68 items (Rhinopithecus roxellana) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	RPP25L	Ribonuclease P/MRP subunit p25 like. (163 aa)
	LOC104657745	Uncharacterized protein. (611 aa)
	NAT10	RNA cytidine acetyltransferase; RNA cytidine acetyltransferase with specificity toward both 18S rRNA and tRNAs. Catalyzes the formation of N(4)-acetylcytidine (ac4C) in 18S rRNA. Required for early nucleolar cleavages of precursor rRNA at sites A0, A1 and A2 during 18S rRNA synthesis. Catalyzes the formation of ac4C in serine and leucine tRNAs. Requires the tRNA- binding adapter protein THUMPD1 for full tRNA acetyltransferase activity but not for 18S rRNA acetylation. (1026 aa)
	POP1	POP1 homolog, ribonuclease P/MRP subunit. (1024 aa)
	FBL	Fibrillarin. (335 aa)
	GNL2	Nucleolar GTP-binding protein 2; GTPase that associates with pre-60S ribosomal subunits in the nucleolus and is required for their nuclear export and maturation. Belongs to the TRAFAC class YlqF/YawG GTPase family. NOG2 subfamily. (731 aa)
	NOP56	NOP56 ribonucleoprotein. (594 aa)
	REXO1	RNA exonuclease 1 homolog. (1388 aa)
	IMP3	IMP U3 small nucleolar ribonucleoprotein 3. (184 aa)
	MDN1	Midasin; Nuclear chaperone required for maturation and nuclear export of pre-60S ribosome subunits; Belongs to the midasin family. (5599 aa)
	NXT1	Nuclear transport factor 2 like export factor 1. (140 aa)
	TBL3	Transducin beta like 3. (808 aa)
	EIF6	Eukaryotic translation initiation factor 6; Binds to the 60S ribosomal subunit and prevents its association with the 40S ribosomal subunit to form the 80S initiation complex in the cytoplasm. Behaves as a stimulatory translation initiation factor downstream insulin/growth factors. Is also involved in ribosome biogenesis. Associates with pre-60S subunits in the nucleus and is involved in its nuclear export. Cytoplasmic release of TIF6 from 60S subunits and nuclear relocalization is promoted by a RACK1 (RACK1)- dependent protein kinase C activity. In tissues responsive to insulin, contro [...] (245 aa)
	WDR3	WD repeat domain 3. (943 aa)
	DROSHA	Drosha ribonuclease III. (1374 aa)
	GAR1	H/ACA ribonucleoprotein complex subunit; Required for ribosome biogenesis. Part of a complex which catalyzes pseudouridylation of rRNA. This involves the isomerization of uridine such that the ribose is subsequently attached to C5, instead of the normal N1. Pseudouridine ("psi") residues may serve to stabilize the conformation of rRNAs. (217 aa)
	POP7	Ribonuclease P protein subunit p20; Component of ribonuclease P, a ribonucleoprotein complex that generates mature tRNA molecules by cleaving their 5'-ends. Also a component of the MRP ribonuclease complex, which cleaves pre-rRNA sequences; Belongs to the histone-like Alba family. (140 aa)
	UTP14A	UTP14A small subunit processome component. (771 aa)
	POP4	Ribonuclease P protein subunit p29; Component of ribonuclease P, a ribonucleoprotein complex that generates mature tRNA molecules by cleaving their 5'-ends. (220 aa)
	RCL1	RNA terminal phosphate cyclase like 1. (373 aa)
	GNL3	G protein nucleolar 3. (549 aa)
	GTPBP4	Nucleolar GTP-binding protein 1; Involved in the biogenesis of the 60S ribosomal subunit. Belongs to the TRAFAC class OBG-HflX-like GTPase superfamily. OBG GTPase family. NOG subfamily. (634 aa)
	RPP38	Uncharacterized protein. (144 aa)
	UTP4	UTP4 small subunit processome component. (517 aa)
	EFL1	Elongation factor like GTPase 1. (1093 aa)
	NXF3	Nuclear RNA export factor 3. (530 aa)
	IMP4	IMP U3 small nucleolar ribonucleoprotein 4. (291 aa)
	PWP2	Uncharacterized protein. (918 aa)
	WDR75	WD repeat domain 75. (830 aa)
	AK6	Adenylate kinase isoenzyme 6; Broad-specificity nucleoside monophosphate (NMP) kinase that catalyzes the reversible transfer of the terminal phosphate group between nucleoside triphosphates and monophosphates. May have a role in nuclear energy homeostasis. Has also ATPase activity. May be involved in regulation of Cajal body (CB) formation; Belongs to the adenylate kinase family. AK6 subfamily. (172 aa)
	EMG1	EMG1 N1-specific pseudouridine methyltransferase. (244 aa)
	NOB1	RNA-binding protein NOB1; May play a role in mRNA degradation. Belongs to the NOB1 family. (412 aa)
	MPHOSPH10	U3 small nucleolar ribonucleoprotein protein MPP10; Component of the 60-80S U3 small nucleolar ribonucleoprotein (U3 snoRNP). Required for the early cleavages during pre-18S ribosomal RNA processing; Belongs to the MPP10 family. (771 aa)
	TCOF1	Treacle ribosome biogenesis factor 1. (1523 aa)
	UTP15	UTP15 small subunit processome component. (518 aa)
	REXO5	RNA exonuclease 5. (771 aa)
	SPATA5	Spermatogenesis associated 5. (893 aa)
	WDR43	WD repeat domain 43. (689 aa)
	NMD3	60S ribosomal export protein NMD3; Acts as an adapter for the XPO1/CRM1-mediated export of the 60S ribosomal subunit; Belongs to the NMD3 family. (529 aa)
	NXT2	Nuclear transport factor 2 like export factor 2. (197 aa)
	RIOK1	Serine/threonine-protein kinase RIO1; Belongs to the protein kinase superfamily. RIO-type Ser/Thr kinase family. (567 aa)
	RRP7A	Ribosomal RNA processing 7 homolog A. (281 aa)
	UTP6	UTP6 small subunit processome component. (598 aa)
	GNL3L	G protein nucleolar 3 like. (582 aa)
	FCF1	FCF1 rRNA-processing protein. (198 aa)
	HEATR1	HEAT repeat containing 1. (2144 aa)
	LSG1	Large 60S subunit nuclear export GTPase 1. (657 aa)
	NOP58	NOP58 ribonucleoprotein. (540 aa)
	XPO1	Exportin 1. (1071 aa)
	REXO2	RNA exonuclease 2. (237 aa)
	NOL6	Nucleolar protein 6. (1157 aa)
	RPP40	Ribonuclease P/MRP subunit p40. (363 aa)
	NVL	Uncharacterized protein. (855 aa)
	RIOK2	RIO kinase 2. (552 aa)
	BMS1	BMS1 ribosome biogenesis factor. (1265 aa)
	UTP18	UTP18 small subunit processome component. (596 aa)
	RBM28	RNA binding motif protein 28. (762 aa)
	SBDS	Uncharacterized protein. (250 aa)
	WDR36	WD repeat domain 36. (758 aa)
	SNU13	Ribonucloprotein; Common component of the spliceosome and rRNA processing machinery; Belongs to the eukaryotic ribosomal protein eL8 family. (132 aa)
	CSNK2A1	Protein kinase domain-containing protein; Belongs to the protein kinase superfamily. (391 aa)
	NOP10	Uncharacterized protein. (64 aa)
	NXF1	Nuclear RNA export factor 1. (619 aa)
	ENSRROP00000042033	GTP-binding nuclear protein Ran; GTP-binding protein involved in nucleocytoplasmic transport. Required for the import of protein into the nucleus and also for RNA export. Involved in chromatin condensation and control of cell cycle. Belongs to the small GTPase superfamily. Ran family. (220 aa)
	XRN1	5'-3' exoribonuclease 1. (926 aa)
	XRN2	5'-3' exoribonuclease; Possesses 5'->3' exoribonuclease activity. May promote termination of transcription by RNA polymerase II. (1063 aa)
	CSNK2B	Uncharacterized protein. (298 aa)
	DKC1	Dyskerin pseudouridine synthase 1. (514 aa)

Your Current Organism:

Rhinopithecus roxellana

NCBI taxonomy Id: 61622
Other names: Pygathrix roxellana, R. roxellana, golden snub-nosed monkey

Send network to Cytoscape

Export your current network:

... as a bitmap image:

download

file format is 'PNG': portable network graphic

... as a high-resolution bitmap:

download

same PNG format, but at higher resolution

... as a vector graphic:

download

SVG: scalable vector graphic - can be opened and edited in Illustrator, CorelDraw, Dia, etc

... as short tabular text output:

download

TSV: tab separated values - can be opened in Excel and Cytoscape (lists only one-way edges: A-B)

... as tabular text output:

download

TSV: tab separated values - can be opened in Excel (lists reciprocal edges: A-B,B-A)

... as an XML summary:

download

structured XML interaction data, according to the 'PSI-MI' data standard

... protein node degrees:

download

node degree of proteins in your network (given the current score cut-off)

... network coordinates:

download

a flat-file format describing the coordinates and colors of nodes in the network

... protein sequences:

download

MFA: multi-fasta format - containing the aminoacid sequences in the network

... protein annotations:

download

a tab-delimited file describing the names, domains and descriptions of proteins in your network

... functional annotations:

download

a tab-delimited file containing all known functional terms of protiens in your network

Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
AK6	HEATR1	ENSRROP00000017437	ENSRROP00000026907	Adenylate kinase isoenzyme 6; Broad-specificity nucleoside monophosphate (NMP) kinase that catalyzes the reversible transfer of the terminal phosphate group between nucleoside triphosphates and monophosphates. May have a role in nuclear energy homeostasis. Has also ATPase activity. May be involved in regulation of Cajal body (CB) formation; Belongs to the adenylate kinase family. AK6 subfamily.	HEAT repeat containing 1.	0.411
AK6	NOB1	ENSRROP00000017437	ENSRROP00000018765	Adenylate kinase isoenzyme 6; Broad-specificity nucleoside monophosphate (NMP) kinase that catalyzes the reversible transfer of the terminal phosphate group between nucleoside triphosphates and monophosphates. May have a role in nuclear energy homeostasis. Has also ATPase activity. May be involved in regulation of Cajal body (CB) formation; Belongs to the adenylate kinase family. AK6 subfamily.	RNA-binding protein NOB1; May play a role in mRNA degradation. Belongs to the NOB1 family.	0.661
AK6	POP4	ENSRROP00000017437	ENSRROP00000008960	Adenylate kinase isoenzyme 6; Broad-specificity nucleoside monophosphate (NMP) kinase that catalyzes the reversible transfer of the terminal phosphate group between nucleoside triphosphates and monophosphates. May have a role in nuclear energy homeostasis. Has also ATPase activity. May be involved in regulation of Cajal body (CB) formation; Belongs to the adenylate kinase family. AK6 subfamily.	Ribonuclease P protein subunit p29; Component of ribonuclease P, a ribonucleoprotein complex that generates mature tRNA molecules by cleaving their 5'-ends.	0.413
AK6	PWP2	ENSRROP00000017437	ENSRROP00000015537	Adenylate kinase isoenzyme 6; Broad-specificity nucleoside monophosphate (NMP) kinase that catalyzes the reversible transfer of the terminal phosphate group between nucleoside triphosphates and monophosphates. May have a role in nuclear energy homeostasis. Has also ATPase activity. May be involved in regulation of Cajal body (CB) formation; Belongs to the adenylate kinase family. AK6 subfamily.	Uncharacterized protein.	0.441
AK6	RIOK1	ENSRROP00000017437	ENSRROP00000025751	Adenylate kinase isoenzyme 6; Broad-specificity nucleoside monophosphate (NMP) kinase that catalyzes the reversible transfer of the terminal phosphate group between nucleoside triphosphates and monophosphates. May have a role in nuclear energy homeostasis. Has also ATPase activity. May be involved in regulation of Cajal body (CB) formation; Belongs to the adenylate kinase family. AK6 subfamily.	Serine/threonine-protein kinase RIO1; Belongs to the protein kinase superfamily. RIO-type Ser/Thr kinase family.	0.535
AK6	RIOK2	ENSRROP00000017437	ENSRROP00000030987	Adenylate kinase isoenzyme 6; Broad-specificity nucleoside monophosphate (NMP) kinase that catalyzes the reversible transfer of the terminal phosphate group between nucleoside triphosphates and monophosphates. May have a role in nuclear energy homeostasis. Has also ATPase activity. May be involved in regulation of Cajal body (CB) formation; Belongs to the adenylate kinase family. AK6 subfamily.	RIO kinase 2.	0.568
AK6	WDR43	ENSRROP00000017437	ENSRROP00000024233	Adenylate kinase isoenzyme 6; Broad-specificity nucleoside monophosphate (NMP) kinase that catalyzes the reversible transfer of the terminal phosphate group between nucleoside triphosphates and monophosphates. May have a role in nuclear energy homeostasis. Has also ATPase activity. May be involved in regulation of Cajal body (CB) formation; Belongs to the adenylate kinase family. AK6 subfamily.	WD repeat domain 43.	0.400
BMS1	DKC1	ENSRROP00000032995	ENSRROP00000043476	BMS1 ribosome biogenesis factor.	Dyskerin pseudouridine synthase 1.	0.536
BMS1	EMG1	ENSRROP00000032995	ENSRROP00000017730	BMS1 ribosome biogenesis factor.	EMG1 N1-specific pseudouridine methyltransferase.	0.769
BMS1	FBL	ENSRROP00000032995	ENSRROP00000003147	BMS1 ribosome biogenesis factor.	Fibrillarin.	0.809
BMS1	FCF1	ENSRROP00000032995	ENSRROP00000026874	BMS1 ribosome biogenesis factor.	FCF1 rRNA-processing protein.	0.698
BMS1	GNL2	ENSRROP00000032995	ENSRROP00000003617	BMS1 ribosome biogenesis factor.	Nucleolar GTP-binding protein 2; GTPase that associates with pre-60S ribosomal subunits in the nucleolus and is required for their nuclear export and maturation. Belongs to the TRAFAC class YlqF/YawG GTPase family. NOG2 subfamily.	0.797
BMS1	GNL3	ENSRROP00000032995	ENSRROP00000011499	BMS1 ribosome biogenesis factor.	G protein nucleolar 3.	0.556
BMS1	GNL3L	ENSRROP00000032995	ENSRROP00000026385	BMS1 ribosome biogenesis factor.	G protein nucleolar 3 like.	0.556
BMS1	GTPBP4	ENSRROP00000032995	ENSRROP00000013024	BMS1 ribosome biogenesis factor.	Nucleolar GTP-binding protein 1; Involved in the biogenesis of the 60S ribosomal subunit. Belongs to the TRAFAC class OBG-HflX-like GTPase superfamily. OBG GTPase family. NOG subfamily.	0.779
BMS1	HEATR1	ENSRROP00000032995	ENSRROP00000026907	BMS1 ribosome biogenesis factor.	HEAT repeat containing 1.	0.927
BMS1	IMP3	ENSRROP00000032995	ENSRROP00000005984	BMS1 ribosome biogenesis factor.	IMP U3 small nucleolar ribonucleoprotein 3.	0.802
BMS1	IMP4	ENSRROP00000032995	ENSRROP00000015172	BMS1 ribosome biogenesis factor.	IMP U3 small nucleolar ribonucleoprotein 4.	0.713
BMS1	LSG1	ENSRROP00000032995	ENSRROP00000027832	BMS1 ribosome biogenesis factor.	Large 60S subunit nuclear export GTPase 1.	0.714
BMS1	MPHOSPH10	ENSRROP00000032995	ENSRROP00000020235	BMS1 ribosome biogenesis factor.	U3 small nucleolar ribonucleoprotein protein MPP10; Component of the 60-80S U3 small nucleolar ribonucleoprotein (U3 snoRNP). Required for the early cleavages during pre-18S ribosomal RNA processing; Belongs to the MPP10 family.	0.919