STRINGSTRING
UBOX5 UBOX5 LOC104677263 LOC104677263 UBE2G1 UBE2G1 UBE2L5 UBE2L5 VHL VHL LOC104681760 LOC104681760 LOC104657843 LOC104657843 SOCS1 SOCS1 LOC104657508 LOC104657508 UBE2O UBE2O ENSRROP00000002977 ENSRROP00000002977 ERCC8 ERCC8 NEDD4 NEDD4 SMURF2 SMURF2 UBE3C UBE3C PML PML UBE2M UBE2M CUL3 CUL3 ANAPC10 ANAPC10 TRIM32 TRIM32 LOC104665503 LOC104665503 SOCS3 SOCS3 CUL7 CUL7 LOC104674456 LOC104674456 TRIP12 TRIP12 UBE2L6 UBE2L6 RBX1 RBX1 PIAS1 PIAS1 UBA7 UBA7 PRKN PRKN UBE2G2 UBE2G2 COP1 COP1 UBE2E1 UBE2E1 RCHY1 RCHY1 HUWE1 HUWE1 UBE2E2 UBE2E2 CDC20 CDC20 CUL1 CUL1 UBE2QL1 UBE2QL1 BTRC BTRC CUL4B CUL4B WWP1 WWP1 ITCH ITCH UBE2K UBE2K ELOC ELOC CUL5 CUL5 NHLRC1 NHLRC1 SAE1 SAE1 UBA2 UBA2 ANAPC4 ANAPC4 PIAS4 PIAS4 UBE2Q2 UBE2Q2 CDC26 CDC26 UBE2D4 UBE2D4 ANAPC5 ANAPC5 FANCL FANCL UBC UBC SMURF1 SMURF1 LOC104677399 LOC104677399 UBA52 UBA52 UBA6 UBA6 CDC34 CDC34 AIRE AIRE CDC23 CDC23 KLHL13 KLHL13 ANAPC13 ANAPC13 UBA1 UBA1 ANAPC2 ANAPC2 UBA3 UBA3 MAP3K1 MAP3K1 XIAP XIAP SIAH1 SIAH1 PIAS3 PIAS3 UBE2R2 UBE2R2 FZR1 FZR1 UBE2Q1 UBE2Q1 LOC104678031 LOC104678031 RHOBTB2 RHOBTB2 CDC27 CDC27 RPS27A RPS27A RHOBTB1 RHOBTB1 UBE2D2 UBE2D2 FBXO2 FBXO2 UBE2N UBE2N UBE2U UBE2U PPIL2 PPIL2 UBE2H UBE2H SYVN1 SYVN1 CBL CBL UBE2D1 UBE2D1 BIRC7 BIRC7 KLHL9 KLHL9 UBE2E3 UBE2E3 BIRC2 BIRC2 UBE3A UBE3A LOC104673998 LOC104673998 SKP2 SKP2 CUL4A CUL4A BRCA1 BRCA1 UBR5 UBR5 KEAP1 KEAP1 BIRC6 BIRC6 HERC3 HERC3 WWP2 WWP2 UBE3B UBE3B DET1 DET1 DDB1 DDB1 PIAS2 PIAS2 TRAF6 TRAF6 TRIM37 TRIM37 UBE2F UBE2F CDC16 CDC16 CBLB CBLB HERC4 HERC4 UBE2I UBE2I UBE2A UBE2A SKP1 SKP1 ANAPC7 ANAPC7 UBE4A UBE4A UBE2J1 UBE2J1 FBXO4 FBXO4 CBLC CBLC UBE2S UBE2S HERC1 HERC1 FBXW7 FBXW7 NEDD4L NEDD4L
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
UBOX5U-box domain containing 5. (541 aa)
LOC104677263Uncharacterized protein; Belongs to the SKP1 family. (155 aa)
UBE2G1Ubiquitin conjugating enzyme E2 G1; Belongs to the ubiquitin-conjugating enzyme family. (170 aa)
UBE2L5Ubiquitin conjugating enzyme E2 L5; Belongs to the ubiquitin-conjugating enzyme family. (154 aa)
VHLVon Hippel-Lindau tumor suppressor. (213 aa)
LOC104681760UBIQUITIN_CONJUGAT_2 domain-containing protein; Belongs to the ubiquitin-conjugating enzyme family. (179 aa)
LOC104657843Ubiquitin conjugating enzyme E2 L3; Belongs to the ubiquitin-conjugating enzyme family. (154 aa)
SOCS1Suppressor of cytokine signaling 1. (215 aa)
LOC104657508UBIQUITIN_CONJUGAT_2 domain-containing protein; Belongs to the ubiquitin-conjugating enzyme family. (179 aa)
UBE2OUbiquitin conjugating enzyme E2 O. (1250 aa)
ENSRROP00000002977Uncharacterized protein. (245 aa)
ERCC8ERCC excision repair 8, CSA ubiquitin ligase complex subunit. (396 aa)
NEDD4NEDD4 E3 ubiquitin protein ligase. (1083 aa)
SMURF2E3 ubiquitin-protein ligase. (741 aa)
UBE3CUbiquitin protein ligase E3C. (1083 aa)
PMLPromyelocytic leukemia. (882 aa)
UBE2MUbiquitin conjugating enzyme E2 M; Belongs to the ubiquitin-conjugating enzyme family. (183 aa)
CUL3Cullin 3; Belongs to the cullin family. (767 aa)
ANAPC10Anaphase-promoting complex subunit 10; Component of the anaphase promoting complex/cyclosome (APC/C), a cell cycle-regulated E3 ubiquitin-protein ligase complex that controls progression through mitosis and the G1 phase of the cell cycle. (185 aa)
TRIM32Tripartite motif containing 32. (653 aa)
LOC104665503UBIQUITIN_CONJUGAT_2 domain-containing protein; Belongs to the ubiquitin-conjugating enzyme family. (152 aa)
SOCS3Suppressor of cytokine signaling 3. (225 aa)
CUL7Cullin 7; Belongs to the cullin family. (1728 aa)
LOC104674456Ubiquitin-like domain-containing protein. (118 aa)
TRIP12Thyroid hormone receptor interactor 12. (2038 aa)
UBE2L6Ubiquitin conjugating enzyme E2 L6; Belongs to the ubiquitin-conjugating enzyme family. (152 aa)
RBX1Ring-box 1. (108 aa)
PIAS1Protein inhibitor of activated STAT 1. (653 aa)
UBA7Ubiquitin like modifier activating enzyme 7; Belongs to the ubiquitin-activating E1 family. (1013 aa)
PRKNE3 ubiquitin-protein ligase parkin; Functions within a multiprotein E3 ubiquitin ligase complex, catalyzing the covalent attachment of ubiquitin moieties onto substrate proteins; Belongs to the RBR family. Parkin subfamily. (465 aa)
UBE2G2Ubiquitin conjugating enzyme E2 G2; Belongs to the ubiquitin-conjugating enzyme family. (165 aa)
COP1COP1 E3 ubiquitin ligase. (731 aa)
UBE2E1Ubiquitin conjugating enzyme E2 E1; Belongs to the ubiquitin-conjugating enzyme family. (193 aa)
RCHY1Ring finger and CHY zinc finger domain containing 1. (261 aa)
HUWE1HECT, UBA and WWE domain containing E3 ubiquitin protein ligase 1. (4423 aa)
UBE2E2Ubiquitin conjugating enzyme E2 E2; Belongs to the ubiquitin-conjugating enzyme family. (201 aa)
CDC20Cell division cycle 20. (499 aa)
CUL1Cullin 1; Belongs to the cullin family. (776 aa)
UBE2QL1Ubiquitin conjugating enzyme E2 Q family like 1. (161 aa)
BTRCBeta-transducin repeat containing E3 ubiquitin protein ligase. (605 aa)
CUL4BCullin 4B; Belongs to the cullin family. (913 aa)
WWP1E3 ubiquitin-protein ligase. (810 aa)
ITCHE3 ubiquitin-protein ligase. (862 aa)
UBE2KUbiquitin conjugating enzyme E2 K; Belongs to the ubiquitin-conjugating enzyme family. (200 aa)
ELOCSkp1_POZ domain-containing protein; Belongs to the SKP1 family. (112 aa)
CUL5Cullin 5; Belongs to the cullin family. (780 aa)
NHLRC1NHL repeat containing E3 ubiquitin protein ligase 1. (388 aa)
SAE1SUMO1 activating enzyme subunit 1. (346 aa)
UBA2SUMO-activating enzyme subunit 2; The heterodimer acts as an E1 ligase for SUMO1, SUMO2, SUMO3, and probably SUMO4. It mediates ATP-dependent activation of SUMO proteins followed by formation of a thioester bond between a SUMO protein and a conserved active site cysteine residue on UBA2/SAE2. Belongs to the ubiquitin-activating E1 family. (640 aa)
ANAPC4Anaphase-promoting complex subunit 4; Component of the anaphase promoting complex/cyclosome (APC/C), a cell cycle-regulated E3 ubiquitin ligase that controls progression through mitosis and the G1 phase of the cell cycle. Belongs to the APC4 family. (812 aa)
PIAS4Protein inhibitor of activated STAT 4. (529 aa)
UBE2Q2Ubiquitin conjugating enzyme E2 Q2. (375 aa)
CDC26Cell division cycle 26. (85 aa)
UBE2D4Ubiquitin conjugating enzyme E2 D4 (putative); Belongs to the ubiquitin-conjugating enzyme family. (173 aa)
ANAPC5Anaphase promoting complex subunit 5. (755 aa)
FANCLFA complementation group L. (383 aa)
UBCUncharacterized protein. (351 aa)
SMURF1E3 ubiquitin-protein ligase. (764 aa)
LOC104677399UBIQUITIN_CONJUGAT_2 domain-containing protein; Belongs to the ubiquitin-conjugating enzyme family. (149 aa)
UBA52Ubiquitin A-52 residue ribosomal protein fusion product 1. (232 aa)
UBA6Ubiquitin like modifier activating enzyme 6. (1052 aa)
CDC34Cell division cycle 34; Belongs to the ubiquitin-conjugating enzyme family. (236 aa)
AIREAutoimmune regulator. (547 aa)
CDC23Cell division cycle 23. (597 aa)
KLHL13Kelch like family member 13. (476 aa)
ANAPC13Anaphase promoting complex subunit 13. (74 aa)
UBA1Ubiquitin like modifier activating enzyme 1; Belongs to the ubiquitin-activating E1 family. (1143 aa)
ANAPC2Anaphase promoting complex subunit 2; Belongs to the cullin family. (822 aa)
UBA3Ubiquitin like modifier activating enzyme 3. (463 aa)
MAP3K1Mitogen-activated protein kinase kinase kinase 1. (1449 aa)
XIAPX-linked inhibitor of apoptosis. (497 aa)
SIAH1E3 ubiquitin-protein ligase; E3 ubiquitin-protein ligase that mediates ubiquitination and subsequent proteasomal degradation of target proteins. E3 ubiquitin ligases accept ubiquitin from an E2 ubiquitin-conjugating enzyme in the form of a thioester and then directly transfers the ubiquitin to targeted substrates. (313 aa)
PIAS3Protein inhibitor of activated STAT 3. (634 aa)
UBE2R2Ubiquitin conjugating enzyme E2 R2; Belongs to the ubiquitin-conjugating enzyme family. (238 aa)
FZR1Fizzy and cell division cycle 20 related 1. (546 aa)
UBE2Q1Ubiquitin conjugating enzyme E2 Q1. (253 aa)
LOC104678031UBIQUITIN_CONJUGAT_2 domain-containing protein; Belongs to the ubiquitin-conjugating enzyme family. (152 aa)
RHOBTB2Rho related BTB domain containing 2. (749 aa)
CDC27Uncharacterized protein. (294 aa)
RPS27AUbiquitin-like domain-containing protein. (156 aa)
RHOBTB1Rho related BTB domain containing 1. (696 aa)
UBE2D2Ubiquitin conjugating enzyme E2 D2; Belongs to the ubiquitin-conjugating enzyme family. (147 aa)
FBXO2F-box protein 2. (423 aa)
UBE2NUbiquitin conjugating enzyme E2 N; Belongs to the ubiquitin-conjugating enzyme family. (152 aa)
UBE2UUbiquitin conjugating enzyme E2 U; Belongs to the ubiquitin-conjugating enzyme family. (322 aa)
PPIL2Peptidylprolyl isomerase like 2. (520 aa)
UBE2HUbiquitin conjugating enzyme E2 H; Belongs to the ubiquitin-conjugating enzyme family. (183 aa)
SYVN1Synoviolin 1. (616 aa)
CBLCbl proto-oncogene. (906 aa)
UBE2D1Ubiquitin conjugating enzyme E2 D1; Belongs to the ubiquitin-conjugating enzyme family. (148 aa)
BIRC7Baculoviral IAP repeat containing 7. (298 aa)
KLHL9Kelch like family member 9. (612 aa)
UBE2E3Ubiquitin conjugating enzyme E2 E3; Belongs to the ubiquitin-conjugating enzyme family. (207 aa)
BIRC2Baculoviral IAP repeat containing 2. (618 aa)
UBE3AUbiquitin-protein ligase E3A; E3 ubiquitin-protein ligase which accepts ubiquitin from an E2 ubiquitin-conjugating enzyme in the form of a thioester and transfers it to its substrates. (877 aa)
LOC104673998UBIQUITIN_CONJUGAT_2 domain-containing protein; Belongs to the ubiquitin-conjugating enzyme family. (154 aa)
SKP2S-phase kinase associated protein 2. (424 aa)
CUL4ACullin 4A; Belongs to the cullin family. (659 aa)
BRCA1Breast cancer type 1 susceptibility protein homolog; E3 ubiquitin-protein ligase that specifically mediates the formation of 'Lys-6'-linked polyubiquitin chains and plays a central role in DNA repair by facilitating cellular responses to DNA damage. It is unclear whether it also mediates the formation of other types of polyubiquitin chains. The E3 ubiquitin-protein ligase activity is required for its tumor suppressor function. The BRCA1-BARD1 heterodimer coordinates a diverse range of cellular pathways such as DNA damage repair, ubiquitination and transcriptional regulation to maintain [...] (1836 aa)
UBR5Ubiquitin protein ligase E3 component n-recognin 5. (2794 aa)
KEAP1Kelch like ECH associated protein 1. (624 aa)
BIRC6Baculoviral IAP repeat containing 6. (4901 aa)
HERC3HECT domain-containing protein. (1050 aa)
WWP2E3 ubiquitin-protein ligase. (870 aa)
UBE3BUbiquitin protein ligase E3B. (1068 aa)
DET1Uncharacterized protein. (562 aa)
DDB1Damage specific DNA binding protein 1. (1147 aa)
PIAS2Protein inhibitor of activated STAT 2. (620 aa)
TRAF6TNF receptor-associated factor; Belongs to the TNF receptor-associated factor family. (522 aa)
TRIM37Tripartite motif containing 37. (963 aa)
UBE2FUBIQUITIN_CONJUGAT_2 domain-containing protein; Belongs to the ubiquitin-conjugating enzyme family. (185 aa)
CDC16Cell division cycle 16. (620 aa)
CBLBCbl proto-oncogene B. (982 aa)
HERC4HECT and RLD domain containing E3 ubiquitin protein ligase 4. (1057 aa)
UBE2IUbiquitin conjugating enzyme E2 I; Belongs to the ubiquitin-conjugating enzyme family. (231 aa)
UBE2AUbiquitin conjugating enzyme E2 A; Belongs to the ubiquitin-conjugating enzyme family. (152 aa)
SKP1S-phase kinase associated protein 1; Belongs to the SKP1 family. (163 aa)
ANAPC7Anaphase promoting complex subunit 7. (599 aa)
UBE4AUbiquitination factor E4A. (1081 aa)
UBE2J1Ubiquitin conjugating enzyme E2 J1. (318 aa)
FBXO4F-box protein 4. (387 aa)
CBLCCbl proto-oncogene C. (527 aa)
UBE2SUbiquitin conjugating enzyme E2 S; Belongs to the ubiquitin-conjugating enzyme family. (222 aa)
HERC1HECT and RLD domain containing E3 ubiquitin protein ligase family member 1. (4861 aa)
FBXW7F-box and WD repeat domain containing 7. (707 aa)
NEDD4LNEDD4 like E3 ubiquitin protein ligase. (1255 aa)
Your Current Organism:
Rhinopithecus roxellana
NCBI taxonomy Id: 61622
Other names: Pygathrix roxellana, R. roxellana, golden snub-nosed monkey
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