STRINGSTRING
GSK3B GSK3B SOCS1 SOCS1 STAT5A STAT5A AKT1 AKT1 SOCS5 SOCS5 SOCS6 SOCS6 SOCS4 SOCS4 RELA RELA MAPK8 MAPK8 SOCS3 SOCS3 MAPK9 MAPK9 FOXO3 FOXO3 TNFSF11 TNFSF11 PRLR PRLR SHC4 SHC4 JAK2 JAK2 PIK3CA PIK3CA STAT5B STAT5B PIK3CD PIK3CD SOS1 SOS1 MAP2K2 MAP2K2 CISH CISH ELF5 ELF5 SHC1 SHC1 CCND1 CCND1 PRL PRL NRAS NRAS STAT3 STAT3 TNFRSF11A TNFRSF11A SRC SRC MAP2K1 MAP2K1 AKT3 AKT3 PIK3R1 PIK3R1 CCND2 CCND2 GCK GCK MAPK1 MAPK1 LHCGR LHCGR MAPK14 MAPK14 SOCS7 SOCS7 SOS2 SOS2 SLC2A2 SLC2A2 LHB LHB MAPK10 MAPK10 FOS FOS PIK3R3 PIK3R3 MAPK3 MAPK3 CSN2 CSN2 ESR2 ESR2 CYP17A1 CYP17A1 KRAS KRAS STAT1 STAT1 GRB2 GRB2 INS INS HRAS HRAS IRF1 IRF1 RAF1 RAF1 AKT2 AKT2 TH TH PIK3CB PIK3CB SOCS2 SOCS2 LOC104678360 LOC104678360 NFKB1 NFKB1
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
GSK3BGlycogen synthase kinase 3 beta; Belongs to the protein kinase superfamily. (309 aa)
SOCS1Suppressor of cytokine signaling 1. (215 aa)
STAT5ASignal transducer and activator of transcription. (905 aa)
AKT1Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily. (480 aa)
SOCS5Suppressor of cytokine signaling 5. (536 aa)
SOCS6Suppressor of cytokine signaling 6. (535 aa)
SOCS4Suppressor of cytokine signaling 4. (439 aa)
RELARELA proto-oncogene, NF-kB subunit. (551 aa)
MAPK8Mitogen-activated protein kinase. (427 aa)
SOCS3Suppressor of cytokine signaling 3. (225 aa)
MAPK9Mitogen-activated protein kinase. (387 aa)
FOXO3Forkhead box O3. (617 aa)
TNFSF11Tumor necrosis factor ligand superfamily member. (317 aa)
PRLRProlactin receptor; This is a receptor for the anterior pituitary hormone prolactin. (619 aa)
SHC4SHC adaptor protein 4. (630 aa)
JAK2Tyrosine-protein kinase. (1094 aa)
PIK3CAPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit. (1068 aa)
STAT5BSignal transducer and activator of transcription. (787 aa)
PIK3CDPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit. (1044 aa)
SOS1SOS Ras/Rac guanine nucleotide exchange factor 1. (1333 aa)
MAP2K2Mitogen-activated protein kinase kinase 2; Belongs to the protein kinase superfamily. (399 aa)
CISHCytokine inducible SH2 containing protein. (275 aa)
ELF5E74 like ETS transcription factor 5. (265 aa)
SHC1SHC adaptor protein 1. (574 aa)
CCND1Cyclin D1; Belongs to the cyclin family. (253 aa)
PRLProlactin. (228 aa)
NRASNRAS proto-oncogene, GTPase. (189 aa)
STAT3Signal transducer and activator of transcription. (802 aa)
TNFRSF11ATNF receptor superfamily member 11a. (595 aa)
SRCTyrosine-protein kinase. (540 aa)
MAP2K1Mitogen-activated protein kinase kinase 1; Belongs to the protein kinase superfamily. (393 aa)
AKT3Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily. (479 aa)
PIK3R1Phosphoinositide-3-kinase regulatory subunit 1. (724 aa)
CCND2Cyclin N-terminal domain-containing protein; Belongs to the cyclin family. (289 aa)
GCKPhosphotransferase. (466 aa)
MAPK1Mitogen-activated protein kinase. (330 aa)
LHCGRLutropin-choriogonadotropic hormone receptor; Receptor for lutropin-choriogonadotropic hormone. The activity of this receptor is mediated by G proteins which activate adenylate cyclase; Belongs to the G-protein coupled receptor 1 family. FSH/LSH/TSH subfamily. (699 aa)
MAPK14Mitogen-activated protein kinase. (360 aa)
SOCS7Suppressor of cytokine signaling 7. (584 aa)
SOS2SOS Ras/Rho guanine nucleotide exchange factor 2. (1332 aa)
SLC2A2Solute carrier family 2 member 2; Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family. (524 aa)
LHBCys_knot domain-containing protein. (141 aa)
MAPK10Mitogen-activated protein kinase. (550 aa)
FOSFos proto-oncogene, AP-1 transcription factor subunit. (380 aa)
PIK3R3Phosphoinositide-3-kinase regulatory subunit 3. (461 aa)
MAPK3Mitogen-activated protein kinase; Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. MAP kinase subfamily. (379 aa)
CSN2Beta-casein; Important role in determination of the surface properties of the casein micelles. (226 aa)
ESR2Estrogen receptor 2. (530 aa)
CYP17A1Cytochrome P450 family 17 subfamily A member 1; Belongs to the cytochrome P450 family. (508 aa)
KRASKRAS proto-oncogene, GTPase. (189 aa)
STAT1Signal transducer and activator of transcription. (787 aa)
GRB2Growth factor receptor bound protein 2. (217 aa)
INSInsulin; Insulin decreases blood glucose concentration. It increases cell permeability to monosaccharides, amino acids and fatty acids. It accelerates glycolysis, the pentose phosphate cycle, and glycogen synthesis in liver. (110 aa)
HRASHRas proto-oncogene, GTPase. (189 aa)
IRF1Interferon regulatory factor. (325 aa)
RAF1Uncharacterized protein. (668 aa)
AKT2Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily. (481 aa)
THTyrosine hydroxylase. (532 aa)
PIK3CBPhosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit beta; Belongs to the PI3/PI4-kinase family. (1073 aa)
SOCS2Suppressor of cytokine signaling 2. (198 aa)
LOC104678360Nuclear receptor domain-containing protein. (231 aa)
NFKB1Nuclear factor kappa B subunit 1. (975 aa)
Your Current Organism:
Rhinopithecus roxellana
NCBI taxonomy Id: 61622
Other names: Pygathrix roxellana, R. roxellana, golden snub-nosed monkey
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