STRINGSTRING
PPP1R14A PPP1R14A LOC104655958 LOC104655958 ADCY8 ADCY8 PLA2G4F PLA2G4F MYLK MYLK BRAF BRAF CALCB CALCB MYL9 MYL9 ADCY5 ADCY5 GUCY1A1 GUCY1A1 MYH10 MYH10 PLA2G2F PLA2G2F ARHGEF12 ARHGEF12 CALML3 CALML3 PRKACB PRKACB GNA13 GNA13 ARHGEF11 ARHGEF11 EDN1 EDN1 EDNRA EDNRA ADORA2A ADORA2A PPP1R12A PPP1R12A PRKCE PRKCE NPPA NPPA ADCY1 ADCY1 PRKACA PRKACA PRKCD PRKCD PRKCH PRKCH MYH9 MYH9 ADCY2 ADCY2 PLA2G4A PLA2G4A PLA2G5 PLA2G5 AVP AVP AGTR1 AGTR1 MAP2K2 MAP2K2 EDN2 EDN2 RHOA RHOA PLA2G12A-2 PLA2G12A-2 KCNMB2 KCNMB2 GNA11 GNA11 NPPB NPPB PRKCG PRKCG ADORA2B ADORA2B NPR1 NPR1 ADRA1B ADRA1B CALM3 CALM3 PLCB3 PLCB3 ENSRROP00000019822 ENSRROP00000019822 PRKCB PRKCB MAP2K1 MAP2K1 PLA2G4D PLA2G4D ROCK2 ROCK2 PLA2G6 PLA2G6 PLCB1 PLCB1 KCNMB4 KCNMB4 ITPR2 ITPR2 CACNA1D CACNA1D PRKCQ PRKCQ PTGIR PTGIR MYH14 MYH14 MYL6 MYL6 NPR2 NPR2 MAPK1 MAPK1 CACNA1S CACNA1S PLCB4 PLCB4 PLA2G4E PLA2G4E ADCY9 ADCY9 PLA2G12B PLA2G12B ARHGEF1 ARHGEF1 PPP1CB PPP1CB PLA2G4B PLA2G4B MYLK4 MYLK4 GUCY1B1 GUCY1B1 CACNA1C CACNA1C AVPR1B AVPR1B AVPR1A AVPR1A RAMP1 RAMP1 PPP1R12B PPP1R12B KCNMB1 KCNMB1 MAPK3 MAPK3 LOC104662055 LOC104662055 PPP1CA PPP1CA MYL6B-2 MYL6B-2 ADM ADM PLA2G2D PLA2G2D PLA2G2A PLA2G2A CACNA1F CACNA1F EDN3 EDN3 GNAQ GNAQ ADRA1A ADRA1A ITPR3 ITPR3 ADCY7 ADCY7 MYLK2 MYLK2 RAF1 RAF1 PLA2G4C PLA2G4C LOC104663799 LOC104663799 GNAS GNAS ACTG2 ACTG2 MRVI1 MRVI1 ARAF ARAF ADCY6 ADCY6 ADCY3 ADCY3 PRKG1 PRKG1 ROCK1 ROCK1 PPP1CC PPP1CC AGT AGT CALML6 CALML6 RAMP2 RAMP2 LOC104662101 LOC104662101 PRKCA PRKCA GNA12 GNA12 MYLK3 MYLK3 RAMP3 RAMP3 ITPR1 ITPR1 NPPC NPPC PLA2G3 PLA2G3 CALCRL CALCRL CALML4 CALML4 PLA2G2E PLA2G2E
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Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
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empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
PPP1R14AProtein phosphatase 1 regulatory inhibitor subunit 14A. (147 aa)
LOC104655958Uncharacterized protein. (423 aa)
ADCY8Adenylate cyclase type 8; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling. (1043 aa)
PLA2G4FPhospholipase A2. (849 aa)
MYLKMyosin light chain kinase. (1911 aa)
BRAFB-Raf proto-oncogene, serine/threonine kinase. (761 aa)
CALCBCalcitonin related polypeptide beta. (127 aa)
MYL9Myosin light chain 9. (172 aa)
ADCY5Adenylate cyclase 5; Belongs to the adenylyl cyclase class-4/guanylyl cyclase family. (864 aa)
GUCY1A1Guanylate cyclase 1 soluble subunit alpha 1; Belongs to the adenylyl cyclase class-4/guanylyl cyclase family. (690 aa)
MYH10Myosin heavy chain 10; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Myosin family. (2009 aa)
PLA2G2FPhospholipase A(2). (210 aa)
ARHGEF12Rho guanine nucleotide exchange factor 12. (1544 aa)
CALML3Calmodulin like 3; Belongs to the calmodulin family. (149 aa)
PRKACBProtein kinase cAMP-activated catalytic subunit beta; Belongs to the protein kinase superfamily. (398 aa)
GNA13G protein subunit alpha 13. (308 aa)
ARHGEF11Rho guanine nucleotide exchange factor 11. (1561 aa)
EDN1Endothelin 1. (211 aa)
EDNRAEndothelin receptor type A; Belongs to the G-protein coupled receptor 1 family. (427 aa)
ADORA2AAdenosine receptor A2; Receptor for adenosine. The activity of this receptor is mediated by G proteins which activate adenylyl cyclase. Belongs to the G-protein coupled receptor 1 family. (409 aa)
PPP1R12AProtein phosphatase 1 regulatory subunit. (907 aa)
PRKCEProtein kinase C epsilon type; Calcium-independent, phospholipid- and diacylglycerol (DAG)- dependent serine/threonine-protein kinase that plays essential roles in the regulation of multiple cellular processes linked to cytoskeletal proteins, such as cell adhesion, motility, migration and cell cycle, functions in neuron growth and ion channel regulation, and is involved in immune response, cancer cell invasion and regulation of apoptosis. Mediates cell adhesion to the extracellular matrix via integrin- dependent signaling, by mediating angiotensin-2-induced activation of integrin beta- [...] (737 aa)
NPPANatriuretic peptide A. (153 aa)
ADCY1Adenylate cyclase type 1; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling. (1075 aa)
PRKACAProtein kinase cAMP-activated catalytic subunit alpha; Belongs to the protein kinase superfamily. (351 aa)
PRKCDProtein kinase C delta type; Calcium-independent, phospholipid- and diacylglycerol (DAG)- dependent serine/threonine-protein kinase that plays contrasting roles in cell death and cell survival by functioning as a pro-apoptotic protein during DNA damage-induced apoptosis, but acting as an anti- apoptotic protein during cytokine receptor-initiated cell death, is involved in tumor suppression; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. PKC subfamily. (676 aa)
PRKCHProtein kinase C eta type; Calcium-independent, phospholipid- and diacylglycerol (DAG)- dependent serine/threonine-protein kinase that is involved in the regulation of cell differentiation in keratinocytes and pre-B cell receptor, mediates regulation of epithelial tight junction integrity and foam cell formation, and is required for glioblastoma proliferation and apoptosis prevention in MCF-7 cells. In keratinocytes, binds and activates the tyrosine kinase FYN, which in turn blocks epidermal growth factor receptor (EGFR) signaling and leads to keratinocyte growth arrest and differentia [...] (683 aa)
MYH9Myosin heavy chain 9; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Myosin family. (1960 aa)
ADCY2Adenylate cyclase type 2; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling. (1052 aa)
PLA2G4APhospholipase A2. (749 aa)
PLA2G5Phospholipase A(2). (138 aa)
AVPArginine vasopressin; Belongs to the vasopressin/oxytocin family. (164 aa)
AGTR1Angiotensin II receptor type 1; Belongs to the G-protein coupled receptor 1 family. (394 aa)
MAP2K2Mitogen-activated protein kinase kinase 2; Belongs to the protein kinase superfamily. (399 aa)
EDN2Endothelin 2. (178 aa)
RHOARas homolog family member A. (193 aa)
PLA2G12A-2Uncharacterized protein. (226 aa)
KCNMB2Uncharacterized protein. (216 aa)
GNA11G protein subunit alpha 11. (359 aa)
NPPBNatriuretic peptide B. (134 aa)
PRKCGProtein kinase C; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. PKC subfamily. (697 aa)
ADORA2BAdenosine receptor A2; Receptor for adenosine. The activity of this receptor is mediated by G proteins which activate adenylyl cyclase. Belongs to the G-protein coupled receptor 1 family. (331 aa)
NPR1Guanylate cyclase. (1284 aa)
ADRA1BAdrenoceptor alpha 1B. (512 aa)
CALM3Calmodulin 1; Belongs to the calmodulin family. (149 aa)
PLCB31-phosphatidylinositol 4,5-bisphosphate phosphodiesterase; The production of the second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3) is mediated by activated phosphatidylinositol-specific phospholipase C enzymes. (1234 aa)
ENSRROP00000019822Uncharacterized protein; Belongs to the calmodulin family. (141 aa)
PRKCBNon-specific serine/threonine protein kinase. (590 aa)
MAP2K1Mitogen-activated protein kinase kinase 1; Belongs to the protein kinase superfamily. (393 aa)
PLA2G4DPhospholipase A2. (816 aa)
ROCK2Rho-associated protein kinase; Protein kinase which is a key regulator of actin cytoskeleton and cell polarity. (1383 aa)
PLA2G6Phospholipase A2 group VI. (806 aa)
PLCB11-phosphatidylinositol 4,5-bisphosphate phosphodiesterase; The production of the second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3) is mediated by activated phosphatidylinositol-specific phospholipase C enzymes. (1114 aa)
KCNMB4Potassium calcium-activated channel subfamily M regulatory beta subunit 4. (210 aa)
ITPR2Inositol 1,4,5-trisphosphate receptor type 2. (2700 aa)
CACNA1DVoltage-dependent L-type calcium channel subunit alpha; Voltage-sensitive calcium channels (VSCC) mediate the entry of calcium ions into excitable cells and are also involved in a variety of calcium-dependent processes, including muscle contraction, hormone or neurotransmitter release, gene expression, cell motility, cell division and cell death; Belongs to the calcium channel alpha-1 subunit (TC 1.A.1.11) family. (2181 aa)
PRKCQProtein kinase C; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. PKC subfamily. (710 aa)
PTGIRProstaglandin I2 receptor. (386 aa)
MYH14Myosin heavy chain 14; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Myosin family. (2028 aa)
MYL6Uncharacterized protein. (226 aa)
NPR2Guanylate cyclase. (1047 aa)
MAPK1Mitogen-activated protein kinase. (330 aa)
CACNA1SVoltage-dependent L-type calcium channel subunit alpha; Voltage-sensitive calcium channels (VSCC) mediate the entry of calcium ions into excitable cells and are also involved in a variety of calcium-dependent processes, including muscle contraction, hormone or neurotransmitter release, gene expression, cell motility, cell division and cell death; Belongs to the calcium channel alpha-1 subunit (TC 1.A.1.11) family. (1873 aa)
PLCB41-phosphatidylinositol 4,5-bisphosphate phosphodiesterase; The production of the second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3) is mediated by activated phosphatidylinositol-specific phospholipase C enzymes. (1225 aa)
PLA2G4EPhospholipase A2. (869 aa)
ADCY9Adenylate cyclase 9; Belongs to the adenylyl cyclase class-4/guanylyl cyclase family. (1353 aa)
PLA2G12BPhospholipase A2 group XIIB. (195 aa)
ARHGEF1Rho guanine nucleotide exchange factor 1. (968 aa)
PPP1CBSerine/threonine-protein phosphatase; Belongs to the PPP phosphatase family. (373 aa)
PLA2G4BPhospholipase A2. (798 aa)
MYLK4Myosin light chain kinase family member 4; Belongs to the protein kinase superfamily. (388 aa)
GUCY1B1Guanylate cyclase 1 soluble subunit beta 1; Belongs to the adenylyl cyclase class-4/guanylyl cyclase family. (642 aa)
CACNA1CCa_chan_IQ domain-containing protein. (829 aa)
AVPR1BVasopressin V1b receptor; Receptor for arginine vasopressin. The activity of this receptor is mediated by G proteins which activate a phosphatidyl- inositol-calcium second messenger system. Belongs to the G-protein coupled receptor 1 family. Vasopressin/oxytocin receptor subfamily. (424 aa)
AVPR1AVasopressin V1a receptor; Receptor for arginine vasopressin. The activity of this receptor is mediated by G proteins which activate a phosphatidyl- inositol-calcium second messenger system. Belongs to the G-protein coupled receptor 1 family. Vasopressin/oxytocin receptor subfamily. (421 aa)
RAMP1Receptor activity modifying protein 1. (148 aa)
PPP1R12BProtein phosphatase 1 regulatory subunit. (1058 aa)
KCNMB1Potassium calcium-activated channel subfamily M regulatory beta subunit 1. (204 aa)
MAPK3Mitogen-activated protein kinase; Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. MAP kinase subfamily. (379 aa)
LOC104662055EF-hand domain-containing protein; Belongs to the calmodulin family. (75 aa)
PPP1CASerine/threonine-protein phosphatase; Belongs to the PPP phosphatase family. (367 aa)
MYL6B-2EF-hand domain-containing protein. (154 aa)
ADMAdrenomedullin. (184 aa)
PLA2G2DPhospholipase A(2). (145 aa)
PLA2G2APhospholipase A(2). (144 aa)
CACNA1FVoltage-dependent L-type calcium channel subunit alpha; Voltage-sensitive calcium channels (VSCC) mediate the entry of calcium ions into excitable cells and are also involved in a variety of calcium-dependent processes, including muscle contraction, hormone or neurotransmitter release, gene expression, cell motility, cell division and cell death; Belongs to the calcium channel alpha-1 subunit (TC 1.A.1.11) family. (1971 aa)
EDN3Endothelin 3. (211 aa)
GNAQG protein subunit alpha q. (359 aa)
ADRA1AAdrenoceptor alpha 1A. (455 aa)
ITPR3Inositol 1,4,5-trisphosphate receptor type 3. (2703 aa)
ADCY7Adenylate cyclase type 7; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling. (1095 aa)
MYLK2Myosin light chain kinase 2. (595 aa)
RAF1Uncharacterized protein. (668 aa)
PLA2G4CPhospholipase A2 group IVC. (551 aa)
LOC104663799Uncharacterized protein. (246 aa)
GNASGNAS complex locus. (1041 aa)
ACTG2Actin gamma 2, smooth muscle. (376 aa)
MRVI1Murine retrovirus integration site 1 homolog. (911 aa)
ARAFA-Raf proto-oncogene, serine/threonine kinase. (606 aa)
ADCY6Adenylate cyclase 6; Belongs to the adenylyl cyclase class-4/guanylyl cyclase family. (603 aa)
ADCY3Adenylate cyclase type 3; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling. (1147 aa)
PRKG1Protein kinase cGMP-dependent 1; Belongs to the protein kinase superfamily. (463 aa)
ROCK1Rho-associated protein kinase; Protein kinase which is a key regulator of actin cytoskeleton and cell polarity. (1368 aa)
PPP1CCSerine/threonine-protein phosphatase; Belongs to the PPP phosphatase family. (337 aa)
AGTAngiotensinogen; Belongs to the serpin family. (485 aa)
CALML6Calmodulin like 6. (181 aa)
RAMP2Receptor activity modifying protein 2. (175 aa)
LOC104662101Uncharacterized protein; Belongs to the cytochrome P450 family. (519 aa)
PRKCAProtein kinase C; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. PKC subfamily. (672 aa)
GNA12G protein subunit alpha 12. (381 aa)
MYLK3Myosin light chain kinase 3. (818 aa)
RAMP3Receptor activity modifying protein 3. (151 aa)
ITPR1Inositol 1,4,5-trisphosphate receptor type 1. (2714 aa)
NPPCNatriuretic peptide C. (126 aa)
PLA2G3Phospholipase A2 group III. (506 aa)
CALCRLCalcitonin receptor like receptor; Belongs to the G-protein coupled receptor 2 family. (458 aa)
CALML4Calmodulin like 4. (192 aa)
PLA2G2EPhospholipase A(2). (142 aa)
Your Current Organism:
Rhinopithecus roxellana
NCBI taxonomy Id: 61622
Other names: Pygathrix roxellana, R. roxellana, golden snub-nosed monkey
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