76 items (Rhinopithecus roxellana) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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query proteins and first shell of interactors

white nodes:
second shell of interactors

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proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

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experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	ADCY8	Adenylate cyclase type 8; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling. (1043 aa)
	AKT1	Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily. (480 aa)
	SPDYE4	Speedy/RINGO cell cycle regulator family member E4. (237 aa)
	BRAF	B-Raf proto-oncogene, serine/threonine kinase. (761 aa)
	ADCY5	Adenylate cyclase 5; Belongs to the adenylyl cyclase class-4/guanylyl cyclase family. (864 aa)
	MAPK8	Mitogen-activated protein kinase. (427 aa)
	CPEB2	Uncharacterized protein. (491 aa)
	ANAPC10	Anaphase-promoting complex subunit 10; Component of the anaphase promoting complex/cyclosome (APC/C), a cell cycle-regulated E3 ubiquitin-protein ligase complex that controls progression through mitosis and the G1 phase of the cell cycle. (185 aa)
	PRKACB	Protein kinase cAMP-activated catalytic subunit beta; Belongs to the protein kinase superfamily. (398 aa)
	SPDYA	Speedy/RINGO cell cycle regulator family member A. (313 aa)
	RPS6KA6	Ribosomal protein S6 kinase. (732 aa)
	MAPK9	Mitogen-activated protein kinase. (387 aa)
	CPEB4	Cytoplasmic polyadenylation element binding protein 4. (729 aa)
	ADCY1	Adenylate cyclase type 1; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling. (1075 aa)
	GNAI2	G protein subunit alpha i2. (355 aa)
	MAD2L1	HORMA domain-containing protein. (205 aa)
	PRKACA	Protein kinase cAMP-activated catalytic subunit alpha; Belongs to the protein kinase superfamily. (351 aa)
	PIK3CA	Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit. (1068 aa)
	PIK3CD	Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit. (1044 aa)
	ADCY2	Adenylate cyclase type 2; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling. (1052 aa)
	PDE3B	Phosphodiesterase. (1113 aa)
	CCNB2	Cyclin N-terminal domain-containing protein; Belongs to the cyclin family. (398 aa)
	CPEB3	Cytoplasmic polyadenylation element binding protein 3. (716 aa)
	ANAPC4	Anaphase-promoting complex subunit 4; Component of the anaphase promoting complex/cyclosome (APC/C), a cell cycle-regulated E3 ubiquitin ligase that controls progression through mitosis and the G1 phase of the cell cycle. Belongs to the APC4 family. (812 aa)
	RPS6KA2	Protein kinase domain-containing protein. (200 aa)
	GNAI3	G protein subunit alpha i3. (354 aa)
	CDC26	Cell division cycle 26. (85 aa)
	ANAPC5	Anaphase promoting complex subunit 5. (755 aa)
	IGF1R	Tyrosine-protein kinase receptor. (1367 aa)
	GNAI1	G protein subunit alpha i1. (253 aa)
	MAP2K1	Mitogen-activated protein kinase kinase 1; Belongs to the protein kinase superfamily. (393 aa)
	AKT3	Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily. (479 aa)
	CDC23	Cell division cycle 23. (597 aa)
	PIK3R1	Phosphoinositide-3-kinase regulatory subunit 1. (724 aa)
	PGR	Progesterone receptor. (917 aa)
	BUB1	BUB1 mitotic checkpoint serine/threonine kinase. (1096 aa)
	CCNA1	Cyclin A1; Belongs to the cyclin family. (465 aa)
	RPS6KA3	Ribosomal protein S6 kinase. (742 aa)
	ANAPC13	Anaphase promoting complex subunit 13. (74 aa)
	ANAPC2	Anaphase promoting complex subunit 2; Belongs to the cullin family. (822 aa)
	CCNA2	Cyclin A2; Belongs to the cyclin family. (432 aa)
	CDC25B	Cell division cycle 25B. (566 aa)
	CPEB1	Cytoplasmic polyadenylation element binding protein 1. (613 aa)
	FZR1	Fizzy and cell division cycle 20 related 1. (546 aa)
	MAPK1	Mitogen-activated protein kinase. (330 aa)
	IGF1	Insulin-like growth factor I; The insulin-like growth factors, isolated from plasma, are structurally and functionally related to insulin but have a much higher growth-promoting activity. May be a physiological regulator of [1-14C]- 2-deoxy-D-glucose (2DG) transport and glycogen synthesis in osteoblasts. Stimulates glucose transport in bone-derived osteoblastic (PyMS) cells and is effective at much lower concentrations than insulin, not only regarding glycogen and DNA synthesis but also with regard to enhancing glucose uptake. May play a role in synapse maturation. Ca(2+)-dependent exo [...] (208 aa)
	MAPK14	Mitogen-activated protein kinase. (360 aa)
	ADCY9	Adenylate cyclase 9; Belongs to the adenylyl cyclase class-4/guanylyl cyclase family. (1353 aa)
	CDC27	Uncharacterized protein. (294 aa)
	PLK1	Serine/threonine-protein kinase PLK. (612 aa)
	MAPK10	Mitogen-activated protein kinase. (550 aa)
	MOS	MOS proto-oncogene, serine/threonine kinase; Belongs to the protein kinase superfamily. (346 aa)
	PKMYT1	Protein kinase, membrane associated tyrosine/threonine 1. (555 aa)
	PIK3R3	Phosphoinositide-3-kinase regulatory subunit 3. (461 aa)
	RPS6KA1	Ribosomal protein S6 kinase. (744 aa)
	MAPK3	Mitogen-activated protein kinase; Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. MAP kinase subfamily. (379 aa)
	KRAS	KRAS proto-oncogene, GTPase. (189 aa)
	AURKA	Protein kinase domain-containing protein; Belongs to the protein kinase superfamily. (403 aa)
	INS	Insulin; Insulin decreases blood glucose concentration. It increases cell permeability to monosaccharides, amino acids and fatty acids. It accelerates glycolysis, the pentose phosphate cycle, and glycogen synthesis in liver. (110 aa)
	KIF22	Kinesin-like protein; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family. (668 aa)
	ADCY7	Adenylate cyclase type 7; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling. (1095 aa)
	RAF1	Uncharacterized protein. (668 aa)
	ARAF	A-Raf proto-oncogene, serine/threonine kinase. (606 aa)
	CDC16	Cell division cycle 16. (620 aa)
	CDK1	Cyclin dependent kinase 1; Belongs to the protein kinase superfamily. (297 aa)
	CDC25A	Cell division cycle 25A. (524 aa)
	AKT2	Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily. (481 aa)
	ADCY6	Adenylate cyclase 6; Belongs to the adenylyl cyclase class-4/guanylyl cyclase family. (603 aa)
	ADCY3	Adenylate cyclase type 3; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling. (1147 aa)
	STK10	Serine/threonine kinase 10. (968 aa)
	MAD1L1	Mitotic arrest deficient 1 like 1. (718 aa)
	ANAPC7	Anaphase promoting complex subunit 7. (599 aa)
	CCNB1	Cyclin B1; Belongs to the cyclin family. (429 aa)
	HSP90AB1	HATPase_c domain-containing protein. (724 aa)
	PIK3CB	Phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit beta; Belongs to the PI3/PI4-kinase family. (1073 aa)
	SPDYC	Speedy/RINGO cell cycle regulator family member C. (293 aa)

Your Current Organism:

Rhinopithecus roxellana

NCBI taxonomy Id: 61622
Other names: Pygathrix roxellana, R. roxellana, golden snub-nosed monkey

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
ADCY1	ADCY2	ENSRROP00000009828	ENSRROP00000012552	Adenylate cyclase type 1; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling.	Adenylate cyclase type 2; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling.	0.485
ADCY1	ADCY3	ENSRROP00000009828	ENSRROP00000040934	Adenylate cyclase type 1; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling.	Adenylate cyclase type 3; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling.	0.945
ADCY1	ADCY5	ENSRROP00000009828	ENSRROP00000003576	Adenylate cyclase type 1; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling.	Adenylate cyclase 5; Belongs to the adenylyl cyclase class-4/guanylyl cyclase family.	0.455
ADCY1	ADCY6	ENSRROP00000009828	ENSRROP00000040839	Adenylate cyclase type 1; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling.	Adenylate cyclase 6; Belongs to the adenylyl cyclase class-4/guanylyl cyclase family.	0.454
ADCY1	ADCY7	ENSRROP00000009828	ENSRROP00000036529	Adenylate cyclase type 1; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling.	Adenylate cyclase type 7; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling.	0.515
ADCY1	ADCY8	ENSRROP00000009828	ENSRROP00000000304	Adenylate cyclase type 1; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling.	Adenylate cyclase type 8; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling.	0.956
ADCY1	ADCY9	ENSRROP00000009828	ENSRROP00000026575	Adenylate cyclase type 1; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling.	Adenylate cyclase 9; Belongs to the adenylyl cyclase class-4/guanylyl cyclase family.	0.663
ADCY1	AKT1	ENSRROP00000009828	ENSRROP00000002071	Adenylate cyclase type 1; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling.	Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily.	0.692
ADCY1	AKT2	ENSRROP00000009828	ENSRROP00000040614	Adenylate cyclase type 1; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling.	Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily.	0.692
ADCY1	AKT3	ENSRROP00000009828	ENSRROP00000021339	Adenylate cyclase type 1; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling.	Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily.	0.692
ADCY1	GNAI1	ENSRROP00000009828	ENSRROP00000019417	Adenylate cyclase type 1; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling.	G protein subunit alpha i1.	0.807
ADCY1	GNAI2	ENSRROP00000009828	ENSRROP00000009860	Adenylate cyclase type 1; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling.	G protein subunit alpha i2.	0.799
ADCY1	GNAI3	ENSRROP00000009828	ENSRROP00000017699	Adenylate cyclase type 1; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling.	G protein subunit alpha i3.	0.807
ADCY1	PDE3B	ENSRROP00000009828	ENSRROP00000013521	Adenylate cyclase type 1; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling.	Phosphodiesterase.	0.765
ADCY1	PRKACA	ENSRROP00000009828	ENSRROP00000011512	Adenylate cyclase type 1; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling.	Protein kinase cAMP-activated catalytic subunit alpha; Belongs to the protein kinase superfamily.	0.932
ADCY1	PRKACB	ENSRROP00000009828	ENSRROP00000005551	Adenylate cyclase type 1; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling.	Protein kinase cAMP-activated catalytic subunit beta; Belongs to the protein kinase superfamily.	0.934
ADCY2	ADCY1	ENSRROP00000012552	ENSRROP00000009828	Adenylate cyclase type 2; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling.	Adenylate cyclase type 1; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling.	0.485
ADCY2	ADCY5	ENSRROP00000012552	ENSRROP00000003576	Adenylate cyclase type 2; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling.	Adenylate cyclase 5; Belongs to the adenylyl cyclase class-4/guanylyl cyclase family.	0.762
ADCY2	ADCY6	ENSRROP00000012552	ENSRROP00000040839	Adenylate cyclase type 2; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling.	Adenylate cyclase 6; Belongs to the adenylyl cyclase class-4/guanylyl cyclase family.	0.752
ADCY2	ADCY7	ENSRROP00000012552	ENSRROP00000036529	Adenylate cyclase type 2; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling.	Adenylate cyclase type 7; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling.	0.444