STRINGSTRING
SUV39H1 SUV39H1 H2BC3 H2BC3 POLR1C POLR1C LOC104681099 LOC104681099 DNMT3B DNMT3B ENSRROP00000000351 ENSRROP00000000351 HIST1H3I HIST1H3I LOC104674022 LOC104674022 SAP30 SAP30 ENSRROP00000000734 ENSRROP00000000734 H2AX H2AX LOC104678627 LOC104678627 LOC104666383 LOC104666383 ENSRROP00000001218 ENSRROP00000001218 LOC104667440 LOC104667440 LOC104663440 LOC104663440 LOC104663570 LOC104663570 LOC104663484 LOC104663484 LOC104670865 LOC104670865 ENSRROP00000001958 ENSRROP00000001958 H3C15 H3C15 ENSRROP00000002615 ENSRROP00000002615 LOC104658131 LOC104658131 LOC104663490 LOC104663490 LOC104659175 LOC104659175 LOC104663563 LOC104663563 H2AC4 H2AC4 LOC104676331 LOC104676331 LOC104670102 LOC104670102 LOC104669800 LOC104669800 LOC104654619 LOC104654619 LOC104663742 LOC104663742 ENSRROP00000004411 ENSRROP00000004411 LOC104663458 LOC104663458 H2BC14 H2BC14 POLR2F POLR2F ENSRROP00000004783 ENSRROP00000004783 LOC104663503 LOC104663503 LOC104655509 LOC104655509 LOC104663575 LOC104663575 ENSRROP00000005396 ENSRROP00000005396 LOC104663468 LOC104663468 LOC104663425 LOC104663425 LOC104666728 LOC104666728 LOC104663512 LOC104663512 H2BC5 H2BC5 H2AC20 H2AC20 LOC104670855 LOC104670855 H2BU1 H2BU1 LOC104663473 LOC104663473 ENSRROP00000006359 ENSRROP00000006359 H2BC11 H2BC11 LOC104676512 LOC104676512 ENSRROP00000006448 ENSRROP00000006448 ENSRROP00000045253 ENSRROP00000045253 POLR2L POLR2L GTF2H4 GTF2H4 RRP8 RRP8 ARID4B ARID4B SIN3A SIN3A H2BC15 H2BC15 ENSRROP00000042387 ENSRROP00000042387 GTF2H1 GTF2H1 POLR2K POLR2K POLR2E POLR2E H3F3B H3F3B CD3EAP CD3EAP ENSRROP00000037563 ENSRROP00000037563 TTF1 TTF1 SUDS3 SUDS3 BAZ2A BAZ2A SAP30BP SAP30BP SIN3B SIN3B ENSRROP00000034241 ENSRROP00000034241 POLR1E POLR1E ERCC3 ERCC3 CDK7 CDK7 POLR2H POLR2H ERCC2 ERCC2 TWISTNB TWISTNB ENSRROP00000032892 ENSRROP00000032892 H2AZ1 H2AZ1 GTF2H2 GTF2H2 TAF1C TAF1C MNAT1 MNAT1 ENSRROP00000023339 ENSRROP00000023339 POLR1B POLR1B CCNH CCNH UBTF UBTF SIRT1 SIRT1 MBD2 MBD2 SMARCA1 SMARCA1 ENSRROP00000020266 ENSRROP00000020266 BAZ2B BAZ2B H3F3A H3F3A ENSRROP00000019405 ENSRROP00000019405 ENSRROP00000018014 ENSRROP00000018014 H2AZ2 H2AZ2 HDAC2 HDAC2 TAF1A TAF1A SAP130 SAP130 GTF2H5 GTF2H5 DNMT1 DNMT1 LOC104672561 LOC104672561 ZNRD1 ZNRD1 LOC104677352 LOC104677352 LOC104659463 LOC104659463 TBP TBP ENSRROP00000026238 ENSRROP00000026238 LOC104659226 LOC104659226 TAF1D TAF1D SAP30L SAP30L ENSRROP00000006684 ENSRROP00000006684 H2AJ H2AJ H2AC6 H2AC6 LOC104663449 LOC104663449 LOC104663505 LOC104663505 ENSRROP00000007615 ENSRROP00000007615 LOC104680836 LOC104680836 LOC104661665 LOC104661665 GTF2H3 GTF2H3 SMARCA5 SMARCA5 SAP18 SAP18 POLR1A POLR1A HDAC1 HDAC1
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
SUV39H1Histone-lysine N-methyltransferase; Belongs to the class V-like SAM-binding methyltransferase superfamily. Histone-lysine methyltransferase family. Suvar3-9 subfamily. (423 aa)
H2BC3Histone H2B; Belongs to the histone H2B family. (126 aa)
POLR1CRNA polymerase I and III subunit C. (350 aa)
LOC104681099Histone H2B; Belongs to the histone H2B family. (126 aa)
DNMT3BUncharacterized protein; Belongs to the class I-like SAM-binding methyltransferase superfamily. C5-methyltransferase family. (853 aa)
ENSRROP00000000351Uncharacterized protein. (67 aa)
HIST1H3IHistone H3; Belongs to the histone H3 family. (136 aa)
LOC104674022Histone H3; Belongs to the histone H3 family. (136 aa)
SAP30Sin3A associated protein 30. (124 aa)
ENSRROP00000000734annotation not available (136 aa)
H2AXHistone H2A; Belongs to the histone H2A family. (143 aa)
LOC104678627Histone H3; Belongs to the histone H3 family. (136 aa)
LOC104666383Histone H4; Core component of nucleosome. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling. (103 aa)
ENSRROP00000001218annotation not available (103 aa)
LOC104667440Histone H3; Belongs to the histone H3 family. (136 aa)
LOC104663440Histone H2B; Belongs to the histone H2B family. (126 aa)
LOC104663570Histone H4. (103 aa)
LOC104663484Histone H4. (103 aa)
LOC104670865Histone H3.1. (136 aa)
ENSRROP00000001958annotation not available (103 aa)
H3C15Histone H3; Belongs to the histone H3 family. (136 aa)
ENSRROP00000002615annotation not available (103 aa)
LOC104658131Histone H3.3. (136 aa)
LOC104663490Histone H3.1. (136 aa)
LOC104659175Histone H4-like. (101 aa)
LOC104663563Histone H3.1. (136 aa)
H2AC4Histone H2A; Belongs to the histone H2A family. (130 aa)
LOC104676331Histone H3.3. (136 aa)
LOC104670102Histone H3. (136 aa)
LOC104669800Histone H3.3. (136 aa)
LOC104654619Histone H3.3. (136 aa)
LOC104663742Histone H2B; Belongs to the histone H2B family. (127 aa)
ENSRROP00000004411annotation not available (136 aa)
LOC104663458Histone H2B type 1. (126 aa)
H2BC14Histone H2B; Belongs to the histone H2B family. (126 aa)
POLR2FRNA polymerase II subunit F. (150 aa)
ENSRROP00000004783annotation not available (103 aa)
LOC104663503Histone H3-like. (136 aa)
LOC104655509Histone H4. (103 aa)
LOC104663575Histone H3.1. (136 aa)
ENSRROP00000005396annotation not available (103 aa)
LOC104663468Histone H2A type 1. (130 aa)
LOC104663425Histone H3.1. (136 aa)
LOC104666728Histone H2B; Belongs to the histone H2B family. (126 aa)
LOC104663512Histone H2B type 1. (126 aa)
H2BC5Histone H2B; Belongs to the histone H2B family. (126 aa)
H2AC20Histone H2A; Belongs to the histone H2A family. (129 aa)
LOC104670855Histone H2B; Belongs to the histone H2B family. (126 aa)
H2BU1Histone H2B; Belongs to the histone H2B family. (126 aa)
LOC104663473Histone H3.1. (136 aa)
ENSRROP00000006359annotation not available (103 aa)
H2BC11Histone H2B; Belongs to the histone H2B family. (126 aa)
LOC104676512Histone H3; Belongs to the histone H3 family. (136 aa)
ENSRROP00000006448Histone domain-containing protein. (141 aa)
ENSRROP00000045253Histone H2A; Belongs to the histone H2A family. (131 aa)
POLR2LRNA polymerase II subunit L. (67 aa)
GTF2H4General transcription factor IIH subunit 4; Component of the general transcription and DNA repair factor IIH (TFIIH) core complex which is involved in general and transcription-coupled nucleotide excision repair (NER) of damaged DNA. Belongs to the TFB2 family. (462 aa)
RRP8Ribosomal RNA-processing protein 8; Essential component of the eNoSC (energy-dependent nucleolar silencing) complex, a complex that mediates silencing of rDNA in response to intracellular energy status and acts by recruiting histone- modifying enzymes. The eNoSC complex is able to sense the energy status of cell: upon glucose starvation, elevation of NAD(+)/NADP(+) ratio activates SIRT1, leading to histone H3 deacetylation followed by dimethylation of H3 at 'Lys-9' (H3K9me2) by SUV39H1 and the formation of silent chromatin in the rDNA locus. In the complex, RRP8 binds to H3K9me2 and pr [...] (468 aa)
ARID4BAT-rich interaction domain 4B. (1314 aa)
SIN3ASIN3 transcription regulator family member A. (1273 aa)
H2BC15Histone H2B; Belongs to the histone H2B family. (166 aa)
ENSRROP00000042387BAH domain-containing protein; Belongs to the class I-like SAM-binding methyltransferase superfamily. C5-methyltransferase family. (691 aa)
GTF2H1General transcription factor IIH subunit 1. (557 aa)
POLR2KRNA polymerase II subunit K. (58 aa)
POLR2ERNA polymerase II subunit E. (210 aa)
H3F3BH3 histone, family 3B. (136 aa)
CD3EAPCD3e molecule associated protein. (512 aa)
ENSRROP00000037563Histone H3; Belongs to the histone H3 family. (141 aa)
TTF1Transcription termination factor 1. (880 aa)
SUDS3SDS3 homolog, SIN3A corepressor complex component. (328 aa)
BAZ2ABromodomain adjacent to zinc finger domain 2A. (1909 aa)
SAP30BPSAP30 binding protein. (308 aa)
SIN3BSIN3 transcription regulator family member B. (1164 aa)
ENSRROP00000034241Histone H2B; Belongs to the histone H2B family. (129 aa)
POLR1ERNA polymerase I subunit E. (419 aa)
ERCC3ERCC excision repair 3, TFIIH core complex helicase subunit. (782 aa)
CDK7Cyclin dependent kinase 7; Belongs to the protein kinase superfamily. (346 aa)
POLR2HRNA polymerase II subunit H. (174 aa)
ERCC2ERCC excision repair 2, TFIIH core complex helicase subunit. (760 aa)
TWISTNBTWIST neighbor. (338 aa)
ENSRROP00000032892Histone H2B; Belongs to the histone H2B family. (136 aa)
H2AZ1Histone H2A; Belongs to the histone H2A family. (128 aa)
GTF2H2General transcription factor IIH subunit. (395 aa)
TAF1CTATA-box binding protein associated factor, RNA polymerase I subunit C. (843 aa)
MNAT1CDK-activating kinase assembly factor MAT1; Stabilizes the cyclin H-CDK7 complex to form a functional CDK-activating kinase (CAK) enzymatic complex. (309 aa)
ENSRROP00000023339Histone H2A; Belongs to the histone H2A family. (125 aa)
POLR1BUncharacterized protein. (76 aa)
CCNHCyclin H; Belongs to the cyclin family. (325 aa)
UBTFUpstream binding transcription factor. (764 aa)
SIRT1Sirtuin 1. (746 aa)
MBD2Methyl-CpG binding domain protein 2. (319 aa)
SMARCA1SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 1. (1070 aa)
ENSRROP00000020266Histone H2B; Belongs to the histone H2B family. (134 aa)
BAZ2BBromodomain adjacent to zinc finger domain 2B. (2212 aa)
H3F3AH3 histone, family 3A. (136 aa)
ENSRROP00000019405Hist_deacetyl domain-containing protein. (352 aa)
ENSRROP00000018014Protein kinase domain-containing protein. (315 aa)
H2AZ2Histone H2A; Belongs to the histone H2A family. (128 aa)
HDAC2Histone deacetylase 2; Responsible for the deacetylation of lysine residues on the N-terminal part of the core histones (H2A, H2B, H3 and H4). Histone deacetylation gives a tag for epigenetic repression and plays an important role in transcriptional regulation, cell cycle progression and developmental events. Histone deacetylases act via the formation of large multiprotein complexes. (488 aa)
TAF1ATATA-box binding protein associated factor, RNA polymerase I subunit A. (451 aa)
SAP130Sin3A associated protein 130. (1083 aa)
GTF2H5General transcription factor IIH subunit 5. (71 aa)
DNMT1DNA (cytosine-5)-methyltransferase; Belongs to the class I-like SAM-binding methyltransferase superfamily. C5-methyltransferase family. (1665 aa)
LOC104672561Histone H3. (136 aa)
ZNRD1DNA-directed RNA polymerase subunit; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. Belongs to the archaeal rpoM/eukaryotic RPA12/RPB9/RPC11 RNA polymerase family. (126 aa)
LOC104677352Histone deacetylase 1; Responsible for the deacetylation of lysine residues on the N-terminal part of the core histones (H2A, H2B, H3 and H4). Histone deacetylation gives a tag for epigenetic repression and plays an important role in transcriptional regulation, cell cycle progression and developmental events. Histone deacetylases act via the formation of large multiprotein complexes. (484 aa)
LOC104659463Histone H2B type 1-A. (127 aa)
TBPTATA-box binding protein. (333 aa)
ENSRROP00000026238Uncharacterized protein. (71 aa)
LOC104659226Histone H4. (103 aa)
TAF1DTATA-box binding protein associated factor, RNA polymerase I subunit D. (278 aa)
SAP30LSAP30 like. (188 aa)
ENSRROP00000006684annotation not available (103 aa)
H2AJHistone H2A; Belongs to the histone H2A family. (129 aa)
H2AC6Histone H2A; Belongs to the histone H2A family. (130 aa)
LOC104663449Histone H4. (103 aa)
LOC104663505Histone H2B type 1. (126 aa)
ENSRROP00000007615Uncharacterized protein. (466 aa)
LOC104680836Histone domain-containing protein. (136 aa)
LOC104661665Histone H3.3. (136 aa)
GTF2H3General transcription factor IIH subunit 3. (308 aa)
SMARCA5SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 5. (1044 aa)
SAP18Sin3A associated protein 18. (172 aa)
POLR1ADNA-directed RNA polymerase subunit; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. (1754 aa)
HDAC1Histone deacetylase 1; Responsible for the deacetylation of lysine residues on the N-terminal part of the core histones (H2A, H2B, H3 and H4). Histone deacetylation gives a tag for epigenetic repression and plays an important role in transcriptional regulation, cell cycle progression and developmental events. Histone deacetylases act via the formation of large multiprotein complexes. (477 aa)
Your Current Organism:
Rhinopithecus roxellana
NCBI taxonomy Id: 61622
Other names: Pygathrix roxellana, R. roxellana, golden snub-nosed monkey
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