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| | S1PR3 | Sphingosine-1-phosphate receptor 3; Belongs to the G-protein coupled receptor 1 family. (378 aa) |
| | S1PR1 | Sphingosine-1-phosphate receptor 1; Belongs to the G-protein coupled receptor 1 family. (382 aa) |
| | PLD1-2 | Uncharacterized protein. (57 aa) |
| | S1PR2 | Sphingosine-1-phosphate receptor 2; Belongs to the G-protein coupled receptor 1 family. (353 aa) |
| | AKT1 | Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily. (480 aa) |
| | CERS2 | Ceramide synthase 2. (423 aa) |
| | CERS5 | Ceramide synthase 5. (392 aa) |
| | PDPK1 | 3-phosphoinositide dependent protein kinase 1. (356 aa) |
| | ENSRROP00000003356 | Uncharacterized protein. (898 aa) |
| | CERS3 | Ceramide synthase 3. (385 aa) |
| | DEGS1 | Delta 4-desaturase, sphingolipid 1. (323 aa) |
| | RELA | RELA proto-oncogene, NF-kB subunit. (551 aa) |
| | MAPK8 | Mitogen-activated protein kinase. (427 aa) |
| | TNF | Tumor necrosis factor; Belongs to the tumor necrosis factor family. (233 aa) |
| | ACER1 | Alkaline ceramidase; Hydrolyzes the sphingolipid ceramide into sphingosine and free fatty acid. (264 aa) |
| | PPP2R5E | Serine/threonine-protein phosphatase 2A 56 kDa regulatory subunit; The B regulatory subunit might modulate substrate selectivity and catalytic activity, and also might direct the localization of the catalytic enzyme to a particular subcellular compartment. (467 aa) |
| | PPP2R5A | Serine/threonine-protein phosphatase 2A 56 kDa regulatory subunit; The B regulatory subunit might modulate substrate selectivity and catalytic activity, and also might direct the localization of the catalytic enzyme to a particular subcellular compartment. (486 aa) |
| | GNA13 | G protein subunit alpha 13. (308 aa) |
| | SGPP1 | Sphingosine-1-phosphate phosphatase 1. (441 aa) |
| | BAX | BCL2 associated X, apoptosis regulator. (197 aa) |
| | MAPK9 | Mitogen-activated protein kinase. (387 aa) |
| | PPP2R2D | Serine/threonine-protein phosphatase 2A 55 kDa regulatory subunit B; Belongs to the phosphatase 2A regulatory subunit B family. (451 aa) |
| | ADORA1 | Adenosine receptor A1; Receptor for adenosine. The activity of this receptor is mediated by G proteins which inhibit adenylyl cyclase. Belongs to the G-protein coupled receptor 1 family. (326 aa) |
| | TNFRSF1A | TNF receptor superfamily member 1A. (455 aa) |
| | PRKCE | Protein kinase C epsilon type; Calcium-independent, phospholipid- and diacylglycerol (DAG)- dependent serine/threonine-protein kinase that plays essential roles in the regulation of multiple cellular processes linked to cytoskeletal proteins, such as cell adhesion, motility, migration and cell cycle, functions in neuron growth and ion channel regulation, and is involved in immune response, cancer cell invasion and regulation of apoptosis. Mediates cell adhesion to the extracellular matrix via integrin- dependent signaling, by mediating angiotensin-2-induced activation of integrin beta- [...] (737 aa) |
| | GNAI2 | G protein subunit alpha i2. (355 aa) |
| | SGPL1 | Sphingosine-1-phosphate lyase 1. (568 aa) |
| | OPRD1 | Opioid receptor delta 1; Belongs to the G-protein coupled receptor 1 family. (372 aa) |
| | ASAH2 | Neutral ceramidase. (666 aa) |
| | ACER2 | Alkaline ceramidase; Hydrolyzes the sphingolipid ceramide into sphingosine and free fatty acid. (275 aa) |
| | PIK3CA | Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit. (1068 aa) |
| | SPTLC3 | Serine palmitoyltransferase long chain base subunit 3. (552 aa) |
| | PIK3CD | Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit. (1044 aa) |
| | MAP3K5 | Mitogen-activated protein kinase kinase kinase 5. (1374 aa) |
| | PTEN | Phosphatase and tensin homolog; Tumor suppressor. Acts as a dual-specificity protein phosphatase, dephosphorylating tyrosine-, serine- and threonine- phosphorylated proteins. Also acts as a lipid phosphatase. Belongs to the PTEN phosphatase protein family. (403 aa) |
| | MAP2K2 | Mitogen-activated protein kinase kinase 2; Belongs to the protein kinase superfamily. (399 aa) |
| | SPHK1 | Sphingosine kinase 1. (472 aa) |
| | RHOA | Ras homolog family member A. (193 aa) |
| | PRKCG | Protein kinase C; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. PKC subfamily. (697 aa) |
| | GNAI3 | G protein subunit alpha i3. (354 aa) |
| | TRAF2 | TNF receptor-associated factor; Belongs to the TNF receptor-associated factor family. (519 aa) |
| | KNG1 | Kininogen 1. (644 aa) |
| | NRAS | NRAS proto-oncogene, GTPase. (189 aa) |
| | FCER1A | Fc fragment of IgE receptor Ia. (260 aa) |
| | FYN | Tyrosine-protein kinase. (537 aa) |
| | PPP2R1B | Protein phosphatase 2 scaffold subunit Abeta. (667 aa) |
| | GNAI1 | G protein subunit alpha i1. (253 aa) |
| | PLCB3 | 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase; The production of the second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3) is mediated by activated phosphatidylinositol-specific phospholipase C enzymes. (1234 aa) |
| | PRKCB | Non-specific serine/threonine protein kinase. (590 aa) |
| | MAP2K1 | Mitogen-activated protein kinase kinase 1; Belongs to the protein kinase superfamily. (393 aa) |
| | NOS3 | Nitric oxide synthase; Produces nitric oxide (NO). (1205 aa) |
| | AKT3 | Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily. (479 aa) |
| | PIK3R1 | Phosphoinositide-3-kinase regulatory subunit 1. (724 aa) |
| | SPTLC1 | Serine palmitoyltransferase long chain base subunit 1. (473 aa) |
| | ROCK2 | Rho-associated protein kinase; Protein kinase which is a key regulator of actin cytoskeleton and cell polarity. (1383 aa) |
| | CTSD | Peptidase A1 domain-containing protein; Belongs to the peptidase A1 family. (594 aa) |
| | PLCB1 | 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase; The production of the second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3) is mediated by activated phosphatidylinositol-specific phospholipase C enzymes. (1114 aa) |
| | SPHK2 | Sphingosine kinase 2. (665 aa) |
| | ENSRROP00000024190 | Protein kinase domain-containing protein. (137 aa) |
| | DEGS2 | Delta 4-desaturase, sphingolipid 2. (323 aa) |
| | MAPK1 | Mitogen-activated protein kinase. (330 aa) |
| | PPP2CA | Serine/threonine-protein phosphatase. (309 aa) |
| | MAPK14 | Mitogen-activated protein kinase. (360 aa) |
| | PLCB4 | 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase; The production of the second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3) is mediated by activated phosphatidylinositol-specific phospholipase C enzymes. (1225 aa) |
| | TP53 | Cellular tumor antigen p53; Acts as a tumor suppressor in many tumor types; induces growth arrest or apoptosis depending on the physiological circumstances and cell type. Involved in cell cycle regulation as a trans-activator that acts to negatively regulate cell division by controlling a set of genes required for this process. One of the activated genes is an inhibitor of cyclin-dependent kinases. Apoptosis induction seems to be mediated either by stimulation of BAX and FAS antigen expression, or by repression of Bcl-2 expression; Belongs to the p53 family. (393 aa) |
| | SMPD2 | Sphingomyelin phosphodiesterase 2. (451 aa) |
| | GAB2 | GRB2 associated binding protein 2. (677 aa) |
| | MAPK10 | Mitogen-activated protein kinase. (550 aa) |
| | CERS1 | TLC domain-containing protein. (324 aa) |
| | SGMS2 | Sphingomyelin synthase 2. (365 aa) |
| | PPP2R1A | Protein phosphatase 2 scaffold subunit Aalpha. (589 aa) |
| | PIK3R3 | Phosphoinositide-3-kinase regulatory subunit 3. (461 aa) |
| | PPP2R3C | Protein phosphatase 2 regulatory subunit B''gamma. (453 aa) |
| | MAPK3 | Mitogen-activated protein kinase; Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. MAP kinase subfamily. (379 aa) |
| | KRAS | KRAS proto-oncogene, GTPase. (189 aa) |
| | BDKRB2 | Bradykinin receptor B2; Belongs to the G-protein coupled receptor 1 family. (391 aa) |
| | PPP2R2B | Serine/threonine-protein phosphatase 2A 55 kDa regulatory subunit B; Belongs to the phosphatase 2A regulatory subunit B family. (509 aa) |
| | ABCC1 | ATP binding cassette subfamily C member 1. (1531 aa) |
| | SMPD1 | Sphingomyelin phosphodiesterase; Converts sphingomyelin to ceramide. (644 aa) |
| | MS4A2 | Membrane spanning 4-domains A2. (245 aa) |
| | BCL2 | BCL2 apoptosis regulator. (239 aa) |
| | SPTLC2 | Serine palmitoyltransferase long chain base subunit 2. (560 aa) |
| | GNAQ | G protein subunit alpha q. (359 aa) |
| | HRAS | HRas proto-oncogene, GTPase. (189 aa) |
| | PPP2R5D | Serine/threonine-protein phosphatase 2A 56 kDa regulatory subunit; The B regulatory subunit might modulate substrate selectivity and catalytic activity, and also might direct the localization of the catalytic enzyme to a particular subcellular compartment. (605 aa) |
| | PPP2R2A | Serine/threonine-protein phosphatase 2A 55 kDa regulatory subunit B; Belongs to the phosphatase 2A regulatory subunit B family. (457 aa) |
| | RAF1 | Uncharacterized protein. (668 aa) |
| | NSMAF | Uncharacterized protein. (943 aa) |
| | PPP2R5B | Serine/threonine-protein phosphatase 2A 56 kDa regulatory subunit; The B regulatory subunit might modulate substrate selectivity and catalytic activity, and also might direct the localization of the catalytic enzyme to a particular subcellular compartment. (596 aa) |
| | PPP2R5C | Serine/threonine-protein phosphatase 2A 56 kDa regulatory subunit; The B regulatory subunit might modulate substrate selectivity and catalytic activity, and also might direct the localization of the catalytic enzyme to a particular subcellular compartment. (579 aa) |
| | PLD2 | Phospholipase. (933 aa) |
| | PPP2R3A | Protein phosphatase 2 regulatory subunit B''alpha. (1150 aa) |
| | PRKCZ | Protein kinase C; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. PKC subfamily. (582 aa) |
| | RAC2 | Rac family small GTPase 2. (192 aa) |
| | AKT2 | Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily. (481 aa) |
| | ROCK1 | Rho-associated protein kinase; Protein kinase which is a key regulator of actin cytoskeleton and cell polarity. (1368 aa) |
| | CERS6 | Ceramide synthase 6. (392 aa) |
| | FCER1G | Fc fragment of IgE receptor Ig. (112 aa) |
| | ASAH1 | N-acylsphingosine amidohydrolase 1; Belongs to the acid ceramidase family. (411 aa) |
| | PRKCA | Protein kinase C; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. PKC subfamily. (672 aa) |
| | GNA12 | G protein subunit alpha 12. (381 aa) |
| | PIK3CB | Phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit beta; Belongs to the PI3/PI4-kinase family. (1073 aa) |
| | PPP2R2C | Serine/threonine-protein phosphatase 2A 55 kDa regulatory subunit B; Belongs to the phosphatase 2A regulatory subunit B family. (447 aa) |
| | NFKB1 | Nuclear factor kappa B subunit 1. (975 aa) |
| | SGMS1 | Sphingomyelin synthase 1. (413 aa) |
