STRINGSTRING
RBL1 RBL1 ENSRROP00000000058 ENSRROP00000000058 ITGB8 ITGB8 ZCCHC4 ZCCHC4 FKBP1A FKBP1A LOC104657230 LOC104657230 TGFB3 TGFB3 TGIF2 TGIF2 ITGAV ITGAV ENSRROP00000001728 ENSRROP00000001728 LOC104659073 LOC104659073 LOC104659307 LOC104659307 LOC104657153 LOC104657153 ENSRROP00000003296 ENSRROP00000003296 TGFBR2 TGFBR2 FSTL1 FSTL1 PARD3B PARD3B GREM2 GREM2 ENSRROP00000003686 ENSRROP00000003686 SMURF2 SMURF2 GDF2 GDF2 ACVR2A ACVR2A NOG NOG PARD6A PARD6A UBE2M UBE2M MTMR4 MTMR4 ATP1B4 ATP1B4 ENSRROP00000005625 ENSRROP00000005625 ENSRROP00000005750 ENSRROP00000005750 SMAD3 SMAD3 ACVR1 ACVR1 JUNB JUNB WWTR1 WWTR1 IRX1 IRX1 TRIM33 TRIM33 CGN CGN IRX6 IRX6 AMH AMH MEIS3 MEIS3 SERPINE1 SERPINE1 PARP1 PARP1 LTBP4 LTBP4 ENSRROP00000009768 ENSRROP00000009768 CHRDL2 CHRDL2 IRX2 IRX2 SP1 SP1 BMPR2 BMPR2 PARD3 PARD3 BMP2 BMP2 ENSRROP00000011675 ENSRROP00000011675 CCNK CCNK MKX MKX ENSRROP00000012257 ENSRROP00000012257 ACVR1C ACVR1C TFDP1 TFDP1 INHBB INHBB SKI SKI RHOA RHOA ENSRROP00000015444 ENSRROP00000015444 HDAC1 HDAC1 MYC MYC YBX1 YBX1 DRAP1 DRAP1 ACVRL1 ACVRL1 STRAP STRAP CCNC CCNC PMEPA1 PMEPA1 UBC UBC IRX3 IRX3 SMURF1 SMURF1 ENSRROP00000019405 ENSRROP00000019405 E2F5 E2F5 TFDP2 TFDP2 UBA52 UBA52 FSTL3 FSTL3 ACVR1B ACVR1B SNW1 SNW1 BMPR1B BMPR1B LOC104661203 LOC104661203 ITGB5 ITGB5 INHBA INHBA ENSRROP00000021770 ENSRROP00000021770 LOC104666830 LOC104666830 AMHR2 AMHR2 USP9Y USP9Y ZFYVE9 ZFYVE9 PCSK4 PCSK4 ITGB3 ITGB3 SMAD2 SMAD2 E2F4 E2F4 BMPR1A BMPR1A NEDD8 NEDD8 TGIF1 TGIF1 TGFBR1 TGFBR1 LTBP2 LTBP2 MAPK1 MAPK1 FURIN FURIN MEN1 MEN1 MEIS1 MEIS1 SMAD5 SMAD5 ENSRROP00000026126 ENSRROP00000026126 ENSRROP00000026527 ENSRROP00000026527 ACVR2B ACVR2B ENSRROP00000027060 ENSRROP00000027060 PPP1CB PPP1CB USP15 USP15 RPS27A RPS27A FBN1 FBN1 CDKN2B CDKN2B EP300 EP300 STUB1 STUB1 LOC104677352 LOC104677352 CCNQ CCNQ XPO1 XPO1 IRX4 IRX4 IRX5 IRX5 CCNT2 CCNT2 FOXH1 FOXH1 CBL CBL UBE2D1 UBE2D1 NCOR1 NCOR1 MAPK3 MAPK3 BMP10 BMP10 PPP1CA PPP1CA TGFB2 TGFB2 STAT1 STAT1 ENSRROP00000034135 ENSRROP00000034135 CDK9 CDK9 USP9X USP9X ENSRROP00000035203 ENSRROP00000035203 ARHGEF18 ARHGEF18 ENSRROP00000036234 ENSRROP00000036234 ENSRROP00000036403 ENSRROP00000036403 CDK8 CDK8 TGIF2LX TGIF2LX LTBP1 LTBP1 LDLRAD4 LDLRAD4 ENSRROP00000037750 ENSRROP00000037750 SMAD1 SMAD1 RNF111 RNF111 PPM1A PPM1A NCOR2 NCOR2 PRKCZ PRKCZ CER1 CER1 ENSRROP00000039666 ENSRROP00000039666 SMAD6 SMAD6 TGFB1 TGFB1 LTBP3 LTBP3 F11R F11R SMAD7 SMAD7 PPP1CC PPP1CC SMAD9 SMAD9 COL1A2 COL1A2 CCNT1 CCNT1 SKIL SKIL ITGA8 ITGA8 ITGB6 ITGB6 SMAD4 SMAD4 ITGB1 ITGB1 CHRDL1 CHRDL1 FST FST BAMBI BAMBI LOC104673417 LOC104673417 ZFYVE16 ZFYVE16 NEDD4L NEDD4L
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
RBL1RB transcriptional corepressor like 1. (1033 aa)
ENSRROP00000000058Uncharacterized protein. (224 aa)
ITGB8Integrin beta; Belongs to the integrin beta chain family. (769 aa)
ZCCHC4Zinc finger CCHC-type containing 4. (513 aa)
FKBP1APeptidylprolyl isomerase. (127 aa)
LOC104657230Ubiquitin-like domain-containing protein. (156 aa)
TGFB3Transforming growth factor beta; Belongs to the TGF-beta family. (412 aa)
TGIF2TGFB induced factor homeobox 2. (237 aa)
ITGAVIntegrin subunit alpha V; Belongs to the integrin alpha chain family. (1048 aa)
ENSRROP00000001728CSD_1 domain-containing protein. (316 aa)
LOC104659073Ubiquitin-like domain-containing protein. (76 aa)
LOC104659307TB domain-containing protein. (166 aa)
LOC104657153Ubiquitin-like domain-containing protein. (128 aa)
ENSRROP00000003296Ubiquitin-like domain-containing protein. (96 aa)
TGFBR2TGF-beta receptor type-2; Transmembrane serine/threonine kinase forming with the TGF- beta type I serine/threonine kinase receptor, TGFBR1, the non- promiscuous receptor for the TGF-beta cytokines TGFB1, TGFB2 and TGFB3. Transduces the TGFB1, TGFB2 and TGFB3 signal from the cell surface to the cytoplasm and is thus regulating a plethora of physiological and pathological processes including cell cycle arrest in epithelial and hematopoietic cells, control of mesenchymal cell proliferation and differentiation, wound healing, extracellular matrix production, immunosuppression and carcinoge [...] (592 aa)
FSTL1Follistatin like 1. (318 aa)
PARD3BPar-3 family cell polarity regulator beta. (1204 aa)
GREM2Gremlin. (168 aa)
ENSRROP00000003686Ubiquitin-like domain-containing protein. (81 aa)
SMURF2E3 ubiquitin-protein ligase. (741 aa)
GDF2Growth differentiation factor 2. (429 aa)
ACVR2ASerine/threonine-protein kinase receptor; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily. (513 aa)
NOGNoggin; Inhibitor of bone morphogenetic proteins (BMP) signaling which is required for growth and patterning of the neural tube and somite. (232 aa)
PARD6APar-6 family cell polarity regulator alpha. (344 aa)
UBE2MUbiquitin conjugating enzyme E2 M; Belongs to the ubiquitin-conjugating enzyme family. (183 aa)
MTMR4Myotubularin related protein 4. (1195 aa)
ATP1B4Sodium/potassium-transporting ATPase subunit beta; This is the non-catalytic component of the active enzyme, which catalyzes the hydrolysis of ATP coupled with the exchange of Na(+) and K(+) ions across the plasma membrane. Belongs to the X(+)/potassium ATPases subunit beta family. (357 aa)
ENSRROP00000005625Ubiquitin-like domain-containing protein. (84 aa)
ENSRROP00000005750Ubiquitin-like domain-containing protein. (77 aa)
SMAD3Mothers against decapentaplegic homolog. (480 aa)
ACVR1Serine/threonine-protein kinase receptor; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily. (509 aa)
JUNBJunB proto-oncogene, AP-1 transcription factor subunit. (347 aa)
WWTR1WW domain containing transcription regulator 1. (400 aa)
IRX1Iroquois homeobox 1. (480 aa)
TRIM33Tripartite motif containing 33. (1270 aa)
CGNMyosin_tail_1 domain-containing protein. (1210 aa)
IRX6Iroquois homeobox 6. (444 aa)
AMHAnti-Mullerian hormone. (516 aa)
MEIS3Meis homeobox 3. (446 aa)
SERPINE1Serpin family E member 1; Belongs to the serpin family. (444 aa)
PARP1Poly [ADP-ribose] polymerase; Poly-ADP-ribosyltransferase that mediates poly-ADP- ribosylation of proteins and plays a key role in DNA repair. (1014 aa)
LTBP4Latent transforming growth factor beta binding protein 4. (1583 aa)
ENSRROP00000009768Uncharacterized protein. (260 aa)
CHRDL2Chordin like 2. (430 aa)
IRX2Iroquois homeobox 2. (453 aa)
SP1Sp1 transcription factor. (786 aa)
BMPR2Receptor protein serine/threonine kinase; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily. (1002 aa)
PARD3Par-3 family cell polarity regulator. (1325 aa)
BMP2Bone morphogenetic protein 2. (470 aa)
ENSRROP00000011675Uncharacterized protein. (270 aa)
CCNKCyclin K; Belongs to the cyclin family. (493 aa)
MKXMohawk homeobox. (352 aa)
ENSRROP00000012257Uncharacterized protein. (92 aa)
ACVR1CReceptor protein serine/threonine kinase; Belongs to the protein kinase superfamily. (396 aa)
TFDP1Transcription factor. (410 aa)
INHBBInhibin subunit beta B. (396 aa)
SKISKI proto-oncogene. (770 aa)
RHOARas homolog family member A. (193 aa)
ENSRROP00000015444Peptidylprolyl isomerase. (107 aa)
HDAC1Histone deacetylase 1; Responsible for the deacetylation of lysine residues on the N-terminal part of the core histones (H2A, H2B, H3 and H4). Histone deacetylation gives a tag for epigenetic repression and plays an important role in transcriptional regulation, cell cycle progression and developmental events. Histone deacetylases act via the formation of large multiprotein complexes. (477 aa)
MYCMyc proto-oncogene protein; Transcription factor that binds DNA in a non-specific manner, yet also specifically recognizes the core sequence 5'-CAC[GA]TG-3'. Activates the transcription of growth-related genes. (439 aa)
YBX1CSD_1 domain-containing protein. (324 aa)
DRAP1DR1 associated protein 1. (250 aa)
ACVRL1Serine/threonine-protein kinase receptor; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily. (503 aa)
STRAPSerine/threonine kinase receptor associated protein. (363 aa)
CCNCCyclin C; Belongs to the cyclin family. (283 aa)
PMEPA1Prostate transmembrane protein, androgen induced 1. (257 aa)
UBCUncharacterized protein. (351 aa)
IRX3Iroquois homeobox 3. (501 aa)
SMURF1E3 ubiquitin-protein ligase. (764 aa)
ENSRROP00000019405Hist_deacetyl domain-containing protein. (352 aa)
E2F5E2F transcription factor 5. (345 aa)
TFDP2Transcription factor. (447 aa)
UBA52Ubiquitin A-52 residue ribosomal protein fusion product 1. (232 aa)
FSTL3Follistatin like 3. (282 aa)
ACVR1BReceptor protein serine/threonine kinase; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily. (506 aa)
SNW1SNW domain containing 1. (536 aa)
BMPR1BSerine/threonine-protein kinase receptor; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily. (532 aa)
LOC104661203CSD_1 domain-containing protein. (278 aa)
ITGB5Integrin beta; Belongs to the integrin beta chain family. (799 aa)
INHBAInhibin subunit beta A. (492 aa)
ENSRROP00000021770Ubiquitin-like domain-containing protein. (166 aa)
LOC104666830Uncharacterized protein. (286 aa)
AMHR2Anti-Muellerian hormone type-2 receptor; On ligand binding, forms a receptor complex consisting of two type II and two type I transmembrane serine/threonine kinases. Type II receptors phosphorylate and activate type I receptors which autophosphorylate, then bind and activate SMAD transcriptional regulators. Receptor for anti-Muellerian hormone. (573 aa)
USP9YUbiquitin specific peptidase 9 Y-linked; Belongs to the peptidase C19 family. (2551 aa)
ZFYVE9Zinc finger FYVE domain-containing protein. (1425 aa)
PCSK4Proprotein convertase subtilisin/kexin type 4; Belongs to the peptidase S8 family. (754 aa)
ITGB3Integrin beta; Belongs to the integrin beta chain family. (788 aa)
SMAD2Mothers against decapentaplegic homolog. (392 aa)
E2F4E2F transcription factor 4. (431 aa)
BMPR1AReceptor protein serine/threonine kinase; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily. (532 aa)
NEDD8Ubiquitin-like domain-containing protein. (82 aa)
TGIF1TGFB induced factor homeobox 1. (335 aa)
TGFBR1Receptor protein serine/threonine kinase; Belongs to the protein kinase superfamily. (498 aa)
LTBP2Latent transforming growth factor beta binding protein 2. (1821 aa)
MAPK1Mitogen-activated protein kinase. (330 aa)
FURINFurin, paired basic amino acid cleaving enzyme; Belongs to the peptidase S8 family. (830 aa)
MEN1Menin 1. (610 aa)
MEIS1Meis homeobox 1. (436 aa)
SMAD5Mothers against decapentaplegic homolog. (465 aa)
ENSRROP00000026126Ubiquitin-like domain-containing protein. (77 aa)
ENSRROP00000026527CYCLIN domain-containing protein; Belongs to the cyclin family. (264 aa)
ACVR2BSerine/threonine-protein kinase receptor; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily. (525 aa)
ENSRROP00000027060Uncharacterized protein. (600 aa)
PPP1CBSerine/threonine-protein phosphatase; Belongs to the PPP phosphatase family. (373 aa)
USP15Ubiquitin carboxyl-terminal hydrolase; Deubiquitinating enzyme that removes conjugated ubiquitin from specific proteins to regulate different cellular processes. Belongs to the peptidase C19 family. (981 aa)
RPS27AUbiquitin-like domain-containing protein. (156 aa)
FBN1Fibrillin 1. (2871 aa)
CDKN2BCyclin dependent kinase inhibitor 2B. (138 aa)
EP300E1A binding protein p300. (2413 aa)
STUB1STIP1 homology and U-box containing protein 1. (303 aa)
LOC104677352Histone deacetylase 1; Responsible for the deacetylation of lysine residues on the N-terminal part of the core histones (H2A, H2B, H3 and H4). Histone deacetylation gives a tag for epigenetic repression and plays an important role in transcriptional regulation, cell cycle progression and developmental events. Histone deacetylases act via the formation of large multiprotein complexes. (484 aa)
CCNQCyclin Q; Belongs to the cyclin family. (248 aa)
XPO1Exportin 1. (1071 aa)
IRX4Iroquois homeobox 4. (515 aa)
IRX5Iroquois homeobox 5. (483 aa)
CCNT2Cyclin T2; Belongs to the cyclin family. (730 aa)
FOXH1Forkhead box H1. (366 aa)
CBLCbl proto-oncogene. (906 aa)
UBE2D1Ubiquitin conjugating enzyme E2 D1; Belongs to the ubiquitin-conjugating enzyme family. (148 aa)
NCOR1Nuclear receptor corepressor 1. (2440 aa)
MAPK3Mitogen-activated protein kinase; Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. MAP kinase subfamily. (379 aa)
BMP10Bone morphogenetic protein 10. (424 aa)
PPP1CASerine/threonine-protein phosphatase; Belongs to the PPP phosphatase family. (367 aa)
TGFB2Transforming growth factor beta; Belongs to the TGF-beta family. (442 aa)
STAT1Signal transducer and activator of transcription. (787 aa)
ENSRROP00000034135Poly [ADP-ribose] polymerase. (856 aa)
CDK9Cyclin dependent kinase 9; Belongs to the protein kinase superfamily. (372 aa)
USP9XUncharacterized protein. (278 aa)
ENSRROP00000035203Ubiquitin-like domain-containing protein. (141 aa)
ARHGEF18Uncharacterized protein. (1173 aa)
ENSRROP00000036234Peptidylprolyl isomerase. (117 aa)
ENSRROP00000036403PPM-type phosphatase domain-containing protein. (342 aa)
CDK8Cyclin dependent kinase 8; Belongs to the protein kinase superfamily. (464 aa)
TGIF2LXTGFB induced factor homeobox 2 like X-linked. (242 aa)
LTBP1Latent transforming growth factor beta binding protein 1. (1691 aa)
LDLRAD4Low density lipoprotein receptor class A domain containing 4. (306 aa)
ENSRROP00000037750Ubiquitin-like domain-containing protein. (121 aa)
SMAD1Mothers against decapentaplegic homolog. (465 aa)
RNF111Ring finger protein 111. (993 aa)
PPM1AProtein phosphatase, Mg2+/Mn2+ dependent 1A. (455 aa)
NCOR2Nuclear receptor corepressor 2. (2522 aa)
PRKCZProtein kinase C; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. PKC subfamily. (582 aa)
CER1Cerberus 1, DAN family BMP antagonist. (267 aa)
ENSRROP00000039666Receptor protein serine/threonine kinase; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily. (483 aa)
SMAD6MH2 domain-containing protein. (226 aa)
TGFB1Transforming growth factor beta; Belongs to the TGF-beta family. (391 aa)
LTBP3Latent transforming growth factor beta binding protein 3. (1069 aa)
F11RF11 receptor. (299 aa)
SMAD7MH2 domain-containing protein. (211 aa)
PPP1CCSerine/threonine-protein phosphatase; Belongs to the PPP phosphatase family. (337 aa)
SMAD9Mothers against decapentaplegic homolog. (467 aa)
COL1A2Collagen type I alpha 2 chain. (1366 aa)
CCNT1Cyclin T1; Belongs to the cyclin family. (728 aa)
SKILSKI like proto-oncogene. (684 aa)
ITGA8Integrin subunit alpha 8; Belongs to the integrin alpha chain family. (1063 aa)
ITGB6Integrin beta; Belongs to the integrin beta chain family. (788 aa)
SMAD4Mothers against decapentaplegic homolog. (552 aa)
ITGB1Integrin beta; Belongs to the integrin beta chain family. (801 aa)
CHRDL1Chordin like 1. (457 aa)
FSTFollistatin. (350 aa)
BAMBIBMP and activin membrane-bound inhibitor homolog; Negatively regulates TGF-beta signaling. Belongs to the BAMBI family. (260 aa)
LOC104673417Homeobox domain-containing protein. (272 aa)
ZFYVE16Zinc finger FYVE domain-containing protein. (1537 aa)
NEDD4LNEDD4 like E3 ubiquitin protein ligase. (1255 aa)
Your Current Organism:
Rhinopithecus roxellana
NCBI taxonomy Id: 61622
Other names: Pygathrix roxellana, R. roxellana, golden snub-nosed monkey
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