STRINGSTRING
GSK3B GSK3B CAMK2D CAMK2D STAT5A STAT5A AKT1 AKT1 BRAF BRAF MAP2K7 MAP2K7 MAPK8 MAPK8 PAK2 PAK2 NCK2 NCK2 MAPK9 MAPK9 SHC4 SHC4 ERBB3 ERBB3 GAB1 GAB1 HBEGF HBEGF PIK3CA PIK3CA STAT5B STAT5B PIK3CD PIK3CD SOS1 SOS1 MAP2K2 MAP2K2 SHC1 SHC1 MYC MYC ABL1 ABL1 MAP2K4 MAP2K4 PRKCG PRKCG CAMK2A CAMK2A NRAS NRAS LOC104658196 LOC104658196 SRC SRC BAD BAD PRKCB PRKCB MAP2K1 MAP2K1 BTC BTC AKT3 AKT3 PIK3R1 PIK3R1 NRG3 NRG3 EGF EGF CRK CRK EREG EREG MAPK1 MAPK1 PLCG1 PLCG1 MTOR MTOR SOS2 SOS2 CDKN1B CDKN1B CDKN1A CDKN1A MAPK10 MAPK10 NRG1 NRG1 ERBB4 ERBB4 PIK3R3 PIK3R3 CBL CBL MAPK3 MAPK3 PTK2 PTK2 KRAS KRAS PAK4 PAK4 GRB2 GRB2 RPS6KB1 RPS6KB1 CAMK2B CAMK2B ELK1 ELK1 HRAS HRAS PAK6 PAK6 PAK5 PAK5 EGFR EGFR RAF1 RAF1 CAMK2G CAMK2G TGFA TGFA ARAF ARAF AREG AREG CRKL CRKL AKT2 AKT2 CBLB CBLB PRKCA PRKCA NCK1 NCK1 RPS6KB2 RPS6KB2 PIK3CB PIK3CB ERBB2 ERBB2 PLCG2 PLCG2 PAK1 PAK1 EIF4EBP1 EIF4EBP1 ABL2 ABL2
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
GSK3BGlycogen synthase kinase 3 beta; Belongs to the protein kinase superfamily. (309 aa)
CAMK2DCalcium/calmodulin dependent protein kinase II delta. (533 aa)
STAT5ASignal transducer and activator of transcription. (905 aa)
AKT1Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily. (480 aa)
BRAFB-Raf proto-oncogene, serine/threonine kinase. (761 aa)
MAP2K7Mitogen-activated protein kinase kinase 7. (403 aa)
MAPK8Mitogen-activated protein kinase. (427 aa)
PAK2Non-specific serine/threonine protein kinase. (524 aa)
NCK2Cytoplasmic protein. (382 aa)
MAPK9Mitogen-activated protein kinase. (387 aa)
SHC4SHC adaptor protein 4. (630 aa)
ERBB3Erb-b2 receptor tyrosine kinase 3. (1347 aa)
GAB1GRB2 associated binding protein 1. (724 aa)
HBEGFHeparin binding EGF like growth factor. (208 aa)
PIK3CAPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit. (1068 aa)
STAT5BSignal transducer and activator of transcription. (787 aa)
PIK3CDPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit. (1044 aa)
SOS1SOS Ras/Rac guanine nucleotide exchange factor 1. (1333 aa)
MAP2K2Mitogen-activated protein kinase kinase 2; Belongs to the protein kinase superfamily. (399 aa)
SHC1SHC adaptor protein 1. (574 aa)
MYCMyc proto-oncogene protein; Transcription factor that binds DNA in a non-specific manner, yet also specifically recognizes the core sequence 5'-CAC[GA]TG-3'. Activates the transcription of growth-related genes. (439 aa)
ABL1Tyrosine-protein kinase. (1149 aa)
MAP2K4Mitogen-activated protein kinase kinase 4; Belongs to the protein kinase superfamily. (410 aa)
PRKCGProtein kinase C; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. PKC subfamily. (697 aa)
CAMK2ACalcium/calmodulin dependent protein kinase II alpha; Belongs to the protein kinase superfamily. (489 aa)
NRASNRAS proto-oncogene, GTPase. (189 aa)
LOC104658196CRIB domain-containing protein. (176 aa)
SRCTyrosine-protein kinase. (540 aa)
BADBCL2 associated agonist of cell death. (167 aa)
PRKCBNon-specific serine/threonine protein kinase. (590 aa)
MAP2K1Mitogen-activated protein kinase kinase 1; Belongs to the protein kinase superfamily. (393 aa)
BTCBetacellulin. (178 aa)
AKT3Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily. (479 aa)
PIK3R1Phosphoinositide-3-kinase regulatory subunit 1. (724 aa)
NRG3Neuregulin 3. (402 aa)
EGFPro-epidermal growth factor; EGF stimulates the growth of various epidermal and epithelial tissues in vivo and in vitro and of some fibroblasts in cell culture. Magnesiotropic hormone that stimulates magnesium reabsorption in the renal distal convoluted tubule via engagement of EGFR and activation of the magnesium channel TRPM6. (1233 aa)
CRKCRK proto-oncogene, adaptor protein. (304 aa)
EREGEpiregulin. (163 aa)
MAPK1Mitogen-activated protein kinase. (330 aa)
PLCG11-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma; Mediates the production of the second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3). Plays an important role in the regulation of intracellular signaling cascades. (1303 aa)
MTORSerine/threonine-protein kinase mTOR; Belongs to the PI3/PI4-kinase family. (2549 aa)
SOS2SOS Ras/Rho guanine nucleotide exchange factor 2. (1332 aa)
CDKN1BCyclin dependent kinase inhibitor 1B. (198 aa)
CDKN1ACyclin dependent kinase inhibitor 1A. (164 aa)
MAPK10Mitogen-activated protein kinase. (550 aa)
NRG1Neuregulin 1. (713 aa)
ERBB4Receptor protein-tyrosine kinase. (1280 aa)
PIK3R3Phosphoinositide-3-kinase regulatory subunit 3. (461 aa)
CBLCbl proto-oncogene. (906 aa)
MAPK3Mitogen-activated protein kinase; Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. MAP kinase subfamily. (379 aa)
PTK2Protein tyrosine kinase 2; Belongs to the protein kinase superfamily. Tyr protein kinase family. (1109 aa)
KRASKRAS proto-oncogene, GTPase. (189 aa)
PAK4Non-specific serine/threonine protein kinase. (655 aa)
GRB2Growth factor receptor bound protein 2. (217 aa)
RPS6KB1Ribosomal protein S6 kinase; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. S6 kinase subfamily. (525 aa)
CAMK2BCalcium/calmodulin dependent protein kinase II beta. (653 aa)
ELK1Uncharacterized protein. (428 aa)
HRASHRas proto-oncogene, GTPase. (189 aa)
PAK6Non-specific serine/threonine protein kinase. (681 aa)
PAK5Non-specific serine/threonine protein kinase. (719 aa)
EGFRReceptor protein-tyrosine kinase. (1210 aa)
RAF1Uncharacterized protein. (668 aa)
CAMK2GCalcium/calmodulin dependent protein kinase II gamma. (559 aa)
TGFATransforming growth factor alpha. (166 aa)
ARAFA-Raf proto-oncogene, serine/threonine kinase. (606 aa)
AREGAmphiregulin. (274 aa)
CRKLCRK like proto-oncogene, adaptor protein. (303 aa)
AKT2Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily. (481 aa)
CBLBCbl proto-oncogene B. (982 aa)
PRKCAProtein kinase C; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. PKC subfamily. (672 aa)
NCK1Cytoplasmic protein. (377 aa)
RPS6KB2Ribosomal protein S6 kinase; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. S6 kinase subfamily. (485 aa)
PIK3CBPhosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit beta; Belongs to the PI3/PI4-kinase family. (1073 aa)
ERBB2Receptor protein-tyrosine kinase. (1352 aa)
PLCG21-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma; Mediates the production of the second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3). Plays an important role in the regulation of intracellular signaling cascades. (1265 aa)
PAK1Non-specific serine/threonine protein kinase. (555 aa)
EIF4EBP1Eukaryotic translation initiation factor 4E binding protein 1. (118 aa)
ABL2Tyrosine-protein kinase. (1164 aa)
Your Current Organism:
Rhinopithecus roxellana
NCBI taxonomy Id: 61622
Other names: Pygathrix roxellana, R. roxellana, golden snub-nosed monkey
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