33 items (Rhinopithecus roxellana) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	ABCA6	ATP binding cassette subfamily A member 6. (1618 aa)
	PLXNA4	Plexin A4. (1869 aa)
	G6PC	Glucose-6-phosphatase; Belongs to the glucose-6-phosphatase family. (357 aa)
	PPARGC1A	PPARG coactivator 1 alpha. (798 aa)
	FOXO3	Forkhead box O3. (617 aa)
	SOD2	Superoxide dismutase; Destroys radicals which are normally produced within the cells and which are toxic to biological systems. Belongs to the iron/manganese superoxide dismutase family. (222 aa)
	SMAD3	Mothers against decapentaplegic homolog. (480 aa)
	CAT	Catalase; Occurs in almost all aerobically respiring organisms and serves to protect cells from the toxic effects of hydrogen peroxide. (527 aa)
	POMC	Proopiomelanocortin. (251 aa)
	SIN3A	SIN3 transcription regulator family member A. (1273 aa)
	SMAD4	Mothers against decapentaplegic homolog. (552 aa)
	AGRP	Agouti related neuropeptide. (132 aa)
	ENSRROP00000040307	Josephin domain-containing protein. (101 aa)
	FOXO1	Forkhead box O1. (585 aa)
	IGFBP1	Insulin like growth factor binding protein 1. (283 aa)
	TRIM63	Tripartite motif containing 63. (383 aa)
	FOXO6	Forkhead box O6. (365 aa)
	INS	Insulin; Insulin decreases blood glucose concentration. It increases cell permeability to monosaccharides, amino acids and fatty acids. It accelerates glycolysis, the pentose phosphate cycle, and glycogen synthesis in liver. (110 aa)
	FBXO32	F-box protein 32. (360 aa)
	PCK1	Phosphoenolpyruvate carboxykinase 1. (622 aa)
	ENSRROP00000031184	Fork-head domain-containing protein. (193 aa)
	SREBF1	Sterol regulatory element binding transcription factor 1. (1177 aa)
	LOC104677352	Histone deacetylase 1; Responsible for the deacetylation of lysine residues on the N-terminal part of the core histones (H2A, H2B, H3 and H4). Histone deacetylation gives a tag for epigenetic repression and plays an important role in transcriptional regulation, cell cycle progression and developmental events. Histone deacetylases act via the formation of large multiprotein complexes. (484 aa)
	ATXN3	Ataxin 3. (365 aa)
	SIRT3	NAD-dependent protein deacetylase; NAD-dependent protein deacetylase. (399 aa)
	RETN	Resistin. (104 aa)
	FOXO4	Forkhead box O4. (505 aa)
	GCK	Phosphotransferase. (466 aa)
	SMAD2	Mothers against decapentaplegic homolog. (392 aa)
	ENSRROP00000019405	Hist_deacetyl domain-containing protein. (352 aa)
	HDAC2	Histone deacetylase 2; Responsible for the deacetylation of lysine residues on the N-terminal part of the core histones (H2A, H2B, H3 and H4). Histone deacetylation gives a tag for epigenetic repression and plays an important role in transcriptional regulation, cell cycle progression and developmental events. Histone deacetylases act via the formation of large multiprotein complexes. (488 aa)
	HDAC1	Histone deacetylase 1; Responsible for the deacetylation of lysine residues on the N-terminal part of the core histones (H2A, H2B, H3 and H4). Histone deacetylation gives a tag for epigenetic repression and plays an important role in transcriptional regulation, cell cycle progression and developmental events. Histone deacetylases act via the formation of large multiprotein complexes. (477 aa)
	NR3C1	Nuclear receptor subfamily 3 group C member 1. (778 aa)

Your Current Organism:

Rhinopithecus roxellana

NCBI taxonomy Id: 61622
Other names: Pygathrix roxellana, R. roxellana, golden snub-nosed monkey

Send network to Cytoscape

Export your current network:

... as a bitmap image:

download

file format is 'PNG': portable network graphic

... as a high-resolution bitmap:

download

same PNG format, but at higher resolution

... as a vector graphic:

download

SVG: scalable vector graphic - can be opened and edited in Illustrator, CorelDraw, Dia, etc

... as short tabular text output:

download

TSV: tab separated values - can be opened in Excel and Cytoscape (lists only one-way edges: A-B)

... as tabular text output:

download

TSV: tab separated values - can be opened in Excel (lists reciprocal edges: A-B,B-A)

... as an XML summary:

download

structured XML interaction data, according to the 'PSI-MI' data standard

... protein node degrees:

download

node degree of proteins in your network (given the current score cut-off)

... network coordinates:

download

a flat-file format describing the coordinates and colors of nodes in the network

... protein sequences:

download

MFA: multi-fasta format - containing the aminoacid sequences in the network

... protein annotations:

download

a tab-delimited file describing the names, domains and descriptions of proteins in your network

... functional annotations:

download

a tab-delimited file containing all known functional terms of protiens in your network

Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
AGRP	FOXO1	ENSRROP00000041199	ENSRROP00000036657	Agouti related neuropeptide.	Forkhead box O1.	0.621
AGRP	FOXO3	ENSRROP00000041199	ENSRROP00000008097	Agouti related neuropeptide.	Forkhead box O3.	0.419
AGRP	INS	ENSRROP00000041199	ENSRROP00000034403	Agouti related neuropeptide.	Insulin; Insulin decreases blood glucose concentration. It increases cell permeability to monosaccharides, amino acids and fatty acids. It accelerates glycolysis, the pentose phosphate cycle, and glycogen synthesis in liver.	0.594
AGRP	POMC	ENSRROP00000041199	ENSRROP00000044919	Agouti related neuropeptide.	Proopiomelanocortin.	0.735
ATXN3	ENSRROP00000031184	ENSRROP00000028735	ENSRROP00000031184	Ataxin 3.	Fork-head domain-containing protein.	0.521
ATXN3	FOXO4	ENSRROP00000028735	ENSRROP00000023907	Ataxin 3.	Forkhead box O4.	0.521
CAT	FOXO3	ENSRROP00000000697	ENSRROP00000008097	Catalase; Occurs in almost all aerobically respiring organisms and serves to protect cells from the toxic effects of hydrogen peroxide.	Forkhead box O3.	0.490
CAT	SOD2	ENSRROP00000000697	ENSRROP00000007858	Catalase; Occurs in almost all aerobically respiring organisms and serves to protect cells from the toxic effects of hydrogen peroxide.	Superoxide dismutase; Destroys radicals which are normally produced within the cells and which are toxic to biological systems. Belongs to the iron/manganese superoxide dismutase family.	0.957
ENSRROP00000019405	HDAC2	ENSRROP00000019405	ENSRROP00000017767	Hist_deacetyl domain-containing protein.	Histone deacetylase 2; Responsible for the deacetylation of lysine residues on the N-terminal part of the core histones (H2A, H2B, H3 and H4). Histone deacetylation gives a tag for epigenetic repression and plays an important role in transcriptional regulation, cell cycle progression and developmental events. Histone deacetylases act via the formation of large multiprotein complexes.	0.920
ENSRROP00000019405	NR3C1	ENSRROP00000019405	ENSRROP00000008135	Hist_deacetyl domain-containing protein.	Nuclear receptor subfamily 3 group C member 1.	0.500
ENSRROP00000019405	SIN3A	ENSRROP00000019405	ENSRROP00000043335	Hist_deacetyl domain-containing protein.	SIN3 transcription regulator family member A.	0.926
ENSRROP00000019405	SMAD2	ENSRROP00000019405	ENSRROP00000023441	Hist_deacetyl domain-containing protein.	Mothers against decapentaplegic homolog.	0.616
ENSRROP00000019405	SMAD3	ENSRROP00000019405	ENSRROP00000006108	Hist_deacetyl domain-containing protein.	Mothers against decapentaplegic homolog.	0.593
ENSRROP00000019405	SMAD4	ENSRROP00000019405	ENSRROP00000043301	Hist_deacetyl domain-containing protein.	Mothers against decapentaplegic homolog.	0.594
ENSRROP00000031184	ATXN3	ENSRROP00000031184	ENSRROP00000028735	Fork-head domain-containing protein.	Ataxin 3.	0.521
ENSRROP00000031184	ENSRROP00000040307	ENSRROP00000031184	ENSRROP00000040307	Fork-head domain-containing protein.	Josephin domain-containing protein.	0.521
ENSRROP00000031184	FOXO1	ENSRROP00000031184	ENSRROP00000036657	Fork-head domain-containing protein.	Forkhead box O1.	0.423
ENSRROP00000031184	FOXO3	ENSRROP00000031184	ENSRROP00000008097	Fork-head domain-containing protein.	Forkhead box O3.	0.437
ENSRROP00000031184	FOXO4	ENSRROP00000031184	ENSRROP00000023907	Fork-head domain-containing protein.	Forkhead box O4.	0.749
ENSRROP00000031184	INS	ENSRROP00000031184	ENSRROP00000034403	Fork-head domain-containing protein.	Insulin; Insulin decreases blood glucose concentration. It increases cell permeability to monosaccharides, amino acids and fatty acids. It accelerates glycolysis, the pentose phosphate cycle, and glycogen synthesis in liver.	0.411