STRINGSTRING
HRAS HRAS ENSRROP00000045475 ENSRROP00000045475 GNG8 GNG8 ZDHHC7 ZDHHC7 LOC104678360 LOC104678360 STRN3 STRN3 MMP7 MMP7 LOC104677425 LOC104677425 GNG12 GNG12 GNB2 GNB2 AKT2 AKT2 AREG AREG MMP3 MMP3 CSDE1 CSDE1 PRKCZ PRKCZ GNG11 GNG11 S1PR3 S1PR3 LOC104655302 LOC104655302 AKT1 AKT1 GNGT1 GNGT1 PDPK1 PDPK1 GNG2 GNG2 GNGT2 GNGT2 GNB3 GNB3 PIK3R2 PIK3R2 ENSRROP00000007762 ENSRROP00000007762 FOXO3 FOXO3 ZDHHC21 ZDHHC21 GNG7 GNG7 ENSRROP00000009442 ENSRROP00000009442 GNAI2 GNAI2 GNG13 GNG13 HBEGF HBEGF PIK3CA PIK3CA LOC104682584 LOC104682584 PRMT8 PRMT8 UHMK1 UHMK1 SPHK1 SPHK1 GNB1 GNB1 ENSRROP00000015769 ENSRROP00000015769 SHC1 SHC1 WDR64 WDR64 EPGN EPGN MMP9 MMP9 CCND1 CCND1 GNAI3 GNAI3 NRAS NRAS GNAT3 GNAT3 IGF1R IGF1R GNAI1 GNAI1 SRC SRC SRF SRF ENSRROP00000021080 ENSRROP00000021080 NOS3 NOS3 BTC BTC ENSRROP00000021314 ENSRROP00000021314 AKT3 AKT3 PIK3R1 PIK3R1 CAV2 CAV2 ENSRROP00000022234 ENSRROP00000022234 CREB1 CREB1 ENSRROP00000023133 ENSRROP00000023133 EGF EGF LOC104675682 LOC104675682 ENSRROP00000024190 ENSRROP00000024190 CAV1 CAV1 EREG EREG TGFA TGFA STRN4 STRN4 EGFR EGFR MAPK1 MAPK1 CDKN1B CDKN1B GNG3 GNG3 ENSRROP00000027148 ENSRROP00000027148 ERAS ERAS FOS FOS MMP2 MMP2 XPO1 XPO1 PIK3R3 PIK3R3 GNB5 GNB5 PRMT1 PRMT1 MAPK3 MAPK3 HSPB1 HSPB1 ESR2 ESR2 GNG4 GNG4 PTK2 PTK2 KRAS KRAS LOC104665116 LOC104665116 GNB4 GNB4 ENSRROP00000035890 ENSRROP00000035890 STRN STRN ENSRROP00000034142 ENSRROP00000034142 HSP90AA1 HSP90AA1 ELK1 ELK1 BCL2 BCL2 GNG5 GNG5
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
HRASHRas proto-oncogene, GTPase. (189 aa)
ENSRROP00000045475G protein gamma domain-containing protein. (58 aa)
GNG8Guanine nucleotide-binding protein subunit gamma; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction. (73 aa)
ZDHHC7Palmitoyltransferase; Belongs to the DHHC palmitoyltransferase family. (344 aa)
LOC104678360Nuclear receptor domain-containing protein. (231 aa)
STRN3Striatin 3. (797 aa)
MMP7Matrix metallopeptidase 7. (270 aa)
LOC104677425Uncharacterized protein. (157 aa)
GNG12Guanine nucleotide-binding protein subunit gamma; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction. (72 aa)
GNB2G protein subunit beta 2. (340 aa)
AKT2Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily. (481 aa)
AREGAmphiregulin. (274 aa)
MMP3Matrix metallopeptidase 3. (477 aa)
CSDE1Cold shock domain containing E1. (844 aa)
PRKCZProtein kinase C; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. PKC subfamily. (582 aa)
GNG11Guanine nucleotide-binding protein subunit gamma; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction. (74 aa)
S1PR3Sphingosine-1-phosphate receptor 3; Belongs to the G-protein coupled receptor 1 family. (378 aa)
LOC104655302SHSP domain-containing protein; Belongs to the small heat shock protein (HSP20) family. (205 aa)
AKT1Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily. (480 aa)
GNGT1Guanine nucleotide-binding protein subunit gamma; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction. (89 aa)
PDPK13-phosphoinositide dependent protein kinase 1. (356 aa)
GNG2Guanine nucleotide-binding protein subunit gamma; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction. (110 aa)
GNGT2Guanine nucleotide-binding protein subunit gamma; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction. (101 aa)
GNB3G protein subunit beta 3. (340 aa)
PIK3R2Uncharacterized protein. (647 aa)
ENSRROP00000007762Guanine nucleotide-binding protein subunit gamma; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction. (69 aa)
FOXO3Forkhead box O3. (617 aa)
ZDHHC21Palmitoyltransferase; Belongs to the DHHC palmitoyltransferase family. (265 aa)
GNG7Guanine nucleotide-binding protein subunit gamma; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction. (68 aa)
ENSRROP00000009442Uncharacterized protein. (179 aa)
GNAI2G protein subunit alpha i2. (355 aa)
GNG13G protein subunit gamma 13. (67 aa)
HBEGFHeparin binding EGF like growth factor. (208 aa)
PIK3CAPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit. (1068 aa)
LOC104682584HATPase_c domain-containing protein. (674 aa)
PRMT8Protein arginine methyltransferase 8; Belongs to the class I-like SAM-binding methyltransferase superfamily. Protein arginine N-methyltransferase family. (394 aa)
UHMK1U2AF homology motif kinase 1. (419 aa)
SPHK1Sphingosine kinase 1. (472 aa)
GNB1G protein subunit beta 1. (340 aa)
ENSRROP00000015769Uncharacterized protein. (279 aa)
SHC1SHC adaptor protein 1. (574 aa)
WDR64WD repeat domain 64. (1081 aa)
EPGNEpithelial mitogen. (154 aa)
MMP9Matrix metallopeptidase 9. (703 aa)
CCND1Cyclin D1; Belongs to the cyclin family. (253 aa)
GNAI3G protein subunit alpha i3. (354 aa)
NRASNRAS proto-oncogene, GTPase. (189 aa)
GNAT3Uncharacterized protein. (196 aa)
IGF1RTyrosine-protein kinase receptor. (1367 aa)
GNAI1G protein subunit alpha i1. (253 aa)
SRCTyrosine-protein kinase. (540 aa)
SRFSerum response factor. (508 aa)
ENSRROP00000021080Palmitoyltransferase; Belongs to the DHHC palmitoyltransferase family. (307 aa)
NOS3Nitric oxide synthase; Produces nitric oxide (NO). (1205 aa)
BTCBetacellulin. (178 aa)
ENSRROP00000021314ETS domain-containing protein. (421 aa)
AKT3Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily. (479 aa)
PIK3R1Phosphoinositide-3-kinase regulatory subunit 1. (724 aa)
CAV2Caveolin; May act as a scaffolding protein within caveolar membranes. Interacts directly with G-protein alpha subunits and can functionally regulate their activity; Belongs to the caveolin family. (162 aa)
ENSRROP00000022234Guanine nucleotide-binding protein subunit gamma; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction. (59 aa)
CREB1cAMP responsive element binding protein 1. (341 aa)
ENSRROP00000023133Uncharacterized protein. (235 aa)
EGFPro-epidermal growth factor; EGF stimulates the growth of various epidermal and epithelial tissues in vivo and in vitro and of some fibroblasts in cell culture. Magnesiotropic hormone that stimulates magnesium reabsorption in the renal distal convoluted tubule via engagement of EGFR and activation of the magnesium channel TRPM6. (1233 aa)
LOC104675682HATPase_c domain-containing protein. (671 aa)
ENSRROP00000024190Protein kinase domain-containing protein. (137 aa)
CAV1Caveolin; May act as a scaffolding protein within caveolar membranes. Interacts directly with G-protein alpha subunits and can functionally regulate their activity; Belongs to the caveolin family. (147 aa)
EREGEpiregulin. (163 aa)
TGFATransforming growth factor alpha. (166 aa)
STRN4Striatin 4. (760 aa)
EGFRReceptor protein-tyrosine kinase. (1210 aa)
MAPK1Mitogen-activated protein kinase. (330 aa)
CDKN1BCyclin dependent kinase inhibitor 1B. (198 aa)
GNG3Guanine nucleotide-binding protein subunit gamma; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction. (75 aa)
ENSRROP00000027148Cyclin N-terminal domain-containing protein. (74 aa)
ERASES cell expressed Ras. (233 aa)
FOSFos proto-oncogene, AP-1 transcription factor subunit. (380 aa)
MMP2Matrix metallopeptidase 2. (660 aa)
XPO1Exportin 1. (1071 aa)
PIK3R3Phosphoinositide-3-kinase regulatory subunit 3. (461 aa)
GNB5G protein subunit beta 5. (403 aa)
PRMT1Methyltransf_25 domain-containing protein; Belongs to the class I-like SAM-binding methyltransferase superfamily. Protein arginine N-methyltransferase family. (371 aa)
MAPK3Mitogen-activated protein kinase; Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. MAP kinase subfamily. (379 aa)
HSPB1SHSP domain-containing protein; Belongs to the small heat shock protein (HSP20) family. (205 aa)
ESR2Estrogen receptor 2. (530 aa)
GNG4Guanine nucleotide-binding protein subunit gamma; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction. (75 aa)
PTK2Protein tyrosine kinase 2; Belongs to the protein kinase superfamily. Tyr protein kinase family. (1109 aa)
KRASKRAS proto-oncogene, GTPase. (189 aa)
LOC104665116Uncharacterized protein; Belongs to the class I-like SAM-binding methyltransferase superfamily. Protein arginine N-methyltransferase family. (255 aa)
GNB4G protein subunit beta 4. (340 aa)
ENSRROP00000035890G protein gamma domain-containing protein. (68 aa)
STRNStriatin. (787 aa)
ENSRROP00000034142annotation not available (59 aa)
HSP90AA1HATPase_c domain-containing protein. (657 aa)
ELK1Uncharacterized protein. (428 aa)
BCL2BCL2 apoptosis regulator. (239 aa)
GNG5Guanine nucleotide-binding protein subunit gamma; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction. (68 aa)
Your Current Organism:
Rhinopithecus roxellana
NCBI taxonomy Id: 61622
Other names: Pygathrix roxellana, R. roxellana, golden snub-nosed monkey
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