(82 nodes) Peroxisome network (Rhinopithecus roxellana)

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

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proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	CAT	Catalase; Occurs in almost all aerobically respiring organisms and serves to protect cells from the toxic effects of hydrogen peroxide. (527 aa)
	PEX14	Peroxisomal biogenesis factor 14. (377 aa)
	NUDT7	Nudix hydrolase 7. (238 aa)
	XDH	Xanthine dehydrogenase. (1280 aa)
	ACSL3	Acyl-CoA synthetase long chain family member 3. (720 aa)
	NOS2	Nitric oxide synthase; Produces nitric oxide (NO). (1153 aa)
	PAOX	Amino_oxidase domain-containing protein. (511 aa)
	NUDT19	Nudix hydrolase 19. (375 aa)
	PEX2	Peroxisomal biogenesis factor 2. (305 aa)
	BAAT	Bile acid-CoA:amino acid N-acyltransferase. (418 aa)
	PRDX5	Peroxiredoxin; Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides; Belongs to the peroxiredoxin family. Prx5 subfamily. (215 aa)
	ACSL6	AMP-binding domain-containing protein. (722 aa)
	ACOX1	Acyl-coenzyme A oxidase; Belongs to the acyl-CoA oxidase family. (660 aa)
	PIPOX	Pipecolic acid and sarcosine oxidase. (390 aa)
	PXMP2	Peroxisomal membrane protein 2; Belongs to the peroxisomal membrane protein PXMP2/4 family. (195 aa)
	SCP2	Sterol carrier protein 2; Belongs to the thiolase-like superfamily. Thiolase family. (547 aa)
	HSD17B4	Hydroxysteroid 17-beta dehydrogenase 4. (759 aa)
	ACOT8	Acyl-CoA thioesterase 8. (328 aa)
	EPHX2	Epoxide hydrolase 2. (555 aa)
	SOD2	Superoxide dismutase; Destroys radicals which are normally produced within the cells and which are toxic to biological systems. Belongs to the iron/manganese superoxide dismutase family. (222 aa)
	PEX10	Peroxisomal biogenesis factor 10. (326 aa)
	PEX5	Peroxisomal biogenesis factor 5. (660 aa)
	CRAT	Carnitine O-acetyltransferase; Belongs to the carnitine/choline acetyltransferase family. (627 aa)
	DAO	D-amino acid oxidase. (384 aa)
	ACAA1	Acetyl-CoA acyltransferase 1; Belongs to the thiolase-like superfamily. Thiolase family. (424 aa)
	SLC25A17	Uncharacterized protein; Belongs to the mitochondrial carrier (TC 2.A.29) family. (307 aa)
	LOC104662710	Uncharacterized protein. (278 aa)
	GNPAT	Dihydroxyacetone phosphate acyltransferase. (684 aa)
	LOC104681892	Peroxiredoxin; Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides; Belongs to the peroxiredoxin family. Prx5 subfamily. (209 aa)
	AMACR	Alpha-methylacyl-CoA racemase. (382 aa)
	PEX13	Peroxisomal biogenesis factor 13. (403 aa)
	PEX1	Peroxisomal biogenesis factor 1. (1283 aa)
	HACL1	2-hydroxyacyl-CoA lyase 1; Belongs to the TPP enzyme family. (578 aa)
	FAR1	Fatty acyl-CoA reductase; Catalyzes the reduction of fatty acyl-CoA to fatty alcohols. (515 aa)
	ECI2	Enoyl-CoA delta isomerase 2. (391 aa)
	IDH1	Isocitrate dehydrogenase [NADP]; Belongs to the isocitrate and isopropylmalate dehydrogenases family. (414 aa)
	PXMP4	Peroxisomal membrane protein 4; Belongs to the peroxisomal membrane protein PXMP2/4 family. (212 aa)
	IDH2	Isocitrate dehydrogenase [NADP]; Belongs to the isocitrate and isopropylmalate dehydrogenases family. (449 aa)
	MPV17	Mitochondrial inner membrane protein MPV17; Belongs to the peroxisomal membrane protein PXMP2/4 family. (191 aa)
	PEX11G	Peroxisomal biogenesis factor 11 gamma. (236 aa)
	PEX6	Peroxisomal biogenesis factor 6. (980 aa)
	AGPS	Alkylglycerone-phosphate synthase; Catalyzes the exchange of an acyl for a long-chain alkyl group and the formation of the ether bond in the biosynthesis of ether phospholipids; Belongs to the FAD-binding oxidoreductase/transferase type 4 family. (686 aa)
	ACSL5	Acyl-CoA synthetase long chain family member 5. (725 aa)
	PEX11B	Peroxisomal biogenesis factor 11 beta. (259 aa)
	DDO	D-aspartate oxidase. (369 aa)
	DECR2	2,4-dienoyl-CoA reductase 2. (293 aa)
	ACSL4	Acyl-CoA synthetase long chain family member 4. (711 aa)
	PMVK	Phosphomevalonate kinase. (192 aa)
	ABCD4	ATP binding cassette subfamily D member 4. (606 aa)
	PEX7	Peroxisomal biogenesis factor 7. (323 aa)
	ABCD1	ATP binding cassette subfamily D member 1. (745 aa)
	HMGCLL1	3-hydroxymethyl-3-methylglutaryl-CoA lyase like 1. (304 aa)
	HAO1	Hydroxyacid oxidase 1. (370 aa)
	MPV17L2	MPV17 mitochondrial inner membrane protein like 2; Belongs to the peroxisomal membrane protein PXMP2/4 family. (206 aa)
	PEX5L	Peroxisomal biogenesis factor 5 like. (650 aa)
	PEX16	Peroxisomal membrane protein PEX16. (336 aa)
	PEX11A	Peroxisomal biogenesis factor 11 alpha. (247 aa)
	MLYCD	Malonyl-CoA decarboxylase. (463 aa)
	PEX3	Peroxisomal biogenesis factor 3. (373 aa)
	HMGCL	3-hydroxy-3-methylglutaryl-CoA lyase. (325 aa)
	MPV17L	MPV17 mitochondrial inner membrane protein like; Belongs to the peroxisomal membrane protein PXMP2/4 family. (188 aa)
	PEX12	Peroxisome assembly protein 12; Required for protein import into peroxisomes. Belongs to the pex2/pex10/pex12 family. (359 aa)
	ABCD3	ATP binding cassette subfamily D member 3. (659 aa)
	NUDT12	Nudix hydrolase 12. (462 aa)
	ACOX3	Acyl-coenzyme A oxidase; Belongs to the acyl-CoA oxidase family. (700 aa)
	EHHADH	Enoyl-CoA hydratase and 3-hydroxyacyl CoA dehydrogenase; Belongs to the enoyl-CoA hydratase/isomerase family. (723 aa)
	ACSL1	Acyl-CoA synthetase long chain family member 1. (721 aa)
	PECR	Peroxisomal trans-2-enoyl-CoA reductase. (322 aa)
	PHYH	Phytanoyl-CoA 2-hydroxylase. (338 aa)
	GSTK1	Glutathione S-transferase kappa. (226 aa)
	MVK	Mevalonate kinase; Catalyzes the phosphorylation of mevalonate to mevalonate 5- phosphate, a key step in isoprenoid and cholesterol biosynthesis. Belongs to the GHMP kinase family. Mevalonate kinase subfamily. (418 aa)
	PEX19	Uncharacterized protein. (363 aa)
	AGXT	Serine--pyruvate aminotransferase. (414 aa)
	ACOX2	Acyl-coenzyme A oxidase; Belongs to the acyl-CoA oxidase family. (681 aa)
	FAR2	Fatty acyl-CoA reductase; Catalyzes the reduction of fatty acyl-CoA to fatty alcohols. (515 aa)
	PRDX1	Peroxiredoxin 1. (199 aa)
	HAO2	Hydroxyacid oxidase 2. (367 aa)
	SLC27A2	Solute carrier family 27 member 2. (620 aa)
	ABCD2	ATP binding cassette subfamily D member 2. (740 aa)
	CROT	Carnitine O-octanoyltransferase; Belongs to the carnitine/choline acetyltransferase family. (612 aa)
	SOD1	Superoxide dismutase [Cu-Zn]; Destroys radicals which are normally produced within the cells and which are toxic to biological systems. Belongs to the Cu-Zn superoxide dismutase family. (154 aa)
	PEX26	Peroxisomal biogenesis factor 26. (305 aa)

Your Current Organism:

Rhinopithecus roxellana

NCBI taxonomy Id: 61622
Other names: Pygathrix roxellana, R. roxellana, golden snub-nosed monkey

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
ABCD1	ABCD2	ENSRROP00000027033	ENSRROP00000041249	ATP binding cassette subfamily D member 1.	ATP binding cassette subfamily D member 2.	0.717
ABCD1	ABCD3	ENSRROP00000027033	ENSRROP00000034355	ATP binding cassette subfamily D member 1.	ATP binding cassette subfamily D member 3.	0.791
ABCD1	ABCD4	ENSRROP00000027033	ENSRROP00000025742	ATP binding cassette subfamily D member 1.	ATP binding cassette subfamily D member 4.	0.633
ABCD1	ACAA1	ENSRROP00000027033	ENSRROP00000010960	ATP binding cassette subfamily D member 1.	Acetyl-CoA acyltransferase 1; Belongs to the thiolase-like superfamily. Thiolase family.	0.451
ABCD1	ACSL3	ENSRROP00000027033	ENSRROP00000002455	ATP binding cassette subfamily D member 1.	Acyl-CoA synthetase long chain family member 3.	0.422
ABCD1	ACSL4	ENSRROP00000027033	ENSRROP00000025331	ATP binding cassette subfamily D member 1.	Acyl-CoA synthetase long chain family member 4.	0.422
ABCD1	ECI2	ENSRROP00000027033	ENSRROP00000018560	ATP binding cassette subfamily D member 1.	Enoyl-CoA delta isomerase 2.	0.615
ABCD1	HSD17B4	ENSRROP00000027033	ENSRROP00000007576	ATP binding cassette subfamily D member 1.	Hydroxysteroid 17-beta dehydrogenase 4.	0.630
ABCD1	MPV17L2	ENSRROP00000027033	ENSRROP00000029712	ATP binding cassette subfamily D member 1.	MPV17 mitochondrial inner membrane protein like 2; Belongs to the peroxisomal membrane protein PXMP2/4 family.	0.470
ABCD1	PEX11A	ENSRROP00000027033	ENSRROP00000031213	ATP binding cassette subfamily D member 1.	Peroxisomal biogenesis factor 11 alpha.	0.648
ABCD1	PEX11B	ENSRROP00000027033	ENSRROP00000023160	ATP binding cassette subfamily D member 1.	Peroxisomal biogenesis factor 11 beta.	0.648
ABCD1	PEX11G	ENSRROP00000027033	ENSRROP00000021025	ATP binding cassette subfamily D member 1.	Peroxisomal biogenesis factor 11 gamma.	0.582
ABCD1	PEX12	ENSRROP00000027033	ENSRROP00000034205	ATP binding cassette subfamily D member 1.	Peroxisome assembly protein 12; Required for protein import into peroxisomes. Belongs to the pex2/pex10/pex12 family.	0.699
ABCD1	PEX13	ENSRROP00000027033	ENSRROP00000014333	ATP binding cassette subfamily D member 1.	Peroxisomal biogenesis factor 13.	0.765
ABCD1	PEX14	ENSRROP00000027033	ENSRROP00000000711	ATP binding cassette subfamily D member 1.	Peroxisomal biogenesis factor 14.	0.706
ABCD1	PEX16	ENSRROP00000027033	ENSRROP00000030354	ATP binding cassette subfamily D member 1.	Peroxisomal membrane protein PEX16.	0.655
ABCD1	PEX19	ENSRROP00000027033	ENSRROP00000037205	ATP binding cassette subfamily D member 1.	Uncharacterized protein.	0.827
ABCD1	PEX2	ENSRROP00000027033	ENSRROP00000003985	ATP binding cassette subfamily D member 1.	Peroxisomal biogenesis factor 2.	0.605
ABCD1	PEX26	ENSRROP00000027033	ENSRROP00000045131	ATP binding cassette subfamily D member 1.	Peroxisomal biogenesis factor 26.	0.420
ABCD1	PEX3	ENSRROP00000027033	ENSRROP00000031842	ATP binding cassette subfamily D member 1.	Peroxisomal biogenesis factor 3.	0.775