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| | LOC104679886 | Cytochrome c domain-containing protein; Electron carrier protein. The oxidized form of the cytochrome c heme group can accept an electron from the heme group of the cytochrome c1 subunit of cytochrome reductase. Cytochrome c then transfers this electron to the cytochrome oxidase complex, the final protein carrier in the mitochondrial electron-transport chain. (105 aa) |
| | TUBA1A | Tubulin alpha chain; Tubulin is the major constituent of microtubules. It binds two moles of GTP, one at an exchangeable site on the beta chain and one at a non-exchangeable site on the alpha chain. (451 aa) |
| | BAK1 | BCL2 antagonist/killer 1. (211 aa) |
| | DAB2IP | DAB2 interacting protein. (1189 aa) |
| | CAPN2 | Calpain 2; Belongs to the peptidase C2 family. (597 aa) |
| | CASP7 | Caspase 7; Belongs to the peptidase C14A family. (336 aa) |
| | LOC104681924 | Cytochrome c domain-containing protein; Electron carrier protein. The oxidized form of the cytochrome c heme group can accept an electron from the heme group of the cytochrome c1 subunit of cytochrome reductase. Cytochrome c then transfers this electron to the cytochrome oxidase complex, the final protein carrier in the mitochondrial electron-transport chain. (105 aa) |
| | PMAIP1 | Uncharacterized protein. (133 aa) |
| | AKT1 | Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily. (480 aa) |
| | IKBKG | Inhibitor of nuclear factor kappa B kinase regulatory subunit gamma. (487 aa) |
| | NGF | Nerve growth factor; Belongs to the NGF-beta family. (123 aa) |
| | ENSRROP00000002717 | Cytochrome c domain-containing protein; Electron carrier protein. The oxidized form of the cytochrome c heme group can accept an electron from the heme group of the cytochrome c1 subunit of cytochrome reductase. Cytochrome c then transfers this electron to the cytochrome oxidase complex, the final protein carrier in the mitochondrial electron-transport chain. (104 aa) |
| | PDPK1 | 3-phosphoinositide dependent protein kinase 1. (356 aa) |
| | RELA | RELA proto-oncogene, NF-kB subunit. (551 aa) |
| | ERN1 | Endoplasmic reticulum to nucleus signaling 1. (980 aa) |
| | MAPK8 | Mitogen-activated protein kinase. (427 aa) |
| | TNFRSF10A | TNF receptor superfamily member 10a. (469 aa) |
| | TNF | Tumor necrosis factor; Belongs to the tumor necrosis factor family. (233 aa) |
| | DFFA | DNA fragmentation factor subunit alpha. (331 aa) |
| | TUBA8 | Tubulin alpha chain; Tubulin is the major constituent of microtubules. It binds two moles of GTP, one at an exchangeable site on the beta chain and one at a non-exchangeable site on the alpha chain. (454 aa) |
| | DDIT3 | DNA damage-inducible transcript 3 protein; Multifunctional transcription factor in ER stress response. Plays an essential role in the response to a wide variety of cell stresses and induces cell cycle arrest and apoptosis in response to ER stress. Plays a dual role both as an inhibitor of CCAAT/enhancer- binding protein (C/EBP) function and as an activator of other genes. Acts as a dominant-negative regulator of C/EBP-induced transcription: dimerizes with members of the C/EBP family, impairs their association with C/EBP binding sites in the promoter regions, and inhibits the expression [...] (169 aa) |
| | BAX | BCL2 associated X, apoptosis regulator. (197 aa) |
| | LOC104661761 | Cytochrome c domain-containing protein; Electron carrier protein. The oxidized form of the cytochrome c heme group can accept an electron from the heme group of the cytochrome c1 subunit of cytochrome reductase. Cytochrome c then transfers this electron to the cytochrome oxidase complex, the final protein carrier in the mitochondrial electron-transport chain. (102 aa) |
| | ATF4 | Activating transcription factor 4. (351 aa) |
| | MAPK9 | Mitogen-activated protein kinase. (387 aa) |
| | CTSH | Cathepsin H; Belongs to the peptidase C1 family. (335 aa) |
| | CASP6 | Caspase 6; Belongs to the peptidase C14A family. (293 aa) |
| | TNFSF10 | Tumor necrosis factor ligand superfamily member. (281 aa) |
| | PTPN13 | Protein tyrosine phosphatase non-receptor type 13. (2492 aa) |
| | ACTB | Actin beta. (375 aa) |
| | TNFRSF1A | TNF receptor superfamily member 1A. (455 aa) |
| | CTSC | Cathepsin C; Belongs to the peptidase C1 family. (463 aa) |
| | PARP1 | Poly [ADP-ribose] polymerase; Poly-ADP-ribosyltransferase that mediates poly-ADP- ribosylation of proteins and plays a key role in DNA repair. (1014 aa) |
| | ACTG1 | Actin gamma 1. (375 aa) |
| | EIF2S1 | Eukaryotic translation initiation factor 2 subunit alpha. (295 aa) |
| | PIK3CA | Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit. (1068 aa) |
| | CASP2 | Caspase 2; Belongs to the peptidase C14A family. (452 aa) |
| | IL3 | Interleukin-3; Granulocyte/macrophage colony-stimulating factors are cytokines that act in hematopoiesis by controlling the production, differentiation, and function of 2 related white cell populations of the blood, the granulocytes and the monocytes-macrophages. Belongs to the IL-3 family. (152 aa) |
| | PIK3CD | Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit. (1044 aa) |
| | NTRK1 | Tyrosine-protein kinase receptor. (796 aa) |
| | CASP8 | Caspase 8; Belongs to the peptidase C14A family. (542 aa) |
| | MAP3K5 | Mitogen-activated protein kinase kinase kinase 5. (1374 aa) |
| | CSF2RB | Colony stimulating factor 2 receptor beta common subunit. (897 aa) |
| | MAP2K2 | Mitogen-activated protein kinase kinase 2; Belongs to the protein kinase superfamily. (399 aa) |
| | SEPTIN4-2 | Septin-type G domain-containing protein; Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. Septin GTPase family. (493 aa) |
| | BCL2A1 | BCL2 related protein A1. (175 aa) |
| | TUBA3D | Tubulin alpha chain; Tubulin is the major constituent of microtubules. It binds two moles of GTP, one at an exchangeable site on the beta chain and one at a non-exchangeable site on the alpha chain. (459 aa) |
| | DIABLO | Uncharacterized protein. (239 aa) |
| | GADD45A | Growth arrest and DNA damage inducible alpha. (165 aa) |
| | CASP3 | Uncharacterized protein; Belongs to the peptidase C14A family. (277 aa) |
| | CTSO | Cathepsin O; Belongs to the peptidase C1 family. (318 aa) |
| | DAXX | Daxx domain-containing protein. (744 aa) |
| | TRAF2 | TNF receptor-associated factor; Belongs to the TNF receptor-associated factor family. (519 aa) |
| | CTSB | Cathepsin B; Belongs to the peptidase C1 family. (339 aa) |
| | NRAS | NRAS proto-oncogene, GTPase. (189 aa) |
| | MCL1 | MCL1 apoptosis regulator, BCL2 family member. (350 aa) |
| | PARP3 | Poly [ADP-ribose] polymerase. (531 aa) |
| | BAD | BCL2 associated agonist of cell death. (167 aa) |
| | MAP2K1 | Mitogen-activated protein kinase kinase 1; Belongs to the protein kinase superfamily. (393 aa) |
| | AKT3 | Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily. (479 aa) |
| | MAP3K14 | Mitogen-activated protein kinase kinase kinase 14. (947 aa) |
| | PIK3R1 | Phosphoinositide-3-kinase regulatory subunit 1. (724 aa) |
| | APAF1 | Apoptotic protease-activating factor 1; Oligomeric Apaf-1 mediates the cytochrome c-dependent autocatalytic activation of pro-caspase-9 (Apaf-3), leading to the activation of caspase-3 and apoptosis. This activation requires ATP. (1248 aa) |
| | IL3RA | Interleukin 3 receptor subunit alpha. (378 aa) |
| | CTSD | Peptidase A1 domain-containing protein; Belongs to the peptidase A1 family. (594 aa) |
| | RIPK1 | Receptor interacting serine/threonine kinase 1. (671 aa) |
| | ITPR2 | Inositol 1,4,5-trisphosphate receptor type 2. (2700 aa) |
| | CTSV | Cathepsin V; Belongs to the peptidase C1 family. (334 aa) |
| | ENSRROP00000024190 | Protein kinase domain-containing protein. (137 aa) |
| | XIAP | X-linked inhibitor of apoptosis. (497 aa) |
| | CTSK | Cathepsin K; Belongs to the peptidase C1 family. (329 aa) |
| | MAPK1 | Mitogen-activated protein kinase. (330 aa) |
| | IKBKB | Inhibitor of nuclear factor kappa B kinase subunit beta. (789 aa) |
| | PARP2 | Poly [ADP-ribose] polymerase. (570 aa) |
| | NFKBIA | ANK_REP_REGION domain-containing protein. (343 aa) |
| | FAS | Fas cell surface death receptor. (331 aa) |
| | TP53 | Cellular tumor antigen p53; Acts as a tumor suppressor in many tumor types; induces growth arrest or apoptosis depending on the physiological circumstances and cell type. Involved in cell cycle regulation as a trans-activator that acts to negatively regulate cell division by controlling a set of genes required for this process. One of the activated genes is an inhibitor of cyclin-dependent kinases. Apoptosis induction seems to be mediated either by stimulation of BAX and FAS antigen expression, or by repression of Bcl-2 expression; Belongs to the p53 family. (393 aa) |
| | AIFM1 | Apoptosis inducing factor mitochondria associated 1. (613 aa) |
| | BCL2L1 | BCL2 like 1. (233 aa) |
| | LMNA | Lamin A/C; Belongs to the intermediate filament family. (728 aa) |
| | SPTA1 | Spectrin alpha, erythrocytic 1. (2427 aa) |
| | BCL2L11 | Bcl-2-like protein 11; Induces apoptosis and anoikis. Belongs to the Bcl-2 family. (198 aa) |
| | MAPK10 | Mitogen-activated protein kinase. (550 aa) |
| | CTSL | Cathepsin L; Belongs to the peptidase C1 family. (341 aa) |
| | FOS | Fos proto-oncogene, AP-1 transcription factor subunit. (380 aa) |
| | LMNB2 | Lamin B2; Belongs to the intermediate filament family. (601 aa) |
| | PRF1 | Perforin 1. (555 aa) |
| | EIF2AK3 | Eukaryotic translation initiation factor 2 alpha kinase 3. (1115 aa) |
| | LMNB1 | Lamin B1; Belongs to the intermediate filament family. (586 aa) |
| | GADD45G | Growth arrest and DNA damage inducible gamma. (159 aa) |
| | PIK3R3 | Phosphoinositide-3-kinase regulatory subunit 3. (461 aa) |
| | CTSZ | Cathepsin Z; Belongs to the peptidase C1 family. (370 aa) |
| | ATM | Serine-protein kinase ATM; Serine/threonine protein kinase which activates checkpoint signaling upon double strand breaks (DSBs), apoptosis and genotoxic stresses such as ionizing ultraviolet A light (UVA), thereby acting as a DNA damage sensor. Recognizes the substrate consensus sequence [ST]- Q. Phosphorylates 'Ser-139' of histone variant H2AX/H2AFX at double strand breaks (DSBs), thereby regulating DNA damage response mechanism. Also plays a role in pre-B cell allelic exclusion, a process leading to expression of a single immunoglobulin heavy chain allele to enforce clonality and mo [...] (3056 aa) |
| | MAPK3 | Mitogen-activated protein kinase; Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. MAP kinase subfamily. (379 aa) |
| | CTSS | Cathepsin S; Belongs to the peptidase C1 family. (331 aa) |
| | BIRC2 | Baculoviral IAP repeat containing 2. (618 aa) |
| | KRAS | KRAS proto-oncogene, GTPase. (189 aa) |
| | PARP4 | Poly [ADP-ribose] polymerase. (1691 aa) |
| | FADD | FAS-associated death domain protein; Apoptotic adaptor molecule that recruits caspase-8 or caspase-10 to the activated Fas (CD95) or TNFR-1 receptors. The resulting aggregate called the death-inducing signaling complex (DISC) performs caspase-8 proteolytic activation. Active caspase-8 initiates the subsequent cascade of caspases mediating apoptosis. Involved in interferon-mediated antiviral immune response, playing a role in the positive regulation of interferon signaling. (208 aa) |
| | BCL2 | BCL2 apoptosis regulator. (239 aa) |
| | HRAS | HRas proto-oncogene, GTPase. (189 aa) |
| | ITPR3 | Inositol 1,4,5-trisphosphate receptor type 3. (2703 aa) |
| | FASLG | Fas ligand; Belongs to the tumor necrosis factor family. (280 aa) |
| | TUBAL3 | Tubulin alpha chain; Tubulin is the major constituent of microtubules. It binds two moles of GTP, one at an exchangeable site on the beta chain and one at a non-exchangeable site on the alpha chain. (446 aa) |
| | CASP9 | Caspase 9; Belongs to the peptidase C14A family. (421 aa) |
| | GADD45B | Growth arrest and DNA damage inducible beta. (160 aa) |
| | CAPN1 | Calpain 1; Belongs to the peptidase C2 family. (714 aa) |
| | TUBA1C | Tubulin alpha chain; Tubulin is the major constituent of microtubules. It binds two moles of GTP, one at an exchangeable site on the beta chain and one at a non-exchangeable site on the alpha chain. (489 aa) |
| | RAF1 | Uncharacterized protein. (668 aa) |
| | HTRA2 | HtrA serine peptidase 2. (458 aa) |
| | CHUK | Component of inhibitor of nuclear factor kappa B kinase complex. (745 aa) |
| | SPTAN1 | Spectrin alpha, non-erythrocytic 1. (2498 aa) |
| | AKT2 | Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily. (481 aa) |
| | DFFB | DNA fragmentation factor subunit beta. (337 aa) |
| | CFLAR | CASP8 and FADD like apoptosis regulator; Belongs to the peptidase C14A family. (508 aa) |
| | TRAF1 | TNF receptor-associated factor. (416 aa) |
| | PIK3CB | Phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit beta; Belongs to the PI3/PI4-kinase family. (1073 aa) |
| | CASP10 | Caspase 10; Belongs to the peptidase C14A family. (522 aa) |
| | ITPR1 | Inositol 1,4,5-trisphosphate receptor type 1. (2714 aa) |
| | TUBA4A | Tubulin alpha chain; Tubulin is the major constituent of microtubules. It binds two moles of GTP, one at an exchangeable site on the beta chain and one at a non-exchangeable site on the alpha chain. (448 aa) |
| | NFKB1 | Nuclear factor kappa B subunit 1. (975 aa) |
| | GZMB | Granzyme B; Belongs to the peptidase S1 family. (281 aa) |
| | PIDD1 | P53-induced death domain protein 1. (910 aa) |
