(20 nodes) Protein export network (Rhinopithecus roxellana)

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	SEC61G	SEC61 translocon gamma subunit. (68 aa)
	SRP14	Uncharacterized protein. (138 aa)
	SRP9	Signal recognition particle 9 kDa protein; Signal-recognition-particle assembly has a crucial role in targeting secretory proteins to the rough endoplasmic reticulum membrane. SRP9 together with SRP14 and the Alu portion of the SRP RNA, constitutes the elongation arrest domain of SRP. The complex of SRP9 and SRP14 is required for SRP RNA binding. (86 aa)
	HSPA5	Heat shock protein family A (Hsp70) member 5; Belongs to the heat shock protein 70 family. (654 aa)
	SRPRA	SRP receptor subunit alpha. (639 aa)
	SRPRB	SRP receptor subunit beta. (271 aa)
	OXA1L	OXA1L mitochondrial inner membrane protein. (440 aa)
	IMMP2L	Inner mitochondrial membrane peptidase subunit 2. (95 aa)
	SEC63	SEC63 homolog, protein translocation regulator. (760 aa)
	SRP72	Signal recognition particle subunit SRP72; Signal-recognition-particle assembly has a crucial role in targeting secretory proteins to the rough endoplasmic reticulum membrane; Belongs to the SRP72 family. (671 aa)
	SEC11A	Signal peptidase complex catalytic subunit SEC11. (187 aa)
	SPCS3	Signal peptidase complex subunit 3. (180 aa)
	SEC62	SEC62 homolog, preprotein translocation factor. (399 aa)
	IMMP1L	Mitochondrial inner membrane protease subunit. (166 aa)
	SEC61B	Protein transport protein Sec61 subunit beta; Necessary for protein translocation in the endoplasmic reticulum. (96 aa)
	SRP54	Signal recognition particle 54 kDa protein; Binds to the signal sequence of presecretory protein when they emerge from the ribosomes and transfers them to TRAM (translocating chain-associating membrane protein). Belongs to the GTP-binding SRP family. SRP54 subfamily. (515 aa)
	SRP68	Signal recognition particle subunit SRP68; Signal-recognition-particle assembly has a crucial role in targeting secretory proteins to the rough endoplasmic reticulum membrane; Belongs to the SRP68 family. (622 aa)
	SEC11C	Signal peptidase complex catalytic subunit SEC11. (192 aa)
	SEC61A1	Plug_translocon domain-containing protein. (482 aa)
	SPCS1	Signal peptidase complex subunit 1. (169 aa)

Your Current Organism:

Rhinopithecus roxellana

NCBI taxonomy Id: 61622
Other names: Pygathrix roxellana, R. roxellana, golden snub-nosed monkey

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
HSPA5	SEC61A1	ENSRROP00000008593	ENSRROP00000042151	Heat shock protein family A (Hsp70) member 5; Belongs to the heat shock protein 70 family.	Plug_translocon domain-containing protein.	0.576
HSPA5	SEC61B	ENSRROP00000008593	ENSRROP00000034725	Heat shock protein family A (Hsp70) member 5; Belongs to the heat shock protein 70 family.	Protein transport protein Sec61 subunit beta; Necessary for protein translocation in the endoplasmic reticulum.	0.448
HSPA5	SEC62	ENSRROP00000008593	ENSRROP00000034212	Heat shock protein family A (Hsp70) member 5; Belongs to the heat shock protein 70 family.	SEC62 homolog, preprotein translocation factor.	0.574
HSPA5	SEC63	ENSRROP00000008593	ENSRROP00000023364	Heat shock protein family A (Hsp70) member 5; Belongs to the heat shock protein 70 family.	SEC63 homolog, protein translocation regulator.	0.908
HSPA5	SRP54	ENSRROP00000008593	ENSRROP00000035628	Heat shock protein family A (Hsp70) member 5; Belongs to the heat shock protein 70 family.	Signal recognition particle 54 kDa protein; Binds to the signal sequence of presecretory protein when they emerge from the ribosomes and transfers them to TRAM (translocating chain-associating membrane protein). Belongs to the GTP-binding SRP family. SRP54 subfamily.	0.463
HSPA5	SRPRB	ENSRROP00000008593	ENSRROP00000012467	Heat shock protein family A (Hsp70) member 5; Belongs to the heat shock protein 70 family.	SRP receptor subunit beta.	0.437
IMMP1L	SPCS1	ENSRROP00000034284	ENSRROP00000042851	Mitochondrial inner membrane protease subunit.	Signal peptidase complex subunit 1.	0.719
IMMP1L	SPCS3	ENSRROP00000034284	ENSRROP00000032398	Mitochondrial inner membrane protease subunit.	Signal peptidase complex subunit 3.	0.715
IMMP2L	SPCS1	ENSRROP00000017633	ENSRROP00000042851	Inner mitochondrial membrane peptidase subunit 2.	Signal peptidase complex subunit 1.	0.719
IMMP2L	SPCS3	ENSRROP00000017633	ENSRROP00000032398	Inner mitochondrial membrane peptidase subunit 2.	Signal peptidase complex subunit 3.	0.715
OXA1L	SEC61A1	ENSRROP00000014512	ENSRROP00000042151	OXA1L mitochondrial inner membrane protein.	Plug_translocon domain-containing protein.	0.823
OXA1L	SRP54	ENSRROP00000014512	ENSRROP00000035628	OXA1L mitochondrial inner membrane protein.	Signal recognition particle 54 kDa protein; Binds to the signal sequence of presecretory protein when they emerge from the ribosomes and transfers them to TRAM (translocating chain-associating membrane protein). Belongs to the GTP-binding SRP family. SRP54 subfamily.	0.629
OXA1L	SRPRA	ENSRROP00000014512	ENSRROP00000010167	OXA1L mitochondrial inner membrane protein.	SRP receptor subunit alpha.	0.604
SEC11A	SEC11C	ENSRROP00000030615	ENSRROP00000041328	Signal peptidase complex catalytic subunit SEC11.	Signal peptidase complex catalytic subunit SEC11.	0.901
SEC11A	SEC63	ENSRROP00000030615	ENSRROP00000023364	Signal peptidase complex catalytic subunit SEC11.	SEC63 homolog, protein translocation regulator.	0.430
SEC11A	SPCS1	ENSRROP00000030615	ENSRROP00000042851	Signal peptidase complex catalytic subunit SEC11.	Signal peptidase complex subunit 1.	0.951
SEC11A	SPCS3	ENSRROP00000030615	ENSRROP00000032398	Signal peptidase complex catalytic subunit SEC11.	Signal peptidase complex subunit 3.	0.954
SEC11C	SEC11A	ENSRROP00000041328	ENSRROP00000030615	Signal peptidase complex catalytic subunit SEC11.	Signal peptidase complex catalytic subunit SEC11.	0.901
SEC11C	SEC63	ENSRROP00000041328	ENSRROP00000023364	Signal peptidase complex catalytic subunit SEC11.	SEC63 homolog, protein translocation regulator.	0.430
SEC11C	SPCS1	ENSRROP00000041328	ENSRROP00000042851	Signal peptidase complex catalytic subunit SEC11.	Signal peptidase complex subunit 1.	0.951