25 items (Rhinopithecus roxellana) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	CISH	Cytokine inducible SH2 containing protein. (275 aa)
	SOCS1	Suppressor of cytokine signaling 1. (215 aa)
	STAT5A	Signal transducer and activator of transcription. (905 aa)
	SOCS3	Suppressor of cytokine signaling 3. (225 aa)
	LYN	Tyrosine-protein kinase. (491 aa)
	LOC104675501	Growth hormone-like protein 2. (217 aa)
	PRLR	Prolactin receptor; This is a receptor for the anterior pituitary hormone prolactin. (619 aa)
	JAK2	Tyrosine-protein kinase. (1094 aa)
	STAT5B	Signal transducer and activator of transcription. (787 aa)
	GHR	Growth hormone receptor. (639 aa)
	LOC104675458	Uncharacterized protein. (202 aa)
	IRS2	Insulin receptor substrate 2. (1006 aa)
	PRL	Prolactin. (228 aa)
	LOC104675500	Uncharacterized protein. (236 aa)
	STAT3	Signal transducer and activator of transcription. (802 aa)
	GH1	Growth hormone-like protein 1. (217 aa)
	MAPK1	Mitogen-activated protein kinase. (330 aa)
	PTPN6	Tyrosine-protein phosphatase non-receptor type; Belongs to the protein-tyrosine phosphatase family. Non- receptor class 2 subfamily. (623 aa)
	ADAM17	ADAM metallopeptidase domain 17. (824 aa)
	MAPK3	Mitogen-activated protein kinase; Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. MAP kinase subfamily. (379 aa)
	STAT1	Signal transducer and activator of transcription. (787 aa)
	PTPN1	Tyrosine-protein phosphatase non-receptor type. (465 aa)
	ENSRROP00000038248	Uncharacterized protein. (216 aa)
	SOCS2	Suppressor of cytokine signaling 2. (198 aa)
	LOC104675456	Uncharacterized protein. (160 aa)

Your Current Organism:

Rhinopithecus roxellana

NCBI taxonomy Id: 61622
Other names: Pygathrix roxellana, R. roxellana, golden snub-nosed monkey

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
ADAM17	GHR	ENSRROP00000029317	ENSRROP00000014529	ADAM metallopeptidase domain 17.	Growth hormone receptor.	0.468
CISH	GHR	ENSRROP00000014785	ENSRROP00000014529	Cytokine inducible SH2 containing protein.	Growth hormone receptor.	0.518
CISH	JAK2	ENSRROP00000014785	ENSRROP00000011033	Cytokine inducible SH2 containing protein.	Tyrosine-protein kinase.	0.692
CISH	PRLR	ENSRROP00000014785	ENSRROP00000008452	Cytokine inducible SH2 containing protein.	Prolactin receptor; This is a receptor for the anterior pituitary hormone prolactin.	0.924
CISH	SOCS2	ENSRROP00000014785	ENSRROP00000043963	Cytokine inducible SH2 containing protein.	Suppressor of cytokine signaling 2.	0.445
CISH	SOCS3	ENSRROP00000014785	ENSRROP00000005957	Cytokine inducible SH2 containing protein.	Suppressor of cytokine signaling 3.	0.435
CISH	STAT1	ENSRROP00000014785	ENSRROP00000033613	Cytokine inducible SH2 containing protein.	Signal transducer and activator of transcription.	0.952
CISH	STAT3	ENSRROP00000014785	ENSRROP00000018412	Cytokine inducible SH2 containing protein.	Signal transducer and activator of transcription.	0.956
CISH	STAT5A	ENSRROP00000014785	ENSRROP00000001812	Cytokine inducible SH2 containing protein.	Signal transducer and activator of transcription.	0.950
CISH	STAT5B	ENSRROP00000014785	ENSRROP00000012514	Cytokine inducible SH2 containing protein.	Signal transducer and activator of transcription.	0.953
ENSRROP00000038248	GH1	ENSRROP00000038248	ENSRROP00000018618	Uncharacterized protein.	Growth hormone-like protein 1.	0.900
ENSRROP00000038248	GHR	ENSRROP00000038248	ENSRROP00000014529	Uncharacterized protein.	Growth hormone receptor.	0.967
ENSRROP00000038248	JAK2	ENSRROP00000038248	ENSRROP00000011033	Uncharacterized protein.	Tyrosine-protein kinase.	0.791
ENSRROP00000038248	LOC104675458	ENSRROP00000038248	ENSRROP00000017081	Uncharacterized protein.	Uncharacterized protein.	0.900
ENSRROP00000038248	LOC104675500	ENSRROP00000038248	ENSRROP00000017616	Uncharacterized protein.	Uncharacterized protein.	0.901
ENSRROP00000038248	PRL	ENSRROP00000038248	ENSRROP00000017384	Uncharacterized protein.	Prolactin.	0.961
ENSRROP00000038248	PRLR	ENSRROP00000038248	ENSRROP00000008452	Uncharacterized protein.	Prolactin receptor; This is a receptor for the anterior pituitary hormone prolactin.	0.857
GH1	ENSRROP00000038248	ENSRROP00000018618	ENSRROP00000038248	Growth hormone-like protein 1.	Uncharacterized protein.	0.900
GH1	GHR	ENSRROP00000018618	ENSRROP00000014529	Growth hormone-like protein 1.	Growth hormone receptor.	0.989
GH1	JAK2	ENSRROP00000018618	ENSRROP00000011033	Growth hormone-like protein 1.	Tyrosine-protein kinase.	0.791