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CAMK2D CAMK2D ADCY8 ADCY8 PLA2G4F PLA2G4F PLD1-2 PLD1-2 MAP2K7 MAP2K7 GNRHR GNRHR ADCY5 ADCY5 MAPK8 MAPK8 CALML3 CALML3 PRKACB PRKACB ATF4 ATF4 MAPK9 MAPK9 ADCY1 ADCY1 PRKACA PRKACA HBEGF HBEGF PRKCD PRKCD MAP2K6 MAP2K6 ADCY2 ADCY2 PLA2G4A PLA2G4A SOS1 SOS1 MAP2K2 MAP2K2 MMP14 MMP14 GNA11 GNA11 MAP2K4 MAP2K4 CAMK2A CAMK2A NRAS NRAS CALM3 CALM3 PLCB3 PLCB3 ENSRROP00000019822 ENSRROP00000019822 SRC SRC PRKCB PRKCB MAP2K1 MAP2K1 PLA2G4D PLA2G4D PLCB1 PLCB1 ITPR2 ITPR2 CACNA1D CACNA1D FSHB FSHB MAP3K1 MAP3K1 MAPK1 MAPK1 CACNA1S CACNA1S MAP2K3 MAP2K3 MAPK14 MAPK14 SOS2 SOS2 PLCB4 PLCB4 PLA2G4E PLA2G4E ADCY9 ADCY9 LHB LHB PLA2G4B PLA2G4B MAPK10 MAPK10 CACNA1C CACNA1C GNRH2 GNRH2 MMP2 MMP2 MAPK3 MAPK3 LOC104662055 LOC104662055 KRAS KRAS MAP3K3 MAP3K3 GRB2 GRB2 CACNA1F CACNA1F CAMK2B CAMK2B ELK1 ELK1 CDC42 CDC42 GNAQ GNAQ HRAS HRAS ITPR3 ITPR3 ADCY7 ADCY7 EGFR EGFR RAF1 RAF1 PLA2G4C PLA2G4C LOC104663799 LOC104663799 CAMK2G CAMK2G PLD2 PLD2 GNAS GNAS MAP3K4 MAP3K4 PTK2B PTK2B GNRH1 GNRH1 MAP3K2 MAP3K2 ADCY6 ADCY6 ADCY3 ADCY3 MAPK7 MAPK7 CALML6 CALML6 PRKCA PRKCA EGR1 EGR1 ITPR1 ITPR1 CALML4 CALML4
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
CAMK2DCalcium/calmodulin dependent protein kinase II delta. (533 aa)
ADCY8Adenylate cyclase type 8; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling. (1043 aa)
PLA2G4FPhospholipase A2. (849 aa)
PLD1-2Uncharacterized protein. (57 aa)
MAP2K7Mitogen-activated protein kinase kinase 7. (403 aa)
GNRHRGonadotropin releasing hormone receptor; Belongs to the G-protein coupled receptor 1 family. (328 aa)
ADCY5Adenylate cyclase 5; Belongs to the adenylyl cyclase class-4/guanylyl cyclase family. (864 aa)
MAPK8Mitogen-activated protein kinase. (427 aa)
CALML3Calmodulin like 3; Belongs to the calmodulin family. (149 aa)
PRKACBProtein kinase cAMP-activated catalytic subunit beta; Belongs to the protein kinase superfamily. (398 aa)
ATF4Activating transcription factor 4. (351 aa)
MAPK9Mitogen-activated protein kinase. (387 aa)
ADCY1Adenylate cyclase type 1; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling. (1075 aa)
PRKACAProtein kinase cAMP-activated catalytic subunit alpha; Belongs to the protein kinase superfamily. (351 aa)
HBEGFHeparin binding EGF like growth factor. (208 aa)
PRKCDProtein kinase C delta type; Calcium-independent, phospholipid- and diacylglycerol (DAG)- dependent serine/threonine-protein kinase that plays contrasting roles in cell death and cell survival by functioning as a pro-apoptotic protein during DNA damage-induced apoptosis, but acting as an anti- apoptotic protein during cytokine receptor-initiated cell death, is involved in tumor suppression; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. PKC subfamily. (676 aa)
MAP2K6Mitogen-activated protein kinase kinase 6; Belongs to the protein kinase superfamily. (334 aa)
ADCY2Adenylate cyclase type 2; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling. (1052 aa)
PLA2G4APhospholipase A2. (749 aa)
SOS1SOS Ras/Rac guanine nucleotide exchange factor 1. (1333 aa)
MAP2K2Mitogen-activated protein kinase kinase 2; Belongs to the protein kinase superfamily. (399 aa)
MMP14Matrix metallopeptidase 14. (582 aa)
GNA11G protein subunit alpha 11. (359 aa)
MAP2K4Mitogen-activated protein kinase kinase 4; Belongs to the protein kinase superfamily. (410 aa)
CAMK2ACalcium/calmodulin dependent protein kinase II alpha; Belongs to the protein kinase superfamily. (489 aa)
NRASNRAS proto-oncogene, GTPase. (189 aa)
CALM3Calmodulin 1; Belongs to the calmodulin family. (149 aa)
PLCB31-phosphatidylinositol 4,5-bisphosphate phosphodiesterase; The production of the second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3) is mediated by activated phosphatidylinositol-specific phospholipase C enzymes. (1234 aa)
ENSRROP00000019822Uncharacterized protein; Belongs to the calmodulin family. (141 aa)
SRCTyrosine-protein kinase. (540 aa)
PRKCBNon-specific serine/threonine protein kinase. (590 aa)
MAP2K1Mitogen-activated protein kinase kinase 1; Belongs to the protein kinase superfamily. (393 aa)
PLA2G4DPhospholipase A2. (816 aa)
PLCB11-phosphatidylinositol 4,5-bisphosphate phosphodiesterase; The production of the second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3) is mediated by activated phosphatidylinositol-specific phospholipase C enzymes. (1114 aa)
ITPR2Inositol 1,4,5-trisphosphate receptor type 2. (2700 aa)
CACNA1DVoltage-dependent L-type calcium channel subunit alpha; Voltage-sensitive calcium channels (VSCC) mediate the entry of calcium ions into excitable cells and are also involved in a variety of calcium-dependent processes, including muscle contraction, hormone or neurotransmitter release, gene expression, cell motility, cell division and cell death; Belongs to the calcium channel alpha-1 subunit (TC 1.A.1.11) family. (2181 aa)
FSHBFollicle stimulating hormone subunit beta. (129 aa)
MAP3K1Mitogen-activated protein kinase kinase kinase 1. (1449 aa)
MAPK1Mitogen-activated protein kinase. (330 aa)
CACNA1SVoltage-dependent L-type calcium channel subunit alpha; Voltage-sensitive calcium channels (VSCC) mediate the entry of calcium ions into excitable cells and are also involved in a variety of calcium-dependent processes, including muscle contraction, hormone or neurotransmitter release, gene expression, cell motility, cell division and cell death; Belongs to the calcium channel alpha-1 subunit (TC 1.A.1.11) family. (1873 aa)
MAP2K3Mitogen-activated protein kinase kinase 3; Belongs to the protein kinase superfamily. (394 aa)
MAPK14Mitogen-activated protein kinase. (360 aa)
SOS2SOS Ras/Rho guanine nucleotide exchange factor 2. (1332 aa)
PLCB41-phosphatidylinositol 4,5-bisphosphate phosphodiesterase; The production of the second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3) is mediated by activated phosphatidylinositol-specific phospholipase C enzymes. (1225 aa)
PLA2G4EPhospholipase A2. (869 aa)
ADCY9Adenylate cyclase 9; Belongs to the adenylyl cyclase class-4/guanylyl cyclase family. (1353 aa)
LHBCys_knot domain-containing protein. (141 aa)
PLA2G4BPhospholipase A2. (798 aa)
MAPK10Mitogen-activated protein kinase. (550 aa)
CACNA1CCa_chan_IQ domain-containing protein. (829 aa)
GNRH2Gonadoliberin; Stimulates the secretion of gonadotropins. Belongs to the GnRH family. (118 aa)
MMP2Matrix metallopeptidase 2. (660 aa)
MAPK3Mitogen-activated protein kinase; Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. MAP kinase subfamily. (379 aa)
LOC104662055EF-hand domain-containing protein; Belongs to the calmodulin family. (75 aa)
KRASKRAS proto-oncogene, GTPase. (189 aa)
MAP3K3Mitogen-activated protein kinase kinase kinase 3. (647 aa)
GRB2Growth factor receptor bound protein 2. (217 aa)
CACNA1FVoltage-dependent L-type calcium channel subunit alpha; Voltage-sensitive calcium channels (VSCC) mediate the entry of calcium ions into excitable cells and are also involved in a variety of calcium-dependent processes, including muscle contraction, hormone or neurotransmitter release, gene expression, cell motility, cell division and cell death; Belongs to the calcium channel alpha-1 subunit (TC 1.A.1.11) family. (1971 aa)
CAMK2BCalcium/calmodulin dependent protein kinase II beta. (653 aa)
ELK1Uncharacterized protein. (428 aa)
CDC42Uncharacterized protein. (191 aa)
GNAQG protein subunit alpha q. (359 aa)
HRASHRas proto-oncogene, GTPase. (189 aa)
ITPR3Inositol 1,4,5-trisphosphate receptor type 3. (2703 aa)
ADCY7Adenylate cyclase type 7; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling. (1095 aa)
EGFRReceptor protein-tyrosine kinase. (1210 aa)
RAF1Uncharacterized protein. (668 aa)
PLA2G4CPhospholipase A2 group IVC. (551 aa)
LOC104663799Uncharacterized protein. (246 aa)
CAMK2GCalcium/calmodulin dependent protein kinase II gamma. (559 aa)
PLD2Phospholipase. (933 aa)
GNASGNAS complex locus. (1041 aa)
MAP3K4Mitogen-activated protein kinase kinase kinase 4. (1611 aa)
PTK2BProtein tyrosine kinase 2 beta; Belongs to the protein kinase superfamily. Tyr protein kinase family. (1058 aa)
GNRH1Gonadoliberin; Stimulates the secretion of gonadotropins. Belongs to the GnRH family. (105 aa)
MAP3K2Mitogen-activated protein kinase kinase kinase 2. (637 aa)
ADCY6Adenylate cyclase 6; Belongs to the adenylyl cyclase class-4/guanylyl cyclase family. (603 aa)
ADCY3Adenylate cyclase type 3; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling. (1147 aa)
MAPK7Mitogen-activated protein kinase; Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. MAP kinase subfamily. (814 aa)
CALML6Calmodulin like 6. (181 aa)
PRKCAProtein kinase C; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. PKC subfamily. (672 aa)
EGR1Early growth response protein; Transcriptional regulator. Recognizes and binds to the DNA sequence 5'-GCG(T/G)GGGCG-3'(EGR-site) in the promoter region of target genes. Binds double-stranded target DNA, irrespective of the cytosine methylation status. Regulates the transcription of numerous target genes, and thereby plays an important role in regulating the response to growth factors, DNA damage, and ischemia. Plays a role in the regulation of cell survival, proliferation and cell death. Belongs to the EGR C2H2-type zinc-finger protein family. (541 aa)
ITPR1Inositol 1,4,5-trisphosphate receptor type 1. (2714 aa)
CALML4Calmodulin like 4. (192 aa)
Your Current Organism:
Rhinopithecus roxellana
NCBI taxonomy Id: 61622
Other names: Pygathrix roxellana, R. roxellana, golden snub-nosed monkey
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