58 items (Rhinopithecus roxellana) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	GABARAP	GABA type A receptor-associated protein. (117 aa)
	HIF1A	Hypoxia inducible factor 1 subunit alpha. (826 aa)
	ATG9A	Autophagy-related protein 9; Involved in autophagy and cytoplasm to vacuole transport (Cvt) vesicle formation. Plays a key role in the organization of the preautophagosomal structure/phagophore assembly site (PAS), the nucleating site for formation of the sequestering vesicle. Belongs to the ATG9 family. (852 aa)
	RHOT2	Mitochondrial Rho GTPase; Mitochondrial GTPase involved in mitochondrial trafficking. Belongs to the mitochondrial Rho GTPase family. (618 aa)
	TBC1D15	TBC1 domain family member 15. (691 aa)
	MFN1	Mitofusin 1; Belongs to the TRAFAC class dynamin-like GTPase superfamily. Dynamin/Fzo/YdjA family. (741 aa)
	RAB7B	RAB7B, member RAS oncogene family. (199 aa)
	RELA	RELA proto-oncogene, NF-kB subunit. (551 aa)
	MAPK8	Mitogen-activated protein kinase. (427 aa)
	FUNDC1	Uncharacterized protein. (155 aa)
	RRAS	RAS related. (218 aa)
	FIS1	Mitochondrial fission 1 protein; Involved in the fragmentation of the mitochondrial network and its perinuclear clustering. (152 aa)
	ATF4	Activating transcription factor 4. (351 aa)
	MAPK9	Mitogen-activated protein kinase. (387 aa)
	FOXO3	Forkhead box O3. (617 aa)
	PRKN	E3 ubiquitin-protein ligase parkin; Functions within a multiprotein E3 ubiquitin ligase complex, catalyzing the covalent attachment of ubiquitin moieties onto substrate proteins; Belongs to the RBR family. Parkin subfamily. (465 aa)
	MRAS	Muscle RAS oncogene homolog. (208 aa)
	SP1	Sp1 transcription factor. (786 aa)
	MITF	Melanocyte inducing transcription factor. (526 aa)
	TFE3	Transcription factor binding to IGHM enhancer 3. (575 aa)
	BNIP3L	BCL2 interacting protein 3 like. (218 aa)
	USP8	Ubiquitin specific peptidase 8; Belongs to the peptidase C19 family. (1118 aa)
	RAB7A	RAB7A, member RAS oncogene family. (207 aa)
	BCL2L13	BCL2 like 13. (485 aa)
	NRAS	NRAS proto-oncogene, GTPase. (189 aa)
	UBC	Uncharacterized protein. (351 aa)
	UBA52	Ubiquitin A-52 residue ribosomal protein fusion product 1. (232 aa)
	SRC	Tyrosine-protein kinase. (540 aa)
	NBR1	NBR1 autophagy cargo receptor. (986 aa)
	AMBRA1	Autophagy and beclin 1 regulator 1. (1298 aa)
	BNIP3	BCL2 interacting protein 3. (194 aa)
	PGAM5	PGAM family member 5, mitochondrial serine/threonine protein phosphatase. (260 aa)
	SQSTM1	Sequestosome 1. (451 aa)
	GABARAPL1	GABA type A receptor associated protein like 1. (146 aa)
	TP53	Cellular tumor antigen p53; Acts as a tumor suppressor in many tumor types; induces growth arrest or apoptosis depending on the physiological circumstances and cell type. Involved in cell cycle regulation as a trans-activator that acts to negatively regulate cell division by controlling a set of genes required for this process. One of the activated genes is an inhibitor of cyclin-dependent kinases. Apoptosis induction seems to be mediated either by stimulation of BAX and FAS antigen expression, or by repression of Bcl-2 expression; Belongs to the p53 family. (393 aa)
	USP15	Ubiquitin carboxyl-terminal hydrolase; Deubiquitinating enzyme that removes conjugated ubiquitin from specific proteins to regulate different cellular processes. Belongs to the peptidase C19 family. (981 aa)
	RPS27A	Ubiquitin-like domain-containing protein. (156 aa)
	BCL2L1	BCL2 like 1. (233 aa)
	BECN1	Beclin 1. (450 aa)
	MAPK10	Mitogen-activated protein kinase. (550 aa)
	EIF2AK3	Eukaryotic translation initiation factor 2 alpha kinase 3. (1115 aa)
	E2F1	E2F transcription factor 1. (485 aa)
	PINK1	PTEN induced kinase 1. (581 aa)
	CITED2	Cbp/p300 interacting transactivator with Glu/Asp rich carboxy-terminal domain 2. (275 aa)
	TAX1BP1	Tax1 binding protein 1. (813 aa)
	KRAS	KRAS proto-oncogene, GTPase. (189 aa)
	RHOT1	Mitochondrial Rho GTPase; Mitochondrial GTPase involved in mitochondrial trafficking. Belongs to the mitochondrial Rho GTPase family. (709 aa)
	HRAS	HRas proto-oncogene, GTPase. (189 aa)
	TFEB	Transcription factor EB. (490 aa)
	TBC1D17	TBC1 domain family member 17. (649 aa)
	CSNK2A1	Protein kinase domain-containing protein; Belongs to the protein kinase superfamily. (391 aa)
	ATG5	Autophagy protein 5; Involved in autophagic vesicle formation. (275 aa)
	OPTN	Optineurin. (570 aa)
	TBK1	TANK binding kinase 1. (729 aa)
	ATG9B	Autophagy-related protein 9; Involved in autophagy and cytoplasm to vacuole transport (Cvt) vesicle formation. Plays a key role in the organization of the preautophagosomal structure/phagophore assembly site (PAS), the nucleating site for formation of the sequestering vesicle. Belongs to the ATG9 family. (922 aa)
	RRAS2	RAS related 2. (176 aa)
	GABARAPL2	GABA type A receptor associated protein like 2. (117 aa)
	CSNK2B	Uncharacterized protein. (298 aa)

Your Current Organism:

Rhinopithecus roxellana

NCBI taxonomy Id: 61622
Other names: Pygathrix roxellana, R. roxellana, golden snub-nosed monkey

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
AMBRA1	ATG5	ENSRROP00000021502	ENSRROP00000038546	Autophagy and beclin 1 regulator 1.	Autophagy protein 5; Involved in autophagic vesicle formation.	0.572
AMBRA1	ATG9A	ENSRROP00000021502	ENSRROP00000000867	Autophagy and beclin 1 regulator 1.	Autophagy-related protein 9; Involved in autophagy and cytoplasm to vacuole transport (Cvt) vesicle formation. Plays a key role in the organization of the preautophagosomal structure/phagophore assembly site (PAS), the nucleating site for formation of the sequestering vesicle. Belongs to the ATG9 family.	0.496
AMBRA1	BCL2L13	ENSRROP00000021502	ENSRROP00000016836	Autophagy and beclin 1 regulator 1.	BCL2 like 13.	0.565
AMBRA1	BECN1	ENSRROP00000021502	ENSRROP00000027668	Autophagy and beclin 1 regulator 1.	Beclin 1.	0.978
AMBRA1	PRKN	ENSRROP00000021502	ENSRROP00000010084	Autophagy and beclin 1 regulator 1.	E3 ubiquitin-protein ligase parkin; Functions within a multiprotein E3 ubiquitin ligase complex, catalyzing the covalent attachment of ubiquitin moieties onto substrate proteins; Belongs to the RBR family. Parkin subfamily.	0.956
ATF4	EIF2AK3	ENSRROP00000007388	ENSRROP00000030535	Activating transcription factor 4.	Eukaryotic translation initiation factor 2 alpha kinase 3.	0.969
ATF4	PINK1	ENSRROP00000007388	ENSRROP00000031444	Activating transcription factor 4.	PTEN induced kinase 1.	0.413
ATG5	AMBRA1	ENSRROP00000038546	ENSRROP00000021502	Autophagy protein 5; Involved in autophagic vesicle formation.	Autophagy and beclin 1 regulator 1.	0.572
ATG5	ATG9A	ENSRROP00000038546	ENSRROP00000000867	Autophagy protein 5; Involved in autophagic vesicle formation.	Autophagy-related protein 9; Involved in autophagy and cytoplasm to vacuole transport (Cvt) vesicle formation. Plays a key role in the organization of the preautophagosomal structure/phagophore assembly site (PAS), the nucleating site for formation of the sequestering vesicle. Belongs to the ATG9 family.	0.756
ATG5	ATG9B	ENSRROP00000038546	ENSRROP00000040295	Autophagy protein 5; Involved in autophagic vesicle formation.	Autophagy-related protein 9; Involved in autophagy and cytoplasm to vacuole transport (Cvt) vesicle formation. Plays a key role in the organization of the preautophagosomal structure/phagophore assembly site (PAS), the nucleating site for formation of the sequestering vesicle. Belongs to the ATG9 family.	0.599
ATG5	BCL2L1	ENSRROP00000038546	ENSRROP00000027448	Autophagy protein 5; Involved in autophagic vesicle formation.	BCL2 like 1.	0.743
ATG5	BECN1	ENSRROP00000038546	ENSRROP00000027668	Autophagy protein 5; Involved in autophagic vesicle formation.	Beclin 1.	0.702
ATG5	BNIP3	ENSRROP00000038546	ENSRROP00000021586	Autophagy protein 5; Involved in autophagic vesicle formation.	BCL2 interacting protein 3.	0.589
ATG5	BNIP3L	ENSRROP00000038546	ENSRROP00000015080	Autophagy protein 5; Involved in autophagic vesicle formation.	BCL2 interacting protein 3 like.	0.459
ATG5	FIS1	ENSRROP00000038546	ENSRROP00000005120	Autophagy protein 5; Involved in autophagic vesicle formation.	Mitochondrial fission 1 protein; Involved in the fragmentation of the mitochondrial network and its perinuclear clustering.	0.408
ATG5	FUNDC1	ENSRROP00000038546	ENSRROP00000004546	Autophagy protein 5; Involved in autophagic vesicle formation.	Uncharacterized protein.	0.501
ATG5	GABARAP	ENSRROP00000038546	ENSRROP00000000436	Autophagy protein 5; Involved in autophagic vesicle formation.	GABA type A receptor-associated protein.	0.975
ATG5	GABARAPL1	ENSRROP00000038546	ENSRROP00000025249	Autophagy protein 5; Involved in autophagic vesicle formation.	GABA type A receptor associated protein like 1.	0.975
ATG5	GABARAPL2	ENSRROP00000038546	ENSRROP00000042155	Autophagy protein 5; Involved in autophagic vesicle formation.	GABA type A receptor associated protein like 2.	0.989
ATG5	MFN1	ENSRROP00000038546	ENSRROP00000003762	Autophagy protein 5; Involved in autophagic vesicle formation.	Mitofusin 1; Belongs to the TRAFAC class dynamin-like GTPase superfamily. Dynamin/Fzo/YdjA family.	0.743