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| | GSK3B | Glycogen synthase kinase 3 beta; Belongs to the protein kinase superfamily. (309 aa) |
| | LOC104677263 | Uncharacterized protein; Belongs to the SKP1 family. (155 aa) |
| | CAMK2D | Calcium/calmodulin dependent protein kinase II delta. (533 aa) |
| | CREBBP | CREB binding protein. (2442 aa) |
| | WNT1 | Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (370 aa) |
| | RNF43 | RING-type domain-containing protein. (740 aa) |
| | FZD4 | Frizzled class receptor 4; Belongs to the G-protein coupled receptor Fz/Smo family. (537 aa) |
| | SFRP2 | Secreted frizzled related protein 2. (295 aa) |
| | FZD5 | Frizzled class receptor 5; Belongs to the G-protein coupled receptor Fz/Smo family. (585 aa) |
| | SERPINF1 | Serpin family F member 1; Belongs to the serpin family. (418 aa) |
| | WNT6 | Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (369 aa) |
| | WNT2 | Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (360 aa) |
| | DKK4 | Dickkopf WNT signaling pathway inhibitor 4. (224 aa) |
| | LOC104682414 | WD_REPEATS_REGION domain-containing protein. (489 aa) |
| | MAPK8 | Mitogen-activated protein kinase. (427 aa) |
| | ROR2 | Receptor tyrosine kinase like orphan receptor 2; Belongs to the protein kinase superfamily. Tyr protein kinase family. ROR subfamily. (942 aa) |
| | NFATC4 | Nuclear factor of activated T cells 4. (914 aa) |
| | CTNNBIP1 | Catenin beta interacting protein 1. (81 aa) |
| | PRKACB | Protein kinase cAMP-activated catalytic subunit beta; Belongs to the protein kinase superfamily. (398 aa) |
| | PSEN1 | Presenilin; Probable subunit of the gamma-secretase complex, an endoprotease complex that catalyzes the intramembrane cleavage of integral membrane proteins such as Notch receptors. Belongs to the peptidase A22A family. (465 aa) |
| | RSPO2 | R-spondin 2. (243 aa) |
| | MAPK9 | Mitogen-activated protein kinase. (387 aa) |
| | SENP2 | ULP_PROTEASE domain-containing protein. (588 aa) |
| | DAAM2 | Dishevelled associated activator of morphogenesis 2. (1077 aa) |
| | INVS | Inversin. (1066 aa) |
| | NFATC1 | Nuclear factor of activated T cells 1. (895 aa) |
| | FRAT1 | FRAT regulator of WNT signaling pathway 1. (242 aa) |
| | RBX1 | Ring-box 1. (108 aa) |
| | PPARD | Peroxisome proliferator activated receptor delta. (441 aa) |
| | TCF7L1 | Transcription factor 7 like 1. (562 aa) |
| | CUL1 | Cullin 1; Belongs to the cullin family. (776 aa) |
| | LGR5 | Leucine rich repeat containing G protein-coupled receptor 5. (907 aa) |
| | PRKACA | Protein kinase cAMP-activated catalytic subunit alpha; Belongs to the protein kinase superfamily. (351 aa) |
| | WNT8A | Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (351 aa) |
| | BTRC | Beta-transducin repeat containing E3 ubiquitin protein ligase. (605 aa) |
| | NLK | Mitogen-activated protein kinase; Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. MAP kinase subfamily. (527 aa) |
| | SFRP5 | Secreted frizzled related protein 5. (319 aa) |
| | TBL1X | Transducin beta like 1 X-linked. (575 aa) |
| | AXIN2 | Axin 2. (843 aa) |
| | WNT11 | Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (354 aa) |
| | PPP3R1 | Uncharacterized protein. (189 aa) |
| | WNT9A | Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (365 aa) |
| | WNT10A | Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (417 aa) |
| | MAP3K7 | Mitogen-activated protein kinase kinase kinase 7; Belongs to the protein kinase superfamily. STE Ser/Thr protein kinase family. MAP kinase kinase kinase subfamily. (616 aa) |
| | SOX17 | SRY-box transcription factor 17. (412 aa) |
| | PRICKLE2 | Prickle planar cell polarity protein 2. (609 aa) |
| | RHOA | Ras homolog family member A. (193 aa) |
| | WNT5A | Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (380 aa) |
| | PPP3CB | Serine/threonine-protein phosphatase. (521 aa) |
| | WNT16 | Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (365 aa) |
| | MYC | Myc proto-oncogene protein; Transcription factor that binds DNA in a non-specific manner, yet also specifically recognizes the core sequence 5'-CAC[GA]TG-3'. Activates the transcription of growth-related genes. (439 aa) |
| | NKD1 | NKD inhibitor of WNT signaling pathway 1. (470 aa) |
| | WIF1 | WNT inhibitory factor 1. (379 aa) |
| | CACYBP | Uncharacterized protein. (228 aa) |
| | CCND1 | Cyclin D1; Belongs to the cyclin family. (253 aa) |
| | PRKCG | Protein kinase C; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. PKC subfamily. (697 aa) |
| | CSNK1A1 | Casein kinase 1 alpha 1; Belongs to the protein kinase superfamily. (372 aa) |
| | WNT9B | Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (357 aa) |
| | WNT2B | Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (391 aa) |
| | CAMK2A | Calcium/calmodulin dependent protein kinase II alpha; Belongs to the protein kinase superfamily. (489 aa) |
| | FZD6 | Frizzled class receptor 6; Belongs to the G-protein coupled receptor Fz/Smo family. (706 aa) |
| | PLCB3 | 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase; The production of the second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3) is mediated by activated phosphatidylinositol-specific phospholipase C enzymes. (1234 aa) |
| | DVL2 | Dishevelled segment polarity protein 2. (736 aa) |
| | DVL3 | Dishevelled segment polarity protein 3. (718 aa) |
| | PRKCB | Non-specific serine/threonine protein kinase. (590 aa) |
| | NFATC3 | Nuclear factor of activated T cells 3. (1075 aa) |
| | APC2 | APC regulator of WNT signaling pathway 2. (2119 aa) |
| | WNT8B | Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (353 aa) |
| | PORCN | Porcupine O-acyltransferase; Belongs to the membrane-bound acyltransferase family. (461 aa) |
| | FZD9 | Frizzled class receptor 9; Belongs to the G-protein coupled receptor Fz/Smo family. (510 aa) |
| | RSPO3 | R-spondin 3. (293 aa) |
| | ROCK2 | Rho-associated protein kinase; Protein kinase which is a key regulator of actin cytoskeleton and cell polarity. (1383 aa) |
| | CCND2 | Cyclin N-terminal domain-containing protein; Belongs to the cyclin family. (289 aa) |
| | CXXC4 | CXXC finger protein 4. (371 aa) |
| | RSPO4 | R-spondin 4. (234 aa) |
| | LGR6 | Leucine rich repeat containing G protein-coupled receptor 6. (967 aa) |
| | PLCB1 | 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase; The production of the second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3) is mediated by activated phosphatidylinositol-specific phospholipase C enzymes. (1114 aa) |
| | NOTUM | Notum, palmitoleoyl-protein carboxylesterase. (477 aa) |
| | SIAH1 | E3 ubiquitin-protein ligase; E3 ubiquitin-protein ligase that mediates ubiquitination and subsequent proteasomal degradation of target proteins. E3 ubiquitin ligases accept ubiquitin from an E2 ubiquitin-conjugating enzyme in the form of a thioester and then directly transfers the ubiquitin to targeted substrates. (313 aa) |
| | FZD7 | Frizzled class receptor 7; Belongs to the G-protein coupled receptor Fz/Smo family. (575 aa) |
| | WNT4 | Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (345 aa) |
| | FZD2 | Frizzled class receptor 2; Belongs to the G-protein coupled receptor Fz/Smo family. (571 aa) |
| | PRICKLE3 | Prickle planar cell polarity protein 3. (621 aa) |
| | LRP5 | Low-density lipoprotein receptor-related protein; Component of the Wnt-Fzd-LRP5-LRP6 complex that triggers beta-catenin signaling through inducing aggregation of receptor-ligand complexes into ribosome-sized signalsomes. Belongs to the LDLR family. (1611 aa) |
| | DKK2 | Dickkopf_N domain-containing protein. (185 aa) |
| | GPC4 | Glypican 4; Cell surface proteoglycan that bears heparan sulfate. Belongs to the glypican family. (556 aa) |
| | PLCB4 | 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase; The production of the second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3) is mediated by activated phosphatidylinositol-specific phospholipase C enzymes. (1225 aa) |
| | AXIN1 | Axin 1. (867 aa) |
| | PPP3CC | Serine/threonine-protein phosphatase. (520 aa) |
| | TP53 | Cellular tumor antigen p53; Acts as a tumor suppressor in many tumor types; induces growth arrest or apoptosis depending on the physiological circumstances and cell type. Involved in cell cycle regulation as a trans-activator that acts to negatively regulate cell division by controlling a set of genes required for this process. One of the activated genes is an inhibitor of cyclin-dependent kinases. Apoptosis induction seems to be mediated either by stimulation of BAX and FAS antigen expression, or by repression of Bcl-2 expression; Belongs to the p53 family. (393 aa) |
| | DKK1 | Dickkopf WNT signaling pathway inhibitor 1. (266 aa) |
| | RUVBL1 | RuvB-like helicase; Proposed core component of the chromatin remodeling Ino80 complex which exhibits DNA- and nucleosome-activated ATPase activity and catalyzes ATP-dependent nucleosome sliding. (456 aa) |
| | RYK | Receptor like tyrosine kinase. (623 aa) |
| | WNT3A | Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (352 aa) |
| | EP300 | E1A binding protein p300. (2413 aa) |
| | MAPK10 | Mitogen-activated protein kinase. (550 aa) |
| | WNT3 | Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (355 aa) |
| | CTNNB1 | Catenin beta 1. (781 aa) |
| | CSNK1E | Protein kinase domain-containing protein; Belongs to the protein kinase superfamily. (416 aa) |
| | LEF1 | Lymphoid enhancer binding factor 1. (399 aa) |
| | ROR1 | Receptor tyrosine kinase like orphan receptor 1; Belongs to the protein kinase superfamily. Tyr protein kinase family. ROR subfamily. (925 aa) |
| | PRICKLE1 | Prickle planar cell polarity protein 1. (831 aa) |
| | CBY1 | Chibby family member 1, beta catenin antagonist. (169 aa) |
| | FZD10 | Frizzled class receptor 10; Belongs to the G-protein coupled receptor Fz/Smo family. (583 aa) |
| | CAMK2B | Calcium/calmodulin dependent protein kinase II beta. (653 aa) |
| | CCND3 | Cyclin D3; Belongs to the cyclin family. (292 aa) |
| | CSNK1A1L | Casein kinase 1 alpha 1 like. (243 aa) |
| | CTBP2 | C-terminal binding protein 2. (985 aa) |
| | RSPO1 | R-spondin 1. (262 aa) |
| | SFRP1 | Secreted frizzled related protein 1. (314 aa) |
| | CAMK2G | Calcium/calmodulin dependent protein kinase II gamma. (559 aa) |
| | ZNRF3 | Zinc and ring finger 3. (919 aa) |
| | CSNK2A1 | Protein kinase domain-containing protein; Belongs to the protein kinase superfamily. (391 aa) |
| | FZD3 | Frizzled class receptor 3; Belongs to the G-protein coupled receptor Fz/Smo family. (666 aa) |
| | LRP6 | Low-density lipoprotein receptor-related protein; Component of the Wnt-Fzd-LRP5-LRP6 complex that triggers beta-catenin signaling through inducing aggregation of receptor-ligand complexes into ribosome-sized signalsomes. Belongs to the LDLR family. (1613 aa) |
| | CER1 | Cerberus 1, DAN family BMP antagonist. (267 aa) |
| | RAC2 | Rac family small GTPase 2. (192 aa) |
| | NFATC2 | Nuclear factor of activated T cells 2. (932 aa) |
| | TBL1XR1 | Transducin beta like 1 X-linked receptor 1. (514 aa) |
| | LGR4 | Leucine rich repeat containing G protein-coupled receptor 4. (951 aa) |
| | CCN4 | Cellular communication network factor 4. (367 aa) |
| | PRKCA | Protein kinase C; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. PKC subfamily. (672 aa) |
| | CHD8 | Chromodomain-helicase-DNA-binding protein 8; DNA helicase that acts as a chromatin remodeling factor and regulates transcription. Acts as a transcription repressor by remodeling chromatin structure and recruiting histone H1 to target genes. Suppresses p53/TP53-mediated apoptosis by recruiting histone H1 and preventing p53/TP53 transactivation activity. Acts as a negative regulator of Wnt signaling pathway by regulating beta-catenin (CTNNB1) activity. Negatively regulates CTNNB1-targeted gene expression by being recruited specifically to the promoter regions of several CTNNB1 responsive [...] (2582 aa) |
| | SKP1 | S-phase kinase associated protein 1; Belongs to the SKP1 family. (163 aa) |
| | SOST | Sclerostin. (213 aa) |
| | CSNK2B | Uncharacterized protein. (298 aa) |
| | MMP7 | Matrix metallopeptidase 7. (270 aa) |
| | WNT7A | Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (349 aa) |
| | WNT7B | Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (348 aa) |
| | FOSL1 | FOS like 1, AP-1 transcription factor subunit. (271 aa) |
| | SMAD4 | Mothers against decapentaplegic homolog. (552 aa) |
| | WNT10B | Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (389 aa) |
| | DAAM1 | Dishevelled associated activator of morphogenesis 1. (1078 aa) |
| | SFRP4 | Secreted frizzled related protein 4. (368 aa) |
| | CTBP1 | C-terminal binding protein 1; Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family. (448 aa) |
| | PRICKLE4 | Uncharacterized protein. (345 aa) |
| | BAMBI | BMP and activin membrane-bound inhibitor homolog; Negatively regulates TGF-beta signaling. Belongs to the BAMBI family. (260 aa) |
| | PPP3CA | Serine/threonine-protein phosphatase. (417 aa) |
| | VANGL1 | Vang-like protein. (524 aa) |
| | WNT5B | Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (400 aa) |
