STRINGSTRING
DDX5 DDX5 SYF2 SYF2 HSPA1L HSPA1L LOC104660005 LOC104660005 ACIN1 ACIN1 SRSF7 SRSF7 SLU7 SLU7 LOC104663122 LOC104663122 SF3B6 SF3B6 LOC104657389 LOC104657389 LSM6 LSM6 SRSF8 SRSF8 PRPF3 PRPF3 SNRPD1 SNRPD1 HSPA8-2 HSPA8-2 HSPA6 HSPA6 SNRNP40 SNRNP40 DHX38 DHX38 HNRNPA3 HNRNPA3 DDX23 DDX23 CDC5L CDC5L PRPF38B PRPF38B SF3B4 SF3B4 PUF60 PUF60 SRSF4 SRSF4 DDX46 DDX46 CDC40 CDC40 NCBP1 NCBP1 DDX42 DDX42 SRSF6 SRSF6 MAGOH MAGOH LSM2 LSM2 TRA2A TRA2A HNRNPA1 HNRNPA1 THOC3 THOC3 U2AF2 U2AF2 SNRPD3 SNRPD3 SNRPB2 SNRPB2 SF3B1 SF3B1 HNRNPK HNRNPK DHX16 DHX16 SNRPE SNRPE ENSRROP00000016206 ENSRROP00000016206 ZMAT2 ZMAT2 PQBP1 PQBP1 PRPF38A PRPF38A SNRPG-2 SNRPG-2 PRPF40A PRPF40A LSM3 LSM3 SNRNP70 SNRNP70 SF3A3 SF3A3 SNW1 SNW1 LSM7 LSM7 LOC104671082 LOC104671082 SF3A2 SF3A2 SF3B2 SF3B2 TXNL4A TXNL4A SNRPD2 SNRPD2 WBP11 WBP11 TRA2B TRA2B RBM25 RBM25 DHX8 DHX8 SNRPB SNRPB BUD31 BUD31 SF3B5 SF3B5 CWC15 CWC15 SNRNP200 SNRNP200 PRPF8 PRPF8 HNRNPM HNRNPM SNRPA1 SNRPA1 PRPF31 PRPF31 PHF5A PHF5A MAGOHB MAGOHB DHX15 DHX15 DDX39B DDX39B USP39 USP39 LSM8 LSM8 CCDC12 CCDC12 PRPF4 PRPF4 RBM8A RBM8A CRNKL1 CRNKL1 PRPF18 PRPF18 CHERP CHERP XAB2 XAB2 PRPF6 PRPF6 LOC104673734 LOC104673734 SNRPC SNRPC SRSF1 SRSF1 SRSF9 SRSF9 CTNNBL1 CTNNBL1 EIF4A3 EIF4A3 SRSF2 SRSF2 SNU13 SNU13 RP9 RP9 SNRPA SNRPA EFTUD2 EFTUD2 SRSF10 SRSF10 SRSF5 SRSF5 LOC104659628 LOC104659628 U2SURP U2SURP TCERG1 TCERG1 RBM17 RBM17 PPIH PPIH AQR AQR BCAS2 BCAS2 SRSF3 SRSF3 SF3A1 SF3A1 PPIE PPIE SMNDC1 SMNDC1 THOC1 THOC1 PLRG1 PLRG1 SART1 SART1 PPIL1 PPIL1 ALYREF ALYREF SNRPG SNRPG SF3B3 SF3B3 LSM4 LSM4
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
DDX5DEAD-box helicase 5; Belongs to the DEAD box helicase family. (614 aa)
SYF2SYF2 pre-mRNA splicing factor. (243 aa)
HSPA1LHeat shock protein family A (Hsp70) member 1 like; Belongs to the heat shock protein 70 family. (641 aa)
LOC104660005U6 snRNA-associated Sm-like protein LSm5; Plays a role in U6 snRNP assembly and function. Binds to the 3' end of U6 snRNA. (91 aa)
ACIN1Apoptotic chromatin condensation inducer 1. (1341 aa)
SRSF7Serine and arginine rich splicing factor 7. (238 aa)
SLU7SLU7 homolog, splicing factor. (586 aa)
LOC104663122Uncharacterized protein. (376 aa)
SF3B6Splicing factor 3b subunit 6. (125 aa)
LOC104657389Sm domain-containing protein. (86 aa)
LSM6LSM6 homolog, U6 small nuclear RNA and mRNA degradation associated. (80 aa)
SRSF8Serine and arginine rich splicing factor 8. (287 aa)
PRPF3Pre-mRNA processing factor 3. (683 aa)
SNRPD1Small nuclear ribonucleoprotein Sm D1; Plays role in pre-mRNA splicing as core component of the SMN- Sm complex that mediates spliceosomal snRNP assembly and as component of the spliceosomal U1, U2, U4 and U5 small nuclear ribonucleoproteins (snRNPs), the building blocks of the spliceosome. Component of both the pre-catalytic spliceosome B complex and activated spliceosome C complexes. Is also a component of the minor U12 spliceosome. May act as a charged protein scaffold to promote snRNP assembly or strengthen snRNP-snRNP interactions through non-specific electrostatic contacts with RNA. (130 aa)
HSPA8-2Uncharacterized protein. (129 aa)
HSPA6Heat shock protein family A (Hsp70) member 6; Belongs to the heat shock protein 70 family. (608 aa)
SNRNP40Small nuclear ribonucleoprotein U5 subunit 40. (357 aa)
DHX38DEAH-box helicase 38. (1227 aa)
HNRNPA3Uncharacterized protein. (356 aa)
DDX23DEAD-box helicase 23. (820 aa)
CDC5LCell division cycle 5 like. (802 aa)
PRPF38BPre-mRNA processing factor 38B. (546 aa)
SF3B4Splicing factor 3b subunit 4. (424 aa)
PUF60Poly(U) binding splicing factor 60. (559 aa)
SRSF4Serine and arginine rich splicing factor 4. (494 aa)
DDX46DEAD-box helicase 46. (1031 aa)
CDC40Cell division cycle 40. (579 aa)
NCBP1Nuclear cap binding protein subunit 1. (790 aa)
DDX42DEAD-box helicase 42. (937 aa)
SRSF6Serine and arginine rich splicing factor 6. (343 aa)
MAGOHMago homolog, exon junction complex subunit. (283 aa)
LSM2U6 snRNA-associated Sm-like protein LSm2; Binds specifically to the 3'-terminal U-tract of U6 snRNA. (95 aa)
TRA2ATransformer 2 alpha homolog. (282 aa)
HNRNPA1Uncharacterized protein. (372 aa)
THOC3THO complex 3. (351 aa)
U2AF2U2 snRNP auxiliary factor large subunit; Necessary for the splicing of pre-mRNA. Belongs to the splicing factor SR family. (414 aa)
SNRPD3Small nuclear ribonucleoprotein Sm D3; Plays role in pre-mRNA splicing as core component of the SMN- Sm complex that mediates spliceosomal snRNP assembly and as component of the spliceosomal U1, U2, U4 and U5 small nuclear ribonucleoproteins (snRNPs), the building blocks of the spliceosome. Component of both the pre-catalytic spliceosome B complex and activated spliceosome C complexes. Is also a component of the minor U12 spliceosome. As part of the U7 snRNP it is involved in histone pre-mRNA 3'-end processing. (126 aa)
SNRPB2Small nuclear ribonucleoprotein polypeptide B2. (225 aa)
SF3B1Splicing factor 3b subunit 1. (1304 aa)
HNRNPKUncharacterized protein. (464 aa)
DHX16DEAH-box helicase 16. (1044 aa)
SNRPESmall nuclear ribonucleoprotein E; Plays role in pre-mRNA splicing as core component of the SMN- Sm complex that mediates spliceosomal snRNP assembly and as component of the spliceosomal U1, U2, U4 and U5 small nuclear ribonucleoproteins (snRNPs), the building blocks of the spliceosome. Component of both the pre-catalytic spliceosome B complex and activated spliceosome C complexes. Is also a component of the minor U12 spliceosome. As part of the U7 snRNP it is involved in histone 3'-end processing. May indirectly play a role in hair development. (92 aa)
ENSRROP00000016206RRM domain-containing protein. (381 aa)
ZMAT2Zinc finger matrin-type 2. (199 aa)
PQBP1Polyglutamine binding protein 1. (265 aa)
PRPF38APRP38_assoc domain-containing protein. (312 aa)
SNRPG-2Small nuclear ribonucleoprotein G; Plays role in pre-mRNA splicing as core component of the SMN- Sm complex that mediates spliceosomal snRNP assembly and as component of the spliceosomal U1, U2, U4 and U5 small nuclear ribonucleoproteins (snRNPs), the building blocks of the spliceosome. Component of both the pre-catalytic spliceosome B complex and activated spliceosome C complexes. Is also a component of the minor U12 spliceosome. As part of the U7 snRNP it is involved in histone 3'-end processing. (74 aa)
PRPF40APre-mRNA processing factor 40 homolog A. (930 aa)
LSM3U6 snRNA-associated Sm-like protein LSm3; Binds specifically to the 3'-terminal U-tract of U6 snRNA. (102 aa)
SNRNP70Small nuclear ribonucleoprotein U1 subunit 70. (437 aa)
SF3A3Splicing factor 3a subunit 3. (504 aa)
SNW1SNW domain containing 1. (536 aa)
LSM7LSM7 homolog, U6 small nuclear RNA and mRNA degradation associated. (103 aa)
LOC104671082RRM domain-containing protein. (334 aa)
SF3A2Splicing factor 3a subunit 2. (470 aa)
SF3B2Splicing factor 3b subunit 2. (895 aa)
TXNL4AThioredoxin-like protein; Plays role in pre-mRNA splicing. Belongs to the DIM1 family. (142 aa)
SNRPD2Small nuclear ribonucleoprotein Sm D2; Plays role in pre-mRNA splicing as core component of the SMN- Sm complex that mediates spliceosomal snRNP assembly and as component of the spliceosomal U1, U2, U4 and U5 small nuclear ribonucleoproteins (snRNPs), the building blocks of the spliceosome. Component of both the pre-catalytic spliceosome B complex and activated spliceosome C complexes. Is also a component of the minor U12 spliceosome. (118 aa)
WBP11Uncharacterized protein. (641 aa)
TRA2BTransformer 2 beta homolog. (288 aa)
RBM25RNA binding motif protein 25. (843 aa)
DHX8DEAH-box helicase 8. (1220 aa)
SNRPBSmall nuclear ribonucleoprotein-associated protein. (240 aa)
BUD31BUD31 homolog. (144 aa)
SF3B5Splicing factor 3B subunit 5; Belongs to the SF3B5 family. (86 aa)
CWC15CWC15 spliceosome associated protein homolog. (229 aa)
SNRNP200Small nuclear ribonucleoprotein U5 subunit 200. (2146 aa)
PRPF8Pre-mRNA processing factor 8. (2339 aa)
HNRNPMUncharacterized protein. (730 aa)
SNRPA1Small nuclear ribonucleoprotein polypeptide A. (255 aa)
PRPF31Pre-mRNA processing factor 31. (499 aa)
PHF5APHD finger protein 5A. (110 aa)
MAGOHBMago homolog B, exon junction complex subunit. (148 aa)
DHX15DEAH-box helicase 15. (795 aa)
DDX39BDExD-box helicase 39B. (428 aa)
USP39Ubiquitin specific peptidase 39. (569 aa)
LSM8U6 snRNA-associated Sm-like protein LSm8; Plays role in pre-mRNA splicing as component of the U4/U6-U5 tri-snRNP complex that is involved in spliceosome assembly, and as component of the precatalytic spliceosome (spliceosome B complex). The heptameric LSM2-8 complex binds specifically to the 3'-terminal U-tract of U6 snRNA. (96 aa)
CCDC12Coiled-coil domain containing 12. (166 aa)
PRPF4Pre-mRNA processing factor 4. (543 aa)
RBM8ARNA-binding protein 8A; Core component of the splicing-dependent multiprotein exon junction complex (EJC) deposited at splice junctions on mRNAs. (174 aa)
CRNKL1Crooked neck pre-mRNA splicing factor 1. (687 aa)
PRPF18Pre-mRNA processing factor 18. (351 aa)
CHERPCalcium homeostasis endoplasmic reticulum protein. (927 aa)
XAB2XPA binding protein 2. (860 aa)
PRPF6Pre-mRNA processing factor 6. (940 aa)
LOC104673734RRM domain-containing protein. (380 aa)
SNRPCU1 small nuclear ribonucleoprotein C; Component of the spliceosomal U1 snRNP, which is essential for recognition of the pre-mRNA 5' splice-site and the subsequent assembly of the spliceosome. SNRPC/U1-C is directly involved in initial 5' splice-site recognition for both constitutive and regulated alternative splicing. The interaction with the 5' splice-site seems to precede base-pairing between the pre-mRNA and the U1 snRNA. Stimulates commitment or early (E) complex formation by stabilizing the base pairing of the 5' end of the U1 snRNA and the 5' splice-site region. Belongs to the U1 [...] (180 aa)
SRSF1Uncharacterized protein. (253 aa)
SRSF9Serine and arginine rich splicing factor 9. (191 aa)
CTNNBL1DUF1716 domain-containing protein. (563 aa)
EIF4A3Eukaryotic translation initiation factor 4A3; Belongs to the DEAD box helicase family. (411 aa)
SRSF2Serine and arginine rich splicing factor 2. (221 aa)
SNU13Ribonucloprotein; Common component of the spliceosome and rRNA processing machinery; Belongs to the eukaryotic ribosomal protein eL8 family. (132 aa)
RP9RP9 pre-mRNA splicing factor. (194 aa)
SNRPASmall nuclear ribonucleoprotein polypeptide A. (282 aa)
EFTUD2Elongation factor Tu GTP binding domain containing 2. (972 aa)
SRSF10Serine and arginine rich splicing factor 10. (262 aa)
SRSF5Serine and arginine rich splicing factor 5. (272 aa)
LOC104659628Uncharacterized protein. (145 aa)
U2SURPU2 snRNP associated SURP domain containing. (1029 aa)
TCERG1Transcription elongation regulator 1. (1092 aa)
RBM17RNA binding motif protein 17. (401 aa)
PPIHPeptidyl-prolyl cis-trans isomerase; PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides; Belongs to the cyclophilin-type PPIase family. (177 aa)
AQRRNA helicase aquarius; Intron-binding spliceosomal protein required to link pre-mRNA splicing and snoRNP (small nucleolar ribonucleoprotein) biogenesis. Plays a key role in position-dependent assembly of intron-encoded box C/D small snoRNP, splicing being required for snoRNP assembly. May act by helping the folding of the snoRNA sequence. Binds to intron of pre- mRNAs in a sequence-independent manner, contacting the region between snoRNA and the branchpoint of introns (40 nucleotides upstream of the branchpoint) during the late stages of splicing. (1492 aa)
BCAS2BCAS2 pre-mRNA processing factor. (209 aa)
SRSF3Serine and arginine rich splicing factor 3. (164 aa)
SF3A1Splicing factor 3a subunit 1. (793 aa)
PPIEPeptidyl-prolyl cis-trans isomerase E; Catalyzes the cis-trans isomerization of proline imidic peptide bonds in proteins; Belongs to the cyclophilin-type PPIase family. PPIase E subfamily. (320 aa)
SMNDC1Tudor domain-containing protein. (238 aa)
THOC1THO complex 1. (657 aa)
PLRG1Pleiotropic regulator 1. (514 aa)
SART1Spliceosome associated factor 1, recruiter of U4/U6.U5 tri-snRNP. (800 aa)
PPIL1Peptidyl-prolyl cis-trans isomerase; PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides; Belongs to the cyclophilin-type PPIase family. (166 aa)
ALYREFAly/REF export factor. (279 aa)
SNRPGSmall nuclear ribonucleoprotein G; Plays role in pre-mRNA splicing as core component of the SMN- Sm complex that mediates spliceosomal snRNP assembly and as component of the spliceosomal U1, U2, U4 and U5 small nuclear ribonucleoproteins (snRNPs), the building blocks of the spliceosome. Component of both the pre-catalytic spliceosome B complex and activated spliceosome C complexes. Is also a component of the minor U12 spliceosome. As part of the U7 snRNP it is involved in histone 3'-end processing. (76 aa)
SF3B3Splicing factor 3b subunit 3. (1217 aa)
LSM4U6 snRNA-associated Sm-like protein LSm4; Binds specifically to the 3'-terminal U-tract of U6 snRNA. (231 aa)
Your Current Organism:
Rhinopithecus roxellana
NCBI taxonomy Id: 61622
Other names: Pygathrix roxellana, R. roxellana, golden snub-nosed monkey
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