(21 nodes) Terpenoid backbone biosynthesis network (Rhinopithecus roxellana)

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Your Input:
	IDI2	Isopentenyl-diphosphate delta isomerase 2. (154 aa)
	ACAT2	Uncharacterized protein; Belongs to the thiolase-like superfamily. Thiolase family. (397 aa)
	GGPS1	Geranylgeranyl diphosphate synthase 1; Belongs to the FPP/GGPP synthase family. (300 aa)
	PCYOX1	Prenylcysteine oxidase 1. (504 aa)
	PDSS1	Decaprenyl diphosphate synthase subunit 1; Belongs to the FPP/GGPP synthase family. (415 aa)
	HMGCS2	3-hydroxy-3-methylglutaryl coenzyme A synthase; This enzyme condenses acetyl-CoA with acetoacetyl-CoA to form HMG-CoA, which is the substrate for HMG-CoA reductase. (508 aa)
	NUS1	NUS1 dehydrodolichyl diphosphate synthase subunit. (293 aa)
	MVD	Diphosphomevalonate decarboxylase; Performs the first committed step in the biosynthesis of isoprenes. (401 aa)
	ACAT1	Acetyl-CoA acetyltransferase 1; Belongs to the thiolase-like superfamily. Thiolase family. (427 aa)
	RCE1	Ras converting CAAX endopeptidase 1. (329 aa)
	PMVK	Phosphomevalonate kinase. (192 aa)
	FNTB	Protein farnesyltransferase subunit beta; Essential subunit of the farnesyltransferase complex. Catalyzes the transfer of a farnesyl moiety from farnesyl diphosphate to a cysteine at the fourth position from the C-terminus of several proteins having the C-terminal sequence Cys-aliphatic-aliphatic-X. (463 aa)
	FDPS	Farnesyl diphosphate synthase; Belongs to the FPP/GGPP synthase family. (419 aa)
	HMGCR	3-hydroxy-3-methylglutaryl coenzyme A reductase. (888 aa)
	ICMT	Protein-S-isoprenylcysteine O-methyltransferase. (255 aa)
	PDSS2	Uncharacterized protein. (203 aa)
	MVK	Mevalonate kinase; Catalyzes the phosphorylation of mevalonate to mevalonate 5- phosphate, a key step in isoprenoid and cholesterol biosynthesis. Belongs to the GHMP kinase family. Mevalonate kinase subfamily. (418 aa)
	IDI1	Isopentenyl-diphosphate delta isomerase 1. (280 aa)
	DHDDS	Alkyl transferase; Belongs to the UPP synthase family. (333 aa)
	HMGCS1	3-hydroxy-3-methylglutaryl coenzyme A synthase; This enzyme condenses acetyl-CoA with acetoacetyl-CoA to form HMG-CoA, which is the substrate for HMG-CoA reductase. (520 aa)
	FNTA	Farnesyltransferase, CAAX box, alpha. (379 aa)

Your Current Organism:

Rhinopithecus roxellana

NCBI taxonomy Id: 61622
Other names: Pygathrix roxellana, R. roxellana, golden snub-nosed monkey

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
ACAT1	ACAT2	ENSRROP00000022356	ENSRROP00000013002	Acetyl-CoA acetyltransferase 1; Belongs to the thiolase-like superfamily. Thiolase family.	Uncharacterized protein; Belongs to the thiolase-like superfamily. Thiolase family.	0.912
ACAT1	HMGCR	ENSRROP00000022356	ENSRROP00000032591	Acetyl-CoA acetyltransferase 1; Belongs to the thiolase-like superfamily. Thiolase family.	3-hydroxy-3-methylglutaryl coenzyme A reductase.	0.469
ACAT1	HMGCS1	ENSRROP00000022356	ENSRROP00000040810	Acetyl-CoA acetyltransferase 1; Belongs to the thiolase-like superfamily. Thiolase family.	3-hydroxy-3-methylglutaryl coenzyme A synthase; This enzyme condenses acetyl-CoA with acetoacetyl-CoA to form HMG-CoA, which is the substrate for HMG-CoA reductase.	0.991
ACAT1	HMGCS2	ENSRROP00000022356	ENSRROP00000021076	Acetyl-CoA acetyltransferase 1; Belongs to the thiolase-like superfamily. Thiolase family.	3-hydroxy-3-methylglutaryl coenzyme A synthase; This enzyme condenses acetyl-CoA with acetoacetyl-CoA to form HMG-CoA, which is the substrate for HMG-CoA reductase.	0.991
ACAT1	MVD	ENSRROP00000022356	ENSRROP00000021800	Acetyl-CoA acetyltransferase 1; Belongs to the thiolase-like superfamily. Thiolase family.	Diphosphomevalonate decarboxylase; Performs the first committed step in the biosynthesis of isoprenes.	0.609
ACAT1	MVK	ENSRROP00000022356	ENSRROP00000036455	Acetyl-CoA acetyltransferase 1; Belongs to the thiolase-like superfamily. Thiolase family.	Mevalonate kinase; Catalyzes the phosphorylation of mevalonate to mevalonate 5- phosphate, a key step in isoprenoid and cholesterol biosynthesis. Belongs to the GHMP kinase family. Mevalonate kinase subfamily.	0.704
ACAT2	ACAT1	ENSRROP00000013002	ENSRROP00000022356	Uncharacterized protein; Belongs to the thiolase-like superfamily. Thiolase family.	Acetyl-CoA acetyltransferase 1; Belongs to the thiolase-like superfamily. Thiolase family.	0.912
ACAT2	HMGCR	ENSRROP00000013002	ENSRROP00000032591	Uncharacterized protein; Belongs to the thiolase-like superfamily. Thiolase family.	3-hydroxy-3-methylglutaryl coenzyme A reductase.	0.535
ACAT2	HMGCS1	ENSRROP00000013002	ENSRROP00000040810	Uncharacterized protein; Belongs to the thiolase-like superfamily. Thiolase family.	3-hydroxy-3-methylglutaryl coenzyme A synthase; This enzyme condenses acetyl-CoA with acetoacetyl-CoA to form HMG-CoA, which is the substrate for HMG-CoA reductase.	0.989
ACAT2	HMGCS2	ENSRROP00000013002	ENSRROP00000021076	Uncharacterized protein; Belongs to the thiolase-like superfamily. Thiolase family.	3-hydroxy-3-methylglutaryl coenzyme A synthase; This enzyme condenses acetyl-CoA with acetoacetyl-CoA to form HMG-CoA, which is the substrate for HMG-CoA reductase.	0.988
ACAT2	IDI1	ENSRROP00000013002	ENSRROP00000036900	Uncharacterized protein; Belongs to the thiolase-like superfamily. Thiolase family.	Isopentenyl-diphosphate delta isomerase 1.	0.400
ACAT2	IDI2	ENSRROP00000013002	ENSRROP00000004832	Uncharacterized protein; Belongs to the thiolase-like superfamily. Thiolase family.	Isopentenyl-diphosphate delta isomerase 2.	0.400
ACAT2	MVD	ENSRROP00000013002	ENSRROP00000021800	Uncharacterized protein; Belongs to the thiolase-like superfamily. Thiolase family.	Diphosphomevalonate decarboxylase; Performs the first committed step in the biosynthesis of isoprenes.	0.609
ACAT2	MVK	ENSRROP00000013002	ENSRROP00000036455	Uncharacterized protein; Belongs to the thiolase-like superfamily. Thiolase family.	Mevalonate kinase; Catalyzes the phosphorylation of mevalonate to mevalonate 5- phosphate, a key step in isoprenoid and cholesterol biosynthesis. Belongs to the GHMP kinase family. Mevalonate kinase subfamily.	0.705
DHDDS	FDPS	ENSRROP00000037482	ENSRROP00000030905	Alkyl transferase; Belongs to the UPP synthase family.	Farnesyl diphosphate synthase; Belongs to the FPP/GGPP synthase family.	0.953
DHDDS	FNTA	ENSRROP00000037482	ENSRROP00000044001	Alkyl transferase; Belongs to the UPP synthase family.	Farnesyltransferase, CAAX box, alpha.	0.944
DHDDS	FNTB	ENSRROP00000037482	ENSRROP00000030560	Alkyl transferase; Belongs to the UPP synthase family.	Protein farnesyltransferase subunit beta; Essential subunit of the farnesyltransferase complex. Catalyzes the transfer of a farnesyl moiety from farnesyl diphosphate to a cysteine at the fourth position from the C-terminus of several proteins having the C-terminal sequence Cys-aliphatic-aliphatic-X.	0.957
DHDDS	GGPS1	ENSRROP00000037482	ENSRROP00000016150	Alkyl transferase; Belongs to the UPP synthase family.	Geranylgeranyl diphosphate synthase 1; Belongs to the FPP/GGPP synthase family.	0.961
DHDDS	HMGCR	ENSRROP00000037482	ENSRROP00000032591	Alkyl transferase; Belongs to the UPP synthase family.	3-hydroxy-3-methylglutaryl coenzyme A reductase.	0.592
DHDDS	HMGCS1	ENSRROP00000037482	ENSRROP00000040810	Alkyl transferase; Belongs to the UPP synthase family.	3-hydroxy-3-methylglutaryl coenzyme A synthase; This enzyme condenses acetyl-CoA with acetoacetyl-CoA to form HMG-CoA, which is the substrate for HMG-CoA reductase.	0.408