STRINGSTRING
ITPR1 ITPR1 GNG8 GNG8 ENSRROP00000045475 ENSRROP00000045475 DPEP1 DPEP1 PLCG2 PLCG2 PLCG1 PLCG1 LOC104673929 LOC104673929 MAPK14 MAPK14 PRKAR1A PRKAR1A AHCYL1 AHCYL1 ADCY9 ADCY9 ITPR2 ITPR2 CREB1 CREB1 ENSRROP00000022234 ENSRROP00000022234 SYK SYK SRC SRC GNAI1 GNAI1 CD247 CD247 GNAT3 GNAT3 FYN FYN CD163 CD163 ADORA2B ADORA2B PRKAR1B PRKAR1B YES1 YES1 GNAI3 GNAI3 DPEP2 DPEP2 SCART1 SCART1 GNB1 GNB1 RHBDF1 RHBDF1 CYSLTR2 CYSLTR2 PLK2 PLK2 ADCY2 ADCY2 MYH9 MYH9 LOC104671265 LOC104671265 PRKACA PRKACA GNG13 GNG13 DPEP3 DPEP3 PRKX PRKX GNAI2 GNAI2 ADCY1 ADCY1 GNG7 GNG7 GNAZ GNAZ ENSRROP00000007762 ENSRROP00000007762 LYN LYN CD3G CD3G GNB3 GNB3 PRKACB PRKACB ENSRROP00000005502 ENSRROP00000005502 GNGT2 GNGT2 ADCY5 ADCY5 GNG2 GNG2 GNGT1 GNGT1 IL6 IL6 ADCY4 ADCY4 CYSLTR1 CYSLTR1 ADCY8 ADCY8 GNG3 GNG3 GGT5 GGT5 ADAM17 ADAM17 LOC104660851 LOC104660851 GNB5 GNB5 GGT1 GGT1 GNG4 GNG4 FGR FGR LOC104670100 LOC104670100 ENSRROP00000034142 ENSRROP00000034142 ENSRROP00000034614 ENSRROP00000034614 RHBDF2 RHBDF2 GNG5 GNG5 ITPR3 ITPR3 PRKAR2B PRKAR2B GNB4 GNB4 ADCY7 ADCY7 PRKAR2A PRKAR2A GNG11 GNG11 GNAS GNAS GNB2 GNB2 ADCY6 ADCY6 ADCY3 ADCY3 FURIN FURIN HCK HCK GNG12 GNG12 LOC104677425 LOC104677425 IL10 IL10
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
ITPR1Inositol 1,4,5-trisphosphate receptor type 1. (2714 aa)
GNG8Guanine nucleotide-binding protein subunit gamma; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction. (73 aa)
ENSRROP00000045475G protein gamma domain-containing protein. (58 aa)
DPEP1Dipeptidase; Belongs to the metallo-dependent hydrolases superfamily. Peptidase M19 family. (411 aa)
PLCG21-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma; Mediates the production of the second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3). Plays an important role in the regulation of intracellular signaling cascades. (1265 aa)
PLCG11-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma; Mediates the production of the second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3). Plays an important role in the regulation of intracellular signaling cascades. (1303 aa)
LOC104673929Uncharacterized protein. (252 aa)
MAPK14Mitogen-activated protein kinase. (360 aa)
PRKAR1AProtein kinase cAMP-dependent type I regulatory subunit alpha. (381 aa)
AHCYL1Adenosylhomocysteinase like 1; Belongs to the adenosylhomocysteinase family. (530 aa)
ADCY9Adenylate cyclase 9; Belongs to the adenylyl cyclase class-4/guanylyl cyclase family. (1353 aa)
ITPR2Inositol 1,4,5-trisphosphate receptor type 2. (2700 aa)
CREB1cAMP responsive element binding protein 1. (341 aa)
ENSRROP00000022234Guanine nucleotide-binding protein subunit gamma; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction. (59 aa)
SYKTyrosine-protein kinase. (635 aa)
SRCTyrosine-protein kinase. (540 aa)
GNAI1G protein subunit alpha i1. (253 aa)
CD247CD247 molecule. (173 aa)
GNAT3Uncharacterized protein. (196 aa)
FYNTyrosine-protein kinase. (537 aa)
CD163CD163 molecule. (1141 aa)
ADORA2BAdenosine receptor A2; Receptor for adenosine. The activity of this receptor is mediated by G proteins which activate adenylyl cyclase. Belongs to the G-protein coupled receptor 1 family. (331 aa)
PRKAR1BProtein kinase cAMP-dependent type I regulatory subunit beta. (381 aa)
YES1Tyrosine-protein kinase. (543 aa)
GNAI3G protein subunit alpha i3. (354 aa)
DPEP2Dipeptidase; Belongs to the metallo-dependent hydrolases superfamily. Peptidase M19 family. (484 aa)
SCART1Scavenger receptor family member expressed on T cells 1. (943 aa)
GNB1G protein subunit beta 1. (340 aa)
RHBDF1Rhomboid 5 homolog 1. (878 aa)
CYSLTR2Cysteinyl leukotriene receptor 2. (338 aa)
PLK2Serine/threonine-protein kinase PLK. (685 aa)
ADCY2Adenylate cyclase type 2; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling. (1052 aa)
MYH9Myosin heavy chain 9; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Myosin family. (1960 aa)
LOC104671265Uncharacterized protein. (225 aa)
PRKACAProtein kinase cAMP-activated catalytic subunit alpha; Belongs to the protein kinase superfamily. (351 aa)
GNG13G protein subunit gamma 13. (67 aa)
DPEP3Dipeptidase; Belongs to the metallo-dependent hydrolases superfamily. Peptidase M19 family. (513 aa)
PRKXUncharacterized protein; Belongs to the protein kinase superfamily. (321 aa)
GNAI2G protein subunit alpha i2. (355 aa)
ADCY1Adenylate cyclase type 1; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling. (1075 aa)
GNG7Guanine nucleotide-binding protein subunit gamma; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction. (68 aa)
GNAZG protein subunit alpha z. (355 aa)
ENSRROP00000007762Guanine nucleotide-binding protein subunit gamma; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction. (69 aa)
LYNTyrosine-protein kinase. (491 aa)
CD3GCD3g molecule. (181 aa)
GNB3G protein subunit beta 3. (340 aa)
PRKACBProtein kinase cAMP-activated catalytic subunit beta; Belongs to the protein kinase superfamily. (398 aa)
ENSRROP00000005502Protein kinase domain-containing protein. (325 aa)
GNGT2Guanine nucleotide-binding protein subunit gamma; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction. (101 aa)
ADCY5Adenylate cyclase 5; Belongs to the adenylyl cyclase class-4/guanylyl cyclase family. (864 aa)
GNG2Guanine nucleotide-binding protein subunit gamma; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction. (110 aa)
GNGT1Guanine nucleotide-binding protein subunit gamma; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction. (89 aa)
IL6Interleukin 6. (214 aa)
ADCY4Adenylate cyclase type 4; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling. (1077 aa)
CYSLTR1Cysteinyl leukotriene receptor 1. (337 aa)
ADCY8Adenylate cyclase type 8; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling. (1043 aa)
GNG3Guanine nucleotide-binding protein subunit gamma; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction. (75 aa)
GGT5Uncharacterized protein. (322 aa)
ADAM17ADAM metallopeptidase domain 17. (824 aa)
LOC104660851Uncharacterized protein. (288 aa)
GNB5G protein subunit beta 5. (403 aa)
GGT1Uncharacterized protein. (430 aa)
GNG4Guanine nucleotide-binding protein subunit gamma; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction. (75 aa)
FGRTyrosine-protein kinase. (529 aa)
LOC104670100Uncharacterized protein. (351 aa)
ENSRROP00000034142annotation not available (59 aa)
ENSRROP00000034614Tyrosine-protein kinase. (465 aa)
RHBDF2Rhomboid 5 homolog 2. (836 aa)
GNG5Guanine nucleotide-binding protein subunit gamma; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction. (68 aa)
ITPR3Inositol 1,4,5-trisphosphate receptor type 3. (2703 aa)
PRKAR2BProtein kinase cAMP-dependent type II regulatory subunit beta. (429 aa)
GNB4G protein subunit beta 4. (340 aa)
ADCY7Adenylate cyclase type 7; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling. (1095 aa)
PRKAR2AProtein kinase cAMP-dependent type II regulatory subunit alpha. (404 aa)
GNG11Guanine nucleotide-binding protein subunit gamma; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction. (74 aa)
GNASGNAS complex locus. (1041 aa)
GNB2G protein subunit beta 2. (340 aa)
ADCY6Adenylate cyclase 6; Belongs to the adenylyl cyclase class-4/guanylyl cyclase family. (603 aa)
ADCY3Adenylate cyclase type 3; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling. (1147 aa)
FURINFurin, paired basic amino acid cleaving enzyme; Belongs to the peptidase S8 family. (830 aa)
HCKTyrosine-protein kinase. (591 aa)
GNG12Guanine nucleotide-binding protein subunit gamma; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction. (72 aa)
LOC104677425Uncharacterized protein. (157 aa)
IL10Interleukin 10. (178 aa)
Your Current Organism:
Rhinopithecus roxellana
NCBI taxonomy Id: 61622
Other names: Pygathrix roxellana, R. roxellana, golden snub-nosed monkey
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