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AGO2 | Protein argonaute-2; Required for RNA-mediated gene silencing (RNAi) by the RNA- induced silencing complex (RISC). The 'minimal RISC' appears to include AGO2 bound to a short guide RNA such as a microRNA (miRNA) or short interfering RNA (siRNA). These guide RNAs direct RISC to complementary mRNAs that are targets for RISC-mediated gene silencing. The precise mechanism of gene silencing depends on the degree of complementarity between the miRNA or siRNA and its target. Binding of RISC to a perfectly complementary mRNA generally results in silencing due to endonucleolytic cleavage of the [...] (865 aa) | ||||
ABCG5 | ATP binding cassette subfamily G member 5. (651 aa) | ||||
ANGPTL3 | Angiopoietin like 3. (460 aa) | ||||
LOC104682414 | WD_REPEATS_REGION domain-containing protein. (489 aa) | ||||
ENSRROP00000005469 | Uncharacterized protein. (53 aa) | ||||
HDAC3 | Histone deacetylase 3; Responsible for the deacetylation of lysine residues on the N-terminal part of the core histones (H2A, H2B, H3 and H4), and some other non-histone substrates. Histone deacetylation gives a tag for epigenetic repression and plays an important role in transcriptional regulation, cell cycle progression and developmental events. Histone deacetylases act via the formation of large multiprotein complexes. (428 aa) | ||||
KDM4A | Uncharacterized protein. (1064 aa) | ||||
ENSRROP00000007230 | Uncharacterized protein. (193 aa) | ||||
NRIP1 | Nuclear receptor interacting protein 1. (1155 aa) | ||||
APOE | Apolipoprotein E; APOE is an apolipoprotein, a protein associating with lipid particles, that mainly functions in lipoprotein-mediated lipid transport between organs via the plasma and interstitial fluids. APOE is a core component of plasma lipoproteins and is involved in their production, conversion and clearance. Apoliproteins are amphipathic molecules that interact both with lipids of the lipoprotein particle core and the aqueous environment of the plasma. As such, APOE associates with chylomicrons, chylomicron remnants, very low density lipoproteins (VLDL) and intermediate density [...] (317 aa) | ||||
ARL4C | ADP ribosylation factor like GTPase 4C; Belongs to the small GTPase superfamily. Arf family. (202 aa) | ||||
TBL1X | Transducin beta like 1 X-linked. (575 aa) | ||||
ENSRROP00000012874 | Uncharacterized protein. (205 aa) | ||||
TNRC6B | Trinucleotide repeat containing adaptor 6B. (1832 aa) | ||||
APOC4 | Uncharacterized protein. (127 aa) | ||||
FABP6 | Fatty acid binding protein 6. (163 aa) | ||||
ENSRROP00000017874 | Uncharacterized protein; Belongs to the fatty acid desaturase type 1 family. (348 aa) | ||||
PLIN1 | Perilipin; Belongs to the perilipin family. (522 aa) | ||||
MYLIP | Myosin regulatory light chain interacting protein. (462 aa) | ||||
AGO4 | Protein argonaute-4; Required for RNA-mediated gene silencing (RNAi). Binds to short RNAs such as microRNAs (miRNAs) and represses the translation of mRNAs which are complementary to them. Lacks endonuclease activity and does not appear to cleave target mRNAs. (828 aa) | ||||
ARL4A | ADP ribosylation factor like GTPase 4A. (200 aa) | ||||
EP300 | E1A binding protein p300. (2413 aa) | ||||
EEPD1 | Endonuclease/exonuclease/phosphatase family domain containing 1. (569 aa) | ||||
ABCA1 | ATP binding cassette subfamily A member 1. (2261 aa) | ||||
SREBF1 | Sterol regulatory element binding transcription factor 1. (1177 aa) | ||||
NCOR1 | Nuclear receptor corepressor 1. (2440 aa) | ||||
SCD | Uncharacterized protein; Belongs to the fatty acid desaturase type 1 family. (359 aa) | ||||
LOC104673462 | Uncharacterized protein. (130 aa) | ||||
CETP | Cholesteryl ester transfer protein; Involved in the transfer of neutral lipids, including cholesteryl ester and triglyceride, among lipoprotein particles. Allows the net movement of cholesteryl ester from high density lipoproteins/HDL to triglyceride-rich very low density lipoproteins/VLDL, and the equimolar transport of triglyceride from VLDL to HDL; Belongs to the BPI/LBP/Plunc superfamily. BPI/LBP family. (493 aa) | ||||
PCK1 | Phosphoenolpyruvate carboxykinase 1. (622 aa) | ||||
NR1H2 | Nuclear receptor subfamily 1 group H member 2. (461 aa) | ||||
GPS2 | G protein pathway suppressor 2. (327 aa) | ||||
KDM1A | Lysine-specific histone demethylase; Histone demethylase that demethylates both 'Lys-4' (H3K4me) and 'Lys-9' (H3K9me) of histone H3, thereby acting as a coactivator or a corepressor, depending on the context. Acts by oxidizing the substrate by FAD to generate the corresponding imine that is subsequently hydrolyzed. Acts as a corepressor by mediating demethylation of H3K4me, a specific tag for epigenetic transcriptional activation. Demethylates both mono- (H3K4me1) and di-methylated (H3K4me2) H3K4me; Belongs to the flavin monoamine oxidase family. (876 aa) | ||||
ENSRROP00000035150 | Uncharacterized protein; Belongs to the small GTPase superfamily. Arf family. (200 aa) | ||||
MOV10 | Mov10 RISC complex RNA helicase. (1003 aa) | ||||
RXRB | Retinoid X receptor beta. (542 aa) | ||||
KDM3A | Lysine demethylase 3A. (1322 aa) | ||||
NCOA1 | Nuclear receptor coactivator. (1441 aa) | ||||
PLTP | Phospholipid transfer protein. (493 aa) | ||||
AGO3 | Protein argonaute-3; Required for RNA-mediated gene silencing (RNAi). Binds to short RNAs such as microRNAs (miRNAs) and represses the translation of mRNAs which are complementary to them. Lacks endonuclease activity and does not appear to cleave target mRNAs. (860 aa) | ||||
NCOR2 | Nuclear receptor corepressor 2. (2522 aa) | ||||
RXRA | Retinoid X receptor alpha. (481 aa) | ||||
TBL1XR1 | Transducin beta like 1 X-linked receptor 1. (514 aa) | ||||
FASN | Fatty acid synthase. (2504 aa) | ||||
AGO1 | Argonaute RISC component 1; Belongs to the argonaute family. (857 aa) | ||||
ABCG8 | ATP binding cassette subfamily G member 8. (673 aa) | ||||
APOD | Apolipoprotein D. (215 aa) | ||||
ABCG1 | ATP binding cassette subfamily G member 1. (677 aa) | ||||
NR1H3 | Nuclear receptor subfamily 1 group H member 3. (511 aa) | ||||
APOC2 | Apolipoprotein C2. (119 aa) |