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SEC61G SEC61G LOC104677263 LOC104677263 RPN1 RPN1 UBE2G1 UBE2G1 MAN1A2 MAN1A2 HSPA1L HSPA1L BAK1 BAK1 CAPN2 CAPN2 MOGS MOGS TRAM1L1 TRAM1L1 UBQLN2 UBQLN2 MAP2K7 MAP2K7 ATF6B ATF6B NPLOC4 NPLOC4 DNAJC1 DNAJC1 ERN1 ERN1 MAPK8 MAPK8 STT3B STT3B EIF2AK4 EIF2AK4 EIF2AK1 EIF2AK1 DDIT3 DDIT3 BAX BAX ATF4 ATF4 MAPK9 MAPK9 P4HB P4HB HSPA8-2 HSPA8-2 ATF6 ATF6 HSPA6 HSPA6 RRBP1 RRBP1 HSPA5 HSPA5 CRYAB CRYAB SAR1B SAR1B DNAJB2 DNAJB2 RBX1 RBX1 DNAJC5B DNAJC5B PRKN PRKN UBE2G2 UBE2G2 MAN1A1 MAN1A1 DNAJA1 DNAJA1 CUL1 CUL1 WFS1 WFS1 TUSC3 TUSC3 EIF2S1 EIF2S1 DNAJC3 DNAJC3 DNAJC10 DNAJC10 EDEM3 EDEM3 CKAP4 CKAP4 UBXN6 UBXN6 DNAJB12 DNAJB12 UGGT1 UGGT1 UBXN4 UBXN4 MAP3K5 MAP3K5 BAG1 BAG1 RNF185 RNF185 DAD1 DAD1 HSPH1 HSPH1 LOC104677995 LOC104677995 TXNDC5 TXNDC5 TRAF2 TRAF2 UBE2D4 UBE2D4 EDEM2 EDEM2 SVIP SVIP VCP VCP MAN1C1 MAN1C1 DNAJC5G DNAJC5G LOC104677399 LOC104677399 SEC24C SEC24C CANX CANX SEC24D SEC24D DDOST DDOST UBQLN1 UBQLN1 PDIA3 PDIA3 XBP1 XBP1 ERO1B ERO1B NGLY1 NGLY1 SEC63 SEC63 DNAJB1 DNAJB1 SSR4 SSR4 SEC24B SEC24B HYOU1 HYOU1 LMAN1 LMAN1 UBXN2A UBXN2A SEC31B SEC31B SIL1 SIL1 UBXN8 UBXN8 PLAA PLAA GANAB GANAB SSR3 SSR3 PREB PREB CHEK1 CHEK1 SSR2 SSR2 DNAJB11 DNAJB11 MAPK10 MAPK10 UBE2D2 UBE2D2 UFD1 UFD1 FBXO2 FBXO2 SEL1L SEL1L RNF5 RNF5 LMAN2 LMAN2 NSFL1C NSFL1C EIF2AK3 EIF2AK3 SYVN1 SYVN1 HSPBP1 HSPBP1 PRKCSH PRKCSH UBE2D1 UBE2D1 UGGT2 UGGT2 SELENOS SELENOS RPN2 RPN2 EIF2AK2 EIF2AK2 RAD23A RAD23A PDIA6 PDIA6 SEC62 SEC62 SEC13 SEC13 SEC61B SEC61B UBXN1 UBXN1 BCL2 BCL2 MBTPS1 MBTPS1 DNAJA2 DNAJA2 HSP90B1 HSP90B1 LMAN1L LMAN1L CAPN1 CAPN1 DERL2 DERL2 FBXO6 FBXO6 ERLEC1 ERLEC1 LOC104659481 LOC104659481 ERO1A ERO1A ERP29 ERP29 PPP1R15A PPP1R15A YOD1 YOD1 SEC31A SEC31A HSPA4L HSPA4L DERL1 DERL1 RAD23B RAD23B PDIA4 PDIA4 SAR1A SAR1A SEC61A1 SEC61A1 SKP1 SKP1 EDEM1 EDEM1 SEC23B SEC23B MAN1B1 MAN1B1 CALR CALR DNAJC5 DNAJC5 UBE2J1 UBE2J1 HSP90AB1 HSP90AB1 AMFR AMFR BAG2 BAG2 NFE2L2 NFE2L2 LOC104666118 LOC104666118 SEC24A SEC24A BCAP31 BCAP31 MARCHF6 MARCHF6
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query proteins and first shell of interactors
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second shell of interactors
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proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
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textmining
co-expression
protein homology
Your Input:
SEC61GSEC61 translocon gamma subunit. (68 aa)
LOC104677263Uncharacterized protein; Belongs to the SKP1 family. (155 aa)
RPN1Dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit 1; Subunit of the oligosaccharyl transferase (OST) complex that catalyzes the initial transfer of a defined glycan (Glc(3)Man(9)GlcNAc(2) in eukaryotes) from the lipid carrier dolichol- pyrophosphate to an asparagine residue within an Asn-X-Ser/Thr consensus motif in nascent polypeptide chains, the first step in protein N-glycosylation. N-glycosylation occurs cotranslationally and the complex associates with the Sec61 complex at the channel-forming translocon complex that mediates protein translocation across the en [...] (607 aa)
UBE2G1Ubiquitin conjugating enzyme E2 G1; Belongs to the ubiquitin-conjugating enzyme family. (170 aa)
MAN1A2alpha-1,2-Mannosidase; Belongs to the glycosyl hydrolase 47 family. (641 aa)
HSPA1LHeat shock protein family A (Hsp70) member 1 like; Belongs to the heat shock protein 70 family. (641 aa)
BAK1BCL2 antagonist/killer 1. (211 aa)
CAPN2Calpain 2; Belongs to the peptidase C2 family. (597 aa)
MOGSMannosyl-oligosaccharide glucosidase. (837 aa)
TRAM1L1Translocating chain-associated membrane protein; Belongs to the TRAM family. (369 aa)
UBQLN2Ubiquilin 2. (624 aa)
MAP2K7Mitogen-activated protein kinase kinase 7. (403 aa)
ATF6BActivating transcription factor 6 beta. (708 aa)
NPLOC4NPL4 homolog, ubiquitin recognition factor. (616 aa)
DNAJC1DnaJ heat shock protein family (Hsp40) member C1. (556 aa)
ERN1Endoplasmic reticulum to nucleus signaling 1. (980 aa)
MAPK8Mitogen-activated protein kinase. (427 aa)
STT3BSTT3 oligosaccharyltransferase complex catalytic subunit B. (822 aa)
EIF2AK4Eukaryotic translation initiation factor 2 alpha kinase 4. (1649 aa)
EIF2AK1Eukaryotic translation initiation factor 2 alpha kinase 1. (631 aa)
DDIT3DNA damage-inducible transcript 3 protein; Multifunctional transcription factor in ER stress response. Plays an essential role in the response to a wide variety of cell stresses and induces cell cycle arrest and apoptosis in response to ER stress. Plays a dual role both as an inhibitor of CCAAT/enhancer- binding protein (C/EBP) function and as an activator of other genes. Acts as a dominant-negative regulator of C/EBP-induced transcription: dimerizes with members of the C/EBP family, impairs their association with C/EBP binding sites in the promoter regions, and inhibits the expression [...] (169 aa)
BAXBCL2 associated X, apoptosis regulator. (197 aa)
ATF4Activating transcription factor 4. (351 aa)
MAPK9Mitogen-activated protein kinase. (387 aa)
P4HBProtein disulfide-isomerase. (510 aa)
HSPA8-2Uncharacterized protein. (129 aa)
ATF6Activating transcription factor 6. (669 aa)
HSPA6Heat shock protein family A (Hsp70) member 6; Belongs to the heat shock protein 70 family. (608 aa)
RRBP1Ribosome binding protein 1. (1440 aa)
HSPA5Heat shock protein family A (Hsp70) member 5; Belongs to the heat shock protein 70 family. (654 aa)
CRYABCrystallin alpha B; May contribute to the transparency and refractive index of the lens. Has chaperone-like activity, preventing aggregation of various proteins under a wide range of stress conditions. (175 aa)
SAR1BSecretion associated Ras related GTPase 1B; Belongs to the small GTPase superfamily. SAR1 family. (198 aa)
DNAJB2DnaJ heat shock protein family (Hsp40) member B2. (324 aa)
RBX1Ring-box 1. (108 aa)
DNAJC5BDnaJ heat shock protein family (Hsp40) member C5 beta. (201 aa)
PRKNE3 ubiquitin-protein ligase parkin; Functions within a multiprotein E3 ubiquitin ligase complex, catalyzing the covalent attachment of ubiquitin moieties onto substrate proteins; Belongs to the RBR family. Parkin subfamily. (465 aa)
UBE2G2Ubiquitin conjugating enzyme E2 G2; Belongs to the ubiquitin-conjugating enzyme family. (165 aa)
MAN1A1alpha-1,2-Mannosidase; Belongs to the glycosyl hydrolase 47 family. (737 aa)
DNAJA1Uncharacterized protein. (397 aa)
CUL1Cullin 1; Belongs to the cullin family. (776 aa)
WFS1Wolframin ER transmembrane glycoprotein. (890 aa)
TUSC3Tumor suppressor candidate 3. (348 aa)
EIF2S1Eukaryotic translation initiation factor 2 subunit alpha. (295 aa)
DNAJC3DnaJ heat shock protein family (Hsp40) member C3. (504 aa)
DNAJC10DnaJ heat shock protein family (Hsp40) member C10. (822 aa)
EDEM3alpha-1,2-Mannosidase; Belongs to the glycosyl hydrolase 47 family. (936 aa)
CKAP4Cytoskeleton associated protein 4. (597 aa)
UBXN6UBX domain protein 6. (441 aa)
DNAJB12DnaJ heat shock protein family (Hsp40) member B12. (411 aa)
UGGT1UDP-glucose glycoprotein glucosyltransferase 1. (1544 aa)
UBXN4UBX domain protein 4. (508 aa)
MAP3K5Mitogen-activated protein kinase kinase kinase 5. (1374 aa)
BAG1BCL2 associated athanogene 1. (340 aa)
RNF185Ring finger protein 185. (192 aa)
DAD1Dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit DAD1; Subunit of the oligosaccharyl transferase (OST) complex that catalyzes the initial transfer of a defined glycan (Glc(3)Man(9)GlcNAc(2) in eukaryotes) from the lipid carrier dolichol- pyrophosphate to an asparagine residue within an Asn-X-Ser/Thr consensus motif in nascent polypeptide chains, the first step in protein N-glycosylation. N-glycosylation occurs cotranslationally and the complex associates with the Sec61 complex at the channel-forming translocon complex that mediates protein translocation across the [...] (113 aa)
HSPH1Heat shock protein family H (Hsp110) member 1. (858 aa)
LOC104677995SHSP domain-containing protein; May contribute to the transparency and refractive index of the lens. Has chaperone-like activity, preventing aggregation of various proteins under a wide range of stress conditions. (172 aa)
TXNDC5Thioredoxin domain containing 5; Belongs to the protein disulfide isomerase family. (324 aa)
TRAF2TNF receptor-associated factor; Belongs to the TNF receptor-associated factor family. (519 aa)
UBE2D4Ubiquitin conjugating enzyme E2 D4 (putative); Belongs to the ubiquitin-conjugating enzyme family. (173 aa)
EDEM2alpha-1,2-Mannosidase; Belongs to the glycosyl hydrolase 47 family. (578 aa)
SVIPSmall VCP interacting protein. (106 aa)
VCPValosin containing protein. (754 aa)
MAN1C1alpha-1,2-Mannosidase; Belongs to the glycosyl hydrolase 47 family. (630 aa)
DNAJC5GDnaJ heat shock protein family (Hsp40) member C5 gamma. (189 aa)
LOC104677399UBIQUITIN_CONJUGAT_2 domain-containing protein; Belongs to the ubiquitin-conjugating enzyme family. (149 aa)
SEC24CSEC24 homolog C, COPII coat complex component. (1117 aa)
CANXCalnexin. (600 aa)
SEC24DSEC24 homolog D, COPII coat complex component. (1032 aa)
DDOSTDolichyl-diphosphooligosaccharide--protein glycosyltransferase 48 kDa subunit; Subunit of the oligosaccharyl transferase (OST) complex that catalyzes the initial transfer of a defined glycan (Glc(3)Man(9)GlcNAc(2) in eukaryotes) from the lipid carrier dolichol- pyrophosphate to an asparagine residue within an Asn-X-Ser/Thr consensus motif in nascent polypeptide chains, the first step in protein N-glycosylation. N-glycosylation occurs cotranslationally and the complex associates with the Sec61 complex at the channel-forming translocon complex that mediates protein translocation across t [...] (445 aa)
UBQLN1Ubiquilin 1. (589 aa)
PDIA3Protein disulfide-isomerase. (505 aa)
XBP1BZIP domain-containing protein. (380 aa)
ERO1BEndoplasmic reticulum oxidoreductase 1 beta. (468 aa)
NGLY1N-glycanase 1. (654 aa)
SEC63SEC63 homolog, protein translocation regulator. (760 aa)
DNAJB1DnaJ heat shock protein family (Hsp40) member B1. (340 aa)
SSR4Signal sequence receptor subunit 4. (173 aa)
SEC24BSEC24 homolog B, COPII coat complex component. (690 aa)
HYOU1Hypoxia up-regulated 1. (1011 aa)
LMAN1Lectin, mannose binding 1. (510 aa)
UBXN2AUBX domain protein 2A. (260 aa)
SEC31BSEC31 homolog B, COPII coat complex component. (1178 aa)
SIL1SIL1 nucleotide exchange factor. (468 aa)
UBXN8UBX domain protein 8. (269 aa)
PLAAPhospholipase A2 activating protein. (795 aa)
GANABGlucosidase II alpha subunit; Belongs to the glycosyl hydrolase 31 family. (972 aa)
SSR3Signal sequence receptor subunit 3. (185 aa)
PREBWD_REPEATS_REGION domain-containing protein. (417 aa)
CHEK1Uncharacterized protein. (766 aa)
SSR2Translocon-associated protein subunit beta; TRAP proteins are part of a complex whose function is to bind calcium to the ER membrane and thereby regulate the retention of ER resident proteins. (196 aa)
DNAJB11J domain-containing protein. (358 aa)
MAPK10Mitogen-activated protein kinase. (550 aa)
UBE2D2Ubiquitin conjugating enzyme E2 D2; Belongs to the ubiquitin-conjugating enzyme family. (147 aa)
UFD1Uncharacterized protein. (354 aa)
FBXO2F-box protein 2. (423 aa)
SEL1LSEL1L adaptor subunit of ERAD E3 ubiquitin ligase. (794 aa)
RNF5Ring finger protein 5. (180 aa)
LMAN2Lectin, mannose binding 2. (356 aa)
NSFL1CNSFL1 cofactor. (372 aa)
EIF2AK3Eukaryotic translation initiation factor 2 alpha kinase 3. (1115 aa)
SYVN1Synoviolin 1. (616 aa)
HSPBP1HSPA (Hsp70) binding protein 1. (361 aa)
PRKCSHProtein kinase C substrate 80K-H. (534 aa)
UBE2D1Ubiquitin conjugating enzyme E2 D1; Belongs to the ubiquitin-conjugating enzyme family. (148 aa)
UGGT2UDP-glucose glycoprotein glucosyltransferase 2. (1516 aa)
SELENOSSelenoprotein S. (210 aa)
RPN2Dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit 2; Subunit of the oligosaccharyl transferase (OST) complex that catalyzes the initial transfer of a defined glycan (Glc(3)Man(9)GlcNAc(2) in eukaryotes) from the lipid carrier dolichol- pyrophosphate to an asparagine residue within an Asn-X-Ser/Thr consensus motif in nascent polypeptide chains, the first step in protein N-glycosylation. N-glycosylation occurs cotranslationally and the complex associates with the Sec61 complex at the channel-forming translocon complex that mediates protein translocation across the en [...] (647 aa)
EIF2AK2Eukaryotic translation initiation factor 2 alpha kinase 2. (550 aa)
RAD23ARAD23 homolog A, nucleotide excision repair protein. (369 aa)
PDIA6Protein disulfide isomerase family A member 6; Belongs to the protein disulfide isomerase family. (512 aa)
SEC62SEC62 homolog, preprotein translocation factor. (399 aa)
SEC13SEC13 homolog, nuclear pore and COPII coat complex component; Belongs to the WD repeat SEC13 family. (331 aa)
SEC61BProtein transport protein Sec61 subunit beta; Necessary for protein translocation in the endoplasmic reticulum. (96 aa)
UBXN1UBX domain protein 1. (310 aa)
BCL2BCL2 apoptosis regulator. (239 aa)
MBTPS1Membrane bound transcription factor peptidase, site 1. (1052 aa)
DNAJA2DnaJ heat shock protein family (Hsp40) member A2. (412 aa)
HSP90B1Heat shock protein 90 beta family member 1. (804 aa)
LMAN1LLectin, mannose binding 1 like. (508 aa)
CAPN1Calpain 1; Belongs to the peptidase C2 family. (714 aa)
DERL2Derlin; Functional component of endoplasmic reticulum-associated degradation (ERAD) for misfolded lumenal proteins. May act by forming a channel that allows the retrotranslocation of misfolded proteins into the cytosol where they are ubiquitinated and degraded by the proteasome; Belongs to the derlin family. (239 aa)
FBXO6F-box protein 6. (293 aa)
ERLEC1Endoplasmic reticulum lectin 1. (483 aa)
LOC104659481Uncharacterized protein. (202 aa)
ERO1AEndoplasmic reticulum oxidoreductase 1 alpha. (468 aa)
ERP29Endoplasmic reticulum resident protein 29; Does not seem to be a disulfide isomerase. (261 aa)
PPP1R15AProtein phosphatase 1 regulatory subunit 15A. (692 aa)
YOD1YOD1 deubiquitinase. (348 aa)
SEC31ASEC31 homolog A, COPII coat complex component. (1251 aa)
HSPA4LHeat shock protein family A (Hsp70) member 4 like. (840 aa)
DERL1Derlin; Functional component of endoplasmic reticulum-associated degradation (ERAD) for misfolded lumenal proteins. May act by forming a channel that allows the retrotranslocation of misfolded proteins into the cytosol where they are ubiquitinated and degraded by the proteasome; Belongs to the derlin family. (251 aa)
RAD23BRAD23 homolog B, nucleotide excision repair protein. (409 aa)
PDIA4Protein disulfide-isomerase A4. (643 aa)
SAR1AUncharacterized protein; Belongs to the small GTPase superfamily. SAR1 family. (198 aa)
SEC61A1Plug_translocon domain-containing protein. (482 aa)
SKP1S-phase kinase associated protein 1; Belongs to the SKP1 family. (163 aa)
EDEM1alpha-1,2-Mannosidase; Belongs to the glycosyl hydrolase 47 family. (657 aa)
SEC23BProtein transport protein SEC23; Component of the coat protein complex II (COPII) which promotes the formation of transport vesicles from the endoplasmic reticulum (ER). The coat has two main functions, the physical deformation of the endoplasmic reticulum membrane into vesicles and the selection of cargo molecules; Belongs to the SEC23/SEC24 family. SEC23 subfamily. (767 aa)
MAN1B1alpha-1,2-Mannosidase; Belongs to the glycosyl hydrolase 47 family. (728 aa)
CALRCalreticulin. (417 aa)
DNAJC5DnaJ heat shock protein family (Hsp40) member C5. (198 aa)
UBE2J1Ubiquitin conjugating enzyme E2 J1. (318 aa)
HSP90AB1HATPase_c domain-containing protein. (724 aa)
AMFRAutocrine motility factor receptor. (643 aa)
BAG2BCL2 associated athanogene 2. (211 aa)
NFE2L2Nuclear factor, erythroid 2 like 2. (606 aa)
LOC104666118UBA domain-containing protein. (301 aa)
SEC24ASEC24 homolog A, COPII coat complex component. (1093 aa)
BCAP31B cell receptor associated protein 31. (307 aa)
MARCHF6Membrane associated ring-CH-type finger 6. (910 aa)
Your Current Organism:
Rhinopithecus roxellana
NCBI taxonomy Id: 61622
Other names: Pygathrix roxellana, R. roxellana, golden snub-nosed monkey
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