STRINGSTRING
VWA5B2 VWA5B2 DDB2 DDB2 GTF2H4 GTF2H4 ENSRROP00000044797 ENSRROP00000044797 VWA5B1 VWA5B1 ENSRROP00000043101 ENSRROP00000043101 POLD2 POLD2 GTF2H1 GTF2H1 LOC104664457 LOC104664457 KCTD2 KCTD2 UBE2I UBE2I RAD23B RAD23B ERCC1 ERCC1 INO80B INO80B ENSRROP00000041057 ENSRROP00000041057 ENSRROP00000040711 ENSRROP00000040711 LOC104662867 LOC104662867 RPA1 RPA1 ACTR5 ACTR5 RFC2 RFC2 WDR76 WDR76 ACTR8 ACTR8 ENSRROP00000038566 ENSRROP00000038566 RNF111 RNF111 YY1 YY1 ENSRROP00000037750 ENSRROP00000037750 COPS7A COPS7A DDB1 DDB1 COPS5 COPS5 CHD1L CHD1L COPS2 COPS2 ENSRROP00000035203 ENSRROP00000035203 POLD3 POLD3 ATAD5 ATAD5 ERCC3 ERCC3 CDK7 CDK7 ENSRROP00000034135 ENSRROP00000034135 TFPT TFPT ERCC2 ERCC2 CUL4A CUL4A ENSRROP00000033278 ENSRROP00000033278 RAD23A RAD23A RFC5 RFC5 LOC104673998 LOC104673998 LIG1 LIG1 NFRKB NFRKB GTF2H2 GTF2H2 POLD1 POLD1 GTF2H5 GTF2H5 UBE2N UBE2N XPC XPC POLK POLK COPS7B COPS7B LOC104680738 LOC104680738 POLD4 POLD4 RCBTB1 RCBTB1 RPS27A RPS27A RUVBL1 RUVBL1 LOC104673770 LOC104673770 RPA3 RPA3 XRCC1 XRCC1 COPS3 COPS3 ENSRROP00000026126 ENSRROP00000026126 LOC104678031 LOC104678031 ENSRROP00000025981 ENSRROP00000025981 PARP2 PARP2 CETN3 CETN3 POLE3 POLE3 NFATC2IP NFATC2IP PIAS3 PIAS3 COPS6 COPS6 MNAT1 MNAT1 USP45 USP45 RCBTB2 RCBTB2 INO80E INO80E SUMO1 SUMO1 ACTL6A ACTL6A CCNH CCNH ENSRROP00000021770 ENSRROP00000021770 COPS4 COPS4 COPS8 COPS8 VTCN1 VTCN1 VWA5A VWA5A UBA52 UBA52 PARP3 PARP3 SUMO2 SUMO2 UBC UBC INO80 INO80 ENSRROP00000018014 ENSRROP00000018014 BIVM BIVM WBP1 WBP1 ENSRROP00000014234 ENSRROP00000014234 ENSRROP00000013583 ENSRROP00000013583 INO80C INO80C RFC4 RFC4 GPS1 GPS1 CUL4B CUL4B POLE2 POLE2 XPA XPA PCNA PCNA GTF2H3 GTF2H3 PARP1 PARP1 PIAS1 PIAS1 CETN2 CETN2 RBX1 RBX1 RFC3 RFC3 ACTB ACTB POLE POLE MCRS1 MCRS1 ENSRROP00000007983 ENSRROP00000007983 RPAP3 RPAP3 ENSRROP00000007615 ENSRROP00000007615 UBE2NL UBE2NL LOC104665503 LOC104665503 ENSRROP00000005750 ENSRROP00000005750 MEIOB MEIOB ENSRROP00000005625 ENSRROP00000005625 LIG3 LIG3 ERCC4 ERCC4 ENSRROP00000005185 ENSRROP00000005185 UBE2V2 UBE2V2 LOC104668566 LOC104668566 ENSRROP00000003296 ENSRROP00000003296 LOC104657153 LOC104657153 RFC1 RFC1 ENSRROP00000002454 ENSRROP00000002454 LOC104659073 LOC104659073 LOC104679715 LOC104679715 LOC104657230 LOC104657230 SUMO2-2 SUMO2-2 INO80D INO80D POLE4 POLE4
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
VWA5B2Von Willebrand factor A domain containing 5B2. (1241 aa)
DDB2Damage specific DNA binding protein 2. (455 aa)
GTF2H4General transcription factor IIH subunit 4; Component of the general transcription and DNA repair factor IIH (TFIIH) core complex which is involved in general and transcription-coupled nucleotide excision repair (NER) of damaged DNA. Belongs to the TFB2 family. (462 aa)
ENSRROP00000044797Ubiquitin-like domain-containing protein. (136 aa)
VWA5B1Von Willebrand factor A domain containing 5B1. (1215 aa)
ENSRROP00000043101Ig-like domain-containing protein. (244 aa)
POLD2DNA polymerase delta 2, accessory subunit. (536 aa)
GTF2H1General transcription factor IIH subunit 1. (557 aa)
LOC104664457Uncharacterized protein. (72 aa)
KCTD2Potassium channel tetramerization domain containing 2. (263 aa)
UBE2IUbiquitin conjugating enzyme E2 I; Belongs to the ubiquitin-conjugating enzyme family. (231 aa)
RAD23BRAD23 homolog B, nucleotide excision repair protein. (409 aa)
ERCC1ERCC excision repair 1, endonuclease non-catalytic subunit. (322 aa)
INO80BPAPA-1 domain-containing protein. (373 aa)
ENSRROP00000041057Small ubiquitin-related modifier. (122 aa)
ENSRROP00000040711UBIQUITIN_CONJUGAT_2 domain-containing protein; Belongs to the ubiquitin-conjugating enzyme family. (105 aa)
LOC104662867UBIQUITIN_CONJUGAT_2 domain-containing protein; Belongs to the ubiquitin-conjugating enzyme family. (112 aa)
RPA1Replication protein A subunit; As part of the heterotrimeric replication protein A complex (RPA/RP-A), binds and stabilizes single-stranded DNA intermediates, that form during DNA replication or upon DNA stress. It prevents their reannealing and in parallel, recruits and activates different proteins and complexes involved in DNA metabolism. Thereby, it plays an essential role both in DNA replication and the cellular response to DNA damage. (580 aa)
ACTR5Actin related protein 5; Belongs to the actin family. (515 aa)
RFC2Replication factor C subunit 2. (332 aa)
WDR76WD repeat-containing protein 76; Specifically binds 5-hydroxymethylcytosine (5hmC), suggesting that it acts as a specific reader of 5hmC. Belongs to the WD repeat DDB2/WDR76 family. (626 aa)
ACTR8Actin-related protein 8; Plays an important role in the functional organization of mitotic chromosomes. Exhibits low basal ATPase activity, and unable to polymerize; Belongs to the actin family. ARP8 subfamily. (624 aa)
ENSRROP00000038566Rad60-SLD domain-containing protein. (81 aa)
RNF111Ring finger protein 111. (993 aa)
YY1Uncharacterized protein. (191 aa)
ENSRROP00000037750Ubiquitin-like domain-containing protein. (121 aa)
COPS7ACOP9 signalosome subunit 7A. (275 aa)
DDB1Damage specific DNA binding protein 1. (1147 aa)
COPS5COP9 signalosome subunit 5. (334 aa)
CHD1LChromodomain helicase DNA binding protein 1 like. (888 aa)
COPS2COP9 signalosome subunit 2. (403 aa)
ENSRROP00000035203Ubiquitin-like domain-containing protein. (141 aa)
POLD3Uncharacterized protein. (466 aa)
ATAD5ATPase family AAA domain containing 5. (1834 aa)
ERCC3ERCC excision repair 3, TFIIH core complex helicase subunit. (782 aa)
CDK7Cyclin dependent kinase 7; Belongs to the protein kinase superfamily. (346 aa)
ENSRROP00000034135Poly [ADP-ribose] polymerase. (856 aa)
TFPTTCF3 fusion partner. (263 aa)
ERCC2ERCC excision repair 2, TFIIH core complex helicase subunit. (760 aa)
CUL4ACullin 4A; Belongs to the cullin family. (659 aa)
ENSRROP00000033278Uncharacterized protein. (72 aa)
RAD23ARAD23 homolog A, nucleotide excision repair protein. (369 aa)
RFC5Replication factor C subunit 5. (340 aa)
LOC104673998UBIQUITIN_CONJUGAT_2 domain-containing protein; Belongs to the ubiquitin-conjugating enzyme family. (154 aa)
LIG1DNA ligase. (919 aa)
NFRKBNuclear factor related to kappaB binding protein. (1299 aa)
GTF2H2General transcription factor IIH subunit. (395 aa)
POLD1DNA polymerase. (1143 aa)
GTF2H5General transcription factor IIH subunit 5. (71 aa)
UBE2NUbiquitin conjugating enzyme E2 N; Belongs to the ubiquitin-conjugating enzyme family. (152 aa)
XPCXPC complex subunit, DNA damage recognition and repair factor. (939 aa)
POLKDNA polymerase kappa. (870 aa)
COPS7BCOP9 signalosome subunit 7B. (273 aa)
LOC104680738UBIQUITIN_CONJUGAT_2 domain-containing protein; Belongs to the ubiquitin-conjugating enzyme family. (152 aa)
POLD4Uncharacterized protein. (107 aa)
RCBTB1RCC1 and BTB domain containing protein 1. (531 aa)
RPS27AUbiquitin-like domain-containing protein. (156 aa)
RUVBL1RuvB-like helicase; Proposed core component of the chromatin remodeling Ino80 complex which exhibits DNA- and nucleosome-activated ATPase activity and catalyzes ATP-dependent nucleosome sliding. (456 aa)
LOC104673770Proliferating cell nuclear antigen; This protein is an auxiliary protein of DNA polymerase delta and is involved in the control of eukaryotic DNA replication by increasing the polymerase's processibility during elongation of the leading strand; Belongs to the PCNA family. (237 aa)
RPA3Uncharacterized protein. (121 aa)
XRCC1X-ray repair cross complementing 1. (633 aa)
COPS3COP9 signalosome subunit 3. (423 aa)
ENSRROP00000026126Ubiquitin-like domain-containing protein. (77 aa)
LOC104678031UBIQUITIN_CONJUGAT_2 domain-containing protein; Belongs to the ubiquitin-conjugating enzyme family. (152 aa)
ENSRROP00000025981UBIQUITIN_CONJUGAT_2 domain-containing protein; Belongs to the ubiquitin-conjugating enzyme family. (140 aa)
PARP2Poly [ADP-ribose] polymerase. (570 aa)
CETN3Centrin 3. (191 aa)
POLE3DNA polymerase epsilon 3, accessory subunit. (147 aa)
NFATC2IPNuclear factor of activated T cells 2 interacting protein. (419 aa)
PIAS3Protein inhibitor of activated STAT 3. (634 aa)
COPS6MPN domain-containing protein. (327 aa)
MNAT1CDK-activating kinase assembly factor MAT1; Stabilizes the cyclin H-CDK7 complex to form a functional CDK-activating kinase (CAK) enzymatic complex. (309 aa)
USP45Ubiquitin carboxyl-terminal hydrolase; Deubiquitinating enzyme that removes conjugated ubiquitin from specific proteins to regulate different cellular processes. Belongs to the peptidase C19 family. (815 aa)
RCBTB2RCC1 and BTB domain containing protein 2. (561 aa)
INO80EINO80 complex subunit E. (244 aa)
SUMO1Ubiquitin-like domain-containing protein. (145 aa)
ACTL6AActin like 6A; Belongs to the actin family. (429 aa)
CCNHCyclin H; Belongs to the cyclin family. (325 aa)
ENSRROP00000021770Ubiquitin-like domain-containing protein. (166 aa)
COPS4COP9 signalosome subunit 4. (437 aa)
COPS8COP9 signalosome subunit 8. (209 aa)
VTCN1V-set domain containing T cell activation inhibitor 1. (285 aa)
VWA5AVon Willebrand factor A domain containing 5A. (790 aa)
UBA52Ubiquitin A-52 residue ribosomal protein fusion product 1. (232 aa)
PARP3Poly [ADP-ribose] polymerase. (531 aa)
SUMO2Small ubiquitin-related modifier. (94 aa)
UBCUncharacterized protein. (351 aa)
INO80INO80 complex ATPase subunit. (1556 aa)
ENSRROP00000018014Protein kinase domain-containing protein. (315 aa)
BIVMBIVM-ERCC5 readthrough. (1640 aa)
WBP1WW domain binding protein 1. (302 aa)
ENSRROP00000014234Uncharacterized protein. (63 aa)
ENSRROP00000013583RFC1 domain-containing protein. (133 aa)
INO80CINO80 complex subunit C. (228 aa)
RFC4Replication factor C subunit 4. (363 aa)
GPS1G protein pathway suppressor 1. (527 aa)
CUL4BCullin 4B; Belongs to the cullin family. (913 aa)
POLE2DNA polymerase epsilon subunit; Participates in DNA repair and in chromosomal DNA replication; Belongs to the DNA polymerase epsilon subunit B family. (527 aa)
XPAXPA, DNA damage recognition and repair factor. (273 aa)
PCNAProliferating cell nuclear antigen; This protein is an auxiliary protein of DNA polymerase delta and is involved in the control of eukaryotic DNA replication by increasing the polymerase's processibility during elongation of the leading strand; Belongs to the PCNA family. (261 aa)
GTF2H3General transcription factor IIH subunit 3. (308 aa)
PARP1Poly [ADP-ribose] polymerase; Poly-ADP-ribosyltransferase that mediates poly-ADP- ribosylation of proteins and plays a key role in DNA repair. (1014 aa)
PIAS1Protein inhibitor of activated STAT 1. (653 aa)
CETN2Centrin 2. (172 aa)
RBX1Ring-box 1. (108 aa)
RFC3Replication factor C subunit 3. (356 aa)
ACTBActin beta. (375 aa)
POLEDNA polymerase epsilon catalytic subunit; DNA polymerase II participates in chromosomal DNA replication; Belongs to the DNA polymerase type-B family. (2288 aa)
MCRS1Microspherule protein 1. (475 aa)
ENSRROP00000007983Uncharacterized protein. (380 aa)
RPAP3RNA polymerase II associated protein 3. (664 aa)
ENSRROP00000007615Uncharacterized protein. (466 aa)
UBE2NLUBIQUITIN_CONJUGAT_2 domain-containing protein; Belongs to the ubiquitin-conjugating enzyme family. (89 aa)
LOC104665503UBIQUITIN_CONJUGAT_2 domain-containing protein; Belongs to the ubiquitin-conjugating enzyme family. (152 aa)
ENSRROP00000005750Ubiquitin-like domain-containing protein. (77 aa)
MEIOBMeiosis specific with OB-fold. (471 aa)
ENSRROP00000005625Ubiquitin-like domain-containing protein. (84 aa)
LIG3DNA ligase. (1009 aa)
ERCC4ERCC excision repair 4, endonuclease catalytic subunit. (916 aa)
ENSRROP00000005185Uncharacterized protein. (120 aa)
UBE2V2UBIQUITIN_CONJUGAT_2 domain-containing protein. (97 aa)
LOC104668566UBIQUITIN_CONJUGAT_2 domain-containing protein. (145 aa)
ENSRROP00000003296Ubiquitin-like domain-containing protein. (96 aa)
LOC104657153Ubiquitin-like domain-containing protein. (128 aa)
RFC1Replication factor C subunit 1. (1148 aa)
ENSRROP00000002454UBIQUITIN_CONJUGAT_2 domain-containing protein. (145 aa)
LOC104659073Ubiquitin-like domain-containing protein. (76 aa)
LOC104679715MPN domain-containing protein. (331 aa)
LOC104657230Ubiquitin-like domain-containing protein. (156 aa)
SUMO2-2Small ubiquitin-related modifier. (95 aa)
INO80DINO80 complex subunit D. (1027 aa)
POLE4DNA polymerase epsilon 4, accessory subunit. (129 aa)
Your Current Organism:
Rhinopithecus roxellana
NCBI taxonomy Id: 61622
Other names: Pygathrix roxellana, R. roxellana, golden snub-nosed monkey
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