleton and cell polarity. (1383 aa)
VAV3Uncharacterized protein. (287 aa)
ENSRROP00000022705Uncharacterized protein. (377 aa)
ENSRROP00000022735Uncharacterized protein. (370 aa)
FNDC3AFibronectin type III domain containing 3A. (1198 aa)
ITGB3Integrin beta; Belongs to the integrin beta chain family. (788 aa)
ITPR2Inositol 1,4,5-trisphosphate receptor type 2. (2700 aa)
CRKCRK proto-oncogene, adaptor protein. (304 aa)
LOC104675682HATPase_c domain-containing protein. (671 aa)
JUPJunction plakoglobin. (760 aa)
ENSRROP00000024190Protein kinase domain-containing protein. (137 aa)
CAV1Caveolin; May act as a scaffolding protein within caveolar membranes. Interacts directly with G-protein alpha subunits and can functionally regulate their activity; Belongs to the caveolin family. (147 aa)
KDRKinase insert domain receptor; Belongs to the protein kinase superfamily. Tyr protein kinase family. CSF-1/PDGF receptor subfamily. (1356 aa)
PLCG11-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma; Mediates the production of the second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3). Plays an important role in the regulation of intracellular signaling cascades. (1303 aa)
LPXNLeupaxin; Transcriptional coactivator for androgen receptor (AR) and serum response factor (SRF). Contributes to the regulation of cell adhesion, spreading and cell migration and acts as a negative regulator in integrin-mediated cell adhesion events. Suppresses the integrin- induced tyrosine phosphorylation of paxillin (PXN). (386 aa)
MTORSerine/threonine-protein kinase mTOR; Belongs to the PI3/PI4-kinase family. (2549 aa)
MAPK14Mitogen-activated protein kinase. (360 aa)
BRK1BRICK1 subunit of SCAR/WAVE actin nucleating complex. (75 aa)
ENSRROP00000026135Uncharacterized protein. (384 aa)
AHCYL1Adenosylhomocysteinase like 1; Belongs to the adenosylhomocysteinase family. (530 aa)
NCF1Neutrophil cytosolic factor 1. (390 aa)
FNDC3BFibronectin type III domain containing 3B. (1204 aa)
TGFB1I1Transforming growth factor beta-1-induced transcript 1 protein; Functions as a molecular adapter coordinating multiple protein-protein interactions at the focal adhesion complex and in the nucleus. Links various intracellular signaling modules to plasma membrane receptors and regulates the Wnt and TGFB signaling pathways. (456 aa)
RICTORRPTOR independent companion of MTOR complex 2. (1695 aa)
ACTL8Actin like 8; Belongs to the actin family. (366 aa)
AXLAXL receptor tyrosine kinase. (894 aa)
ERASES cell expressed Ras. (233 aa)
NEDD9Neural precursor cell expressed, developmentally down-regulated 9. (834 aa)
MAPKAPK2MAPK activated protein kinase 2. (322 aa)
MAPK12Mitogen-activated protein kinase. (367 aa)
CTNNB1Catenin beta 1. (781 aa)
CYFIP2Cytoplasmic FMR1-interacting protein; Belongs to the CYFIP family. (1278 aa)
HSPB1SHSP domain-containing protein; Belongs to the small heat shock protein (HSP20) family. (205 aa)
WASF3WASP family member 3. (502 aa)
PTK2Protein tyrosine kinase 2; Belongs to the protein kinase superfamily. Tyr protein kinase family. (1109 aa)
KRASKRAS proto-oncogene, GTPase. (189 aa)
NCF4Neutrophil cytosolic factor 4. (339 aa)
SHESrc homology 2 domain containing E. (520 aa)
ABI2Abl interactor 2. (513 aa)
SHBSH2 domain containing adaptor protein B. (509 aa)
CDC42Uncharacterized protein. (191 aa)
HRASHRas proto-oncogene, GTPase. (189 aa)
ITPR3Inositol 1,4,5-trisphosphate receptor type 3. (2703 aa)
CYBACytochrome b-245 light chain; Critical component of the membrane-bound oxidase of phagocytes that generates superoxide. Associates with NOX3 to form a functional NADPH oxidase constitutively generating superoxide. (194 aa)
ELMO1Engulfment and cell motility 1. (727 aa)
ENSRROP00000036642Phorbol-ester/DAG-type domain-containing protein. (57 aa)
CASS4Cas scaffold protein family member 4. (786 aa)
ARVCFARVCF delta catenin family member. (962 aa)
MAPK13Mitogen-activated protein kinase. (401 aa)
PRKCZProtein kinase C; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. PKC subfamily. (582 aa)
PTK2BProtein tyrosine kinase 2 beta; Belongs to the protein kinase superfamily. Tyr protein kinase family. (1058 aa)
CSDE1Cold shock domain containing E1. (844 aa)
ELMO2Engulfment and cell motility 2. (726 aa)
AKT2Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily. (481 aa)
BAIAP2BAI1 associated protein 2. (532 aa)
ROCK1Rho-associated protein kinase; Protein kinase which is a key regulator of actin cytoskeleton and cell polarity. (1368 aa)
VEGFAVascular endothelial growth factor A; Belongs to the PDGF/VEGF growth factor family. (395 aa)
NCF2Neutrophil cytosolic factor 2. (526 aa)
PRKCAProtein kinase C; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. PKC subfamily. (672 aa)
NCK1Cytoplasmic protein. (377 aa)
NCKAP1NCK associated protein 1. (1123 aa)
MAPK11Mitogen-activated protein kinase. (339 aa)
PIK3CBPhosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit beta; Belongs to the PI3/PI4-kinase family. (1073 aa)
CDH5Cadherin 5; Cadherins are calcium-dependent cell adhesion proteins. (784 aa)
ELMO3Engulfment and cell motility 3. (774 aa)
ITPR1Inositol 1,4,5-trisphosphate receptor type 1. (2714 aa)
CTNND1Catenin delta 1. (971 aa)
ENSRROP00000044328Uncharacterized protein. (184 aa)
PAK1Non-specific serine/threonine protein kinase. (555 aa)
TRIB3Tribbles pseudokinase 3. (385 aa)
EFSEmbryonal Fyn-associated substrate. (561 aa)
ENSRROP00000045019Uncharacterized protein. (182 aa)
ENSRROP00000045515Uncharacterized protein. (185 aa)
Your Current Organism:
Rhinopithecus roxellana
NCBI taxonomy Id: 61622
Other names: Pygathrix roxellana, R. roxellana, golden snub-nosed monkey
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