STRINGSTRING
ENSRROP00000012792 ENSRROP00000012792 SNRPG SNRPG BCL2L2-PABPN1 BCL2L2-PABPN1 ALYREF ALYREF ENSRROP00000044639 ENSRROP00000044639 CSTF2 CSTF2 THOC1 THOC1 CPSF7 CPSF7 FIP1L1 FIP1L1 CPSF1 CPSF1 ENSRROP00000042968 ENSRROP00000042968 SRSF3 SRSF3 LOC104659628 LOC104659628 CSTF3 CSTF3 SRSF5 SRSF5 ZC3H11A ZC3H11A CPSF6 CPSF6 CSTF2T CSTF2T SRSF2 SRSF2 EIF4A3 EIF4A3 SRSF9 SRSF9 THOC2 THOC2 ENSRROP00000036150 ENSRROP00000036150 SRSF1 SRSF1 ZNF473 ZNF473 RNPS1 RNPS1 UPF3B UPF3B CPSF4 CPSF4 ENSRROP00000033668 ENSRROP00000033668 RBM8A RBM8A THOC6 THOC6 SRSF11 SRSF11 DDX39B DDX39B WDR25 WDR25 ENSRROP00000031168 ENSRROP00000031168 CLP1 CLP1 MAGOHB MAGOHB ZNF318 ZNF318 ENSRROP00000029240 ENSRROP00000029240 ENSRROP00000028004 ENSRROP00000028004 ENSRROP00000026765 ENSRROP00000026765 CPSF4L CPSF4L ENSRROP00000026122 ENSRROP00000026122 U2AF1 U2AF1 ENSRROP00000025753 ENSRROP00000025753 TPRG1 TPRG1 LOC104663968 LOC104663968 SNRPB SNRPB SARNP SARNP SRRM1 SRRM1 CPSF2 CPSF2 NUDT21 NUDT21 WDR33 WDR33 C12orf50 C12orf50 U2AF1L4 U2AF1L4 ENSRROP00000020651 ENSRROP00000020651 CPSF3 CPSF3 ENSRROP00000017880 ENSRROP00000017880 ENSRROP00000017857 ENSRROP00000017857 SNRPG-2 SNRPG-2 TPRG1L TPRG1L NCBP2 NCBP2 SNRPE SNRPE ENSRROP00000014292 ENSRROP00000014292 LUZP4 LUZP4 LOC104669438 LOC104669438 SNRPD3 SNRPD3 U2AF2 U2AF2 SNRPF SNRPF THOC3 THOC3 ENSRROP00000012907 ENSRROP00000012907 MAGOH MAGOH SLBP SLBP SRSF6 SRSF6 NCBP1 NCBP1 ENSRROP00000010290 ENSRROP00000010290 CDC40 CDC40 SRSF4 SRSF4 THOC5 THOC5 PCF11 PCF11 ENSRROP00000008784 ENSRROP00000008784 DHX38 DHX38 DDX39A DDX39A PAPOLA PAPOLA SYMPK SYMPK POLDIP3 POLDIP3 CASC3 CASC3 LOC104657389 LOC104657389 ZC3H13 ZC3H13 SREK1 SREK1 FYTTD1 FYTTD1 LSM11 LSM11 LSM10 LSM10 SLU7 SLU7 THOC7 THOC7 CSTF1 CSTF1 SRSF7 SRSF7 CHTOP CHTOP
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
ENSRROP00000012792Uncharacterized protein. (121 aa)
SNRPGSmall nuclear ribonucleoprotein G; Plays role in pre-mRNA splicing as core component of the SMN- Sm complex that mediates spliceosomal snRNP assembly and as component of the spliceosomal U1, U2, U4 and U5 small nuclear ribonucleoproteins (snRNPs), the building blocks of the spliceosome. Component of both the pre-catalytic spliceosome B complex and activated spliceosome C complexes. Is also a component of the minor U12 spliceosome. As part of the U7 snRNP it is involved in histone 3'-end processing. (76 aa)
BCL2L2-PABPN1BCL2L2-PABPN1 readthrough. (323 aa)
ALYREFAly/REF export factor. (279 aa)
ENSRROP00000044639Small nuclear ribonucleoprotein G; Plays role in pre-mRNA splicing as core component of the SMN- Sm complex that mediates spliceosomal snRNP assembly and as component of the spliceosomal U1, U2, U4 and U5 small nuclear ribonucleoproteins (snRNPs), the building blocks of the spliceosome. Component of both the pre-catalytic spliceosome B complex and activated spliceosome C complexes. Is also a component of the minor U12 spliceosome. As part of the U7 snRNP it is involved in histone 3'-end processing. (72 aa)
CSTF2Cleavage stimulation factor subunit 2. (597 aa)
THOC1THO complex 1. (657 aa)
CPSF7Cleavage and polyadenylation specific factor 7. (511 aa)
FIP1L1Fip1 domain-containing protein. (603 aa)
CPSF1Cleavage and polyadenylation specific factor 1. (1442 aa)
ENSRROP00000042968SAP domain-containing protein. (211 aa)
SRSF3Serine and arginine rich splicing factor 3. (164 aa)
LOC104659628Uncharacterized protein. (145 aa)
CSTF3Cleavage stimulation factor subunit 3. (717 aa)
SRSF5Serine and arginine rich splicing factor 5. (272 aa)
ZC3H11AUncharacterized protein. (810 aa)
CPSF6Cleavage and polyadenylation specific factor 6. (588 aa)
CSTF2TCleavage stimulation factor subunit 2 tau variant. (611 aa)
SRSF2Serine and arginine rich splicing factor 2. (221 aa)
EIF4A3Eukaryotic translation initiation factor 4A3; Belongs to the DEAD box helicase family. (411 aa)
SRSF9Serine and arginine rich splicing factor 9. (191 aa)
THOC2THO complex 2. (1595 aa)
ENSRROP00000036150PWI domain-containing protein. (408 aa)
SRSF1Uncharacterized protein. (253 aa)
ZNF473Zinc finger protein 473. (876 aa)
RNPS1RNA binding protein with serine rich domain 1. (305 aa)
UPF3BUPF3B regulator of nonsense mediated mRNA decay. (483 aa)
CPSF4Cleavage and polyadenylation specific factor 4. (248 aa)
ENSRROP00000033668RRM domain-containing protein. (297 aa)
RBM8ARNA-binding protein 8A; Core component of the splicing-dependent multiprotein exon junction complex (EJC) deposited at splice junctions on mRNAs. (174 aa)
THOC6THO complex 6. (341 aa)
SRSF11Serine and arginine rich splicing factor 11. (483 aa)
DDX39BDExD-box helicase 39B. (428 aa)
WDR25WD repeat domain 25. (544 aa)
ENSRROP00000031168SAP domain-containing protein. (179 aa)
CLP1Polyribonucleotide 5'-hydroxyl-kinase Clp1; Polynucleotide kinase that can phosphorylate the 5'-hydroxyl groups of double-stranded RNA (dsRNA), single-stranded RNA (ssRNA), double stranded DNA (dsDNA) and double-stranded DNA:RNA hybrids. dsRNA is phosphorylated more efficiently than dsDNA, and the RNA component of a DNA:RNA hybrid is phosphorylated more efficiently than the DNA component. Appears to have roles in both tRNA splicing and mRNA 3'-end formation. Component of the tRNA splicing endonuclease complex. Phosphorylates the 5'-terminus of the tRNA 3'-exon during tRNA splicing; thi [...] (436 aa)
MAGOHBMago homolog B, exon junction complex subunit. (148 aa)
ZNF318Zinc finger protein 318. (2099 aa)
ENSRROP00000029240Nuclear cap-binding protein subunit 2; Component of the cap-binding complex (CBC), which binds co- transcriptionally to the 5' cap of pre-mRNAs and is involved in various processes such as pre-mRNA splicing, translation regulation, nonsense- mediated mRNA decay, RNA-mediated gene silencing (RNAi) by microRNAs (miRNAs) and mRNA export. The CBC complex is involved in mRNA export from the nucleus, leading to the recruitment of the mRNA export machinery to the 5' end of mRNA and to mRNA export in a 5' to 3' direction through the nuclear pore. The CBC complex is also involved in mediating U [...] (103 aa)
ENSRROP00000028004RRM domain-containing protein. (298 aa)
ENSRROP00000026765Small nuclear ribonucleoprotein G; Plays role in pre-mRNA splicing as core component of the SMN- Sm complex that mediates spliceosomal snRNP assembly and as component of the spliceosomal U1, U2, U4 and U5 small nuclear ribonucleoproteins (snRNPs), the building blocks of the spliceosome. Component of both the pre-catalytic spliceosome B complex and activated spliceosome C complexes. Is also a component of the minor U12 spliceosome. As part of the U7 snRNP it is involved in histone 3'-end processing. (74 aa)
CPSF4LCleavage and polyadenylation specific factor 4 like. (179 aa)
ENSRROP00000026122Uncharacterized protein. (207 aa)
U2AF1Uncharacterized protein. (248 aa)
ENSRROP00000025753Sm domain-containing protein. (56 aa)
TPRG1Tumor protein p63 regulated 1. (279 aa)
LOC104663968RRM domain-containing protein. (287 aa)
SNRPBSmall nuclear ribonucleoprotein-associated protein. (240 aa)
SARNPSAP domain containing ribonucleoprotein. (210 aa)
SRRM1Serine and arginine repetitive matrix 1. (913 aa)
CPSF2Cleavage and polyadenylation specificity factor subunit 2. (782 aa)
NUDT21Cleavage and polyadenylation specificity factor subunit 5; Component of the cleavage factor Im (CFIm) complex that functions as an activator of the pre-mRNA 3'-end cleavage and polyadenylation processing required for the maturation of pre-mRNA into functional mRNAs. CFIm contributes to the recruitment of multiprotein complexes on specific sequences on the pre-mRNA 3'-end, so called cleavage and polyadenylation signals (pA signals). Most pre-mRNAs contain multiple pA signals, resulting in alternative cleavage and polyadenylation (APA) producing mRNAs with variable 3'-end formation. The [...] (227 aa)
WDR33WD repeat domain 33. (1336 aa)
C12orf50Chromosome 12 open reading frame 50. (413 aa)
U2AF1L4C3H1-type domain-containing protein. (208 aa)
ENSRROP00000020651Small nuclear ribonucleoprotein G; Plays role in pre-mRNA splicing as core component of the SMN- Sm complex that mediates spliceosomal snRNP assembly and as component of the spliceosomal U1, U2, U4 and U5 small nuclear ribonucleoproteins (snRNPs), the building blocks of the spliceosome. Component of both the pre-catalytic spliceosome B complex and activated spliceosome C complexes. Is also a component of the minor U12 spliceosome. As part of the U7 snRNP it is involved in histone 3'-end processing. (67 aa)
CPSF3Cleavage and polyadenylation specific factor 3. (684 aa)
ENSRROP00000017880RNA-binding protein 8A; Core component of the splicing-dependent multiprotein exon junction complex (EJC) deposited at splice junctions on mRNAs. (169 aa)
ENSRROP00000017857Uncharacterized protein. (67 aa)
SNRPG-2Small nuclear ribonucleoprotein G; Plays role in pre-mRNA splicing as core component of the SMN- Sm complex that mediates spliceosomal snRNP assembly and as component of the spliceosomal U1, U2, U4 and U5 small nuclear ribonucleoproteins (snRNPs), the building blocks of the spliceosome. Component of both the pre-catalytic spliceosome B complex and activated spliceosome C complexes. Is also a component of the minor U12 spliceosome. As part of the U7 snRNP it is involved in histone 3'-end processing. (74 aa)
TPRG1LHSac2 domain-containing protein. (77 aa)
NCBP2Nuclear cap-binding protein subunit 2; Component of the cap-binding complex (CBC), which binds co- transcriptionally to the 5' cap of pre-mRNAs and is involved in various processes such as pre-mRNA splicing, translation regulation, nonsense- mediated mRNA decay, RNA-mediated gene silencing (RNAi) by microRNAs (miRNAs) and mRNA export. The CBC complex is involved in mRNA export from the nucleus, leading to the recruitment of the mRNA export machinery to the 5' end of mRNA and to mRNA export in a 5' to 3' direction through the nuclear pore. The CBC complex is also involved in mediating U [...] (166 aa)
SNRPESmall nuclear ribonucleoprotein E; Plays role in pre-mRNA splicing as core component of the SMN- Sm complex that mediates spliceosomal snRNP assembly and as component of the spliceosomal U1, U2, U4 and U5 small nuclear ribonucleoproteins (snRNPs), the building blocks of the spliceosome. Component of both the pre-catalytic spliceosome B complex and activated spliceosome C complexes. Is also a component of the minor U12 spliceosome. As part of the U7 snRNP it is involved in histone 3'-end processing. May indirectly play a role in hair development. (92 aa)
ENSRROP00000014292Small nuclear ribonucleoprotein E; Plays role in pre-mRNA splicing as core component of the SMN- Sm complex that mediates spliceosomal snRNP assembly and as component of the spliceosomal U1, U2, U4 and U5 small nuclear ribonucleoproteins (snRNPs), the building blocks of the spliceosome. Component of both the pre-catalytic spliceosome B complex and activated spliceosome C complexes. Is also a component of the minor U12 spliceosome. As part of the U7 snRNP it is involved in histone 3'-end processing. May indirectly play a role in hair development. (85 aa)
LUZP4Leucine zipper protein 4. (306 aa)
LOC104669438U2 snRNP auxiliary factor large subunit; Necessary for the splicing of pre-mRNA. Belongs to the splicing factor SR family. (461 aa)
SNRPD3Small nuclear ribonucleoprotein Sm D3; Plays role in pre-mRNA splicing as core component of the SMN- Sm complex that mediates spliceosomal snRNP assembly and as component of the spliceosomal U1, U2, U4 and U5 small nuclear ribonucleoproteins (snRNPs), the building blocks of the spliceosome. Component of both the pre-catalytic spliceosome B complex and activated spliceosome C complexes. Is also a component of the minor U12 spliceosome. As part of the U7 snRNP it is involved in histone pre-mRNA 3'-end processing. (126 aa)
U2AF2U2 snRNP auxiliary factor large subunit; Necessary for the splicing of pre-mRNA. Belongs to the splicing factor SR family. (414 aa)
SNRPFSm domain-containing protein. (127 aa)
THOC3THO complex 3. (351 aa)
ENSRROP00000012907Uncharacterized protein. (116 aa)
MAGOHMago homolog, exon junction complex subunit. (283 aa)
SLBPStem-loop binding protein. (274 aa)
SRSF6Serine and arginine rich splicing factor 6. (343 aa)
NCBP1Nuclear cap binding protein subunit 1. (790 aa)
ENSRROP00000010290Small nuclear ribonucleoprotein G; Plays role in pre-mRNA splicing as core component of the SMN- Sm complex that mediates spliceosomal snRNP assembly and as component of the spliceosomal U1, U2, U4 and U5 small nuclear ribonucleoproteins (snRNPs), the building blocks of the spliceosome. Component of both the pre-catalytic spliceosome B complex and activated spliceosome C complexes. Is also a component of the minor U12 spliceosome. As part of the U7 snRNP it is involved in histone 3'-end processing. (66 aa)
CDC40Cell division cycle 40. (579 aa)
SRSF4Serine and arginine rich splicing factor 4. (494 aa)
THOC5THO complex 5. (694 aa)
PCF11PCF11 cleavage and polyadenylation factor subunit. (1718 aa)
ENSRROP00000008784C3H1-type domain-containing protein. (247 aa)
DHX38DEAH-box helicase 38. (1227 aa)
DDX39ADExD-box helicase 39A. (488 aa)
PAPOLAPoly(A) polymerase; Polymerase that creates the 3'-poly(A) tail of mRNA's. (745 aa)
SYMPKSymplekin. (1290 aa)
POLDIP3DNA polymerase delta interacting protein 3. (421 aa)
CASC3CASC3 exon junction complex subunit. (704 aa)
LOC104657389Sm domain-containing protein. (86 aa)
ZC3H13Zinc finger CCCH-type containing 13. (1555 aa)
SREK1Splicing regulatory glutamic acid and lysine rich protein 1. (626 aa)
FYTTD1Forty-two-three domain containing 1. (318 aa)
LSM11LSM11, U7 small nuclear RNA associated. (295 aa)
LSM10LSM10, U7 small nuclear RNA associated. (123 aa)
SLU7SLU7 homolog, splicing factor. (586 aa)
THOC7THO complex 7. (204 aa)
CSTF1Cleavage stimulation factor subunit 1. (431 aa)
SRSF7Serine and arginine rich splicing factor 7. (238 aa)
CHTOPChromatin target of PRMT1. (276 aa)
Your Current Organism:
Rhinopithecus roxellana
NCBI taxonomy Id: 61622
Other names: Pygathrix roxellana, R. roxellana, golden snub-nosed monkey
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